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Nursing Mastery

36 nursing jobs in Irvine, CA

Irvine is a master-planned Orange County city known for top-rated schools, manicured parks, and a family-friendly feel. The Irvine Spectrum Center anchors dining and entertainment, while nearby Newport Beach offers coastal escapes. With major hospital systems and UC Irvine Medical Center, it's a solid SoCal landing spot for nurses seeking suburban comfort and career opportunity.

Pay and living in Irvine

Map showing the location of Irvine, CA
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LUMIAGE BEAUTY HEALTH — a workplace named in a current Irvine postingView LUMIAGE BEAUTY HEALTH →

Find a nursing job in Irvine

Filter these on the boardView on the map
Oncology · 6Aesthetics · 3Home Health · 3Hospice & Palliative · 3Cardiac · 2ICU / Critical Care · 2Med Surg · 2Operating Room · 2

Hiring here: City of Hope (5) · Hoag Health System (4) · Hydration Room (2) · Masimo (2) · Per Diem Staffing Systems, Inc. (2) · TNAA Healthcare (2)

Aesthetic Registered Nurse

$58/hr

Lumiage Beauty Health

Irvine, CA

  • RN
  • Local contract
Apply
Hydration Room workplace

RN - IV Wellness Clinic Per-Diem

$55/hr

Hydration Room logoHydration Room

Irvine, CA

  • RN
  • Per diem
  • Floating required
Apply
A photo of UCI Health

Ambulatory Care Patient Supv - Infusion Center - FT Days

UCI Health logoUCI Health

Irvine, CA

  • Day shift
Apply
A photo of UC Irvine

Ambulatory Care Patient Supv - Infusion Center - FT Days

UC Irvine

Irvine, CA

  • Day shift
Apply

Registered Nurse (RN) - Per Diem

$45/hr

Hydration Room logoHydration Room

Irvine, CA

  • RN
  • Per diem
  • Floating required
Apply

Clinical Complaint Specialist

$43/hr

Masimo logoMasimo

Irvine, CA

  • RN
Apply

Pediatric Registered Nurse - Home Health- (FRI, SAT AND SUN) 4 hour shifts - Weekly Pay!

$58/hr

BrightStar Care of Southern Orange County logoBrightStar Care of Southern Orange County

Irvine, CA · Posted 2 days ago

  • RN
Apply

Hospice Admissions Registered Nurse / RN

$60/hr

Mission Healthcare logoMission Healthcare

Irvine, CA · Posted last week

  • RN
  • Per diem
  • Tuition reimbursement
Apply

Registered Nurse Pre-Assessment Testing II - Barranca Surgery Center

$55/hr

SCA Health logoSCA Health

Irvine, CA

  • RN
Apply

Registered Nurse (RN) – IV Specialist

$55/hr

VTP Holdings logoVTP Holdings

Irvine, CA

  • RN
Apply

Examiner Physician Assistant

$150,425.60–$180,425.60

Loyal Source logoLoyal Source

Irvine, CA

Apply

Team Manager

VITAS Healthcare

Irvine, CA

  • RN
  • Day shift
  • Tuition reimbursement
Apply

House Supervisor - Per Diem (Nights)

$78/hr

City of Hope

Irvine, CA · Posted 6 days ago

  • RN
  • 12-hour nights
  • Per diem
Apply

Senior Manager, Clinical Product Quality - Medical Device/Complaint Handling & Cardiovascular RN

$84/hr

Edwards Lifesciences

Irvine, CA · Posted last week

  • RN
Apply

Registered Nurse Home Health (Full-Time)

$58/hr

Los Robles Healthcare

Irvine, CA · Posted last week

  • RN
Apply

Outpatient LVN

$32/hr

Pedes Orange County

Irvine, CA · Posted 2 weeks ago

  • LVN
Apply

Experienced Aesthetic Laser Nurse (RN)

