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Nursing Mastery

100 nursing jobs in Charleston, SC

Charleston blends Southern charm with coastal living, where historic architecture and horse-drawn carriages line cobblestone streets. Nurses drawn to warm weather and beach access will find a growing healthcare corridor anchored by the Medical University of South Carolina. The city's food scene and nearby barrier islands make off-duty hours feel like a permanent vacation.

Pay and living in Charleston

Also hiring: Charleston, WV (12)

Map showing the location of Charleston, SC
Charleston, SC on the map · © Mapbox © OpenStreetMap· Open the live map
MUSC Health Charleston workplace
MUSC Health Charleston — a workplace named in a current Charleston postingView MUSC Health Charleston →

Find a nursing job in Charleston

Filter these on the boardView on the map
Operating Room · 16ICU / Critical Care · 9Med Surg · 9Psychiatric / Behavioral Health · 8Oncology · 7Emergency · 6Telemetry · 4Travel Nursing · 4

Hiring here: MUSC Health (24) · MUSC (12) · Roper St. Francis Healthcare (10) · Veterans Health Administration (10) · MUSC (5) · TNAA Healthcare (4)

RN

$52/hr

MUSC Health Charleston

Charleston, SC

  • RN
  • 12-hour nights
  • Travel contract
Apply
MUSC Health workplace

UNIV - Registered Nurse III - Department of SCTR

MUSC Health logoMUSC Health

Charleston, SC · Posted 6 days ago

  • RN
Apply
A photo of HCA Healthcare Trident Hospital

RN Admission-Discharge

HCA Healthcare Trident Hospital logoHCA Healthcare Trident Hospital

Charleston, SC · Seen active last week

  • New grads welcomed
  • RN
  • Day shift
Apply
MUSC workplace

Labor & Delivery Registered Nurse II

MUSC

Charleston, SC

  • RN
Apply
A photo of MUSC Children's Health

Registered Nurse II-Health

MUSC Children's Health

Charleston, SC

  • RN
  • Rotating shift
  • Compact license OK
Apply
A photo of Wellmore of Daniel Island

Resident Care Coordinator RN (Skilled Nursing)

Wellmore of Daniel Island logoWellmore of Daniel Island

Charleston, SC

  • RN
Apply
National HealthCare Corporation (NHC) workplace

Registered Nurse - Night Shift

National HealthCare Corporation (NHC) logoNational HealthCare Corporation (NHC)

Charleston, SC

  • RN
  • Night shift
  • Tuition reimbursement
Apply
Roper St. Francis Healthcare workplace

Registered Nurse (RN) - Licensed Practical Nurse (LPN) - Medical Assistant Certified (CMA) - Oncology - West Ashley Cancer Center

Roper St. Francis Healthcare logoRoper St. Francis Healthcare

Charleston, SC · Posted last week

  • RN
  • 8-hour days
  • Compact license OK
Apply

Registered Nurse II-Health

MUSC Health logoMUSC Health

Charleston, SC · Posted last week

  • RN
  • Rotating shift
  • Compact license OK
Apply
A photo of HCA Healthcare Trident Hospital

Cardiac EP Technologist

HCA Healthcare Trident Hospital logoHCA Healthcare Trident Hospital

Charleston, SC

  • New grads welcomed
  • Day shift
Apply
A photo of MUSC

Registered Nurse I (Fall 2026 New Grad Blitz) - Adult Intensive Care Units (ICUs)

MUSC

Charleston, SC

  • RN
Apply

Registered Nurse II - Peds Heart Center

MUSC Children's Health

Charleston, SC

  • RN
  • Rotating shift
  • Compact license OK
Apply

Registered Nurse - Day Shift

National HealthCare Corporation (NHC) logoNational HealthCare Corporation (NHC)

Charleston, SC

  • RN
  • Day shift
  • Tuition reimbursement
Apply

Nurse Manager -GI/GU Lab

$58/hr

Veterans Health Administration · Health system employer

Charleston, SC

  • RN
  • Day shift
  • Travel contract
Apply

Registered Nurse

$41/hr

Oak Street Health logoOak Street Health

Charleston, SC

  • RN
Apply

Registered Nurse (RN) | Case Management - Contract - Days

$47/hr

HealthTrust Workforce Solutions logoHealthTrust Workforce Solutions

Charleston, SC · Posted 2 weeks ago

  • RN
  • Day shift
  • Travel contract
Apply

Licensed Practical Nurse (LPN)

$28/hr

OneWell Health Care logoOneWell Health Care

Charleston, SC

  • LPN
Apply

Practical Nurse (Outpatient)

$23/hr

Military Treatment Facilities under DHA

Charleston, SC

  • RN
Apply

Registered Nurse - Med/Surg: $2310/Week

From $2,700/week

State of South Carolina

Charleston, SC

  • RN
  • Night shift
  • Travel contract
Apply

Registered Nurse - Hiring Now!

