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Nursing Mastery

99 nursing jobs in Columbia, SC

Columbia, South Carolina's capital, blends Southern charm with collegiate energy thanks to the University of South Carolina campus downtown. The Congaree River winds through the city, and the Vista district offers dining and nightlife. Nurses relocating here will find a mid-sized metro with a relaxed pace and warm weather most of the year.

Pay and living in Columbia

Also hiring: Columbia, MO (47) · Columbia, MD (14) · Columbia, TN (8)

Map showing the location of Columbia, SC
Columbia, SC on the map · © Mapbox © OpenStreetMap· Open the live map
Prisma Health Richland workplace
Prisma Health Richland — a workplace named in a current Columbia postingView Prisma Health Richland

Find a nursing job in Columbia

Hiring here: Prisma Health (36) · MUSC Health (9) · Veterans Health Administration (9) · Prisma Health (6) · ACG Hospice (2) · Azza HealthCare Agency (2)

Registered Nurse

$50/hr

Prisma Health Richland

Columbia, SC

  • RN
  • 12-hour nights
  • Travel contract
  • CMS 3-star hospital
Apply
Prisma Health workplace

Registered Nurse (RN)-Employer Health Services, FT, Day

Prisma Health logoPrisma Health

Columbia, SC · Posted 2 days ago

  • RN
Apply
MUSC Health workplace

Registered Nurse II - CSSU

MUSC Health logoMUSC Health

Columbia, SC · Posted last week

  • Sign-on bonus
  • RN
Apply
Lexington Health workplace

Office RN

Lexington Health logoLexington Health

Columbia, SC

  • Sign-on bonus
  • RN
  • Day shift
  • New grads welcomed · reported
Apply
  • RN
  • Night shift
  • Compact license OK
Apply

Registered Nurse II - Float Pool

MUSC Health logoMUSC Health

Columbia, SC · Posted 2 weeks ago

  • Sign-on bonus
  • RN
  • 12-hour rotating
  • Compact license OK
Apply

RN

Lexington Health logoLexington Health

Columbia, SC

  • Sign-on bonus
  • RN
  • Day shift
  • Agency contract
  • Magnet-designated hospital
  • New-grad residency
Apply

Primary Care Nurse Practitioner

$67/hr

Veterans Health Administration · Health system employer

Columbia, SC · Seen active last week

  • New grads welcomed
  • NP
  • Day shift
Apply

Registered Nurse (RN)

$50/hr

New Life Home Care logoNew Life Home Care

Columbia, SC

  • RN
  • Day shift
  • Per diem
Apply

Sr. Manager - Business Compliance

$64/hr

CVS Health logoCVS Health

Columbia, SC · Posted last week

  • RN
  • ADN accepted
Apply

Registered Nurse

$33.00–$45.00

Encompass Health logoEncompass Health

Columbia, SC · Posted 2 weeks ago

  • Sign-on bonus
  • RN
  • Day shift
  • Tuition reimbursement
Apply

Registered Nurse

$27.22–$44.23

Innovative Renal Care logoInnovative Renal Care

Columbia, SC

  • RN
  • ADN accepted
Apply

RN Home Health

$68k–$102k/yr target

Optum logoOptum

Columbia, SC

  • RN
Apply
  • RN
Apply

Registered Nurse - RN

Aura Health logoAura Health

Columbia, SC

  • RN
Apply

Registered Nurse (RN)

ACG Hospice logoACG Hospice

Columbia, SC

  • RN
  • Tuition reimbursement
Apply

Registered Nurse - Full-Time

Azza HealthCare Agency

Columbia, SC · Posted last week

  • RN
  • Day shift
  • Tuition reimbursement
Apply

Registered Nurse - Full-Time

Plan A Health logoPlan A Health

Columbia, SC

  • RN
  • Day shift
  • Tuition reimbursement
Apply
  • RN
  • 8-hour days
  • Preceptorship program
Apply

PACU Licensed Registered Nurse (RN REQ)

