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55 nursing jobs in Florence, AL

Florence pairs legendary musical heritage and scenic riverfront vistas with a calm, low-stress pace. With living costs about 15% below the national average, nurses can settle into historic Queen Anne homes near UNA or quiet neighborhoods by Forest Hills School, spending off-shifts strolling vibrant Court Street.

Also hiring: Florence, SC (143) · Florence, KY (11)

Florence, AL on the map· Open the live map
North Alabama Medical Center workplace
North Alabama Medical Center — a workplace named in a current Florence postingView North Alabama Medical Center →

Find a nursing job in Florence

Hiring here: North Alabama Medical Center (20) · Lifepoint Health (7) · North Alabama Medical Center (6) · Hospice of North Alabama (5) · Healthforce (3) · North Alabama Shoals Hospital (3)

North Alabama Medical Center workplace

North Alabama Medical Center

15 open roles

Patient Care Assistant (PCA), PRN - Nurse Float

Florence, AL · Posted 6 days ago

  • RN
  • Per diem

Registered Nurse (RN) Labor and Delivery

Florence, AL · Posted 6 days ago

  • RN
  • Day shift

Registered Nurse (RN) Emergency Services

Florence, AL · Posted last week

  • New grads welcomed
  • RN
  • 12-⁠hour evenings

Registered Nurse (RN) PACU

Florence, AL · Posted last week

  • New grads welcomed
  • RN

Registered Nurse (RN) ICU

Florence, AL · Posted last week

  • RN
  • Night shift
  • Per diem

Registered Nurse (RN) ICU

Florence, AL · Posted last week

  • RN
  • Night shift

Registered Nurse (RN) Surgery

Florence, AL · Posted 6 days ago

  • New grads welcomed
  • RN
  • Day shift

RN New Grad

Florence, AL · Posted last week

  • RN

Registered Nurse (RN) ICU

Florence, AL · Posted last week

  • RN
  • Night shift

Registered Nurse (RN) Emergency Services

Florence, AL · Posted last week

  • New grads welcomed
  • RN
  • Per diem

Registered Nurse (RN) PACU

Florence, AL · Posted 2 weeks ago

  • New grads welcomed
  • RN
  • Day shift

RN New Grad

Florence, AL · Posted last week

  • RN

Registered Nurse (RN) ICU

Florence, AL · Posted last week

  • RN
  • Night shift

Registered Nurse (RN) Endoscopy

Florence, AL · Posted last week

  • RN
  • 10-⁠hour days

RN New Grad

Florence, AL · Posted 2 weeks ago

  • RN
  • Per diem

Metro Infectious Disease Consultants

Florence, AL

  • RN
  • Weekend shift

North Alabama Shoals Hospital

Florence, AL

  • RN
  • Job Type: Full-Time | Day
  • ADN accepted
Hospice of North Alabama logo

Hospice of North Alabama

Florence, AL

  • RN

North Alabama Medical Center

Florence, AL

  • New grads welcomed
  • RN
  • Day shift

Question Techs Private Limited

Florence, AL

LPN – Long-Term Care (LTC)

Posted last week

$35–$38/hr

  • LPN
  • 12-⁠hour nights
  • Travel contract

SouthernCare New Beacon Hospice

Florence, AL

Registered Nurse

Posted last week

  • RN
  • Per diem

The Hirexpress LLC

Florence, AL

  • RN
  • Emergency Services
  • Tuition reimbursement

Affinity Hospice Holdings, LLC

Florence, AL

  • CNA
  • Per diem

Fairview Hospital / Cleveland Clinic

Florence, AL

  • RN
Lifepoint Health logo

Lifepoint Health

Florence, AL

  • LPN
Healthforce logo

Healthforce

Florence, AL · Staffing partner

  • LPN
  • 3x12-⁠hour nights (7:00 p.m. to 7:30 a.m.)
  • Travel contract
TNAA Healthcare logo

TNAA Healthcare

Florence, AL · Staffing partner

ICU RN

$1,888/week

  • RN
  • Day shift
  • Travel contract

North Alabama Shoals Hospital

Florence, AL

  • LPN
Hospice of North Alabama logo

Hospice of North Alabama

Florence, AL

  • RN

North Alabama Medical Center

Florence, AL

  • RN
  • Per diem
  • ADN accepted
Lifepoint Health logo

Lifepoint Health

Florence, AL

  • RN
  • 12-⁠hour nights
Healthforce logo

Healthforce

Florence, AL · Staffing partner

  • LPN
  • 7:00 PM–7:30 AM
  • Travel contract

North Alabama Shoals Hospital

Florence, AL

RN New Grad

Posted last week

  • RN
  • Full-Time | Day
  • Emergency Services
Hospice of North Alabama logo

Hospice of North Alabama

Florence, AL

  • RN
  • Day shift

North Alabama Medical Center

Florence, AL

  • RN
  • Day shift
  • ADN accepted
Lifepoint Health logo

Lifepoint Health

Florence, AL

  • RN
Healthforce logo

Healthforce

Florence, AL · Staffing partner

  • LPN
  • 12-⁠hour days
  • Travel contract
Hospice of North Alabama logo

Hospice of North Alabama

Florence, AL

  • RN
  • Day shift

North Alabama Medical Center

Florence, AL

  • RN
  • 12-⁠hour days
  • Tuition reimbursement
Lifepoint Health logo

Lifepoint Health

Florence, AL

  • New grads welcomed
  • RN
  • 12-⁠hour shifts
  • Per diem
Hospice of North Alabama logo

