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Duke University Health System

Health system employer · Based in Mooresville, NC

See 36 open roles

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Duke University Health System photo

Life here

What a shift at Duke University Health System looks like

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Duke University Health System workplace

On the floor

What the day-to-day looks like

Shifts hiring now
Days 22 · Rotating 1

The city

Living in Durham, NC

Durham blends Southern charm with a revitalized downtown anchored by the historic American Tobacco District. Home to Duke University Hospital and a thriving food scene, the Bull City offers nurses a welcoming place to land.

Browse roles in Durham
Map showing the location of Durham, NC
Durham, NC on the map · © Mapbox © OpenStreetMap· Open the live map
Metro price level · Durham area
2% below the national average
BEA index 97.6 (100 = national)
Median gross rent
$1,508/mo
rent and tenant-paid utilities
Median household income
$81,619/yr
all local households, not nurse pay

U.S. Bureau of Economic Analysis · 2024 metro Regional Price Parities · Census ACS 2024

Who they are

The hospital features a 28-bed Surgical Unit within its General Surgery/Bariatric department, providing care across a diverse range of surgical specialties including general surgery, vascular, urology, colorectal, plastics, and bariatric patients.

  • Hiring days & rotating
  • Sign-on bonus · 5 roles
More about Duke University Health System

This breadth of patient types offers nurses exposure to multiple clinical areas within a single unit. The RN role encompasses planning and delivering professional nursing care, documenting care provided, delegating tasks to appropriate personnel, assisting other healthcare team members, and actively participating in performance improvement activities. The position requires graduation from an accredited BSN program, current or compact RN licensure in North Carolina, and BLS certification. Notably, no prior nursing experience is required, making this position accessible to new graduate nurses. For Clinical Nurse I (CNI) hires, DUHS requires completion of its Nurse Residency Program within 12 months of hire, indicating a structured support and onboarding pathway for early-career nurses. This requirement reflects the organization's investment in developing new nurses through formalized training. The combination of a multi-specialty surgical unit and a residency program suggests an environment focused on both clinical learning and professional development.

Working here

Culture and working life

professional nursingperformance improvementcollaborationstructured educationquality-focuseddelegationteamworkclinical development

What to consider

The good

  • No prior experience required, making the position accessible to new graduate nurses
  • Structured Nurse Residency Program (DUHS) required for CNIs within 12 months, indicating formal onboarding support
  • Accepts compact RN licensure in addition to North Carolina licensure
  • Diverse patient population across general surgery, vascular, urology, colorectal, plastics, and bariatric specialties
  • Emphasis on performance improvement activities, suggesting a culture of quality advancement

The hard parts

  • BSN required, which may exclude ADN or diploma-prepared nurses
  • New graduates must complete the Nurse Residency Program within 12 months, adding a structured time-bound requirement
  • Unit covers six distinct surgical specialty areas, which may demand broad and rapidly adaptable clinical knowledge

The reality check

Before you decide

Quick facts

Relationship
Umbrella organization
Roles last seen active
Sep 9, 2026
Workplace photos
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The units

Units hiring now

Open counts come from the live roles below. Grouped as the postings state them.

Open roles

Roles from Duke University Health System

Refreshed throughout the day.

Clinical Nurse II- Concierge Medicine

Duke University Health System · Health system employer

Durham, NC · Posted last week

  • RN
Apply

Registered Nurse - Oncology Infusion Duke Regional Durham, NC

Duke University Health System · Health system employer

Durham, NC · Posted last week

  • RN
Apply

Registered Nurse (RN) - General Medicine Stepdown

Duke University Health System · Health system employer

Durham, NC · Posted 6 days ago

  • New grads welcomed
  • RN
  • Compact license OK
Apply

Registered Nurse - Cancer Center Ports Durham, NC

Duke University Health System · Health system employer

Durham, NC · Posted 2 weeks ago

  • Magnet-designated
  • RN
  • Compact license OK
Apply

Registered Nurse II (RN) Ambulatory Clinic - Float Pool

Duke University Health System · Health system employer

Durham, NC · Posted 2 weeks ago

  • RN
  • 8-hour days
  • Compact license OK
Apply

Registered Nurse (RN) - Duke Raleigh Campus-Operating Room

Duke University Health System · Health system employer

Raleigh, NC · Posted last week

  • RN
  • 10-hour days
  • Compact license OK
Apply

Registered Nurse II- (RN) Duke Primary Care-Sweetwater

Duke University Health System · Health system employer

Durham, NC · Posted last week

  • RN
  • Day shift
Apply

Registered Nurse - Infusion Southpoint Durham, NC

Duke University Health System · Health system employer

Durham, NC · Posted last week

  • RN
  • Compact license OK
Apply

Clinical Nurse II- Vascular Surgery

Duke University Health System · Health system employer

Raleigh, NC · Posted last week

  • RN
  • 10-hour days
  • Compact license OK
Apply

Registered Nurse - Med Surg

Duke University Health System · Health system employer

Mooresville, NC · Posted last week

  • Sign-on bonus
  • RN
  • Compact license OK
  • ADN accepted
  • Magnet-designated hospital
Apply

Registered Nurse (CNII) - Duke Primary Care Mebane

Duke University Health System · Health system employer

Mebane, NC

  • RN
  • 8-hour days
Apply

Registered Nurse (RN) Infusion Education-Duke University Hosp.

