Skip to content

85 nursing jobs in Irvine, CA

Irvine is a master-planned Orange County city known for top-rated schools, manicured parks, and a family-friendly feel. The Irvine Spectrum Center anchors dining and entertainment, while nearby Newport Beach offers coastal escapes. With major hospital systems and UC Irvine Medical Center, it's a solid SoCal landing spot for nurses seeking suburban comfort and career opportunity.

Irvine, CA on the map· Open the live map
LUMIAGE BEAUTY HEALTH workplace
LUMIAGE BEAUTY HEALTH — a workplace named in a current Irvine postingView LUMIAGE BEAUTY HEALTH →

Find a nursing job in Irvine

Hiring here: Hoag (14) · VITAS Healthcare (11) · City of Hope (6) · Kaiser Permanente (6) · Stars Behavioral Health Group (6) · Hoag Health System (4)

Lumiage Beauty Health

Irvine, CA

  • RN
  • Local contract
1 / 2
  • RN
  • Day shift
  • Floating required
1 / 2
  • Day shift
1 / 2

RN - IV Wellness Clinic Per-Diem

Hydration Room logoHydration Room

Irvine, CA

$45/hr

  • RN
  • Per diem
  • Floating required
Hydration Room logo

Hydration Room

Irvine, CA

  • RN
  • Per diem
  • Floating required
Stars Behavioral Health Group logo

Stars Behavioral Health Group

Irvine, CA

  • LVN
  • 8 Hour PM Shift
  • Coastal Star Crisis Stabilization Unit
Masimo logo

Masimo

Irvine, CA

Clinical Complaint Specialist

$80,000–$100,000/year

  • RN
AZAD Technology Partners logo

AZAD Technology Partners

Irvine, CA

  • RN
  • Day shift
  • Local contract

Competent Care Home Health, Inc.

Irvine, CA

  • LVN
  • 8-⁠hour evenings
Latitude Food Allergy Care logo

Latitude Food Allergy Care

Irvine, CA

  • RN

H2O Express Transport LLC

Irvine, CA

  • RN
  • Travel contract

Pedes Orange County

Irvine, CA

Outpatient LVN

$32–$36/hr

  • LVN

City of Hope

Irvine, CA

  • 10-⁠hour shifts
  • Per diem

Deluxe Med Spa

Irvine, CA

  • RN

OHMI ANTI-AGING Center

Irvine, CA

  • NP
ARCC Center Foundation logo

ARCC Center Foundation

Irvine, CA

  • Nights shift
  • +$6/hr differential
Hoag Health System logo

Hoag Health System

Irvine, CA · Health system employer

  • Magnet-designated
  • RN
  • 12-⁠hour nights
  • Per diem
BrightStar Care of Southern Orange County logo

BrightStar Care of Southern Orange County

Irvine, CA

  • RN
  • Rotating shift
  • Per diem
Hoag logo

Hoag

Irvine, CA

Patient Care Assistant I: Irvine GI Lab

Posted 5 days ago

$22–$34/hr

  • RN/LVN/CNA

Los Robles Healthcare

Irvine, CA

  • RN
Loyal Source logo

Loyal Source

Irvine, CA

Examiner Physician Assistant

$150,426–$180,426

Humangood

Irvine, CA

  • RN
  • 8-⁠hour rotating
  • ADN accepted
Silverado logo

Silverado

Irvine, CA

  • RN
  • Shift Schedule: PRN (Per Diem), Monday - Saturday, variable hours
  • Per diem
VTP Holdings logo

VTP Holdings

Irvine, CA

  • RN
MemorialCare logo

MemorialCare

Irvine, CA

  • NP
Mission Healthcare logo

Mission Healthcare

Irvine, CA

  • RN
  • 10-⁠hour shifts
  • Per diem
Kaiser Permanente logo

Kaiser Permanente

Irvine, CA · Health system employer

  • CRNA

Per Diem Staffing Systems, Inc.

Irvine, CA · Staffing partner

PACU RN

$76–$78/hr

  • RN
  • Per diem
Stars Behavioral Health Group logo

Stars Behavioral Health Group

Irvine, CA

  • RN
  • Monday - Friday 9:00 AM - 5:30 PM (Includes On-Call)
  • Coastal Star Crisis Stabilization Unit
Masimo logo

Masimo

Irvine, CA

  • RN
City of Hope logo

City of Hope

Irvine, CA

  • RN
  • Monday through Friday – 4/10 hours shifts.
Hoag Health System logo

Hoag Health System

Irvine, CA · Health system employer

  • New grads welcomed
  • RN
  • Rotating shift
Hoag logo

Hoag

Irvine, CA

  • Rotating shift

Per Diem Staffing Systems, Inc.

