Skip to content

13 nursing jobs in Upland, CA

Anchored by San Antonio Regional Hospital against the San Gabriel Mountains, Upland provides peaceful foothill living. Decompress along Euclid Avenue’s three-mile tree-lined median trail, grab post-shift coffee at Lucky’s Coffee Roasters in Historic Downtown, or slip ten minutes west to neighboring Claremont Village when you want lively college-town dining.

Upland, CA on the map· Open the live map
Starling Oncology workplace
Starling Oncology — a workplace named in a current Upland postingView Starling Oncology →

Find a nursing job in Upland

Hiring here: Precision Scans INC (4) · Generations Healthcare (2) · City of Hope (1) · DPS HEALTHCARE (1) · Genus Home Care (1) · MEDEX STAFFING NETWORK LLC (1)

  • RN
  • Day shift
  • Tuition reimbursement
1 / 3
  • LVN
  • 8-⁠hour nights
  • Per diem

San Antonio Ambulatory Surgical Center

Upland, CA

  • RN

Telemetry RN

$50–$53/hr

  • RN
  • 12-⁠hour days
  • Local contract
  • LVN
  • PM shift 3pm-11pm with weekend availability
City of Hope logo

City of Hope

Upland, CA

  • RN
  • 10-⁠hour shifts
  • Floating required

DPS Healthcare

Upland, CA

Home Infusion RN

$80–$100/hr

  • RN

MEDEX Staffing Network LLC

Upland, CA · Staffing partner

Registered Nurse NICU

Posted 5 days ago

  • RN
  • Rotating shift

Precision Scans INC

3 open roles · night & day shifts · Hospital

RN MedSurg/Tele

Upland, CA

$47–$55/hr

  • RN
  • 12-⁠hour nights
  • Agency contract

Registered Nurse - Telemetry

Upland, CA

$50–$55/hr

  • RN
  • 12-⁠hour nights
  • Travel contract

11550542 RN - ER

Upland, CA

$55–$60/hr

  • RN
  • AM (07:00 - 19:30)
  • Agency contract

Working and living in Upland

· 13 open roles

Posted hourly pay

RN
$50/hr median
$47–$51/hr middle half · 8 postings

See roles with listed pay

Living costs

Median gross rent
$2,029/mo
Rent and tenant-paid utilities
Median household income
$105,830/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

0 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

1 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • RN11
  • LVN2

One posting may accept more than one credential.

Shifts listed

  • Days3
  • Nights3
  • Evenings1
  • Rotating1

Postings may list several shifts or leave the shift unspecified.

Living in Upland

Positioned against the base of the San Gabriel Mountains, Upland offers healthcare professionals a quiet foothill lifestyle anchored by major regional employers like the 300-plus bed San Antonio Regional Hospital.

More about life here

Originally built on citrus groves, the city today balances preserved character—showcased along the historic three-mile Euclid Avenue walking trail and downtown boutiques—with convenient access to regional corridors via the Foothill Freeway, Interstate 10, and Metrolink rail service. Prospective residents can choose between townhomes and apartments south of Foothill Freeway or established single-family neighborhoods climbing toward the mountains.

Life here emphasizes outdoor activity and family living, with weekend recreation along the Cucamonga Creek Trail, events like the annual April Lemon Festival, and well-regarded local campuses within the Upland Unified School District. Relocating nurses should weigh practical trade-offs: summer heat frequently climbs above 95 degrees, occasional wildfire and air quality alerts require vigilance, and the city's nightlife is subdued enough that locals routinely drive to adjacent Claremont for an expanded dining scene.

Sources
As of Sep 16, 2026
Neighborhoods

Prospective residents often gravitate toward Historic Downtown Upland around North Euclid Avenue and East Foothill Boulevard, which offers a walkable setting lined with local shops, cafes, and older housing stock. Suburban single-family enclaves, built largely between the 1940s and 1990s, populate the central and northern stretches toward the foothills, while older character properties sit in historic pockets like Old Magnolia.

Condominiums and townhomes are concentrated south of the Foothill Freeway, and manufactured home communities are situated off 13th Street.

Sources
Housing

The local housing stock consists primarily of single-family homes built across the mid-to-late 20th century, balanced by modern multi-family complexes, condominiums, and townhomes. Condominium units and multi-unit developments are largely situated south of the Foothill Freeway, while manufactured home options are available near 13th Street.

Established standalone houses spread northward toward the mountains, though steady buyer competition and established owner-occupancy limit the turnover of entry-level detached properties.

Sources
Getting around

Commuting within the city is centered around arterial corridors like Route 66 (Foothill Boulevard) and Euclid Avenue, providing direct access to local facilities like San Antonio Regional Hospital. Regional transit is supported by the Metrolink line connecting Los Angeles and San Bernardino, along with local Omni bus routes.

Highway drivers face peak-hour congestion on Interstate 10 into Los Angeles—which takes under an hour in clear conditions—and along the Foothill Freeway toward Pasadena or San Bernardino, accompanied by noticeable traffic noise along major thoroughfares.

Sources
Food and dining

Dining options are clustered along Route 66 and throughout Historic Downtown Upland, featuring casual eateries, craft breweries, and local morning stops like Lucky's Coffee Roasters. While downtown holds social gatherings like the '2nd on 2nd' outdoor dining and entertainment nights, many residents regularly travel to neighboring Claremont Village to access a broader selection of independent restaurants, cafes, and evening venues.

Sources
Outdoors

Sitting at the base of the San Gabriel Mountains, Upland provides immediate access to trails and green spaces. Euclid Avenue features a distinctive 3-mile tree-lined median path popular for jogging and walking, while the Cucamonga Creek Trail connects multiple trailheads across biodiverse terrain.

The city oversees 20 parks, including McCarthy Park, Olivedale Park, Fern Reservoir, and a dedicated dog park, with longer regional outings available nearby at Marshall Canyon Trail in La Verne and Chino Hills State Park.

Sources
Arts and culture

Upland's cultural identity honors its citrus-growing past, most visibly during the annual Upland Lemon Festival held each April with entertainment, food vendors, and community activities. Historic Downtown hosts seasonal weekend farmers markets alongside community events like '2nd on 2nd.' The city also retains historical touchstones such as the Madonna of the Trail monument along historic Route 66 and a storied heritage in Southern California skateboarding culture.

Sources
Seasons and weather

The climate is predominantly sunny with low humidity year-round, but inland summer temperatures regularly surpass 95 degrees, driving up cooling needs and limiting mid-day outdoor activities. Dry vegetation and foothill terrain introduce seasonal wildfire conditions managed by the San Bernardino County Fire Department, while atmospheric inversions produce roughly 20 days per year of unhealthy air quality where outdoor masking or indoor precautions are recommended.

Sources
For families

Families are served by the Upland Unified School District, which operates 14 campuses including Pepper Tree Elementary, Valencia Elementary, Upland Elementary, Upland Junior High, and Upland High, featuring STEAM programs and technical education pathways. Private alternatives include Western Christian and St. Joseph.

Overall crime rates run lower than state averages, with neighborhoods supported by recreational hubs like McCarthy Park and Olivedale Park.

Sources
What locals say

Residents characterize Upland as a safe, peaceful suburban bedroom community set against scenic mountain foothills, praising its access to regional shopping and outdoor spaces. However, locals frequently note that the dining and nightlife scenes within city limits are relatively quiet, often leading people to head ten minutes west to neighboring Claremont for college-town energy.

Other common frustrations include intense summer heat, occasional regional air quality advisories, Santa Ana wind concerns, and heavy reliance on cars for daily errands.

Sources

Other cities