Saint Francis Health System
Health system in Cape Girardeau, MO
- Sign-on bonus up to $50,000 on 7+ roles
- Hiring days and nights
From 89 postings · Employer research Jul 14, 2026
The short version
Saint Francis Health System is a healthcare organization located in Tulsa, Oklahoma (74133).
Employer research, Jul 14, 2026
Who it fits
Best fit
- LPNs and LVNs: 11 of the 48 roles on this page accept an LPN or LVN
- Nurse practitioners: 6 of the 48 roles on this page are advanced practice roles
Nursing here
Workplace photos
The hard parts
Overnight shifts (3p-3a) required for some positions
Employer research, Jul 14, 2026
Variable scheduling with every other weekend required
Employer research, Jul 14, 2026
Inconsistent experience requirements across postings may create uncertainty for applicants regarding entry-level eligibility
Employer research, Jul 14, 2026
What to ask
- How is base pay set for the role, and which differentials apply?
- Which shifts are open, and what are the weekend, holiday and call rules?
- How long is orientation, and will I have one preceptor?
- What is the usual patient load, and how often do nurses float?
- Which hospital or site, and which unit, would I work on?
- Which requirements must I meet before applying, and which can wait until after hire?
Living in CAPE GIRARDEAU, MO
Positioned on the Mississippi between St. Louis and Memphis, Cape Girardeau combines effortless 11- to 13-minute hospital commutes with living costs roughly 14% below the national average. Choose between historic lofts on Spanish Street and suburban Walden Park, then spend off-shifts exploring riverfront patios downtown or hiking the bluffs at Trail of Tears State Park.
Browse roles in CAPE GIRARDEAU- Metro price level · CAPE GIRARDEAU area
- 14% below the national average
- BEA index 86.1 (100 = national)
- Median gross rent
- $876/mo
- rent and tenant-paid utilities
- Median household income
- $55,658/yr
- all local households, not nurse pay
U.S. Bureau of Economic Analysis · 2024 metro Regional Price Parities · Census ACS 2024
Common questions
Does Saint Francis Health System hire new grads?
4 of the 48 roles on this page ask for nursing experience, and none says it welcomes new grads.
Is there a sign-on bonus?
Yes, on 7 of the 48 roles on this page, up to $50,000.
Which shifts are open?
Of the 39 roles with a stated shift on this page, 21 are day shifts, 9 are night shifts, 7 are rotating shifts and 2 are weekends only.
Which units are hiring?
Stepdown (7), ICU (2), OR (2), cath lab (1) and more.
How do I apply?
Choose a role and press Apply. Your application comes to our team, we send it to Saint Francis Health System, and we tell you what happens next.
Roles from Saint Francis Health System
Registered Nurse I (Virtual) - Virtual Nursing
Posted 6 days ago
- RN
- RN
- 12-hour days
Registered Nurse I Med Surg 7 Tower
Posted yesterday
- RN
- Day shift
Surgical 1st Assistant - Operating Room (OR)
Posted today
- Sign-on bonus
- APRN
- Sign-on bonus
- APRN
Case Manager
Posted today
- RN
- Day shift
LPN II 2 South Observation
Posted last week
- LPN
Registered Nurse (RN) - Float Pool, PRN
Posted 5 days ago
- RN
- Per diem
LPN or MA - Physician Office (Farmington)
Posted 6 days ago
- LPN
- Day shift
Nurse Care Manager
Posted last week
- Day shift
CRNA - PRN
Posted last week
- CRNA
- Per diem
CRNA - PRN
Posted last week
- CRNA
- Per diem
CRNA - PRN
Posted last week
- CRNA
- Per diem
LPN or MA - Advanced Orthopedic Specialists
Posted last week
- LPN
- Day shift
LPN or MA - Cape Cardiology
Posted last week
- LPN
- Day shift
LPN or MA - Cape Physician Associates
Posted last week
- LPN
- Day shift
CRNA - W2 or 1099 option available
Posted last week
- Sign-on bonus
- CRNA
- Rotating shift
LPN or MA - Cape Neurology Specialists
Posted last week
- LPN
- Day shift
LPN or MA - Cape Pain Management
Posted last week
- LPN
- Day shift
Assistant Manager (RN)- Intensive Care Unit (ICU)
Posted last week
- RN
- Day shift
Nurse Assistant (NA)/ Certified Nurse Assistant (CNA) - Progressive Care Unit, Weekend Option
Posted last week
- CNA
- Weekend shift
Nurse Assistant, Same Day Surgery
Posted last week
- Rotating shift
Nurse Assistant, Post Anesthesia Care
Posted last week
- Rotating shift
Nurse Assistant, Same Day Surgery
Posted last week
- Rotating shift
- CNA
- Day shift
- CNA
- Night shift
- CNA
- Day shift
Nurse Assistant - Cath Lab
Posted last week
- Day shift
- CNA
- Night shift
- CNA
- Night shift
- CNA
- Day shift
- CNA
- Night shift
- CNA
- Night shift
Nurse Assistant - Pediatrics
Posted last week
- Night shift
Nursing Student Externship
Posted last week
- LPN
- Per diem
Nurse Assistant - Pediatrics
Posted last week
- Night shift
Registered Nurse (RN), Same Day Surgery
Posted last week
- RN
- Rotating shift
- Per diem
Registered Nurse (RN), Same Day Surgery
Posted last week
- RN
- Rotating shift
Registered Nurse (RN), Same Day Surgery
Posted last week
- RN
- Rotating shift
- Sign-on bonus
- LPN
- Night shift
- Sign-on bonus
- RN
- Weekend shift
Registered Nurse (RN) - Cape Care for Women
Posted last week
- RN
- Day shift
Graduate Practical Nurse (GPN)/ Licensed Practical Nurse (LPN) - Progressive Care Unit
Posted last week
- Sign-on bonus
- LPN
- Day shift
Registered Nurse (RN) - Vascular Surgery
Posted last week
- RN
- Day shift
Registered Nurse - Center for Digestive Diseases
Posted last week
- RN
- Day shift
Registered Nurse - Wound Center
Posted last week
- RN
- Day shift
LPN or MA - Physician Office (Sikeston)
Posted last week
- LPN
- Day shift
Graduate Nurse (GN)/ Registered Nurse (RN) - Neurosciences
Posted last week
- Sign-on bonus
- RN
- Night shift
Showing 48 of 89.
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Get certified in whatever you keep gravitating toward. After my wound care certification it was like new glasses: I saw what I had not known to look for.
“Willingly, had they accepted me, I would have worked for the wounded, in return for bread and water.”