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199 nursing jobs in Roanoke, VA

Nestled in the Blue Ridge Mountains beneath the iconic Mill Mountain Star, Roanoke pairs clinical career growth with immediate access to the Roanoke River Greenway. Shifts give way to mountain trailheads, while a cost of living about 6% below the national average ensures your nursing paycheck delivers real breathing room.

Roanoke, VA on the map· Open the live map
Carilion Roanoke Memorial Hospital workplace
Carilion Roanoke Memorial Hospital — a workplace named in a current Roanoke postingView Carilion Roanoke Memorial Hospital →

Find a nursing job in Roanoke

Hiring here: Carilion Medical Center (132) · Carilion Clinic (13) · PRMC Operations LLC (4) · Brookdale Senior Living Inc. (3) · Carilion Healthcare Corporation (3) · Carilion Professional Services LLC (3)

Carilion Roanoke Memorial Hospital logo

Carilion Roanoke Memorial Hospital

Roanoke, VA

RN

$64/hr

  • RN
  • 10-⁠hour days
  • Travel contract
1 / 2

Paramedic

Carillion Roanoke Memorial Hospital logoCarillion Roanoke Memorial Hospital

Roanoke, VA

$26–$39/hr

  • 12-⁠hour nights
  • Tuition reimbursement
Carilion Clinic logo

Carilion Clinic

Roanoke, VA · Health system employer

RN - Medical Progressive Care Unit

Posted last week

$34–$50/hr

  • RN
  • Day shift
Mediko INC logo

Mediko INC

Roanoke, VA

  • New grads welcomed
  • LPN
  • 12-⁠hour shifts rotating 3/4 days
BrightStar Care of Central/SW VA logo

BrightStar Care of Central/SW VA

Roanoke, VA

  • RN
  • Day shift
  • Agency contract

GameDay Men's Health Glenwood

Roanoke, VA

  • RN
  • Primarily Monday–Friday, with occasional evening call blocks as needed

TwelveStone Health Partners Inc

Roanoke, VA

Registered Nurse

$40–$43/hr

  • RN
  • ADN accepted
HarmonyCares logo

HarmonyCares

Roanoke, VA

  • RN
  • Day shift
  • Tuition reimbursement

Carilion Medical Center

Roanoke, VA

RN Clinical Coordinator - Inpatient Dialysis

Posted 3 days ago

$105,000/year

  • RN

Carilion Professional Services LLC

Roanoke, VA

CRNA, Full time

Posted last week

$200/hr

  • Sign-on bonus
  • CRNA
  • 12-⁠hour days

Carilion Emergency Services Inc

Roanoke, VA

  • NP
  • 8-⁠hour days

PRMC Operations LLC

Roanoke, VA

  • CNA
  • Evening shift

PR Operations LLC

Roanoke, VA

  • CNA
  • Night shift

Candis

Roanoke, VA

LPN

$25–$35/hr

  • New grads welcomed
  • LPN

Affinity Care of Virginia

Roanoke, VA

Hospice RN Case Manager

$79,000–$89,000/year

  • Sign-on bonus
  • RN
  • ADN accepted
Comprehensive Treatment Centers logo

Comprehensive Treatment Centers

Roanoke, VA

  • LPN
  • Day shift
  • Tuition reimbursement

Pheasant Ridge AL Operations LLC

Roanoke, VA

CNA|Part time| 11PM-7AM

Posted last week

  • CNA
  • Night shift
GameDay Men's Health logo

GameDay Men's Health

Roanoke, VA

  • RN
  • Primarily Monday–Friday, with occasional evening call blocks as needed

Virginia Department of Health

Roanoke, VA

PH Nurse (VDHRN012)

