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MUSC

Academic medical center in Charleston, SC

  • Hiring days and nights
  • New grads welcome on 2 roles
See 17 open roles
MUSC workplace

From 17 postings and the employer’s site · Employer research Jul 4, 2026Sources

The short version

The Medical University of South Carolina (MUSC), founded in 1824 in Charleston, is the state's only integrated academic health sciences center and home to the oldest medical school in the South.

Employer research, Jul 4, 2026

Who it fits

Best fit

  • New grads: 2 of 17 roles welcome new grads

Nursing here

Nurse-to-patient

1:4 to 1:5

MUSC · employer research

The hard parts

  • Fair pay identified as a key area for improvement in nurse reviews

    Employer research, Jul 4, 2026

  • Management rated lowest among all sub-categories at 3.2 out of 5 on Indeed

    Employer research, Jul 4, 2026

  • High patient acuity in specialty areas—ED acuity reported as nearly double the national average—creating demanding workload conditions

    Employer research, Jul 4, 2026

  • Job security and advancement rated below average at 3.4 out of 5

    Employer research, Jul 4, 2026

What to ask

  • How is base pay set for the role, and which differentials apply?
  • Which shifts are open, and what are the weekend, holiday and call rules?
  • How long is orientation, and will I have one preceptor?
  • What is the usual patient load, and how often do nurses float?
  • Which requirements must I meet before applying, and which can wait until after hire?

Living in Charleston, SC

Charleston, SC on the map· Open the live map

With a cost of living just 1% above the national average, Charleston offers coastal living without extreme sticker shock. Relocating nurses often bypass pricey Peninsula and Mount Pleasant enclaves for accessible townhomes in West Ashley, Avondale, and Park Circle, balancing historic Lowcountry charm against practical carrying costs like flood exposure.

Browse roles in Charleston
Metro price level · Charleston area
1% above the national average
BEA index 101.0 (100 = national)
Median gross rent
$1,722/mo
rent and tenant-paid utilities
Median household income
$92,414/yr
all local households, not nurse pay

U.S. Bureau of Economic Analysis · 2024 metro Regional Price Parities · Census ACS 2024

Common questions

Does MUSC hire new grads?

2 of 17 roles welcome new grads.

Which shifts are open?

Of the 3 roles with a stated shift, 1 is a day shift, 1 is a night shift and 1 is a rotating shift.

Which units are hiring?

Med surg (2), oncology (2), PACU (2), psych (2) and more.

How do I apply?

Choose a role and press Apply. Your application comes to our team, we send it to MUSC, and we tell you what happens next.

Current openings at MUSC

MUSC

Florence, SC

  • RN
  • Night shift
  • Compact license OK

MUSC

Orangeburg, SC

  • RN
  • 8-⁠hour 8 hour

MUSC

Charleston, SC

  • RN

MUSC

North Charleston, SC

  • RN
  • Compact license OK

MUSC

Charleston, SC

  • RN
  • 12-⁠hour rotating
  • Compact license OK

MUSC

Florence, SC

  • RN
  • Per diem
  • Compact license OK
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From nurses, to nurses

“We tried to imagine how loved ones for whom we might be solicitous would react were they in the place of the patients whom we hoped to serve.”

Lillian Wald

Keep some distance from the chronic complainers on your unit. Of everything that spreads in a hospital, negativity spreads fastest.

a psych nurse, 52 years in, a nursing school feature, 2024