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Registered Nurse (RN) - Acute Care, Oncology, FT, Night

Prisma Health

Greenville, South Carolina 29605

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RNAcute CareOncology

Posted Jul 28, 2026 · Last seen active Jul 29, 2026

About this role

Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, SC DPH, CMS). Provides care within the scope of the South Carolina Nurse Practice Act. The acute inpatient setting may require staff to be scheduled for a weekend, holiday, and on-call work.

Requirements

  • Associate degree in Nursing (Bachelor's degree in Nursing preferred)
  • One (1) year experience as a registered nurse
  • Current RN compact/multistate license recognized by the NCSBN Compact State or licensed to practice as an RN in the state
  • Acute care experience
  • Inpatient experience
  • Oncology experience
  • Night shift, weekends as needed, on call

Benefits

  • Sign-On Bonus

About the employer

Prisma Health logo
Prisma Health
Academic Medical Center

Prisma Health is a large South Carolina-based healthcare system with nearly 32,000 team members, serving communities across the state including its Columbia market. The organization describes itself as being on a journey to transform the healthcare experience for patients and…

2.4 Google rating

What reviewers appreciate

  • Large health system with approximately 32,000 team members, offering diverse nursing career paths and settings
  • Remote nursing positions available for South Carolina residents, including post-discharge outreach roles
  • Strong stated commitment to diversity, inclusion, and valuing different backgrounds and lived experiences

What reviewers flag

  • Extensive compliance and policy requirements may create administrative burden for nursing staff
  • Large organizational size of nearly 32,000 employees may lead to bureaucratic challenges or feeling disconnected from leadership
  • Detailed employee review data and specific nurse satisfaction metrics were not available in the provided research sources

Benefits: Prisma Health states it offers a variety of health and wellness benefits designed to cover all aspects of employees' lives.

compassionateteam-orienteddiverseinclusivemission-driventransformative

Living in Greenville, SC

Greenville blends Southern charm with a revitalized downtown anchored by Falls Park on the Reedy River. The Main Street corridor offers walkable dining, breweries, and weekly farmers markets. Nestled in the foothills of the Blue Ridge Mountains, Greenville delivers mild four-season weather and an increasingly active healthcare corridor.

Map showing the location of Greenville, SC
Greenville, SC on the map · © Mapbox © OpenStreetMap
Metro price level · Greenville area
93.3
7% below the national average
Median gross rent
$1,312/mo
rent and tenant-paid utilities

U.S. Bureau of Economic Analysis · 2024 metro Regional Price Parities · Census ACS 2024

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