85 nursing jobs in Irvine, CA
Irvine is a master-planned Orange County city known for top-rated schools, manicured parks, and a family-friendly feel. The Irvine Spectrum Center anchors dining and entertainment, while nearby Newport Beach offers coastal escapes. With major hospital systems and UC Irvine Medical Center, it's a solid SoCal landing spot for nurses seeking suburban comfort and career opportunity.
Find a nursing job in Irvine
Hiring here: Hoag (14) · VITAS Healthcare (11) · City of Hope (6) · Kaiser Permanente (6) · Stars Behavioral Health Group (6) · Hoag Health System (4)
Clinical Nurse II - Acute Rehab - Days - FT - Irvine
Irvine, CA
- RN
- Day shift
- Floating required
- LVN
- 8 Hour PM Shift
- Coastal Star Crisis Stabilization Unit
Interim Clinical Nurse Educator ? Maternal Child Health (Labor & Delivery and Postpartum) - 10/15/2026
Posted last week
$4,477 - $5,037 a month
- RN
- Day shift
- Local contract
LVN Respite Care Sat/Sun 2p-20p Irvine
$29–$32/hr
- LVN
- 8-hour evenings
Senior Manager, Clinical Product Quality - Medical Device/Complaint Handling & Cardiovascular RN
$145,000–$205,000/year
- RN
- 10-hour shifts
- Per diem
- Magnet-designated
- RN
- 12-hour nights
- Per diem
- RN
- Rotating shift
- Per diem
Examiner Physician Assistant
$150,426–$180,426
Registered Nurse (RN) Admissions
$55–$58/hr
- RN
- Shift Schedule: PRN (Per Diem), Monday - Saturday, variable hours
- Per diem
Hospice Admissions Registered Nurse / RN
$58–$62/hr
- RN
- 10-hour shifts
- Per diem
- CRNA
Crisis Stabilization Nursing Supervisor
$100,000–$110,000/year
- RN
- Monday - Friday 9:00 AM - 5:30 PM (Includes On-Call)
- Coastal Star Crisis Stabilization Unit
- RN
- Monday through Friday – 4/10 hours shifts.
- New grads welcomed
- RN
- Rotating shift
Clinical Nurse I: Irvine + Newport Beach Outpatient Treatment Center
Posted 4 days ago
$63/hr
$49–$77/hr
- Rotating shift
- RN
- 12-hour nights
- Per diem
- LVN
- 8-hour shifts
- Magnet-designated
- RN
- New grads welcomed · reported
- LVN
- Floating required
Clinical Practice Education Specialist (CPES) - ICU, Hematology, and Evaluation Treatment Center
$71–$113/hr
- RN
- Floating required
Working and living in Irvine
· 85 open roles
Posted hourly pay
- RN
- $56/hr median
- $50–$63/hr middle half · 23 postings
- LVN
- $30/hr median
- $29–$32/hr middle half · 6 postings
Living costs
- Median gross rent
- $2,997/mo
- Rent and tenant-paid utilities
- Median household income
- $136,719/yr
- All local households, not nurse pay
New to our board this week
6 current postings first appeared here in the past seven days.
Credentials accepted
- CRNA1
- NP2
- RN62
- LPN1
- LVN14
- CNA2
One posting may accept more than one credential.
Shifts listed
- per-diem17
- Days16
- Nights9
- Rotating6
- Evenings4
- weekend1
Postings may list several shifts or leave the shift unspecified.
Living in Irvine
Irvine is a master-planned Orange County city of villages—Woodbridge's lakes and 20-plus pools, University Park's walkable UCI streets, Westpark's freeway access, Northwood's mature lots—wrapped around 16,500 acres of parks and 100-plus miles of trails.
More about life hereShow less
Bommer Canyon, Quail Hill, and Orange County Great Park (with its 400-foot balloon) are local defaults; Newport and Laguna beaches sit a short drive away. Hoag and Kaiser Permanente anchor a strong healthcare job market.
The tradeoff is cost and cars: median homes around $1.65–$1.71 million, one-bedrooms near $3,600, Transit Score 26, and traffic locals warn about. After a shift, people hit Irvine Spectrum for dining and improv, Diamond Jamboree for Asian food, or Izakaya Osen and SOL Mexican Cocina.
IUSD schools and top-tier safety suit families; many single professionals also consider Costa Mesa or Newport Beach for a less suburban feel. Expect nearly 300 sunny days, Tanaka Farms in October, and September's Global Village Festival.
Sources
Neighborhoods
Irvine is a master-planned city of named villages: Woodbridge (two man-made lakes, 20-plus pools, single-family homes, condos, and townhomes), Northwood (pre-master-plan larger lots, mature trees, gated Northwood Pointe), University Park (walkable, UCI-adjacent mid-century homes for academics and professionals), Westpark (central freeway access for commuters), Oak Creek, Turtle Rock (foothills, hiking, city views, UCI proximity), Portola Springs (newer construction, Irvine Spectrum access), Great Park Neighborhoods, Quail Hill (luxury, Laguna Coast Wilderness access), plus Woodbury, Orchard Hills, and the Spectrum area. A 2026 affordable-village snapshot put medians around $732,950 in University Park, $745,050 in Woodbridge, $768,160 in Oak Creek, $798,725 in Northwood, and $815,446 in Westpark, versus citywide medians well over $1.6 million.
