99 nursing jobs in Columbia, MO
Anchored by MU Health Care and vibrant college energy, Columbia pairs academic medicine with easy Midwest living. Unwind after shifts along the shaded MKT Nature Trail or grab local coffee in The District. Your paycheck stretches comfortably here, with a cost of living nearly 11% below the national average.
Also hiring: Columbia, SC (459) · Columbia, MD (80) · Columbia, TN (21)
Find a nursing job in Columbia
Hiring here: Veterans Health Administration (31) · University of Missouri Health Care (12) · CenterPointe Hospital Columbia (8) · Compassus (6) · BBH Burrell Behavioral Health (5) · ACG Hospice (2)
- Sign-on bonus
- RN
- 12-hour shifts
- New grads welcomed
- RN
- 8-hour days
- Per diem
RN: Staff Nurse II – Children’s Cancer and Blood Disorders Unit – Full Time
Columbia, MO · Posted last week
$34–$51/hr
- RN
- 10-hour days
- Compact license OK
Sedation RN - PRN
Columbia, MO
- RN
- Tuesdays and/or Wednesdays | Daytime Hours
- Per diem
- RN
- Day shift
Hospital based Advanced Practice Registered Nurse
Columbia, MO
$100,000–$120,000/year
- APRN
- Day shift
Nurse Clinician
$75,000–$90,000/year
- RN
- Day shift
- Compact license OK
- RN
- Day shift
- Compact license OK
- RN
- Night shift
- Sign-on bonus
- RN
- Night shift
- Compact license OK
- New grads welcomed
- RN
- 12-hour shifts
- Per diem
- Sign-on bonus
- LPN
- Monday – Friday, days, 40 hours a week
- Compact license OK
- Sign-on bonus
- RN
- Weekend Days (Sat & Sun only and 1 other shift every other week)
- Compact license OK
- Sign-on bonus
- RN
- 12-hour nights
- New grads welcomed
- RN
- 12-hour days
- Compact license OK
Licensed Practical Nurse (LPN)
Posted last week
- Sign-on bonus
- LPN/LVN
- Night shift
RN: Family Medicine - Days
$34–$51/hr
- RN
- 12-hour days
- Compact license OK

University of Missouri Health Care
3 open roles · day & weekend shifts · Permanent
University of Missouri Health Care
3 open roles · day & weekend shifts · Permanent
- RN
- Day shift
- Compact license OK
- RN
- 12-hour weekends only
- Compact license OK
- RN
- 12-hour weekends only
- Compact license OK
- Sign-on bonus
- RN
- 7:00 a.m. to 7:30 p.m.
- Orthopedic Inpatient Unit
- Sign-on bonus
- RN/LPN
- Night shift
- RN
- Day shift
- Travel contract
Hospital based Advanced Practice Registered Nurse
$100,000–$120,000/year
- APRN
- Day shift
- Sign-on bonus
- RN
- Day shift
- New grads welcomed
Local/Travel Registered Nurse PCU/Stepdown - $65/hr (Quick Offer)
$2,340–$2,515/week
- RN
- Ratio 1:3
- 12-hour nights
Licensed Practical Nurse (LPN)
$27–$30/hr
- LPN
- 1 FT Days M-F, PRN Evenings, Nights, and Weekends
- Tuition reimbursement
LPN: Neuroscience - Days
$23–$36/hr
- LPN
- Three – 12’s – Days – Rotating Holidays, Every other weekend
- Neuroscience Unit
RN Med Surg ($71/hr)
$65–$71/hr
- RN
- 1900-0730
- Medical-Surgical (Med Surg) (Oncology/Neuro)
Registered School Nurse Hannibal, MO
$42–$45/hr
- RN
- Agency contract
- RN
- 12-hour nights
- Travel contract
Psychiatric Nurse Practitioner
Posted last week
- NP
- Rotating shift
Working and living in Columbia
· 99 open roles
Posted hourly pay
- RN
- $34/hr median
- $33–$46/hr middle half · 20 postings
- LPN
- $24/hr median
- $23–$25/hr middle half · 6 postings
Living costs
- Median gross rent
- $1,097/mo
- Rent and tenant-paid utilities
- Median household income
- $66,498/yr
- All local households, not nurse pay
New to our board this week
4 current postings first appeared here in the past seven days.
Credentials accepted
- NP1
- APRN2
- RN77
- LPN15
- LVN4
- CNA3
One posting may accept more than one credential.
Shifts listed
- Days35
- Nights20
- Rotating6
- per-diem6
- weekend4
- Evenings1
Postings may list several shifts or leave the shift unspecified.
Living in Columbia
Columbia, Missouri is a mid-state college town of roughly 128,000–132,000 where MU Health and Boone Hospital sit inside a city you can often cross in about 15 minutes.
More about life hereShow less
Nurses frequently choose Benton-Stephens, a historic pocket north of downtown next to campus and two hospitals, or walkable Old Southwest between Broadway and Stadium, with bungalows and the MKT Trail. Southwest Thornbrook offers newer homes, a pool, and highly rated schools from about $350,000–$550,000; citywide medians sit in the low-to-mid $300s, with some entries under $200,000 and median rent near $925. Downtown's 50-block CID—Flat Branch, North Village Arts District, Avenue of the Columns—puts coffee and Pressed rooftop bar within a few blocks, while True/False, Roots N Blues, and a year-round farmers market (vendors within 50 miles) fill the calendar.
More than 70 parks, 50-plus trail miles, Rock Bridge caves, and the Katy Trail's 237 miles define outdoor life; I-70 reaches St. Louis or Kansas City in two hours. Tradeoffs include a median age of 29, cooled new construction, and small-city limits—offset by short specialist waits at ranked hospitals and an approachable, lower-cost metro.
