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76 nursing jobs in Littleton, CO

Ten miles south of Denver, Littleton pairs Front Range foothill access with historic independence. Recharge post-shift along the South Platte River at Breckenridge Brewery or stroll Main Street past Palenque and Town Hall Arts Center. From Columbine West’s mid-century ranches to Ken Caryl Valley, 200 miles of trails and Chatfield State Park sit right at your doorstep.

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AdventHealth Porter workplace
AdventHealth Porter — a workplace named in a current Littleton postingView AdventHealth Porter →

Find a nursing job in Littleton

Hiring here: Portercare Adventist Health System (44) · AdventHealth (5) · Incredible Health (5) · AdventHealth Porter (2) · AllHealth Network (2) · Life Care Center of Littleton (2)

AdventHealth Porter logo

AdventHealth Porter

Littleton, CO

  • RN
  • Day shift
  • ADN accepted
1 / 2

LPN Licensed Practical Nurse

Life Care Center of Littleton

Littleton, CO

$31–$36/hr

  • LPN
  • +$2/hr differential
1 / 2

Registered Nurse - RN

Minimally Invasive Procedure Specialists logoMinimally Invasive Procedure Specialists

Littleton, CO

$30–$50/hr

  • RN
  • Day shift
AdventHealth Porter logo

AdventHealth Porter

Littleton, CO

  • RN
  • Day shift
  • ADN accepted
1 / 2

Registered Nurse

Life Care Center of Littleton

Littleton, CO

$40–$47/hr

  • RN
  • +$2/hr differential
  • ADN accepted

AllHealth Network

Littleton, CO

  • Sign-on bonus
  • RN

Rocky Mountain Infectious Disease Specialists, P.C.

Littleton, CO

  • RN
  • Day shift
  • Per diem

Willowbrook Place Memory Care

Littleton, CO

  • Memory Care

Portercare Adventist Health System

Littleton, CO · Health system employer

  • Sign-on bonus
  • RN
  • Night shift
  • ADN accepted

Highline South ASC

Littleton, CO

Moderate Sedation RN

Posted 4 days ago

$30–$55/hr

  • RN

MedCurate, Inc.

Littleton, CO

  • RN
  • Day shift
  • Per diem

South Denver Surgery Center (12708)

Littleton, CO

RN PreOP PACU

$34–$53/hr

  • RN
  • 10-⁠hour days

Highlands Behavioral Health System

Littleton, CO · Health system employer

  • Sign-on bonus
  • RN
  • 12-⁠hour days
  • +$4/hr differential
Optimal Home Care Inc logo

Optimal Home Care Inc

Littleton, CO

  • RN
  • Rotating shift
  • Per diem

IVI RMA Global

Littleton, CO

Registered Nurse

$75,000–$82,000

  • RN
  • Day shift

MGA Home Healthcare Colorado LLC

Littleton, CO

RN/LPN

Posted last week

$37,000–$106,000/year

  • New grads welcomed
  • RN/LPN

Incredible Health

Littleton, CO

  • Magnet-designated
  • RN
  • Rotating shift
  • Tuition reimbursement
Encompass Health logo

Encompass Health

Littleton, CO

Registered Nurse

Posted last week

$45–$62

  • Sign-on bonus
  • RN
  • Tuition reimbursement
United Surgical Partners International, Inc logo

