Clinical Nurse III - Outpatient Infusion Clinic

City of Hope

Irvine, California

Posted Jul 27

Shift and hours: 10-⁠hour4 shifts · 40 hours a week
Unit and setting: Oncology · Clinic
Term: Per Diem

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Weekends: No weekends

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Oncology is a specialty you move into. Chemo cards are the working credential; infusion hires in too.

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Original listing

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Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

We have a fantastic opportunity for an experienced Oncology Infusion Nurse at City of Hope Lennar Foundation Cancer Center, you are the forefront of providing specialized and compassionate care to patients undergoing chemotherapy. This role is multifaceted, encompassing a range of responsibilities aimed at ensuring the well-being of patients and supporting them through their cancer treatment journey.

As a valued member of the City of Hope nursing team, you play an instrumental role in enhancing the quality of life for cancer patients. Your expertise, empathy, and dedication contribute to creating a supportive and healing environment for individuals undergoing cancer treatment. To learn more about more City of Hope Lennar Foundation Cancer Center CLICK HERE.

Monday through Friday – 4/10 hours shifts.

As a successful candidate, you will

Assessing of Patients’ Health Status

Conduct thorough assessments of patients' health status before, during, and after chemotherapy infusion sessions. Monitor and document vital signs, symptoms, and overall response to treatment.

Care Planning and Implementation

Develop comprehensive care plans tailored to each patients’ unique needs and treatment regimen. Implement nursing interventions in line with established care plans, ensuring optimal outcomes.

Chemotherapy Administration

Administer chemotherapy support to patients and their families regarding the treatment process, potential side effects, and self-care strategies. Offer emotional support, fostering a caring and empathetic environment for patients facing the challenges of cancer.

Coordination of Care

Collaborate with interdisciplinary healthcare teams to coordinate patient care and ensure seamless transitions between various stages of treatment. Schedule and facilitate follow-up appointments, actively participating in the continuity of care.

Management of Side Effects

Assist patients in managing and coping with side effects and complications arising from cancer treatment. Proactively address and alleviate symptoms, collaborating with healthcare providers as needed.

Quality Improvement

Participate in quality improvement initiatives to enhance the overall are provided in the outpatient infusion clinic.

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.

What's around it?

In Irvine, CA

Irvine, CAFrom Census ACS 2024.

Living costs about 11% above the US average

Median rent: $2,997/mo
Household income: $136,719/yr, all local households, not nurse pay

Life in Irvine, CA

NeighborhoodsIrvine is a master-planned city of named villages: Woodbridge (two man-made lakes, 20-plus pools, single-family homes, condos, and townhomes), Northwood (pre-master-plan larger lots, mature trees, gated Northwood Pointe), University Park (walkable, UCI-adjacent mid-century homes for academics and professionals), Westpark (central freeway access for commuters), Oak Creek, Turtle Rock (foothills, hiking, city views, UCI proximity), Portola Springs (newer construction, Irvine Spectrum access), Great Park Neighborhoods, Quail Hill (luxury, Laguna Coast Wilderness access), plus Woodbury, Orchard Hills, and the Spectrum area. A 2026 affordable-village snapshot put medians around $732,950 in University Park, $745,050 in Woodbridge, $768,160 in Oak Creek, $798,725 in Northwood, and $815,446 in Westpark, versus citywide medians well over $1.6 million. Nurses and young professionals often land in University Park or Westpark, or look just outside to Costa Mesa and Newport Beach for a less suburban feel; Aliso Viejo, Laguna Niguel, and Mission Viejo are the nearby family-commute alternatives.

Irvine is a master-planned city of named villages: Woodbridge (two man-made lakes, 20-plus pools, single-family homes, condos, and townhomes), Northwood (pre-master-plan larger lots, mature trees, gated Northwood Pointe), University Park (walkable, UCI-adjacent mid-century homes for academics and professionals), Westpark (central freeway access for commuters), Oak Creek, Turtle Rock (foothills, hiking, city views, UCI proximity), Portola Springs (newer construction, Irvine Spectrum access), Great Park Neighborhoods, Quail Hill (luxury, Laguna Coast Wilderness access), plus Woodbury, Orchard Hills, and the Spectrum area. A 2026 affordable-village snapshot put medians around $732,950 in University Park, $745,050 in Woodbridge, $768,160 in Oak Creek, $798,725 in Northwood, and $815,446 in Westpark, versus citywide medians well over $1.6 million.

Nurses and young professionals often land in University Park or Westpark, or look just outside to Costa Mesa and Newport Beach for a less suburban feel; Aliso Viejo, Laguna Niguel, and Mission Viejo are the nearby family-commute alternatives.

