121 nursing jobs in CAPE GIRARDEAU, MO
Positioned on the Mississippi between St. Louis and Memphis, Cape Girardeau combines effortless 11- to 13-minute hospital commutes with living costs roughly 14% below the national average. Choose between historic lofts on Spanish Street and suburban Walden Park, then spend off-shifts exploring riverfront patios downtown or hiking the bluffs at Trail of Tears State Park.
Find a nursing job in CAPE GIRARDEAU
Hiring here: Saint Francis Health System (73) · Saint Francis Healthcare (21) · UHS (8) · Saint Francis Medical Partners, LLC (4) · Life Care Center of Cape Girardeau (3) · Vetted Solutions (3)
Psychiatric Nurse
$24–$31/hr
- RN
- 8-hour days
- Tuition reimbursement
Registered Nurse (RN), Same Day Surgery
Cape Girardeau, MO · Posted last week
- RN
- Day, Variable Start Time, Monday - Friday
- Per diem
LPN Licensed Practical Nurse
Cape Girardeau, MO
- Sign-on bonus
- LPN/LVN
- RN
- 12-hour days
- Travel contract
Registered Nurse (RN), Same Day Surgery
Posted last week
- RN
- Day, Variable Start Time, Monday - Friday
- Per diem
- Sign-on bonus
- LPN/LVN
Advanced Practice Registered Nurse- Physician Office-Electrophysiology
Cape Girardeau, MO
- RN
- 8-hour days

Saint Francis Healthcare
18 open roles · day & night shifts
Saint Francis Healthcare
18 open roles · day & night shifts
Registered Nurse (RN) - Cape Care for Women
Cape Girardeau, MO
- New grads welcomed
- RN
- Monday-Friday 8:00am-4:30pm
Graduate Nurse (GN)/ Registered Nurse (RN) - Progressive Care Unit, Weekend Option
Cape Girardeau, MO
- Sign-on bonus
- RN
- Night Shift, 7pm to 7am, weekend option
- New grads welcomed
LPN or MA - Cape Cardiology
Cape Girardeau, MO
- LPN
- Monday-Friday 8:00am-4:30pm
Graduate Practical Nurse (GPN)/ Licensed Practical Nurse (LPN) - Progressive Care Unit
Cape Girardeau, MO
- Sign-on bonus
- LPN
- Day Shift, 7am to 7pm, every other weekend and holiday rotation
Registered Nurse (RN) - Vascular Surgery
Cape Girardeau, MO
- RN
- Day shift
Graduate Nurse (GN)/ Registered Nurse (RN) - Neurosciences
Cape Girardeau, MO
- Sign-on bonus
- RN
- Day Shift, 7am to 7pm, every other weekend and holiday rotation.
- New grads welcomed
Graduate Nurse (GN)/ Registered Nurse (RN) - Neurosciences
Cape Girardeau, MO
- Sign-on bonus
- RN
- Day Shift, 7am to 7pm, every other weekend and holiday rotation.
