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Registered Nurse - Research Clinic

Duke University Health System

Durham, North Carolina

Health system employer

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RN

Posted Aug 7, 2026 · Last seen active Aug 9, 2026

What the posting states

Shift
Rotating
Weekends, holidays, call
While designated a clinic, there is a requirement for occasional night and weekend shifts to cover the needs of these protocols.

About this role

Show full description
At Duke Health, we're driven by a commitment to compassionate care that changes the lives of patients, their loved ones, and the greater community. No matter where your talents lie, join us and discover how we can advance health together. About Duke University Hospital Pursue your passion for caring with Duke University Hospital in Durham, North Carolina, which is consistently ranked among the best in the United States. The largest of the four Duke Healthhospitals with 1062 patient beds, it features comprehensive diagnostic and therapeutic facilities, including a regional emergency/trauma center, an endo-surgery center, and more. Duke Nursing Highlights Duke University Health System is designated as a Magnet organization Nurses from each hospital are consistently recognized each year as North Carolina's Great 100 Nurses. Duke University Health System was awarded the American Board of Nursing Specialties Award for Nursing Certification Advocacy for being strong advocates of specialty nursing certification. Duke University Health System has 6000 + registered nurses Quality of Life: Living in the Triangle! Relocation Assistance (based on eligibility) DukeHealth's Inpatient Research Center seeks to hire a Clinical Nurse (Experienced or New Grad) who will embrace our mission of Advancing Health Together! Summary Clinic 3N oversees the management of participants who have agreed to be a part of a research protocol. The protocols vary and include pediatric to adult participants and visits range from same day appointments to multiple overnight stays. While designated a clinic, there is a requirement for occasional night and weekend shifts to cover the needs of these protocols. Schedule: Day/ Night Rotation with weekend schedules as needed. Job Duties Plan, provide and document professional nursing care in clinic, utilizing the nursing process, in accordance with physician orders, research protocols and established policies and procedures, under the supervision of the nurse manager, charge nurse or practice manager. Collect participant data in accordance with research protocols, evaluate nursing care provided, document and communicate appropriately nursing actions taken and participant responses. Delegate tasks and supervise the activities of other licensed and unlicensed care providers. Assist other nursing personnel in the delivery of participant care and serves as team leader. Monitor and initiate corrective action to maintain the environment of care, including equipment and material resources. Participate in own professional development by maintaining required competencies, identifying learning needs and seeking appropriate assistance or educational offerings. Support the development of other staff and formal learners. Participate in the identification of clinical, operational and safety related performance improvement opportunities. Ability to complete research protocol specific training in a timely manner Participate in clinic or entity level performance improvement activities. Perform other related duties in practical nurse and all unlicensed assistive personnel Knowledge of and appropriate application of the nursing process Knowledge of professional theory, practice and procedures Ability to teach research participants and families in accordance with the research protocols Ability to record activities, document assessments, plan of care, interventions, evaluation and re-evaluation of patient status Ability to navigate the entity to provide protocol driven care to research participants and to support clinical care should it be needed Minimum Requirements Must have an accredited Bachelor’s Degree in Nursing (or higher), Associate's Degree in Nursing or Nursing Diploma. All registered nurses without a Bachelor's degree in Nursing (or higher) will be required to enroll in an appropriate BSN program within two years of their start date and to complete the program within seven years of their start date. Must have current or compact RN license in the State of North Carolina. Nurses hired at Duke Health with a valid compact license are required to obtain their North Carolina nursing license within 90 days of their start date. BCLS certification is required. Pre-employment Physical Capacity Testing Required Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values. Essential Physical Job Functions Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

Skills for this role

research protocol managementparticipant data collectionnursing processdelegationpatient care documentationperformance improvementteaching research participantsprotocol-driven care

Certifications

BCLS

Requirements

  • current or compact RN license in the State of North Carolina
  • Nurses hired with a valid compact license are required to obtain their North Carolina nursing license within 90 days of their start date
  • for occasional night and weekend shifts to cover the needs of these protocols.

Benefits

  • Relocation Assistance

About the employer

Duke University Health System
Health system employer

Duke University Health System (DUHS) is the employer for this Registered Nurse position located in Mooresville, North Carolina, with the role based at Duke Regional Hospital. The hospital features a 28-bed Surgical Unit within its General Surgery/Bariatric department, providing care…

What reviewers appreciate

  • No prior experience required, making the position accessible to new graduate nurses
  • Structured Nurse Residency Program (DUHS) required for CNIs within 12 months, indicating formal onboarding support
  • Accepts compact RN licensure in addition to North Carolina licensure

What reviewers flag

  • BSN required, which may exclude ADN or diploma-prepared nurses
  • New graduates must complete the Nurse Residency Program within 12 months, adding a structured time-bound requirement
  • Unit covers six distinct surgical specialty areas, which may demand broad and rapidly adaptable clinical knowledge
professional nursingperformance improvementcollaborationstructured educationquality-focuseddelegation

Living in Durham, NC

Durham blends Southern charm with a revitalized downtown anchored by the historic American Tobacco District. Home to Duke University Hospital and a thriving food scene, the Bull City offers nurses a welcoming place to land.

Map showing the location of Durham, NC
Durham, NC on the map · © Mapbox © OpenStreetMap· Open the live map
Metro price level · Durham area
97.6
2% below the national average
Median gross rent
$1,508/mo
rent and tenant-paid utilities

U.S. Bureau of Economic Analysis · 2024 metro Regional Price Parities · Census ACS 2024

Browse open roles in Durham

Worth asking

The posting doesn’t answer these. Good ones to ask a recruiter or in the interview.

  • Can you walk me through the base pay range and differentials?
  • What should I expect for weekly hours, holiday, call, and rotation?
  • What orientation, preceptor time, and ongoing unit support are included?
  • How are patient load, floating, and staffing support handled day to day?
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