Sources

As of Sep 11, 2026Source 1: ireneandricky.com Source 2: extraspace.com Source 3: stephanieyounggroup.com Source 4: reddit.com Source 5: facebook.com

Getting aroundIrvine is car-dependent, with a Walk Score of 43, Transit Score of 26, and Bike Score of 69. Westpark is the village repeatedly tied to freeway access; the 405 is the highway named near central lodging such as the Irvine Marriott, and John Wayne Airport is in town. The city sits about 40 miles south of Los Angeles—about 45 minutes in light traffic—and about 90 minutes north of San Diego. Sources do not spell out hospital parking or bus lines, but Hoag and Kaiser Permanente medical centers are the named healthcare employers, Aliso Viejo, Laguna Niguel, and Mission Viejo are recommended for a convenient drive into Irvine, and traffic is a consistent local complaint.

Irvine is car-dependent, with a Walk Score of 43, Transit Score of 26, and Bike Score of 69. Westpark is the village repeatedly tied to freeway access; the 405 is the highway named near central lodging such as the Irvine Marriott, and John Wayne Airport is in town. The city sits about 40 miles south of Los Angeles—about 45 minutes in light traffic—and about 90 minutes north of San Diego.

Sources do not spell out hospital parking or bus lines, but Hoag and Kaiser Permanente medical centers are the named healthcare employers, Aliso Viejo, Laguna Niguel, and Mission Viejo are recommended for a convenient drive into Irvine, and traffic is a consistent local complaint.

Sources

As of Sep 11, 2026Source 1: rent.com Source 2: redfin.com Source 3: stephanieyounggroup.com Source 4: youtube.com Source 5: facebook.com Source 6: hyatt.com

OutdoorsIrvine set aside more than 16,000–16,500 acres of parks and open space and more than 100 miles of off-street multi-use trails. Signature hikes are Bommer Canyon (views and seasonal wildflowers) and the Quail Hill Loop Trail, with Quail Hill also opening onto Laguna Coast Wilderness. Orange County Great Park adds the Great Park Sports Complex, picnic areas, and the Great Park Balloon ride from 400 feet; Woodbridge is built around two lakes with paths, sandy lagoons, boating, and fishing. San Joaquin Marsh and Wildlife Sanctuary is the birding stop, Tanaka Farms the 30-acre farm with wagon tours, and Newport Beach and Laguna Beach the nearby ocean.

Irvine set aside more than 16,000–16,500 acres of parks and open space and more than 100 miles of off-street multi-use trails. Signature hikes are Bommer Canyon (views and seasonal wildflowers) and the Quail Hill Loop Trail, with Quail Hill also opening onto Laguna Coast Wilderness.

Orange County Great Park adds the Great Park Sports Complex, picnic areas, and the Great Park Balloon ride from 400 feet; Woodbridge is built around two lakes with paths, sandy lagoons, boating, and fishing. San Joaquin Marsh and Wildlife Sanctuary is the birding stop, Tanaka Farms the 30-acre farm with wagon tours, and Newport Beach and Laguna Beach the nearby ocean.

Sources

As of Sep 11, 2026Source 1: destinationirvine.com Source 2: youtube.com Source 3: rent.com Source 4: stephanieyounggroup.com Source 5: hungryhuy.com

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Living in Irvine

Irvine is a master-planned Orange County city of villages—Woodbridge's lakes and 20-plus pools, University Park's walkable UCI streets, Westpark's freeway access, Northwood's mature lots—wrapped around 16,500 acres of parks and 100-plus miles of trails. Bommer Canyon, Quail Hill, and Orange County Great Park (with its 400-foot balloon) are local defaults; Newport and Laguna beaches sit a short drive away. Hoag and Kaiser Permanente anchor a strong healthcare job market. The tradeoff is cost and cars: median homes around $1.65–$1.71 million, one-bedrooms near $3,600, Transit Score 26, and traffic locals warn about. After a shift, people hit Irvine Spectrum for dining and improv, Diamond Jamboree for Asian food, or Izakaya Osen and SOL Mexican Cocina. IUSD schools and top-tier safety suit families; many single professionals also consider Costa Mesa or Newport Beach for a less suburban feel. Expect nearly 300 sunny days, Tanaka Farms in October, and September's Global Village Festival.

AI area guide

Sources

As of 2026Source 1: stephanieyounggroup.com Source 2: extraspace.com Source 3: destinationirvine.com Source 4: youtube.com Source 5: rent.com Source 6: redfin.com Source 7: storamericastorage.com Source 8: reddit.com

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The role and schedule

Worth asking

Ask Mira

Your fit

On your path

Original listing

As a successful candidate, you will

Assessing of Patients’ Health Status

Care Planning and Implementation

Chemotherapy Administration

Coordination of Care

Management of Side Effects

Quality Improvement

What's around it?

Irvine, CAiFrom Census ACS 2024.

Life in Irvine, CA

Moving for this role?

Nurses on this role

Nurses on this role

Life in Irvine, CA

Moving for this role?

Nurses on this role

Irvine, CAFrom Census ACS 2024.