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MUSC Health

Health system in Charleston, SC

  • Sign-on bonus up to $30,000 on 8+ roles
  • Hiring rotating and days
  • New grads welcome on 4+ roles
See 61 open roles
MUSC Health photo

From 61 postings and nurse reviews · Employer research Oct 9, 2026Sources

The short version

  1. Nurses and department colleagues are described over and over as kind, supportive, and willing to teach each other, which is the thing most reviewers name first.

  2. You will chart in Epic, named in the postings we carry.

    For travel nurses
    Sources
    From employer postings
  3. A Glassdoor estimate puts Registered Nurse II on ART 7W Bone Marrow Transplant in Charleston at $70K–$90K a year; that is the job board's estimate, not pay stated by MUSC Health.

    For experienced nurses
    Sources

Who it fits

Best fit

  • New grads: 4 of the 48 roles on this page welcome new grads

Nursing here

Charting system

Epic

From employer postings

What nurses say

Themes from public reviews

Summaries of published reviews, with the original sources.

Coworker Camaraderie
Nursing and department colleagues are widely described as kind, compassionate, supportive, and willing to teach one another.
Sources
Compensation vs Cost of Living
Staff express frustration that base wages do not keep pace with the high cost of living in the Charleston area, and cite expensive employee parking.
Sources
Staffing Shortages
Reviews across multiple campuses, including regional facilities and main ERs, note frequent short staffing and heavy patient censuses.
Sources
More review themes
Facility Age and Equipment Quality
A downtown Charleston bedside nurse cited dated main hospital facilities and cost-cutting on clinical supplies and sterile processing.
Sources
As of 2026-08-13Source: glassdoor.com

The hard parts

What to ask

  • How is base pay set for the role, and which differentials apply?
  • Which shifts are open, and what are the weekend, holiday and call rules?
  • How long is orientation, and will I have one preceptor?
  • What is the usual patient load, and how often do nurses float?
  • Which hospital or site, and which unit, would I work on?

Common questions

Does MUSC Health hire new grads?

4 of the 48 roles on this page welcome new grads.

Is there a sign-on bonus?

Yes, on 8 of the 48 roles on this page, up to $30,000.

Which shifts are open?

Of the 36 roles with a stated shift on this page, 23 are rotating shifts, 10 are day shifts and 3 are night shifts.

Which units are hiring?

ER (5), med surg (4), PACU (3), psych (3) and more.

How do I apply?

Choose a role and press Apply. Your application comes to our team, we send it to MUSC Health, and we tell you what happens next.

Roles from MUSC Health

MUSC Health logo

MUSC Health

Orangeburg, SC · Health system employer

Registered Nurse 3 West

Posted 3 days ago

  • RN
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • New grads welcomed
  • RN
  • 3 - 12 Hour rotating shifts per week, including some weekends
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • 3 - 12 Hour Rotating Shifts per week, including some weekends
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • New grads welcomed
  • RN
  • Ratio 1:3–1:4
  • 3-12 hour shifts. Shifts vary based on the needs of the department.
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • 12-⁠hour shifts
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • Rotating shift
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • 12-⁠hour rotating
  • 10 East
MUSC Health logo

MUSC Health

Columbia, SC · Health system employer

  • Sign-on bonus
  • RN
  • Rotating shift
  • 6T CSSU
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • Rotating shift
  • SCTR Nexus Clinical Research Unit
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • Rotating shift
  • 6West Burn Stepdown Unit
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • Magnet-designated
  • RN
  • Rotating shift
  • SMICU (Specialty Medical) 5E (Main)
MUSC Health logo

MUSC Health

Florence, SC · Health system employer

  • RN
  • Monday - Friday day shift; no call
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • Rotating shift
  • MedSurg 7E (Main)
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • Rotating shift
  • MICU (Medical ICU) (Main)
MUSC Health logo

MUSC Health

Columbia, SC · Health system employer

  • Sign-on bonus
  • RN
  • 12-⁠hour rotating
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • New grads welcomed
  • RN
  • 12-⁠hour rotating
  • PACU (Post Anesthesia Care Unit) (Main)
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • 10-⁠hour days
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • 8-⁠hour days
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • 10-⁠hour days
  • Compact license OK
MUSC Health logo

MUSC Health

Florence, SC · Health system employer

  • RN
  • Compact license OK
MUSC Health logo

MUSC Health

Camden, SC · Health system employer

  • Sign-on bonus
  • RN
  • 12-⁠hour rotating
  • Compact license OK
MUSC Health logo

MUSC Health

Columbia, SC · Health system employer

  • Sign-on bonus
  • RN
  • Day shift
  • Compact license OK
MUSC Health logo

MUSC Health

Columbia, SC · Health system employer

  • RN
  • Day shift
  • Compact license OK
MUSC Health logo

MUSC Health

Columbia, SC · Health system employer

  • Sign-on bonus
  • RN
  • Rotating shift
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • 12-⁠hour nights
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • New grads welcomed
  • RN
  • 3-12 hour shifts. Shifts vary based on the needs of the department.
  • 7 West Surgical Oncology
MUSC Health logo

MUSC Health

Bluffton, SC · Health system employer

  • RN
  • Rotating shift
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • Night shift
  • Compact license OK
MUSC Health logo

MUSC Health

Mullins, SC · Health system employer

  • RN
  • Compact license OK
MUSC Health logo

MUSC Health

Columbia, SC · Health system employer

  • Sign-on bonus
  • RN
  • Compact license OK
  • ADN accepted
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • Rotating shift
  • Compact license OK
MUSC Health logo

MUSC Health

Denmark, SC · Health system employer

  • LPN
  • Night shift
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • Sign-on bonus
  • RN
  • 12-⁠hour days
  • Compact license OK
MUSC Health logo

MUSC Health

Bluffton, SC · Health system employer

  • RN
  • Compact license OK
  • ADN accepted
MUSC Health logo

MUSC Health

Columbia, SC · Health system employer

  • RN
  • Rotating shift
  • Compact license OK
MUSC Health logo

MUSC Health

Bluffton, SC · Health system employer

  • RN
  • Compact license OK
  • ADN accepted
MUSC Health logo

MUSC Health

Summerville, SC · Health system employer

  • RN
  • Compact license OK
MUSC Health logo

MUSC Health

Columbia, SC · Health system employer

  • RN
  • Day shift
  • Compact license OK
MUSC Health logo

MUSC Health

Chester, SC · Health system employer

  • RN
  • Compact license OK
MUSC Health logo

MUSC Health

Columbia, SC · Health system employer

  • RN
  • Rotating shift
  • Compact license OK
MUSC Health logo

MUSC Health

Camden, SC · Health system employer

  • Sign-on bonus
  • RN
  • Rotating shift
  • Compact license OK
MUSC Health logo

MUSC Health

Mount Pleasant, SC · Health system employer

  • RN
  • Compact license OK
  • ADN accepted
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • 8-⁠hour days
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • Rotating shift
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • Day shift
  • Compact license OK
MUSC Health logo

MUSC Health

Florence, SC · Health system employer

  • RN
  • Compact license OK
  • ADN accepted
MUSC Health logo

MUSC Health

Myrtle Beach, SC · Health system employer

  • RN
  • Compact license OK
MUSC Health logo

MUSC Health

Charleston, SC · Health system employer

  • RN
  • 12-⁠hour rotating
  • Compact license OK
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