Posted 3 days ago

$55,000–$76,000/year

  • RN
Nest Homecare LLC logo

Nest Homecare LLC

Roanoke, VA

  • RN
  • Day shift

Carilion Healthcare Corporation

Roanoke, VA

  • RN
  • Day shift
Agape Care Group logo

Agape Care Group

Roanoke, VA

  • RN

Carilion Clinic

Roanoke, VA

  • RN
  • Day shift
Mediko INC logo

Mediko INC

Roanoke, VA

  • RN
  • Night shift
  • ADN accepted

Carilion Medical Center

Roanoke, VA

  • NP/RN
  • Day shift

Carilion Professional Services LLC

Roanoke, VA

CRNA, Full time

Posted last week

$200/hr

  • Sign-on bonus
  • CRNA
  • 12-⁠hour days

PRMC Operations LLC

Roanoke, VA

  • CNA
  • Day shift

PR Operations LLC

Roanoke, VA

Caregiver - FT

Posted today

  • CNA
GameDay Men's Health logo

GameDay Men's Health

Roanoke, VA

  • RN
  • Primarily Monday–Friday, with occasional evening call blocks as needed

Carilion Healthcare Corporation

Roanoke, VA

APP (NP/PA) Family & Rural Medicine Fellow

Posted last week

$69,000/year

  • NP

Carilion Clinic

Roanoke, VA

RN - Cardiac PCU

$34–$50/hr

  • RN
  • Rotating shift

Carilion Medical Center

Roanoke, VA

  • RN

Carilion Professional Services LLC

Roanoke, VA

  • CRNA
  • Day shift

PRMC Operations LLC

Roanoke, VA

CNA | Full Time

Posted last week

$19/hr

  • CNA
Carilion Clinic logo

Carilion Clinic

Roanoke, VA · Health system employer

RN I - Operating Room

Posted 2 weeks ago

$34–$50/hr

  • New grads welcomed
  • RN
  • Any Day, Any Shift

Carilion Medical Center

Roanoke, VA

APP Fellow- Acute Care Surgery

Posted today

$69,000/year

  • NP

PRMC Operations LLC

Roanoke, VA

  • CNA
  • Day shift
Carilion Clinic logo

Carilion Clinic

Roanoke, VA · Health system employer

RN Oncology

Posted last week

$34–$50/hr

  • New grads welcomed
  • RN
  • Night shift

Carilion Medical Center

Roanoke, VA

Home Health Nurse- Wound Specialist

Posted last week

$115,000/year

  • RN
  • Day shift
Carilion Clinic logo

Carilion Clinic

Roanoke, VA · Health system employer

Carilion Travel RN - E/N

Posted last week

$59

  • RN
  • Night shift
  • Travel contract

Carilion Medical Center

Roanoke, VA

APP Cardiothoracic Surgery - Weekends

Posted 2 weeks ago

$173,000/year

  • NP/RN
  • Weekend shift
Carilion Clinic logo

Carilion Clinic

Roanoke, VA · Health system employer

RN - Vascular Surgery OR, CVOR

Posted last week

$34–$50/hr

  • RN
  • Rotating shift

Carilion Medical Center

Roanoke, VA

RN Case Manager

Posted last week

$115,000/year

  • RN
  • Day shift
Carilion Clinic logo

Carilion Clinic

Roanoke, VA · Health system employer

RN I - Practice - Bariatric Surgery

Posted last week

$28–$42/hr

  • RN
  • Day shift

Carilion Medical Center

4 open roles · Permanent

RN Case Manager - Weekends - Full time

Roanoke, VA · Posted last week

$115,000/year

  • RN
  • 12-⁠hour weekends only

APP ( NP or PA) - Cardiothoracic Surgery

Roanoke, VA · Posted last week

$173,000/year

  • NP
  • Day shift

Practice Supervisor - RN - Interventional Radiology Clinic

Roanoke, VA · Posted 2 weeks ago

$105,000/year

  • RN

APP ( NP or PA) - Cardiothoracic Surgery

Roanoke, VA · Posted last week

$173,000/year

  • NP
  • Day shift

Working and living in Roanoke

· 199 open roles

Posted hourly pay

RN
$34/hr median
$34–$41/hr middle half · 17 postings

See roles with listed pay

Living costs

Metro price level
93.6 (100 = national)
BEA 2024
Median gross rent
$996/mo
Rent and tenant-paid utilities
Median household income
$55,378/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

17 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

25 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • CRNA3
  • NP11
  • APRN1
  • RN145
  • LPN30
  • LVN2
  • CNA11

One posting may accept more than one credential.

Shifts listed

  • Days99
  • Nights31
  • per-diem29
  • Rotating13
  • Evenings3
  • weekend3

Postings may list several shifts or leave the shift unspecified.

Living in Roanoke

Framed by the Blue Ridge Mountains, Roanoke—the 'Star City of the South'—combines the clinical heft of a regional healthcare hub with the relaxed pace of an Appalachian mountain city.

More about life here

Anchored by major employers like Carilion Clinic, Roanoke draws medical professionals who want short commutes without sacrificing outdoor adventure or cultural character. Downtown offers an energetic urban setting where loft living sits steps from the Historic City Market, the Taubman Museum of Art, and acclaimed independent dining spots such as Lucky and Fortunato.

Relocating nurses seeking quiet neighborhoods with strong schools often select South Roanoke, suburban Cave Spring, or the independent community of Salem. Outdoor recreation is woven directly into everyday life: shift workers can decompress with a trail run at Carvins Cove Natural Reserve, hike Mill Mountain Park to view the illuminated Roanoke Star, or cycle the paved Roanoke River Greenway.

Practical trade-offs include high car dependency for daily errands, limited direct flights from the regional airport, and visible urban social challenges in pockets of the city core. However, Roanoke rewards healthcare workers with exceptional accessibility, tight-knit mountain hospitality, and world-class trails right outside their front door.

Sources
As of Sep 16, 2026
Neighborhoods

Healthcare professionals and residents gravitate toward distinct pockets across the valley depending on lifestyle preferences. Downtown Roanoke offers urban loft apartments and condominiums within walking distance of the Historic City Market, Elmwood Park, and independent restaurants, appealing to medical residents and early-career staff.

