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Registered Nurse (RN) - Acute Care, Pediatrics, PRN, Night

Prisma Health

Seneca, South Carolina

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RNAcute CarePediatrics

Posted Aug 3, 2026 · Last seen active Aug 4, 2026

What this might mean for you

Prisma Health is an academic medical center — teaching floors, residents in the halls, and more sub-specialties to grow into. Per-diem means you set the rhythm — pick up when it works, step back when it doesn't.

What the posting states

Weekends, holidays, call
Call required

About this role

Show full description
Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, SC DPH, CMS). Provides care within the scope of the Nurse Practice Act. The acute inpatient setting may require staff to be scheduled for a weekend, holiday, and on-call work.

Skills for this role

Patient CareMedication Administration

Requirements

  • Associate degree in Nursing (Bachelor's degree in Nursing preferred)
  • One (1) year experience as a registered nurse
  • Current RN compact/multistate license recognized by the NCSBN Compact State or licensed to practice as an RN in the state the team member is working
  • Acute care experience
  • Inpatient experience
  • Working with pediatric populations
  • Night shift, weekends as needed, on call

About the employer

Prisma Health logo
Prisma Health
Academic Medical Center

Prisma Health is a large South Carolina-based healthcare system with nearly 32,000 team members, serving communities across the state including its Columbia market. The organization describes itself as being on a journey to transform the healthcare experience for patients and…

2.4 Google rating

What reviewers appreciate

  • Large health system with approximately 32,000 team members, offering diverse nursing career paths and settings
  • Remote nursing positions available for South Carolina residents, including post-discharge outreach roles
  • Strong stated commitment to diversity, inclusion, and valuing different backgrounds and lived experiences

What reviewers flag

  • Extensive compliance and policy requirements may create administrative burden for nursing staff
  • Large organizational size of nearly 32,000 employees may lead to bureaucratic challenges or feeling disconnected from leadership
  • Detailed employee review data and specific nurse satisfaction metrics were not available in the provided research sources
compassionateteam-orienteddiverseinclusivemission-driventransformative

Living in Seneca, SC

Seneca, South Carolina sits near the Blue Ridge Mountains and the shores of Lake Keowee. This small upstate city offers nurses a peaceful, outdoorsy lifestyle with easy access to hiking, fishing, and scenic lake views.

Map showing the location of Seneca, SC
Seneca, SC on the map · © Mapbox © OpenStreetMap· Open the live map
State price level · South Carolina
93.7
6% below the national average
Median gross rent
$807/mo
rent and tenant-paid utilities

U.S. Bureau of Economic Analysis · 2024 Regional Price Parities · Census ACS 2024

Browse open roles in Seneca

On your path

Pediatrics is a first-year unit lane. Families are part of every care plan.

Worth asking

The posting doesn’t answer these. Good ones to ask a recruiter or in the interview.

  • Can you walk me through the base pay range and differentials?
  • What should I expect for shifts, weekly hours, weekend, holiday, and rotation?
  • What orientation, preceptor time, and ongoing unit support are included?
  • How are patient load, floating, and staffing support handled day to day?
Open the full posting report

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