Irvine, CA · Staffing partner

  • RN
  • 12-⁠hour nights
  • Per diem
Stars Behavioral Health Group logo

Stars Behavioral Health Group

Irvine, CA

  • LVN
  • 8-⁠hour shifts
City of Hope logo

City of Hope

Irvine, CA

  • RN
  • 12-⁠hour nights
  • Per diem
Hoag Health System logo

Hoag Health System

Irvine, CA · Health system employer

  • Magnet-designated
  • RN
Hoag logo

Hoag

Irvine, CA

Charge Nurse: Irvine GI Lab

Posted 5 days ago

$63–$98/hr

  • RN
City of Hope logo

City of Hope

Irvine, CA

  • RN
  • ADN accepted
Hoag Health System logo

Hoag Health System

Irvine, CA · Health system employer

  • New grads welcomed · reported
  • LVN
  • Floating required
Hoag logo

Hoag

Irvine, CA

Clinic Nurse (RN) : Urology

Posted 6 days ago

$48–$74

  • RN
Hoag logo

Hoag

Irvine, CA

  • RN
City of Hope logo

City of Hope

Irvine, CA

  • LVN
  • Floating required
Hoag logo

Hoag

Irvine, CA

Clinical Nurse: Irvine Medical Oncology

Posted last week

$49–$81/hr

  • RN
Hoag logo

Hoag

Irvine, CA

LVN: Hoag Urgent Care Irvine

Closes Nov 8

$29–$46/hr

  • LVN

Working and living in Irvine

· 85 open roles

Posted hourly pay

RN
$56/hr median
$50–$63/hr middle half · 23 postings
LVN
$30/hr median
$29–$32/hr middle half · 6 postings

See roles with listed pay

Living costs

Median gross rent
$2,997/mo
Rent and tenant-paid utilities
Median household income
$136,719/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

2 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

6 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • CRNA1
  • NP2
  • RN62
  • LPN1
  • LVN14
  • CNA2

One posting may accept more than one credential.

Shifts listed

  • per-diem17
  • Days16
  • Nights9
  • Rotating6
  • Evenings4
  • weekend1

Postings may list several shifts or leave the shift unspecified.

Living in Irvine

Irvine is a master-planned Orange County city of villages—Woodbridge's lakes and 20-plus pools, University Park's walkable UCI streets, Westpark's freeway access, Northwood's mature lots—wrapped around 16,500 acres of parks and 100-plus miles of trails.

More about life here

Bommer Canyon, Quail Hill, and Orange County Great Park (with its 400-foot balloon) are local defaults; Newport and Laguna beaches sit a short drive away. Hoag and Kaiser Permanente anchor a strong healthcare job market.

The tradeoff is cost and cars: median homes around $1.65–$1.71 million, one-bedrooms near $3,600, Transit Score 26, and traffic locals warn about. After a shift, people hit Irvine Spectrum for dining and improv, Diamond Jamboree for Asian food, or Izakaya Osen and SOL Mexican Cocina.

IUSD schools and top-tier safety suit families; many single professionals also consider Costa Mesa or Newport Beach for a less suburban feel. Expect nearly 300 sunny days, Tanaka Farms in October, and September's Global Village Festival.

Sources
As of Sep 11, 2026
Neighborhoods

Irvine is a master-planned city of named villages: Woodbridge (two man-made lakes, 20-plus pools, single-family homes, condos, and townhomes), Northwood (pre-master-plan larger lots, mature trees, gated Northwood Pointe), University Park (walkable, UCI-adjacent mid-century homes for academics and professionals), Westpark (central freeway access for commuters), Oak Creek, Turtle Rock (foothills, hiking, city views, UCI proximity), Portola Springs (newer construction, Irvine Spectrum access), Great Park Neighborhoods, Quail Hill (luxury, Laguna Coast Wilderness access), plus Woodbury, Orchard Hills, and the Spectrum area. A 2026 affordable-village snapshot put medians around $732,950 in University Park, $745,050 in Woodbridge, $768,160 in Oak Creek, $798,725 in Northwood, and $815,446 in Westpark, versus citywide medians well over $1.6 million.

Nurses and young professionals often land in University Park or Westpark, or look just outside to Costa Mesa and Newport Beach for a less suburban feel; Aliso Viejo, Laguna Niguel, and Mission Viejo are the nearby family-commute alternatives.

Sources
Housing

Buying is expensive: citywide median sale prices are reported at about $1,654,500 to $1,710,000, with Orange County housing costs 156% above the national average. Condos are described from the mid-$800,000s; premium single-family homes run well over $2 million.

A 2026 affordable-village snapshot listed University Park around $732,950, Woodbridge $745,050, Oak Creek $768,160, Northwood $798,725, and Westpark $815,446. Renting a one-bedroom is cited around $3,595, with overall average rent around $3,105; cost of living is variously called 52% to almost 80% above the U.S. average. Newer and luxury inventory concentrates in Portola Springs, Great Park Neighborhoods, Quail Hill, and Turtle Rock.