Directly south, South Roanoke is an established, sought-after residential enclave featuring historic architecture and tree-lined streets situated immediately adjacent to major Carilion Clinic facilities. Suburban enclaves like Cave Spring and Hidden Valley in southwest Roanoke County provide established subdivisions near the Route 419 commercial corridor, while the independent city of Salem and the community of Vinton offer small-town character, independent school options, and manageable surface commutes into the urban core.

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Housing

The valley presents a diverse spectrum of residential housing options ranging from urban adaptive reuse to rural hillside properties. Downtown Roanoke offers loft living and modern apartments within restored commercial structures, while South Roanoke features high-demand classic brick homes, colonials, and cottages on established lots.

Buyers and renters looking for mid-century single-family homes and newer subdivisions often turn to suburban Cave Spring and Hidden Valley in Roanoke County. Those seeking broader value or small-city neighborhood charm frequently explore Vinton, North Roanoke County, or the independent city of Salem, while Daleville in Botetourt County provides newer planned communities.

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Getting around

Commuting throughout the Roanoke Valley is generally brief and predictable compared to major metropolitan centers. Interstate 581 cuts north-south through the city, linking regional traffic from Interstate 81 directly to downtown, the regional airport, and the Carilion Clinic medical campus.

Nurses living in South Roanoke or Downtown can reach clinical facilities in minutes via local surface streets or active bicycle commuting along the Roanoke River Greenway. Living in suburban Cave Spring, Salem, or Botetourt County requires a personal vehicle due to the region's overall car dependency, but travel times across the valley floor rarely involve heavy gridlock outside of standard peak traffic along primary arteries like Route 419.

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Food and dining

Roanoke supports an independent and varied culinary scene concentrated heavily around the Historic City Market and downtown walkable corridors. Downtown mainstays like Fortunato, Lucky, Billy's, and Sidecar emphasize local ingredients, craft cocktails, and regional dining flair rather than national chains.

For everyday dining and shift-friendly meal options, clinicians frequent neighborhood cafés, local bakeries, and casual spots clustered along suburban corridors such as Route 419 near Cave Spring, as well as classic diners and neighborhood taverns throughout Grandin Village and Salem.

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Outdoors

Known as the Capital of the Blue Ridge, Roanoke provides exceptional year-round outdoor recreation integrated directly into residential routines. Carvins Cove Natural Reserve spans over twelve thousand acres with more than sixty miles of multi-use trails, standing out as a premier East Coast destination for mountain biking, trail running, and reservoir paddling.

Within city borders, Mill Mountain Park features extensive nature trails crowned by the famous illuminated Roanoke Star and the Mill Mountain Zoo. Residents also frequent the paved Roanoke River Greenway for jogging and cycling, as well as the nearby Blue Ridge Parkway and Appalachian Trail ridgelines.

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Arts and culture

Roanoke balances its historic railroad identity with an active mountain arts and entertainment scene. Downtown features the striking contemporary architecture of the Taubman Museum of Art and the Virginia Museum of Transportation, which celebrates the city's rich locomotive history.

Elmwood Park acts as an outdoor civic amphitheater hosting live music, outdoor movies, and large regional events like Festival in the Park. Major indoor arena shows, sports, and touring performances are staged between the Berglund Center in Roanoke and the Salem Civic Center in neighboring Salem.

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Seasons and weather

The Roanoke Valley experiences four well-defined seasons framed by surrounding mountain ridges. Autumn is particularly celebrated, as fall foliage across the Blue Ridge Parkway peaks in mid- to late October, drawing locals and visitors outdoors to overlooks and hiking trails.

Summers are warm and humid, ideal for reservoir kayaking at Carvins Cove or river walks along the greenway, while winters remain generally mild to moderate with occasional snowfalls that rarely disrupt valley operations for long. Spring brings rapid greening across the valley floor, though elevation changes along the mountain ridgelines can lead to noticeable temperature swings.

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For families

Families relocating to the area often look to the suburban communities of Roanoke County and the independent city of Salem, which operates its own highly regarded municipal school district and maintains a close-knit sports culture. Cave Spring is widely viewed by residents as a safe, family-centric area with strong public school options, well-maintained parks, and accessible grocery shopping.

Daleville in Botetourt County also attracts growing families seeking quieter settings and newer amenities, while community-focused attractions such as the Mill Mountain Zoo and Discovery Center offer accessible weekend outings for young children.

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What locals say

Residents consistently praise Roanoke for its unmatched outdoor accessibility, community friendliness, and surprisingly diverse dining scene for an Appalachian mountain city. Relocating healthcare workers appreciate escaping crushing big-city traffic, noting that nature trails and city centers are both minutes away.

On the trade-off side, locals point out high reliance on personal automobiles, regional airport limitations with fewer direct flights, and a job market that is heavily centralized around healthcare networks. Community discussions also note visible urban social challenges, including localized homelessness and uneven public school performance across different municipal borders.

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