48 nursing jobs in Yankton, SD
Yankton sits along the Missouri River near Lewis and Clark Lake, offering nurses a quiet, outdoorsy lifestyle in a historic South Dakota river town. Expect a close-knit community feel, easy commutes, and abundant fishing, boating, and trail access—ideal for those who prefer small-town living with natural amenities over urban bustle.
Find a nursing job in Yankton
Hiring here: Sacred Heart Health Services (36) · Avera McKennan (5) · Vibra Travels LLC (2) · American Traveler (1) · Avera (1) · Avera Health (1)
- NP
- Day Shift (United States of America)
Nursing Assistant or Certified Nursing Assistant (CNA) | Hospice House
Yankton, SD
$20–$28/hr
- Sign-on bonus
- CNA
- 12-hour nights
- New grads welcomed · reported
- Sign-on bonus
- RN
- Monday-Friday, days; 40 hours a week
- Tuition reimbursement
- NP
- Day shift
- Sign-on bonus
- RN
- Monday-Friday, 3 days per week
- Tuition reimbursement
Registered Nurse (RN) Float | Med Surg
Yankton, SD · Posted last week
$35/hr
- Sign-on bonus
- RN
- 7pm-7am & 7am-7pm; 72hrs/2wks; Every 3rd weekend/holiday
- Tuition reimbursement
- RN
- PRN/fill in as needed; Monday-Friday, Days
- Per diem
- Sign-on bonus
- CNA
- 8-hour days
- Sign-on bonus
- RN
- Monday-Thursday 8am-5pm & Friday 8am-12pm; 72hrs/2wks
- Tuition reimbursement
- Sign-on bonus
- RN
- Rotating shift
- Tuition reimbursement
- RN
- Days, Monday-Friday; 40hrs/2wks

Sacred Heart Health Services
31 open roles
Sacred Heart Health Services
31 open roles
- Sign-on bonus
- RN
- 8-hour days
- Tuition reimbursement
- Sign-on bonus
- RN
- 7pm-7am & 7am-7pm; 72hrs/2wks; Every 3rd weekend/holiday
- Tuition reimbursement
- Sign-on bonus
- RN
- Day shift
- Tuition reimbursement
- Sign-on bonus
- CNA
- 5:30pm-6am; Every 3rd weekend/holiday rotation; 72hrs/pp
- Floating required
- CNA
- Rotating shift
- Sign-on bonus
- LPN
- Days - 8am-5pm (flexible); Every 6th weekend/holiday rotation
- Tuition reimbursement
- Sign-on bonus
- RN/LPN
- 7pm-7am & 7am-7pm; 72hrs/2wks; Every 3rd weekend/holiday
- Tuition reimbursement
- Sign-on bonus
- RN
- Rotating shift
- Tuition reimbursement
- RN
- Day shift
- Tuition reimbursement
Registered Nurse (RN) | Pre-Post Operative
Yankton, SD · Posted 4 days ago
- RN
- 8-hour shifts
- Sign-on bonus
- RN/LPN
- Day shift: 6am-6:30pm; Every 3rd weekend/holiday, 48hrs/2wks
- Tuition reimbursement
Registered Nurse (RN) FLOAT | Med Surg
Yankton, SD · Posted 5 days ago
- Sign-on bonus
- RN
- Rotating shift
- RN
- Rotating shift
Registered Nurse (RN) | Emergency Unit
Yankton, SD · Posted 5 days ago
- Sign-on bonus
- RN
- Rotating shift
- Sign-on bonus
- RN/LPN
- Night shift: 6pm-6:30am; Every 3rd weekend/holiday, 72hrs/2wks
- Tuition reimbursement
Nursing Assistant or Certified Nursing Assistant (CNA) | Long Term Care
Yankton, SD · Posted 5 days ago
- Sign-on bonus
- CNA
- Rotating shift
Registered Nurse (RN) or Licensed Practical Nurse (LPN) or Medical Assistant | Family Medicine Clinic
Yankton, SD
$20/hr
- Sign-on bonus
- RN/LPN
- Monday-Friday, Days; 40 hours a week
- Tuition reimbursement
Certified Nursing Assistant (CNA) or Nurse Assistant FLOAT | Long Term Care
Yankton, SD · Posted 6 days ago
- Sign-on bonus
- CNA
- Night shift
- RN/LPN
- PRN/fill in as needed; Monday-Friday, days
- Per diem
Certified Nursing Assistant (CNA) or Nurse Assistant | Hospice House
Yankton, SD · Posted 6 days ago
- CNA
- RN/LPN
- 6pm-6:30am; 20hrs/2wks
Registered Nurse (RN) | Long Term Care
Yankton, SD · Posted last week
- Sign-on bonus
- RN
- Day shift
- Sign-on bonus
- RN
- 7pm-7am & 7am-7pm; 48hrs/2wks; Every 3rd weekend/holiday
- Tuition reimbursement
Registered Nurse (RN) Quality Specialist
Yankton, SD · Posted last week
- RN
- Day shift
- Sign-on bonus
- RN
- Monday - Friday, 3 shifts per week; 48hrs/2wks
- Tuition reimbursement
Registered Nurse (RN) | Podiatry Clinic
Yankton, SD · Posted last week
- Sign-on bonus
- RN
- Day shift
Registered Nurse (RN) or Licensed Practical Nurse (LPN) or Medical Assistant | Family Medicine Clinic
Yankton, SD
$20/hr
- Sign-on bonus
- RN/LPN
- Monday-Friday, Days; 40 hours a week
- Tuition reimbursement
Registered Nurse (RN) House Supervisor
Yankton, SD
- RN
- 12-hour nights
- New grads welcomed
- RN
- Rotating shift
- Per diem
- Sign-on bonus
- CNA
- 6am-6:30pm; Every 3rd weekend/holiday rotation; 72hrs/pp
- Floating required
- New grads welcomed
- RN
- 6am-6:30pm; 3-12hr shifts per week, Every 3rd weekend/holiday rotation
- Per diem
Registered Nurse (RN)
$35–$40/hr
- Sign-on bonus
- RN
- 12-hour rotating
- Compact license OK
Travel RN - Telemetry
$2,434/week
- RN
- 12-hour nights
- Travel contract
Working and living in Yankton
· 48 open roles
Posted hourly pay
- RN
- $28/hr median
- $25–$33/hr middle half · 23 postings
- LPN
- $25/hr median
- $23–$25/hr middle half · 9 postings
- CNA
- $20/hr median
- $20–$20/hr middle half · 5 postings
New to our board this week
7 current postings first appeared here in the past seven days.