Health Care Administrators Association® (HCAA)

Charleston, SC

  • RN
  • 10-hour days
  • Compact license OK
Apply

Registered Nurse

Restore Hyper Wellness logoRestore Hyper Wellness

Charleston, SC · Posted last week

  • RN
Apply

Pre Op PACU RN

United Surgical Partners International, Inc logoUnited Surgical Partners International, Inc

Charleston, SC

  • RN
  • Rotating shift
Apply

Registered Nurse

DaVita Kidney Care logoDaVita Kidney Care

Charleston, SC

  • RN
  • 8-hour days
  • ADN accepted
Apply

Registered Nurse - Full Time

Cherry Hill Free Clinic logoCherry Hill Free Clinic

Charleston, SC

  • RN
Apply

Registered Nurse Outpatient

Novant Health logoNovant Health

Charleston, SC

  • RN
Apply

Registered Nurse

The Judge Group logoThe Judge Group

Charleston, SC

  • Magnet-designated
  • RN
  • 12-hour days
  • Travel contract
Apply

Registered Nurse - OVERNIGHT

$38/hr

Ashley River Healthcare

Charleston, SC · Posted last week

  • RN
  • 7pm-7am
  • Tuition reimbursement
Apply

Registered Nurse Case Manager

$37/hr

Insight Global

Charleston, SC

  • RN
  • 10-hour days
  • Local contract
Apply

Part - Time Lab Tutor, NURS RN - FY 2027

$28/hr

College of Southern Nevada

Charleston, SC

  • New grads welcomed · reported
  • RN
  • Evening shift
Apply

Adult Mental Health Nurse - RN

HCA Healthcare Live Oak Mental Health and Wellness

Charleston, SC · Posted last week

  • RN
  • ADN accepted
  • Tuition reimbursement
Apply

Registered Nurse

US Eye

Charleston, SC · Posted last week

  • RN
  • CEU allowance
Apply

Clinical Care Coordinator

MUSC

Charleston, SC

  • RN
  • Compact license OK
Apply

Charge Nurse - Oncology - Roper Hospital

Roper St. Francis Healthcare

Charleston, SC

  • RN
  • Weekend shift
  • Compact license OK
Apply

Registered Nurse

Center For Sight

Charleston, SC · Seen active last week

  • RN
  • CEU allowance
Apply

Registered Nurse

Bristol Hospice logoBristol Hospice

Charleston, SC

  • RN
  • ADN accepted
Apply

RN Wound

$2,220/week

TNAA Healthcare logoTNAA Healthcare · Staffing partner

Charleston, SC

  • RN
  • Day shift
  • Travel contract
Apply

CVOR RN

$2,370/week

Fusion Medical Staffing · Staffing partner

Charleston, SC

  • RN
  • Travel contract
  • CEU allowance
Apply

Registered Nurse (RN) - Wound/Ostomy

Up to $1,758/week

ATC Healthcare Services of Georgia logoATC Healthcare Services of Georgia · Staffing partner

Charleston, SC · Posted last week

  • RN
  • 8-hour days
  • Travel contract
Apply

Per Diem ICU RN (PRN) - Charleston, SC

$54/hr

Aya Healthcare logoAya Healthcare · Staffing partner

Charleston, SC

  • RN
  • 12-hour rotating
  • Per diem
Apply

Registered Nurse - Assistant Chief Nurse (Patient Care Services)

$65/hr

Veterans Health Administration

Charleston, SC

  • RN
Apply

Registered Nurse (RN) | Cardiovascular Operating Room (CVOR) - Contract - Days

$56/hr

HealthTrust Workforce Solutions logoHealthTrust Workforce Solutions

Charleston, SC

  • RN
  • Day shift
  • Travel contract
Apply

Registered Nurse- Emergency Department

Novant Health

Charleston, SC

  • RN
  • 12-hour rotating
  • Per diem
Apply

Registered Nurse II - ART 7E Oncology

MUSC

Charleston, SC

  • RN
  • 12-hour rotating
  • Compact license OK
Apply

Operating Room RN

$1,840/week

TNAA Healthcare logoTNAA Healthcare · Staffing partner

Charleston, SC

  • RN
  • Day shift
  • Travel contract
Apply

Nurse Practitioner (Hematology/Oncology)

$71/hr

Veterans Health Administration · Health system employer

Charleston, SC · Posted last week

  • New grads welcomed
  • NP
  • Day shift
Apply

RN PICU

$1,630/week

TNAA Healthcare logoTNAA Healthcare · Staffing partner

Charleston, SC

  • RN
  • Travel contract
Apply

Registered Nurse - Implant Coordinator

$49/hr

Veterans Health Administration

Charleston, SC

  • RN
  • ADN accepted
Apply

Nurse (RN Staff Outpatient MH)

$50/hr

Veterans Health Administration · Health system employer

Charleston, SC

  • RN
  • ADN accepted
Apply
See all 100 in Charleston on the board

Working and living in Charleston

· 100 open roles in this snapshot

Posted hourly pay

RN
$47/hr median
$36–$53/hr middle half · 7 postings

See roles with listed pay

Living costs

Metro price level
101.0 (100 = national)
BEA 2024
Median gross rent
$1,722/mo
Rent and tenant-paid utilities
Median household income
$92,414/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

12 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

6 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • NP1
  • RN96
  • LPN1

One posting may accept more than one credential.

Shifts listed

  • Days29
  • Rotating20
  • Nights6
  • weekend2
  • Evenings1
  • per-diem1

Postings may list several shifts or leave the shift unspecified.

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