Duke University Health System
Health system employer · Based in Mooresville, NC
Life here
What a shift at Duke University Health System looks like
On the floor
What the day-to-day looks like
- Shifts hiring now
- Days 22 · Rotating 1
The city
Living in Durham, NC
Durham blends Southern charm with a revitalized downtown anchored by the historic American Tobacco District. Home to Duke University Hospital and a thriving food scene, the Bull City offers nurses a welcoming place to land.
Browse roles in Durham- Metro price level · Durham area
- 2% below the national average
- BEA index 97.6 (100 = national)
- Median gross rent
- $1,508/mo
- rent and tenant-paid utilities
- Median household income
- $81,619/yr
- all local households, not nurse pay
U.S. Bureau of Economic Analysis · 2024 metro Regional Price Parities · Census ACS 2024
Who they are
The hospital features a 28-bed Surgical Unit within its General Surgery/Bariatric department, providing care across a diverse range of surgical specialties including general surgery, vascular, urology, colorectal, plastics, and bariatric patients.
- Hiring days & rotating
- Sign-on bonus · 5 roles
More about Duke University Health System
This breadth of patient types offers nurses exposure to multiple clinical areas within a single unit. The RN role encompasses planning and delivering professional nursing care, documenting care provided, delegating tasks to appropriate personnel, assisting other healthcare team members, and actively participating in performance improvement activities. The position requires graduation from an accredited BSN program, current or compact RN licensure in North Carolina, and BLS certification. Notably, no prior nursing experience is required, making this position accessible to new graduate nurses. For Clinical Nurse I (CNI) hires, DUHS requires completion of its Nurse Residency Program within 12 months of hire, indicating a structured support and onboarding pathway for early-career nurses. This requirement reflects the organization's investment in developing new nurses through formalized training. The combination of a multi-specialty surgical unit and a residency program suggests an environment focused on both clinical learning and professional development.
Working here
Culture and working life
What to consider
The good
- No prior experience required, making the position accessible to new graduate nurses
- Structured Nurse Residency Program (DUHS) required for CNIs within 12 months, indicating formal onboarding support
- Accepts compact RN licensure in addition to North Carolina licensure
- Diverse patient population across general surgery, vascular, urology, colorectal, plastics, and bariatric specialties
- Emphasis on performance improvement activities, suggesting a culture of quality advancement
The hard parts
- BSN required, which may exclude ADN or diploma-prepared nurses
- New graduates must complete the Nurse Residency Program within 12 months, adding a structured time-bound requirement
- Unit covers six distinct surgical specialty areas, which may demand broad and rapidly adaptable clinical knowledge
The reality check
Before you decide
Quick facts
- Relationship
- Umbrella organization
- Roles last seen active
- Sep 9, 2026
- Workplace photos
- 1
Weighing a first job here?
The license clock and the job hunt run at once, and new-grad windows do the deciding. Residency commitments carry fine print worth reading before you sign.
Work here?
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Units hiring now
Open counts come from the live roles below. Grouped as the postings state them.
Open roles
Roles from Duke University Health System
Refreshed throughout the day.
Clinical Nurse II- Concierge Medicine
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- RN
- CEU allowance
Registered Nurse - Oncology Infusion Duke Regional Durham, NC
Durham, NC · Posted last week
- RN
Registered Nurse (RN) - General Medicine Stepdown
Durham, NC · Posted 6 days ago
- New grads welcomed
- RN
- Compact license OK
Registered Nurse - Cancer Center Ports Durham, NC
Durham, NC · Posted 2 weeks ago
- Magnet-designated
- RN
- Compact license OK
Registered Nurse II (RN) Ambulatory Clinic - Float Pool
Durham, NC · Posted 2 weeks ago
- RN
- 8-hour days
- Compact license OK
Registered Nurse (RN) - Duke Raleigh Campus-Operating Room
Raleigh, NC · Posted last week
- RN
- 10-hour days
- Compact license OK
Registered Nurse II- (RN) Duke Primary Care-Sweetwater
Durham, NC · Posted last week
- RN
- Day shift
Registered Nurse - Infusion Southpoint Durham, NC
Durham, NC · Posted last week
- RN
- Compact license OK
Clinical Nurse II- Vascular Surgery
Raleigh, NC · Posted last week
- RN
- 10-hour days
- Compact license OK
Registered Nurse - Med Surg
Mooresville, NC · Posted last week
Registered Nurse (CNII) - Duke Primary Care Mebane
Mebane, NC
- RN
- 8-hour days
Registered Nurse (RN) Infusion Education-Duke University Hosp.
Durham, NC
- Magnet-designated
- LPN
- 8-hour days
- Agency contract
Clinical Nurse II - Engagement Center
Durham, NC
- RN
- 8-hour days
- Compact license OK
Clinical Nurse II- Urology
Raleigh, NC
- RN
- Day shift
- Compact license OK
Clinical Nurse II-Dermatology
Raleigh, NC
- RN
- 8-hour days
- Compact license OK
Clinical Nurse II- Orthopaedics
Morrisville, NC
- RN
- Day shift
- Compact license OK
Registered Nurse - Hyperbaric Treatment
Durham, NC
- RN
- Day shift
- Compact license OK
Clinical Nurse II- Vascular Surgery and Vein Center
Raleigh, NC
- RN
- 10-hour days
- Per diem
Registered Nurse - Wound Clinic
Durham, NC
- NP
- 8-hour days
- Compact license OK
Clinical Nurse II- Rheumatology Triage
Durham, NC
- RN
- Day shift
- Compact license OK
Clinical Nurse II- Mohs Surgery
Durham, NC · Seen active yesterday
- RN
- 10-hour days
- Compact license OK
Clinical Nurse II- GI Triage
Durham, NC
- RN
- 8-hour days
- Compact license OK
Clinical Services Nurse - Spine Clinic 1B/1C
Durham, NC
- RN
- 8-hour days
- Compact license OK
Registered Nurse - Float pool
Mooresville, NC
- Sign-on bonus
- RN
- ADN accepted
- Floating required
Registered Nurse - Sickle Cell
Durham, NC
- RN
- Day shift
- Compact license OK
Registered Nurse - Infusion Clinic
Mooresville, NC
- Sign-on bonus
- RN
- New grads welcomed
- ADN accepted
Registered Nurse (RN) Infusion Clinic 3/12s
Durham, NC
- RN
- 12-hour days
- Compact license OK
Registered Nurse - Duke South Urology Clinic 4/10s
Durham, NC
- RN
- 10-hour days
- Compact license OK
Registered Nurse - Ortho Spine clinic
Mooresville, NC
- Sign-on bonus
- RN
- Compact license OK
- ADN accepted
Clinical Nurse II - Pulmonary Triage
Durham, NC
- RN
- Day shift
- Compact license OK
Registered Nurse (RN) - Operating Room
Durham, NC · Seen active last week
- Sign-on bonus
- RN
Registered Nurse - Research Clinic
Durham, NC
- New grads welcomed
- RN
- Day/ Night Rotation with weekend schedules as needed.
- Clinic 3N
Clinical Service Nurse II
Raleigh, NC
- RN
- 8-hour days
- Compact license OK
Registered Nurse (RN)- Surgical Care Unit-Duke University Hospital-36hrs
Durham, NC
- RN
Registered Nurse - Endoscopy
Mooresville, NC
- Magnet-designated
- RN
Registered Nurse (RN) General Surgery
Durham, NC
- New grads welcomed
- RN
- Compact license OK
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