United Surgical Partners International, Inc

Littleton, CO

  • RN
  • Day shift

AllHealth Network

Littleton, CO

  • Sign-on bonus
  • RN

Portercare Adventist Health System

Littleton, CO · Health system employer

  • Sign-on bonus
  • RN
  • Night shift

Incredible Health

Littleton, CO

Registered Nurse - Med Surg

$62,000–$102,000/year

  • Magnet-designated
  • RN
  • Night shift
  • ADN accepted

Portercare Adventist Health System

26 open roles · night & day shifts · Permanent

Registered Nurse Oncology FT Nights

Littleton, CO · Posted 5 days ago

$35–$60

  • Sign-on bonus
  • RN
  • Night shift

Assistant Nurse Manager - Neuro Trauma ICU

Littleton, CO · Posted 6 days ago

$39–$72

  • RN
  • Day shift

CVICU Assistant Nurse Manager

Littleton, CO · Posted last week

$39–$72

  • RN
  • Day shift

registered nurse

Littleton, CO · Posted last week

$34–$59

  • RN
  • Night shift
  • ADN accepted

Registered Nurse Med Surg FT Days

Littleton, CO · Posted last week

$35–$60

  • Sign-on bonus
  • RN
  • Day shift
  • ADN accepted

RN Charge Nurse Emergency Department

Littleton, CO · Posted last week

$35–$66

  • RN
  • Night shift
  • ADN accepted

RN Charge Nurse

Littleton, CO · Posted last week

$35–$65

  • RN
  • Night (United States of America)
  • ADN accepted

Registered Nurse - Operating Room Circulator

Littleton, CO · Posted last week

$35–$66

  • Sign-on bonus
  • RN
  • Full-Time Days
  • ADN accepted

Registered Nurse for Infusion FT Days

Littleton, CO · Posted 2 weeks ago

$35–$60

  • RN
  • Day shift
  • ADN accepted

Registered Nurse Neuro Trauma ICU Nights

Littleton, CO · Posted last week

$35–$60

  • Sign-on bonus
  • RN
  • Night shift
  • ADN accepted

Registered Nurse (RN) - CVICU

Littleton, CO · Posted last week

$35–$60

  • Sign-on bonus
  • RN
  • Night (United States of America)
  • ADN accepted

Registered Nurse Cardiovascular Operating Room

Littleton, CO · Posted last week

$35–$66

  • Sign-on bonus
  • RN
  • FT Days
  • ADN accepted

Registered Nurse Med Surg Ortho FT Nights

Littleton, CO · Posted last week

$35–$60

  • Sign-on bonus
  • RN
  • Night shift
  • ADN accepted

Registered Nurse Acute Care FT Nights

Littleton, CO · Posted last week

$35–$60

  • Sign-on bonus
  • RN
  • Night shift
  • ADN accepted

Charge Nurse (RN) - CVICU

Littleton, CO · Posted last week

$35–$66

  • Sign-on bonus
  • RN
  • Night shift
  • ADN accepted

Registered Nurse Cardiac Telemetry FT Days

Littleton, CO · Posted last week

$35–$60

  • RN
  • Day shift
  • ADN accepted

Registered Nurse Med Surg FT Nights

Littleton, CO · Posted last week

$35–$60

  • Sign-on bonus
  • RN
  • Night shift
  • ADN accepted

Registered Nurse Cardiac Telemetry FT Days

Littleton, CO · Posted last week

$35–$60

  • Sign-on bonus
  • RN
  • Day shift
  • ADN accepted

Registered Nurse RN CVOR Full Time Days

Littleton, CO · Posted last week

$35–$65

  • RN
  • Day shift
  • ADN accepted

Registered Nurse Float Pool FT Days

Littleton, CO · Posted last week

$35–$60

  • Sign-on bonus
  • RN
  • Day shift
  • ADN accepted

Registered Nurse Cardiac Tele PT Days

Littleton, CO · Posted last week

$35–$60

  • RN
  • Day shift
  • ADN accepted

Assistant Nurse Manager EP

Littleton, CO · Posted last week

$39–$72

  • RN
  • Day shift
  • ADN accepted

Registered Nurse Neuro Tele FT Nights

Littleton, CO · Posted last week

$35–$60

  • Sign-on bonus
  • RN
  • Night shift
  • ADN accepted

Registered Nurse Cardiac Telemetry FT Nights

Littleton, CO · Posted last week

$35–$60

  • Sign-on bonus
  • RN
  • Night shift
  • ADN accepted

Registered Nurse Operating Room

Littleton, CO · Posted last week

$35–$66

  • RN
  • Day shift
  • ADN accepted

Assistant Nurse Manager Operating Room Circulator Evenings

Littleton, CO · Posted last week

$39–$72

  • RN
  • Schedule: Full time Shift: Day (United States of America)
  • ADN accepted

Working and living in Littleton

· 76 open roles

Posted hourly pay

RN
$35/hr median
$34–$38/hr middle half · 14 postings

See roles with listed pay

Living costs

Median gross rent
$1,819/mo
Rent and tenant-paid utilities
Median household income
$98,839/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

3 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

6 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • RN72
  • LPN4
  • LVN1

One posting may accept more than one credential.

Shifts listed

  • Days36
  • Nights25
  • Rotating3
  • per-diem3

Postings may list several shifts or leave the shift unspecified.

Living in Littleton

Littleton offers healthcare professionals a rare blend of independent small-town charm and immediate Front Range foothill access, positioned roughly ten miles south of downtown Denver.

More about life here

Rather than blending into generic suburban sprawl, the city centers around a genuine historic Main Street filled with local staples like Palenque, independent coffee shops, and live theater at the Town Hall Arts Center. Outdoor-focused shift workers thrive here, with immediate access to 200 miles of regional trails along the High Line Canal, water sports at Chatfield State Park, and gatherings at the Farm House at Breckenridge Brewery campus.