Nurses and young professionals often land in University Park or Westpark, or look just outside to Costa Mesa and Newport Beach for a less suburban feel; Aliso Viejo, Laguna Niguel, and Mission Viejo are the nearby family-commute alternatives.
Housing
Buying is expensive: citywide median sale prices are reported at about $1,654,500 to $1,710,000, with Orange County housing costs 156% above the national average. Condos are described from the mid-$800,000s; premium single-family homes run well over $2 million.
A 2026 affordable-village snapshot listed University Park around $732,950, Woodbridge $745,050, Oak Creek $768,160, Northwood $798,725, and Westpark $815,446. Renting a one-bedroom is cited around $3,595, with overall average rent around $3,105; cost of living is variously called 52% to almost 80% above the U.S. average. Newer and luxury inventory concentrates in Portola Springs, Great Park Neighborhoods, Quail Hill, and Turtle Rock.
Getting around
Irvine is car-dependent, with a Walk Score of 43, Transit Score of 26, and Bike Score of 69. Westpark is the village repeatedly tied to freeway access; the 405 is the highway named near central lodging such as the Irvine Marriott, and John Wayne Airport is in town. The city sits about 40 miles south of Los Angeles—about 45 minutes in light traffic—and about 90 minutes north of San Diego.
Sources do not spell out hospital parking or bus lines, but Hoag and Kaiser Permanente medical centers are the named healthcare employers, Aliso Viejo, Laguna Niguel, and Mission Viejo are recommended for a convenient drive into Irvine, and traffic is a consistent local complaint.
Food and dining
Diamond Jamboree is the go-to cluster for Asian flavors; named spots include Poached, Solstice, Ten Sushi, Izakaya Osen Irvine (Japanese gastropub small plates and cocktails), SOL Mexican Cocina (Baja-style tacos, seafood, margaritas), Andrei's Conscious Cuisine & Cocktails, and The Goldfinch. Irvine Spectrum Center is where locals go after 4 p.m. for restaurants, people-watching, and an improv show with dinner and drinks.
Hangar 24 Orange County is the craft-brewery tasting room; farmer's markets and international dining run citywide. For a harbor night, Newport Beach's Lido Marina Village has Nobu, Malibu Farm, Zinqué, and Herst Coffee—not in Irvine proper, but the usual nearby upgrade.
Outdoors
Irvine set aside more than 16,000–16,500 acres of parks and open space and more than 100 miles of off-street multi-use trails. Signature hikes are Bommer Canyon (views and seasonal wildflowers) and the Quail Hill Loop Trail, with Quail Hill also opening onto Laguna Coast Wilderness.
Orange County Great Park adds the Great Park Sports Complex, picnic areas, and the Great Park Balloon ride from 400 feet; Woodbridge is built around two lakes with paths, sandy lagoons, boating, and fishing. San Joaquin Marsh and Wildlife Sanctuary is the birding stop, Tanaka Farms the 30-acre farm with wagon tours, and Newport Beach and Laguna Beach the nearby ocean.
Arts and culture
September's Irvine Global Village Festival is the civic blowout—live music, dance, cultural exhibits, and international food. Irvine Spectrum Center handles shopping, the giant observation wheel, winter holiday attractions, and an improv comedy club.
Pretend City Children's Museum plus city museums and galleries cover family arts; Destination Irvine also flags performing arts and festivals. Nightlife is widely called limited and family-leaning, so evenings skew to Spectrum, Hangar 24 beer, or a drive to Newport's Lido Marina Village and Laguna rooftops such as Skyloft and The Rooftop Lounge.
Seasons and weather
Expect almost 300 sunny days, virtually no snow, and mild averages—about 73°F highs and 52°F lows—so hiking and trail time are year-round habits. Fall is Tanaka Farms season: a 30-acre pumpkin patch where you pick pumpkins off the vine, plus wagon rides, face painting, and harvest festivals.
Winter is holiday lights and attractions at Irvine Spectrum Center; Bommer Canyon is known for seasonal wildflowers. Heat is milder than inland Southern California, and Laguna Beach or Newport Beach is the local cooldown.
For families
Irvine Unified School District (IUSD) is consistently ranked among California's best, and UC Irvine adds a university-town layer. Safety is a defining pitch: 90% safer than other California cities, 70% safer than U.S. cities on average, crime 28% below the national average and mostly non-violent, and a ranking among the 15 safest cities in America.
Woodbridge (lakes, 20-plus pools, parks) and Northwood (larger lots, strong schools, Northwood Pointe) are the default family villages; Great Park Neighborhoods sit next to the sports complex. Pretend City Children's Museum and Tanaka Farms are the kid outings; Aliso Viejo, Laguna Niguel, and Mission Viejo are nearby family-friendly cities with Irvine commutes.
What locals say
People call Irvine clean, exceptionally safe, and convenient—shopping, restaurants, parks, and beaches are all a drive away, and the planned villages, schools, and trail network are why families stay. Healthcare and tech employers (Kaiser Permanente, Hoag, Broadcom, Blizzard Entertainment) are cited as a professional plus.
The honest cons are cost (among the priciest in Southern California), a suburban master-planned feel some find bland, thin nightlife versus Los Angeles or Anaheim, and traffic that one overview says will make you want to pull your hair out. Relocators who want less suburbia are pointed toward Costa Mesa or Newport Beach.