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28 nursing jobs in Charleston, SC

Charleston blends Southern charm with coastal living, where historic architecture and horse-drawn carriages line cobblestone streets. Nurses drawn to warm weather and beach access will find a growing healthcare corridor anchored by the Medical University of South Carolina. The city's food scene and nearby barrier islands make off-duty hours feel like a permanent vacation.

TNAA Healthcare workplace
TNAA Healthcare — a workplace named in a current Charleston posting
HealthTrust Workforce Solutions photo
Employer photoHiring organization

Registered Nurse (RN) | Cardiovascular Operating Room (CVOR) - Contract - Days

Charleston, South Carolina 29406

Pay not listedView role
MUSC workplace
Workplace photo

MUSC

Labor & Delivery Registered Nurse II

Charleston, South Carolina

Pay not listedView role
US Veterans Health Administration workplace
Workplace photo

US Veterans Health Administration

PACU Registered Nurse

Charleston, South Carolina 29401

$68k–$138k/yrView role
MUSC Health photo
Employer photoHealth system employer

Registered Nurse II- 9C Shorty Stay

Charleston, South Carolina

Pay not listedView role
MUSC Children's Health photo
Employer photo

Registered Nurse II - Peds Heart Center

Charleston, South Carolina

Rotating shift

Pay not listedView role
U.S. Department of Veterans Affairs workplace
Employer photoHiring organization

Registered Nurse - Outpatient Specialty Care

Charleston, South Carolina

$68k–$138k/yrView role
State of South Carolina workplace
Employer photoHiring organization

Registered Nurse - Med/Surg: $2310/Week

Charleston, South Carolina

Travel contract · Night shift

$2,700/wkView role
Oak Street Health workplace
Workplace photo
Oak Street Health logo

Oak Street Health

Registered Nurse

Charleston, South Carolina 29401

$54k–$117k/yrView role

Wellmore of Daniel Island

Resident Care Coordinator RN (Skilled Nursing)

Charleston, South Carolina 29492

Pay not listedView role

Veterans Health Administration

Registered Nurse - Implant Coordinator

Charleston, South Carolina

Pay not listedView role
TNAA Healthcare logo

TNAA Healthcare

Staffing partner

RN Wound

Charleston, South Carolina

Pay not listedView role
Aya Healthcare logo

Aya Healthcare

Staffing partner

Per Diem ICU RN (PRN) - Charleston, SC

Charleston, South Carolina

$54/hrView role
MUSC photo
Employer photo

Registered Nurse I (Fall2026 New Grad Blitz) - ART Acute Care & Surgical Acute Care

Charleston, South Carolina

Pay not listedView role
MUSC Health logo

MUSC Health

Registered Nurse II - Main Sedation/PACU

Charleston, South Carolina

Pay not listedView role

Veterans Health Administration

PACU Registered Nurse

Charleston, South Carolina

Pay not listedView role
TNAA Healthcare logo

TNAA Healthcare

Staffing partner

Operating Room RN

Charleston, South Carolina

$1,839/wkView role

MUSC

Registered Nurse I (Fall 2026 New Grad Blitz) - ART Specialty ER/Chest Pain Center

Charleston, South Carolina

Pay not listedView role
MUSC Health logo

MUSC Health

Registered Nurse - Admit Transfer Center

Charleston, South Carolina

Day shift

Pay not listedView role

Veterans Health Administration

Registered Nurse - Assistant Chief Nurse (Patient Care Services)

Charleston, South Carolina

Pay not listedView role
TNAA Healthcare logo

TNAA Healthcare

Staffing partner

RN PICU

Charleston, South Carolina

Travel contract

$1,625/wkView role

MUSC

Registered Nurse I (Fall 2026 New Grad Blitz) - Institute of Psychiatry: Adult Inpatient

Charleston, South Carolina

Pay not listedView role

Veterans Health Administration

Registered Nurse - Outpatient Specialty Care

Charleston, South Carolina

Pay not listedView role
TNAA Healthcare logo

TNAA Healthcare

Staffing partner

RN Clinic

Charleston, South Carolina

Travel contract

$1,691/wkView role
MUSC workplace
Workplace photo

MUSC

Registered Nurse I (Fall 2026 New Grad Blitz) - Main Neuroscience Stepdown and Acute Care

Charleston, South Carolina

Pay not listedView role

Veterans Health Administration

Registered Nurse

Charleston, South Carolina

Pay not listedView role

MUSC

Registered Nurse I (Fall 2026 New Grad Blitz) - Institute of Psychiatry: 1N Acute Care Unit (ACU)

Charleston, South Carolina

Pay not listedView role

MUSC

Registered Nurse I (Fall 2026 New Grad Blitz) - Orthopedics and Trauma/Spine

Charleston, South Carolina

Pay not listedView role

MUSC

Registered Nurse I (Fall 2026 New Grad Blitz) - Adult Intensive Care Units (ICUs)

Charleston, South Carolina

Pay not listedView role

Other cities

Nursing jobs in Charleston, SC — 28 open | Nursing Mastery