Sources
Neighborhoods
Nurses and other healthcare workers often land in Benton-Stephens, just north of downtown, because it is bordered by the University of Missouri campus and two major hospitals and draws graduate students and young professionals who want historic, walkable streets. Old Southwest, south of downtown between Broadway and Stadium Boulevard, is the city's most iconic neighborhood: tree-canopied blocks of craftsman bungalows, Tudor revival, colonial, and mid-century ranch homes, with Hickman High School, the MKT Trail, John A. Stewart Park, and Albert-Oakland Park close by, and prices typically from the upper $200s to $500,000 or more.
Thornbrook, a southwest planned community of more than 500 homes with a pool, walking trails, pavilion, and HOA, runs about $350,000 to well over $550,000 and is aimed at buyers who want newer construction, highly rated schools, and quicker access to shopping, dining, and medical facilities without central congestion. Locals also steer newcomers toward central Columbia in or a few blocks off the Stadium/Broadway/Providence loop, while downtown's 50-block Community Improvement District includes walkable pockets such as Flat Branch, the North Village Arts District, The Strollway, West End, Government District, and Avenue of the Columns; housing exists north, south, east, and west of I-70, not only south.
Housing
Early 2026 reporting puts Columbia's median home price between $302,000 and $350,000; a mid-2025 snapshot had median sale prices near $305,000, about 5% above the prior year, while U.S. News lists a median home value of $281,958 against a national average of $359,870 and median rent of $925. Established neighborhoods still offer some entries below $200,000; premium subdivisions regularly clear $500,000. Old Southwest smaller bungalows start in the upper $200s and renovated larger homes exceed $500,000 and tend to sell within weeks; Thornbrook spans about $350,000 to over $550,000 for custom lots. New-construction permits cooled in late 2024, so resale listings dominate, occupancy is described as very high, and the market is called healthy if no longer in a rush.
Getting around
Typical drives are short: U.S. News puts the average commute at about 14.34 minutes, and local write-ups treat fifteen minutes from the northwest corner to the university quad as a long trip, with cross-town drives often finished before a second song ends outside rush hour. Benton-Stephens is walkable to campus and two major hospitals, which is why healthcare workers concentrate there; Thornbrook on the southwest side is described as having quick access to medical facilities without the traffic of more central areas.
Old Southwest residents can use the MKT Trail along the southern edge as a car-free route toward downtown. I-70 reaches Kansas City or St. Louis in about two hours; named bus lines and hospital parking conditions are not detailed in these sources.
Food and dining
Downtown's Community Improvement District is a live/work/play grid where a coffee shop is never more than a block or two away, and Pressed, a rooftop bar with high-end drinks, appetizers, and desserts, caps the Class A office tower beside the Boone County Courthouse, with Hawthorne Bank on the ground floor. The Columbia Farmer's Market is year-round and sheltered, with a rule that every vendor must come from within 50 miles, so produce and prepared food stay local.
Visit Columbia frames CoMo dining as ranging from down-home to around the world, with a separate bars-and-nightlife scene from casual pints to dance floors; nearby Rocheport is repeatedly recommended for great food and antiques. Specific late-night restaurants on hospital campuses are not named in these sources.
Outdoors
Columbia lists more than 70 parks and more than 50 miles of trails. The MKT Trail runs along Old Southwest's southern edge into downtown; the Katy Trail clips the city's south edge and connects riders to 237 miles of river-valley scenery.
Rock Bridge Memorial State Park supplies caves, boardwalks, and limestone bluffs that feel far from town, while John A. Stewart Park and Albert-Oakland Park sit within walking distance of Old Southwest. Parks and Recreation also hosts Neighborhood Park Fun Days to get neighbors outside together.
Arts and culture
Annual anchors include True/False Film Fest, Roots N Blues, and the craft-beer Winter Session, all locally grown and volunteer-heavy. Downtown's North Village Arts District, Flat Branch (a former rail yard now mixed with offices, apartments, restaurants, and a newer park), Avenue of the Columns, The Strollway, and West End sit inside a 50-square-block Community Improvement District with colleges, historic neighborhoods, about 300 residences, and 600 businesses.
University of Missouri, Columbia College, and Stephens College feed lectures, research, library programming, and Tiger game days when white coats mix with hoodies; alley murals and local-radio indie bills fill the gaps. Rocheport's antique-store old town and the Boone County Historical Center—plus the park behind it—are the usual nearby culture day trips.
For families
Old Southwest attracts families for walkability, Hickman High School inside the neighborhood, several well-regarded elementary schools, the MKT Trail, and nearby parks. Thornbrook is zoned for some of the city's highest-rated schools and layers a community pool, trails, pavilion, and HOA events onto newer houses.
Columbia Public Schools offer a hands-on aerospace engineering track for high-schoolers and dual-credit art history, and the city is repeatedly billed as having top-rated public schools feeding off three colleges. Neighborhood officers are assigned to areas to visit schools and events; the median age of 29.0 means family blocks sit next to a large student population, and livability write-ups flag healthcare and cost of living as strengths.
What locals say
Residents call Columbia cheaper than St. Louis, an easy two-hour shot to Kansas City or St. Louis, and more progressive and activity-rich than much of middle Missouri, with a strong sense of community plus trails, parks, and restaurants. People are described as approachable—neighbors wave, cashiers chat, and a cafe barista might be a PhD candidate who still remembers your order—while culture shows up as backyard bluegrass, downtown murals, and indie bands rather than a staged scene.
Central Columbia around the Stadium/Broadway/Providence loop is a frequent neighborhood recommendation. The shine rubs off in slower in-migration after the 2021–22 remote-work rush, cooled new-construction permits, and a city that still feels small next to true metros even as housing has climbed.