- New grads welcomed
Registered Nurse - Center for Digestive Diseases
Cape Girardeau, MO
- New grads welcomed
- RN
- Monday-Friday 7:30am-4:00pm, rotating on-call every 8 weeks
LPN or MA - Cape Neurology Specialists
Cape Girardeau, MO
- LPN
- Monday-Friday 8:00am-4:30pm
Registered Nurse - Wound Center
Cape Girardeau, MO
- New grads welcomed
- RN
- Monday-Friday 8:00am-4:30pm
LPN - Cape Physician Associates (Pediatrics)
Cape Girardeau, MO
- LPN
- 8-hour days
- Per diem
LPN or MA - Clinic Float Pool
Cape Girardeau, MO
- LPN
- 8-hour days
- Tuition reimbursement
Registered Nurse (RN) - Intensive Care Unit (ICU)
Cape Girardeau, MO
- Sign-on bonus
- RN
- 12-hour nights
- Tuition reimbursement
Graduate Nurse (GN)/Registered Nurse (RN) - Inpatient Rehab
Cape Girardeau, MO
- Sign-on bonus
- RN
- Night Shift, 7pm to 7am, every other weekend and holiday rotation
- New grads welcomed
Graduate Practical Nurse (GPN)/ Licensed Practical Nurse (LPN) - Progressive Care Unit
Cape Girardeau, MO
- Sign-on bonus
- LPN
- Night Shift, 7pm to 7am, every other weekend and holiday rotation
- New grads welcomed · reported
Lead RN - Cape Neurology Specialists
Cape Girardeau, MO
- RN
- 8-hour days
Registered Nurse (RN) - Emergency Room
Cape Girardeau, MO
- Sign-on bonus
- RN
- 12-hour nights
- ADN accepted
- Sign-on bonus
- RN
- Sign-on bonus
- LPN
- Day shift
- Tuition reimbursement
CRNA - W2 or 1099 option available
Posted last week
- Sign-on bonus
- CRNA
- Rotating shift
Neonatal Nurse Practitioner - PRN
Posted last week
- NP
- Per diem
Registered Nurse - Night Shift
$42–$46/hr
- New grads welcomed
- RN
- Night shift
CRNA - PRN
Posted last week
- CRNA
- Per diem
Nurse Practitioner -PRN- Same Day Surgery/PACU-
Posted last week
- NP
- Per diem
CRNA - PRN
Posted last week
- CRNA
- Per diem
Neonatal NP/PA - $15,000 Signing Bonus plus Relocation!
Posted last week
- Sign-on bonus
- NP
- Day shift
CRNA - PRN
Posted last week
- CRNA
- Per diem
Neonatal Nurse Practitioner - PRN
Posted last week
- NP
- Per diem
Saint Francis Health System
11 open roles
Saint Francis Health System
11 open roles
Surgical 1st Assistant - Operating Room (OR)
Cape Girardeau, MO · Posted today
- Sign-on bonus
- APRN
Surgical 1st Assistant - Operating Room (OR), Open Heart (CVOR)
Cape Girardeau, MO · Posted today
- Sign-on bonus
- APRN
Case Manager
Cape Girardeau, MO · Posted today
- RN
- Day shift
Registered Nurse (RN) - Float Pool, PRN
Cape Girardeau, MO · Posted 5 days ago
- RN
- Per diem
Registered Nurse (RN) - Level III NICU
Cape Girardeau, MO · Posted last week
- RN
- Night shift
Nurse Assistant (NA)/ Certified Nurse Assistant (CNA) - Progressive Care Unit
Cape Girardeau, MO · Posted last week
- CNA
- Night shift
Nurse Assistant (NA)/ Certified Nurse Assistant (CNA) - Progressive Care Unit, Weekend Option
Cape Girardeau, MO · Posted last week
- CNA
- Weekend shift
Nursing Student Externship
Cape Girardeau, MO · Posted last week
- LPN
- Per diem
Registered Nurse (RN) - Acute Care - Internal Traveler
Cape Girardeau, MO · Posted last week
- RN
- Day shift
Graduate Nurse (GN)/ Registered Nurse (RN) - Progressive Care Unit, Weekend Option
Cape Girardeau, MO · Posted last week
- Sign-on bonus
- RN
- Weekend shift
Hospice Nurse - RN
Cape Girardeau, MO · Posted last week
- Sign-on bonus
- RN
- Day shift
Working and living in CAPE GIRARDEAU
· 121 open roles
Living costs
- Median gross rent
- $876/mo
- Rent and tenant-paid utilities
- Median household income
- $55,658/yr
- All local households, not nurse pay
New to our board this week
8 current postings first appeared here in the past seven days.
Credentials accepted
- CRNA4
- NP4
- APRN2
- RN74
- LPN22
- LVN2
- CNA9
One posting may accept more than one credential.
Shifts listed
- Days53
- Nights28
- per-diem16
- Rotating9
- weekend5
Postings may list several shifts or leave the shift unspecified.
