MUSC
Academic Medical Center · Charleston, SC
- 17
- open roles, live count
- 1:4 to 1:5
- nurse-to-patient, employer research
- 3.4
- Google rating
Life here
What a shift at MUSC looks like
On the floor
What the day-to-day looks like
- Setting
- Academic Medical Center
- Shifts hiring now
- Days 1 · Nights 1 · Rotating 1
The city
Living in Charleston, SC
Charleston blends Southern charm with coastal living, where historic architecture and horse-drawn carriages line cobblestone streets. Nurses drawn to warm weather and beach access will find a growing healthcare corridor anchored by the Medical University of South Carolina. The city's food scene and nearby barrier islands make off-duty hours feel like a permanent vacation.
Browse roles in Charleston- Metro price level · Charleston area
- 1% above the national average
- BEA index 101.0 (100 = national)
- Median gross rent
- $1,722/mo
- rent and tenant-paid utilities
- Median household income
- $92,414/yr
- all local households, not nurse pay
U.S. Bureau of Economic Analysis · 2024 metro Regional Price Parities · Census ACS 2024
Who they are
The Medical University of South Carolina (MUSC), founded in 1824 in Charleston, is the state's only integrated academic health sciences center and home to the oldest medical school in the South.
- Academic Medical Center · Charleston
- Hiring days & nights & rotating
More about MUSC
MUSC operates through six colleges—Dental Medicine, Graduate Studies, Health Professions, Medicine, Nursing, and Pharmacy—educating over 3,000 students and 850 residents and fellows annually. Its clinical arm, MUSC Health, delivers patient care across university hospitals, research facilities, clinics, and patient care sites serving communities throughout South Carolina. In 2021, MUSC secured more than $328 million in biomedical research funding, leading the state in that category. For nursing professionals, MUSC offers exposure to a broad spectrum of specialties including surgical acute care, cardiothoracic surgery, interventional cardiology, hematology/oncology, vascular surgery, GI surgery, women's services, and a specialty emergency department located in the state-of-the-art Ashley River Tower. The environment is fast-paced and academically rigorous, with the specialty ED reportedly handling patient acuity nearly double the national average. New graduate RN positions are available across multiple units, indicating structured pathways for early-career nurses. The organization emphasizes teamwork, innovation, and its mission of preserving and optimizing human life through education, research, and patient care.
MUSC's mission statement: 'MUSC is a public institution of higher learning with the purpose of preserving and optimizing human life in South Carolina and beyond through education, research and patient care.' The organization promotes innovation in health transformation, impact through eliminating health disparities and expanding access, and influence extending beyond geographical boundaries. Comparably data indicates 100% employee alignment with the mission, vision, and values, though this is based on a small sample of 119 employee participants.
Working here
Culture and working life
What to consider
Indeed reports an overall rating of 3.6 out of 5 stars for Registered Nurse roles at MUSC, based on 911 reviews. Detailed sub-ratings: Work-life balance 3.7/5, Pay and benefits 3.5/5, Job security and advancement 3.4/5, Management 3.2/5, and Culture 3.5/5. Nurses report appreciation for a clear sense of purpose, feeling of personal appreciation, and the ability to learn new things. The primary area flagged for improvement is fair pay for the job. Management received the lowest sub-rating at 3.2/5. Comparably data shows 119 employee participants with 1,125 total ratings, and reports 100% mission alignment among respondents.
The good
- Clear sense of purpose and mission-driven culture appreciated by nursing staff
- Ability to learn new things in a leading academic medical center environment
- Feeling of personal appreciation reported by employees
- Teamwork and innovation emphasized, particularly in specialty units like the Ashley River Tower ED
- Wide range of specialty areas providing diverse clinical experience including cardiothoracic surgery, interventional cardiology, hematology/oncology, and vascular surgery
- New graduate RN positions available across multiple units, indicating structured entry-level pathways
The hard parts
- Fair pay identified as a key area for improvement in nurse reviews
- Management rated lowest among all sub-categories at 3.2 out of 5 on Indeed
- High patient acuity in specialty areas—ED acuity reported as nearly double the national average—creating demanding workload conditions
- Job security and advancement rated below average at 3.4 out of 5
The reality check
Before you decide
Quick facts
- Relationship
- Direct employer
- Roles last seen active
- Aug 2, 2026
- Workplace photos
- 1
- Website
- getcare.muschealth.org ↗
Weighing a first job here?
The license clock and the job hunt run at once, and new-grad windows do the deciding. Residency commitments carry fine print worth reading before you sign.
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Units hiring now
Open counts come from the live roles below. Grouped as the postings state them.
Open roles
Current openings at MUSC
Refreshed throughout the day.
- RN
- Night shift
- Compact license OK
Registered Nurse I (Fall 2026 New Grad Blitz) - R. Keith Summey Ambulatory Pre/Post
North Charleston, SC
- RN
- Day shift
Registered Nurse I (Fall2026 New Grad Blitz) - ART Acute Care & Surgical Acute Care
Charleston, SC
- New grads welcomed
- RN
- Ratio 1:4–1:5
Registered Nurse I (Fall 2026 New Grad Blitz) - ART Specialty ER/Chest Pain Center
Charleston, SC
- RN
Registered Nurse I (Fall 2026 New Grad Blitz) - Institute of Psychiatry: Adult Inpatient
Charleston, SC
- RN
Registered Nurse I (Fall 2026 New Grad Blitz) - Main Neuroscience Stepdown and Acute Care
Charleston, SC
- New grads welcomed
- RN
- Residency program
Registered Nurse I (Fall 2026 New Grad Blitz) - Institute of Psychiatry: 1N Acute Care Unit (ACU)
Charleston, SC
- RN
- RN
- RN
Registered Nurse I (new graduate) & II - ART 7W Bone Marrow Transplant
Charleston, SC
- RN
- 12-hour rotating
- Compact license OK
- RN
- Per diem
- Compact license OK
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