Sources
Getting around

Irvine is car-dependent, with a Walk Score of 43, Transit Score of 26, and Bike Score of 69. Westpark is the village repeatedly tied to freeway access; the 405 is the highway named near central lodging such as the Irvine Marriott, and John Wayne Airport is in town. The city sits about 40 miles south of Los Angeles—about 45 minutes in light traffic—and about 90 minutes north of San Diego.

Sources do not spell out hospital parking or bus lines, but Hoag and Kaiser Permanente medical centers are the named healthcare employers, Aliso Viejo, Laguna Niguel, and Mission Viejo are recommended for a convenient drive into Irvine, and traffic is a consistent local complaint.

Sources
Food and dining

Diamond Jamboree is the go-to cluster for Asian flavors; named spots include Poached, Solstice, Ten Sushi, Izakaya Osen Irvine (Japanese gastropub small plates and cocktails), SOL Mexican Cocina (Baja-style tacos, seafood, margaritas), Andrei's Conscious Cuisine & Cocktails, and The Goldfinch. Irvine Spectrum Center is where locals go after 4 p.m. for restaurants, people-watching, and an improv show with dinner and drinks.

Hangar 24 Orange County is the craft-brewery tasting room; farmer's markets and international dining run citywide. For a harbor night, Newport Beach's Lido Marina Village has Nobu, Malibu Farm, Zinqué, and Herst Coffee—not in Irvine proper, but the usual nearby upgrade.

Sources
Outdoors

Irvine set aside more than 16,000–16,500 acres of parks and open space and more than 100 miles of off-street multi-use trails. Signature hikes are Bommer Canyon (views and seasonal wildflowers) and the Quail Hill Loop Trail, with Quail Hill also opening onto Laguna Coast Wilderness.

Orange County Great Park adds the Great Park Sports Complex, picnic areas, and the Great Park Balloon ride from 400 feet; Woodbridge is built around two lakes with paths, sandy lagoons, boating, and fishing. San Joaquin Marsh and Wildlife Sanctuary is the birding stop, Tanaka Farms the 30-acre farm with wagon tours, and Newport Beach and Laguna Beach the nearby ocean.

Sources
Arts and culture

September's Irvine Global Village Festival is the civic blowout—live music, dance, cultural exhibits, and international food. Irvine Spectrum Center handles shopping, the giant observation wheel, winter holiday attractions, and an improv comedy club.

Pretend City Children's Museum plus city museums and galleries cover family arts; Destination Irvine also flags performing arts and festivals. Nightlife is widely called limited and family-leaning, so evenings skew to Spectrum, Hangar 24 beer, or a drive to Newport's Lido Marina Village and Laguna rooftops such as Skyloft and The Rooftop Lounge.

Sources
Seasons and weather

Expect almost 300 sunny days, virtually no snow, and mild averages—about 73°F highs and 52°F lows—so hiking and trail time are year-round habits. Fall is Tanaka Farms season: a 30-acre pumpkin patch where you pick pumpkins off the vine, plus wagon rides, face painting, and harvest festivals.

Winter is holiday lights and attractions at Irvine Spectrum Center; Bommer Canyon is known for seasonal wildflowers. Heat is milder than inland Southern California, and Laguna Beach or Newport Beach is the local cooldown.

Sources
For families

Irvine Unified School District (IUSD) is consistently ranked among California's best, and UC Irvine adds a university-town layer. Safety is a defining pitch: 90% safer than other California cities, 70% safer than U.S. cities on average, crime 28% below the national average and mostly non-violent, and a ranking among the 15 safest cities in America.

Woodbridge (lakes, 20-plus pools, parks) and Northwood (larger lots, strong schools, Northwood Pointe) are the default family villages; Great Park Neighborhoods sit next to the sports complex. Pretend City Children's Museum and Tanaka Farms are the kid outings; Aliso Viejo, Laguna Niguel, and Mission Viejo are nearby family-friendly cities with Irvine commutes.

Sources
What locals say

People call Irvine clean, exceptionally safe, and convenient—shopping, restaurants, parks, and beaches are all a drive away, and the planned villages, schools, and trail network are why families stay. Healthcare and tech employers (Kaiser Permanente, Hoag, Broadcom, Blizzard Entertainment) are cited as a professional plus.

The honest cons are cost (among the priciest in Southern California), a suburban master-planned feel some find bland, thin nightlife versus Los Angeles or Anaheim, and traffic that one overview says will make you want to pull your hair out. Relocators who want less suburbia are pointed toward Costa Mesa or Newport Beach.

Sources

Other cities