Duke University Health System · Health system employer

Durham, NC

  • Magnet-designated
  • LPN
  • 8-hour days
  • Agency contract
Apply

Clinical Nurse II - Engagement Center

Duke University Health System · Health system employer

Durham, NC

  • RN
  • 8-hour days
  • Compact license OK
Apply

Clinical Nurse II- Urology

Duke University Health System · Health system employer

Raleigh, NC

  • RN
  • Day shift
  • Compact license OK
Apply

Clinical Nurse II-Dermatology

Duke University Health System · Health system employer

Raleigh, NC

  • RN
  • 8-hour days
  • Compact license OK
Apply

Clinical Nurse II- Orthopaedics

Duke University Health System · Health system employer

Morrisville, NC

  • RN
  • Day shift
  • Compact license OK
Apply

Registered Nurse - Hyperbaric Treatment

Duke University Health System · Health system employer

Durham, NC

  • RN
  • Day shift
  • Compact license OK
Apply

Clinical Nurse II- Vascular Surgery and Vein Center

Duke University Health System · Health system employer

Raleigh, NC

  • RN
  • 10-hour days
  • Per diem
Apply

Registered Nurse - Wound Clinic

Duke University Health System · Health system employer

Durham, NC

  • NP
  • 8-hour days
  • Compact license OK
Apply

Clinical Nurse II- Rheumatology Triage

Duke University Health System · Health system employer

Durham, NC

  • RN
  • Day shift
  • Compact license OK
Apply

Clinical Nurse II- Mohs Surgery

Duke University Health System · Health system employer

Durham, NC · Seen active yesterday

  • RN
  • 10-hour days
  • Compact license OK
Apply

Clinical Nurse II- GI Triage

Duke University Health System · Health system employer

Durham, NC

  • RN
  • 8-hour days
  • Compact license OK
Apply

Clinical Services Nurse - Spine Clinic 1B/1C

Duke University Health System · Health system employer

Durham, NC

  • RN
  • 8-hour days
  • Compact license OK
Apply

Registered Nurse - Float pool

Duke University Health System · Health system employer

Mooresville, NC

  • Sign-on bonus
  • RN
  • ADN accepted
  • Floating required
Apply

Registered Nurse - Sickle Cell

Duke University Health System · Health system employer

Durham, NC

  • RN
  • Day shift
  • Compact license OK
Apply

Registered Nurse - Infusion Clinic

Duke University Health System · Health system employer

Mooresville, NC

  • Sign-on bonus
  • RN
  • New grads welcomed
  • ADN accepted
Apply

Registered Nurse (RN) Infusion Clinic 3/12s

Duke University Health System · Health system employer

Durham, NC

  • RN
  • 12-hour days
  • Compact license OK
Apply

Registered Nurse - Duke South Urology Clinic 4/10s

Duke University Health System · Health system employer

Durham, NC

  • RN
  • 10-hour days
  • Compact license OK
Apply

Registered Nurse - Ortho Spine clinic

Duke University Health System · Health system employer

Mooresville, NC

  • Sign-on bonus
  • RN
  • Compact license OK
  • ADN accepted
Apply

Clinical Nurse II - Pulmonary Triage

Duke University Health System · Health system employer

Durham, NC

  • RN
  • Day shift
  • Compact license OK
Apply

Registered Nurse (RN) - Operating Room

Duke University Health System · Health system employer

Durham, NC · Seen active last week

  • Sign-on bonus
  • RN
Apply

Registered Nurse - Research Clinic

Duke University Health System · Health system employer

Durham, NC

  • New grads welcomed
  • RN
  • Day/ Night Rotation with weekend schedules as needed.
  • Clinic 3N
Apply

Clinical Service Nurse II

Duke University Health System · Health system employer

Raleigh, NC

  • RN
  • 8-hour days
  • Compact license OK
Apply

Registered Nurse (RN)- Surgical Care Unit-Duke University Hospital-36hrs

Duke University Health System · Health system employer

Durham, NC

  • RN
Apply

Registered Nurse - Endoscopy

Duke University Health System · Health system employer

Mooresville, NC

  • Magnet-designated
  • RN
Apply

Registered Nurse (RN) General Surgery

Duke University Health System · Health system employer

Durham, NC

  • New grads welcomed
  • RN
  • Compact license OK
Apply
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