Residential options span from turn-of-the-century bungalows near the center to mid-century properties in Columbine West and amenity-rich neighborhoods like Grant Ranch and Ken Caryl Valley. The principal tradeoff lies in transit geography: Santa Fe Drive and C-470 serve as the primary corridors, and commuting north toward central Denver or navigating peak hospital shift changes can feel bottlenecked compared to communities hugging the I-25 corridor.

Nevertheless, for nurses wanting safe neighborhoods, top-tier schools, and a tight-knit community feel, Littleton remains a standout Front Range destination.

Sources
As of Sep 16, 2026
Neighborhoods

Nurses and relocating professionals frequently target historic Downtown Littleton for its walkable streets and proximity to independent eateries, or established enclaves like Columbine West, known for mature trees, wide roads, and proximity to Clement Park. Further west against the foothills, Ken Caryl Valley offers townhomes and larger single-family layouts with extensive private trail systems, while Grant Ranch features a master-planned community with a private lake and clubhouse.

Newer master-planned communities like Sterling Ranch in the southwest corridor provide modern builds, contrasting with character properties and mid-century renovations nearer to Main Street.

Sources
Housing

Housing stock ranges widely from turn-of-the-century character homes surrounding downtown to mid-century ranches in neighborhoods like Columbine West, which often present more attainable entry points despite updating needs. Planned subdivisions like Grant Ranch and Ken Caryl Valley incorporate townhomes and single-family properties with community amenities, although buyers in these districts navigate mandatory HOA fees and limited turnover.

Farther southwest, master-planned expansions like Sterling Ranch provide brand-new construction for those seeking modern floor plans.

Sources
Getting around

Littleton sits along Denver's southwestern edge, primarily relying on Santa Fe Drive (US-85) and Broadway as primary north-south conduits, while the C-470 loop wraps around the southern and western perimeters to connect toward I-25 and the Denver Tech Center. While local travel within the suburb averages under twenty-five minutes, heading north into central Denver or major regional medical centers can see peak congestion along Santa Fe and regional arteries.

Compared to eastern neighbors like Centennial, Littleton has fewer redundant direct highway arteries heading straight into central Denver, making proximity to transit nodes or C-470 advantageous.

Sources
Food and dining

Downtown Littleton along Main Street serves as the culinary anchor, featuring walkable local favorites such as Palenque, Cencalli, and Bistro 36. Casual dining and craft beverages are prominent throughout the area, including the sprawling Farm House at Breckenridge Brewery campus on the South Platte River, ViewHouse, and community staples like Pinball Pub. Littleton also celebrates its culinary community with annual events like Littleton Restaurant Week, which highlights dozens of neighborhood establishments.

Sources
Outdoors

Littleton provides direct access to expansive recreation, encompassing over 1,400 acres of green space and 200 miles of trails. The High Line Canal trail and South Platte River path offer miles of paved and gravel walking and cycling routes, while nearby Chatfield State Park supports boating, camping, and watersports.

Local recreation hubs like Clement Park and the botanical grounds of Hudson Gardens and Events Center offer open space, walking trails, and outdoor community programming against the Front Range foothills.

Sources
Arts and culture

Cultural life centers on historic Main Street, home to independent art galleries and the Town Hall Arts Center, which stages year-round community theater, concerts, and musicals. The Littleton Museum offers living history with its 19th-century working farm and outdoor exhibits, while Hudson Gardens hosts seasonal concerts and community gatherings.

Public art is woven throughout the core, celebrated via self-guided walking mural strolls and lively community gatherings like local farmers markets.

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Seasons and weather

Residents experience distinct four-season weather with abundant year-round sunshine characteristic of the Colorado Front Range. Summers bring warm, sunny days suited for outdoor patios, river activities, and trails, while winters deliver occasional heavy snowfalls that generally melt rapidly under clear skies, with world-class ski resorts accessible a couple of hours west via the mountain corridor.

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For families

Littleton is widely favored by families for its established residential character, low turnover, and strong community engagement. Neighborhoods around Dakota Ridge and Denver Christian, along with established subdivisions like Columbine West and Grant Ranch, offer access to parks, community pools, and youth sports facilities.

The area's well-regarded public schools, safe residential streets, and extensive municipal recreation network make it an enduring target for family stability.

Sources
What locals say

Residents praise Littleton for delivering a genuine small-town community vibe backed by abundant sunshine, scenic foothill views, safe parks, and a bustling independent downtown that avoids generic suburban sprawl. However, locals note that housing availability is frequently tight due to low turnover in established subdivisions, older mid-century houses often require significant updating, and highway connectivity into north Denver can feel restricted compared to suburbs flanking the I-25 corridor.

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