Hospice of North Alabama

Florence, AL

Registered Nurse Hospice

Posted last week

  • RN
  • Rotating shift
  • Per diem

North Alabama Medical Center

7 open roles · Hospital

  • RN
  • 12-⁠hour days
  • Per diem
  • RN
  • Per diem
  • ADN accepted
  • RN
  • Night shift
  • RN
  • 12-⁠hour nights
  • Tuition reimbursement
  • RN
  • Per diem
  • ADN accepted
  • New grads welcomed
  • RN
  • Rotating shift
  • Per diem
  • RN
  • Night shift
  • ADN accepted

Working and living in Florence

· 55 open roles

Living costs

Metro price level
84.8 (100 = national)
BEA 2024
Median gross rent
$820/mo
Rent and tenant-paid utilities
Median household income
$52,174/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

9 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

9 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • RN47
  • LPN7
  • LVN1
  • CNA1

One posting may accept more than one credential.

Shifts listed

  • Days19
  • per-diem14
  • Nights11
  • Rotating2
  • Evenings1
  • weekend1

Postings may list several shifts or leave the shift unspecified.

Living in Florence

Set along the bluffs of the Tennessee River in northwest Alabama, Florence serves as the cultural anchor of the four-city Shoals region.

More about life here

For relocating healthcare professionals, the city offers an appealing balance of university energy from the University of North Alabama, historic charm, and legendary musical heritage without big-city friction. Commutes across Florence and neighboring Sheffield or Muscle Shoals typically take under fifteen minutes, making shift work straightforward.

Downtime centers on Court Street's independent dining, dinner at Odette, or boating on the river, alongside landmarks like the Frank Lloyd Wright-designed Rosenbaum House and the annual W.C. Handy Music Festival. Housing ranges from restored Queen Anne properties along North Wood Avenue to quiet suburban subdivisions along College Hills.

The primary tradeoffs are muggy summer heat and regional compensation scales that trail larger metropolitan centers, but the payoff is an unhurried, community-oriented lifestyle with genuine architectural character and accessible outdoor recreation.

Sources
As of Sep 16, 2026
Neighborhoods

Downtown Florence and the blocks immediately surrounding the University of North Alabama—particularly north along North Wood Avenue and Lelia Street—are popular with professionals seeking quiet, walkable streets lined with historic homes. Further out, established residential pockets along the College Hills and Huntsville Road corridors offer quieter suburban-style living, while neighboring Shoals communities across the Tennessee River like Muscle Shoals, Sheffield, and Tuscumbia provide convenient, lower-density alternatives.

Sources
Housing

Florence offers a wide variety of housing stock, ranging from ornate Queen Anne single-family homes and historic residences subdivided into apartments near downtown and UNA, to conventional townhomes and modern apartment complexes on the city's outskirts. Rental options remain accessible along major thoroughfares such as Huntsville Road, while historic central neighborhoods carry a premium for their walkability and architectural character.

Sources
Getting around

Florence is heavily car-dependent but features exceptionally light traffic, with typical regional commutes averaging between thirteen and fifteen minutes. Shift workers traveling locally or crossing the bridges over the Tennessee River between Florence, Sheffield, and Muscle Shoals encounter straightforward surface-street driving with accessible facility parking and none of the gridlock typical of larger metros.

Sources
Food and dining

Downtown Court Street anchors the local dining scene with independent spots and cocktail bars, including the acclaimed farm-to-table restaurant Odette. Along the river, the rotating 360 Grille at the Marriott Shoals hotel offers fine dining paired with panoramic views of the water and the surrounding Shoals landscape.

Sources
Outdoors

Outdoor recreation is defined by the Tennessee River, which carves limestone bluffs and supports year-round boating, paddling, and bass fishing. The area features waterfront walking trails, scenic overlooks, and easy access to the nearby Natchez Trace Parkway corridor for hiking and cycling.

Sources
Arts and culture

As the birthplace of W.C. Handy, the city celebrates its blues legacy every summer with the W.C. Handy Music Festival and shares a deep recording history tied to nearby FAME Studios and Muscle Shoals Sound Studio. Architectural and historic landmarks include the Frank Lloyd Wright-designed Rosenbaum House, the ancient Florence Indian Mound, and Pope's Tavern Museum.

Sources
Seasons and weather

Florence experiences a four-season humid subtropical climate marked by long, hot, and humid summers and relatively mild winters that bring only occasional light snowfall. Precipitation is steady year-round, averaging roughly 55 inches of annual rainfall, while spring and autumn bring comfortable, temperate transitions.

Sources
For families

Families gravitate toward walkable central neighborhoods and quiet suburban enclaves near well-regarded local public schools, such as Forest Hills School and Weeden Elementary School. Downtown's Court Street provides pedestrian-friendly family outings, supplemented by community parks and local institutions like the Children's Museum of the Shoals.

Sources
What locals say

Residents praise Florence for its scenic riverfront views, rich musical heritage, down-to-earth neighbors, and manageable pace of life that avoids big-city stress. The primary tradeoffs cited by locals are regional pay scales that lag behind major metropolitan markets and intense summer humidity.

Sources

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