$38/hr

Palmetto Surgery Center logoPalmetto Surgery Center

Columbia, SC

  • RN
  • Day shift
Apply

Full-time Pediatric RN/LPN for Infant Tracheostomy Care

$33/hr

Logistical Med & Beyond

Columbia, SC · Seen active 2 weeks ago

  • RN
Apply

Registered Nurse - Full Time 7AM - 7:30PM | 36hr/Week

$52/hr

Advanced Correctional Healthcare

Columbia, SC

  • RN
  • 12-hour days
  • Floating required
Apply

Home Health Licensed Practical Nurse

$30/hr

Centerwell logoCenterwell

Columbia, SC

  • LPN
Apply

Registered Nurse RN

$45/hr

RecSol Recovery Solutions

Columbia, SC

  • RN
  • Per diem
  • Tuition reimbursement
Apply

Registered Nurse - Gastroenterology

$54/hr

US Veterans Health Administration

Columbia, SC

  • RN
  • Day shift
  • Travel contract
  • Union represented
Apply

Registered Nurse - Homecare

$27/hr

Maxim Healthcare

Columbia, SC

  • RN
Apply

Nurse Clinician - Home IV - PRN (RN)

$40/hr

Palmetto Infusion logoPalmetto Infusion

Columbia, SC

  • RN
  • Day shift
  • Per diem
Apply

School Nurse

Legacy Traditional Schools

Columbia, SC · Posted last week

  • RN
  • Tuition reimbursement
Apply

Poison Center - Nurse

State of South Carolina

Columbia, SC · Seen active last week

  • RN
  • Day shift
  • Tuition reimbursement
  • Union represented
Apply
  • RN
  • Day shift
  • Travel contract
Apply

Outpatient Registered Nurse - RN

Fresenius Medical Care

Columbia, SC · Seen active 2 days ago

  • RN
Apply

Registered Nurse - PCU

MUSC

Columbia, SC

  • Sign-on bonus
  • RN
  • Rotating shift
  • Compact license OK
Apply

Registered Nurse

CNSCares

Columbia, SC

  • RN
  • Night shift
  • Agency contract
Apply

PRN Supervisory Visits RN

Addus Homecare

Columbia, SC

  • RN
  • Per diem
Apply

Emergency RN

$1,630/week

TNAA Healthcare logoTNAA Healthcare · Staffing partner

Columbia, SC

  • RN
  • Day shift
  • Travel contract
Apply
  • RN
  • Day shift
  • Travel contract
Apply

Registered Nurse (RN) - Step-Down

Up to $2,051/week

ATC Healthcare Services of Georgia logoATC Healthcare Services of Georgia · Staffing partner

Columbia, SC · Posted last week

  • RN
  • Ratio 1:4
  • 12-hour nights
Apply

RN/LPN – $38-45/hr Weekly Pay 36 hrs Guaranteed - 13 week contract

$38/hr

Zentech Consulting logoZentech Consulting · Staffing partner

Columbia, SC

  • RN
  • Day shift
  • Per diem
Apply

Registered Nurse - Assistant Nurse Manager Gastroenterology

$58/hr

Veterans Health Administration · Health system employer

Columbia, SC

  • RN
Apply

Manager, Practice Transformation

$51/hr

CVS Health logoCVS Health

Columbia, SC

  • RN
Apply

Pediatric Registered Nurse (RN)

ACG Hospice logoACG Hospice

Columbia, SC

  • RN
  • ADN accepted
  • Tuition reimbursement
Apply

Registered Nurse - Hiring Now

Azza HealthCare Agency

Columbia, SC

  • RN
  • Tuition reimbursement
Apply

Registered Nurse Navigator

PruittHealth

Columbia, SC

  • RN
  • Day shift
  • Preceptorship program
Apply

1st Shift Registered Nurse (RN): OIDD - Midlands

State of South Carolina

Columbia, SC

  • Sign-on bonus
  • RN
  • Day shift
  • +$6.25/hr differential
Apply
  • RN
  • Night shift
  • Per diem
Apply

PCU RN

$1,780/week

TNAA Healthcare logoTNAA Healthcare · Staffing partner

Columbia, SC

  • RN
  • Travel contract
Apply

School Registered Nurse | Columbia, South Carolina

Soliant logoSoliant · Staffing partner

Columbia, SC

  • RN
  • Agency contract
Apply

Licensed Practical Nurse

$19/hr

Veterans Health Administration · Health system employer

Columbia, SC

  • LPN
Apply

Working and living in Columbia

· 99 open roles in this snapshot

Posted hourly pay

RN
$37/hr median
$32$45/hr middle half · 12 postings

See roles with listed pay

Living costs

Metro price level
93.7 (100 = national)
BEA 2024
Median gross rent
$1,204/mo
Rent and tenant-paid utilities
Median household income
$55,529/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

11 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

2 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • NP1
  • RN94
  • LPN4

One posting may accept more than one credential.

Shifts listed

  • Days50
  • Nights18
  • Rotating6
  • per-diem3

Postings may list several shifts or leave the shift unspecified.

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