Credentials accepted
- NP2
- RN36
- LPN9
- CNA8
One posting may accept more than one credential.
Shifts listed
- Days23
- Rotating13
- Nights7
- per-diem1
Postings may list several shifts or leave the shift unspecified.
Living in Yankton
Positioned along the Missouri River in southeastern South Dakota, Yankton combines small-town community warmth with regional healthcare importance.
More about life hereShow less
For relocating nurses, Avera Sacred Heart Hospital serves as a major employer anchored within a community of roughly 15,000 residents. Daily life offers seamless logistics: average commutes run approximately 9 minutes, eliminating stressful urban traffic.
Off duty, life centers around the water. Lewis and Clark Lake, the Lewis and Clark Recreation Area, and the iconic pedestrian Meridian Bridge provide exceptional boating, fishing, and trail walking right at your doorstep.
The historic downtown features cultural stops like the G.A.R. Hall Gallery and dining favorites like Willa B's Bistro and Chaparro's Tacos. The trade-offs reflect its small scale: public transit is minimal, requiring a personal vehicle, and winter brings substantial snow alongside quiet nightlife that mostly wraps up early.
For clinicians seeking outdoor recreation and an unhurried daily rhythm, Yankton offers a grounded, welcoming river-town lifestyle.
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Neighborhoods
Residential living in Yankton centers around established residential corridors along streets like Douglas Avenue near Mount Marty University, quiet pockets such as Castlewood Circle and Bunker Lane, and riverside neighborhoods adjacent to Riverside Park and historic downtown. Outlying residential pockets extend west toward Lewis and Clark Lake, where resort-style and recreational properties appeal to those seeking scenic water views.
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Housing
Housing in Yankton is dominated by established single-family homes with mature yards, alongside modest rental clusters situated near Mount Marty University and Avera Sacred Heart Hospital. Neighborhoods range from older craftsman and mid-century homes in central districts along avenues like Douglas to newer suburban builds and cul-de-sacs.
Premium properties are typically found west of town near Lewis and Clark Lake.
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Getting around
Commutes in Yankton are exceptionally quick, averaging roughly 9 minutes across town. Healthcare workers commuting to Avera Sacred Heart Hospital or Mount Marty University face virtually no highway gridlock.
Daily travel is overwhelmingly car-oriented, as public transit is limited to select dial-a-ride or specialized services, and local bike routes are largely geared toward recreational trail riding rather than utility transit.
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Food and dining
Yankton's dining revolves around independent local favorites in the historic downtown district and near the riverfront. Notable staples include casual spots like Willa B's Bistro, authentic street food at Chaparro's Tacos, and waterfront dining near the marina at The Boat House.
While traditional Midwestern fare and local diners are easy to find, late-night options after evening nursing shifts are limited.
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Outdoors
Outdoor recreation is Yankton's defining feature, anchored by Lewis and Clark Lake and the Missouri River. Residents frequent the Lewis and Clark Recreation Area for camping, boating, and beach outings, as well as the Lewis and Clark Resort.
In town, Riverside Park provides paved riverfront multi-use trails, and the double-deck pedestrian Meridian Bridge offers walking and biking across the Missouri River, while anglers head to Gavins Point National Fish Hatchery.
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Arts and culture
Yankton's cultural offerings emphasize pioneer history and regional fine art. Downtown showcases rotating murals, seasonal studio tours, and art walks, while the G.A.R. Hall Gallery and Cultural Center displays monthly exhibitions from regional creators.
History buffs also explore the Dakota Territorial Capitol Replica in Riverside Park, commemorating Yankton's role as the initial capital of Dakota Territory.
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Seasons and weather
Residents experience distinct four-season Northern Plains weather. Winters are cold and windy, bringing an average of 35 inches of snowfall that demands winter driving preparation.
Springs and autumns are brief but pleasant, leading into warm summer months that average 27 inches of annual rainfall and create prime conditions for boating and water recreation on the lake.
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For families
Yankton provides a quiet, family-oriented environment characterized by low noise and a strong, rooted resident base. Primary and secondary education is administered through the Yankton School District, complemented by private parochial schools and higher education at Mount Marty University.
Family entertainment includes Riverside Park playgrounds, outings along Lewis and Clark Lake, and Karttrax Go-Kart & Family Fun Park.
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What locals say
Community discussions characterize Yankton as a safe, peaceful river community with deep small-town charm and unparalleled access to boating, hunting, and fishing. Longtime residents value the calm atmosphere and strong local hospital infrastructure.
On the downside, some newcomers and online commenters note a slower social pace, limited nightlife options outside outdoor recreation, and occasional frustrations with civic management.