From $50/hr

Deluxe Med Spa

Irvine, CA

  • RN
Apply

Aesthetic Nurse Practitioner (NP) — RN also considered

$58/hr

OHMI ANTI-AGING Center

Irvine, CA

  • NP
Apply

LVN Hospice Nurse, Part Time

$30/hr

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Irvine, CA

  • LVN
  • Day shift
  • Per diem
Apply

Registered Nurse

$54/hr

Humangood

Irvine, CA

  • RN
  • 8-hour rotating
  • ADN accepted
Apply

Caregiver Assistant

$19/hr

ARCC Center Foundation logoARCC Center Foundation

Irvine, CA

  • Nights shift
  • +$6/hr differential
Apply

Clinical Nurse I-IV: NICU - Newport Beach and Irvine

$48/hr

Hoag Health System logoHoag Health System · Health system employer

Irvine, CA

  • Magnet-designated
  • RN
  • 12-hour nights
  • Per diem
Apply

Labor & Delivery Registered Nurse

$76/hr

Per Diem Staffing Systems, Inc. · Staffing partner

Irvine, CA

  • RN
  • 12-hour nights
  • Per diem
Apply

RN Wound

$2,980/week

TNAA Healthcare logoTNAA Healthcare · Staffing partner

Irvine, CA

  • RN
  • Travel contract
Apply

Clinical Research Lab RN II

$40/hr

Masimo logoMasimo

Irvine, CA · Posted last week

  • RN
Apply

Palliative Care Registered Nurse (RN)

VITAS Healthcare

Irvine, CA

  • RN
  • Tuition reimbursement
Apply

Clinical Nurse III - Outpatient Infusion Clinic

$78/hr

City of Hope

Irvine, CA

  • 10-hour shifts
  • Per diem
Apply

Clinical Nurse II Med Surg: Cardiac Rehab

Hoag Health System logoHoag Health System · Health system employer

Irvine, CA

  • New grads welcomed
  • RN
  • Rotating shift
  • Magnet-designated hospital
Apply

Postpartum Registered Nurse -Per Diem

$62/hr

Per Diem Staffing Systems, Inc. · Staffing partner

Irvine, CA

  • RN
  • 12-hour nights
  • Per diem
Apply

RN Home Health

$2,680/week

TNAA Healthcare logoTNAA Healthcare · Staffing partner

Irvine, CA

  • RN
  • Travel contract
Apply

RN III - Outpatient Clinic

$68/hr

City of Hope

Irvine, CA · Posted 6 days ago

  • RN
  • ADN accepted
Apply

Clinical Nurse : Irvine Sub ICU/Telemetry

Hoag Health System logoHoag Health System · Health system employer

Irvine, CA

  • Magnet-designated
  • RN
Apply

Clinical Practice Education Specialist (CPES) - ICU, Hematology, and Evaluation Treatment Center

$71/hr

City of Hope

Irvine, CA

  • RN
  • Floating required
Apply

LVN: Hoag Urgent Care Irvine

Hoag Health System logoHoag Health System · Health system employer

Irvine, CA

  • New grads welcomed · reported
  • LVN
  • Floating required
Apply

LVN III - VAD & Infusion Clinic

$32/hr

City of Hope

Irvine, CA

  • LVN
  • Floating required
Apply

Clinical Nurse III - Medical Surgical 3rd Floor, FT, Nights

$78/hr

City of Hope

Irvine, CA

  • RN
  • Night shift
  • +$6.50/hr differential
Apply

Working and living in Irvine

· 36 open roles in this snapshot

Posted hourly pay

RN
$54/hr median
$49–$63/hr middle half · 15 postings

See roles with listed pay

Living costs

Median gross rent
$2,997/mo
Rent and tenant-paid utilities
Median household income
$136,719/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

2 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

4 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • NP1
  • RN26
  • LVN4

One posting may accept more than one credential.

Shifts listed

  • per-diem7
  • Nights5
  • Days4
  • Rotating2

Postings may list several shifts or leave the shift unspecified.

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