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143 nursing jobs in FLORENCE, SC

Anchoring South Carolina's Pee Dee region, Florence pairs major regional medical campuses like McLeod and MUSC with a cost of living about 13% below the national average. Off-shift, trade hospital corridors for Dargan Street’s revitalized downtown, quiet historic neighborhoods shaded by live oaks, and easy hour-long weekend drives straight to the Atlantic coast.

Also hiring: FLORENCE, AL (55) · FLORENCE, KY (11)

FLORENCE, SC on the map· Open the live map
MUSC workplace
MUSC — a workplace named in a current FLORENCE postingView MUSC →

Find a nursing job in FLORENCE

Hiring here: McLeod Health (114) · MUSC Health (5) · Regency Hospital - Florence (5) · ATC Healthcare Services of Georgia (3) · Adoration Health (2) · Centerwell (2)

MUSC

Florence, SC

  • RN
  • Night shift
  • Compact license OK

MUSC

Florence, SC

  • RN
  • Per diem
  • Compact license OK
MUSC Health Florence logo

MUSC Health Florence

Florence, SC

  • RN
  • 12-⁠hour nights
  • Travel contract

Regency Hospital - Florence

Florence, SC

  • Sign-on bonus
  • RN
  • Night shift
  • New grads welcomed
McLeod Health logo

McLeod Health

Florence, SC

  • NP
  • Day shift
MUSC Health logo

MUSC Health

Florence, SC · Health system employer

  • RN
  • Monday - Friday day shift; no call
  • Compact license OK
Eye Health America logo

Eye Health America

Florence, SC

  • RN
  • Compact license OK
Medical Services of America logo

Medical Services of America

Florence, SC

  • RN
  • Rotating shift
Eye Health America LLC logo

Eye Health America LLC

Florence, SC

  • RN
  • Per diem
  • Compact license OK
Amedisys logo

Amedisys

Florence, SC

  • LPN
  • Day shift

Fusion Medical Staffing

Florence, SC · Staffing partner

  • CRNA
  • Travel contract
  • CEU allowance
ATC Healthcare Services of Georgia logo

ATC Healthcare Services of Georgia

Florence, SC · Staffing partner

  • RN
  • 12-⁠hour nights
  • Travel contract

Regency Hospital - Florence

Florence, SC

Registered Nurse (RN) / Nights

Posted last week

$40–$53/hr

  • Sign-on bonus
  • RN
  • Night shift
MUSC Health logo

MUSC Health

Florence, SC · Health system employer

  • RN
  • Compact license OK
ATC Healthcare Services of Georgia logo

ATC Healthcare Services of Georgia

Florence, SC · Staffing partner

  • RN
  • 12-⁠hour nights
  • Travel contract

Regency Hospital - Florence

Florence, SC

Registered Nurse (RN) / PRN

Posted last week

$53/hr

  • Sign-on bonus
  • RN
  • 12-⁠hour nights
  • Per diem
McLeod Health logo

McLeod Health

Florence, SC

  • NP
  • Night shift
ATC Healthcare Services of Georgia logo

ATC Healthcare Services of Georgia

Florence, SC · Staffing partner

  • RN
  • 12-⁠hour nights
  • Travel contract

Regency Hospital - Florence

Florence, SC

Registered Nurse (RN) / Days

Posted last week

$40–$53/hr

  • Sign-on bonus
  • RN
  • Day shift
McLeod Health logo

McLeod Health

Florence, SC

  • RN

Regency Hospital - Florence

Florence, SC

  • RN/LPN
  • Per diem

McLeod Health

26 open roles

Nurse Practitioner - Cardiology - Day Shift

Florence, SC · Posted last week

  • New grads welcomed
  • NP
  • Day shift

CRNA/ McLeod Regional Medical Center

Florence, SC · Posted last week

  • New grads welcomed
  • CRNA
  • Day shift

Night Shift Nurse Practitioner - Intensivists

Florence, SC · Posted last week

  • New grads welcomed
  • NP
  • Night shift
  • New grads welcomed
  • NP
  • Night shift

Post Acute Quality Manager - Hospice & Home Health

Florence, SC · Posted 2 weeks ago

  • RN
  • New grads welcomed
  • NP
  • Night shift

Nurse Practitioner - Orthopedics - Florence

Florence, SC · Posted last week

  • NP

Night Shift - Nurse Practitioner - Hospitalists

Florence, SC · Posted last week

  • NP
  • Night shift

Service Excellence Manager - Service Excellence

Florence, SC · Posted last week

  • NP

Nurse Practitioner - Vascular Associates

Florence, SC · Posted last week

  • NP

Nurse Practitioner - Neuro Endovascular

Florence, SC · Posted last week

  • NP

Nurse Extern - Surgery II

Florence, SC · Posted 3 days ago

  • RN

Staff Nurse - Labor & Delivery

Florence, SC · Posted 3 days ago

  • RN
  • Rotating shift

CRNA- McLeod Loris Hospital

Florence, SC · Posted last week

  • New grads welcomed
  • CRNA
  • RN

Registered Nurse - Recovery Room - FT

Florence, SC · Posted 5 days ago

  • RN
  • Per diem

RN Staff Nurse - Day Shift - Neuro Endovascular

Florence, SC · Posted 2 weeks ago

  • Sign-on bonus
  • RN

Graduate Nurse - RN - Nephrology

Florence, SC · Posted last week

  • RN

Registered Nurse - Cardiovascular Lab - FT

Florence, SC · Posted last week

  • RN

Working and living in FLORENCE

· 143 open roles

Living costs

Metro price level
86.8 (100 = national)
BEA 2024
Median gross rent
$992/mo
Rent and tenant-paid utilities
Median household income
$56,143/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

7 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

18 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • CRNA3
  • NP11
  • RN115
  • LPN11

One posting may accept more than one credential.

Shifts listed

  • per-diem49
  • Nights31
  • Days24
  • Rotating6
  • Evenings3
  • weekend2

Postings may list several shifts or leave the shift unspecified.

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