Skip to content

22 nursing jobs in Mitchell, SD

Anchored by the iconic Corn Palace, Mitchell pairs low-stress prairie living with sub-ten-minute hospital commutes. Settle into quiet, tree-shaded pockets along East 7th or near Lake Mitchell for easy kayaking and shoreline trails. Shift recovery comes easy downtown with craft pours at Palace City Brewing, trading highway gridlock for grounded Midwestern calm an hour west of Sioux Falls.

Mitchell, SD on the map· Open the live map
Avera Queen of Peace workplace
Avera Queen of Peace — a workplace named in a current Mitchell postingView Avera Queen of Peace →

Find a nursing job in Mitchell

Hiring here: Avera Queen of Peace (11) · American Traveler (2) · Vetted Solutions (2) · Aura Health (1) · Avera (1) · Avera Health (1)

Avera Queen of Peace

Mitchell, SD

  • Sign-on bonus
  • CNA
  • 6:00pm-6:30am; 72hrs/2wks including every third weekend and holiday.
1 / 3
  • Sign-on bonus
  • CRNA/RN
  • Day shift
1 / 2

Registered Nurse (RN)

Peaceful Pines Senior Living logoPeaceful Pines Senior Living

Mitchell, SD

  • RN
1 / 2

Registered Nurse (RN) | Dialysis

Avera McKennan logoAvera McKennan

Mitchell, SD · Posted last week

$33/hr

  • Sign-on bonus
  • RN
  • Primarily days with rotating weekends and holidays
  • Tuition reimbursement
A photo of Avera Queen of Peace

Avera Queen of Peace

10 open roles

Registered Nurse (RN) | Emergency Unit

Mitchell, SD · Posted last week

$33/hr

  • Sign-on bonus
  • RN
  • 6am-6pm, 11am-11pm and 6pm-6am; 72hrs/2wks
  • Tuition reimbursement
  • Sign-on bonus
  • CNA
  • 12-⁠hour nights

Registered Nurse (RN) | ICU

Mitchell, SD · Posted last week

$33/hr

  • Sign-on bonus
  • RN
  • 12-⁠hour rotating
  • Tuition reimbursement
  • Sign-on bonus
  • CNA
  • 5:45am-6:15pm; 72hrs/2wks

Registered Nurse (RN) | Med Surg

Mitchell, SD · Posted last week

$33/hr

  • Sign-on bonus
  • RN
  • 12-⁠hour rotating
  • Tuition reimbursement

Registered Nurse (RN) | Women's Center

Mitchell, SD · Posted last week

$33/hr

  • Sign-on bonus
  • RN
  • 12-⁠hour nights
  • Tuition reimbursement
  • Sign-on bonus
  • RN/LPN
  • 6:00pm-6:30am; 72hrs/2wks
  • Tuition reimbursement
  • CNA
  • 2:00pm-10:30pm, 4:00pm-10:30pm and 6:00pm-10:30pm; 24hrs/2wks

Registered Nurse (RN) | Medical Oncology | PRN

Mitchell, SD · Posted last week

  • RN
  • Per diem

Nurse Clinical Internship (NCI)

Mitchell, SD · Posted last week

  • New grads welcomed
  • RN
  • 12-⁠hour rotating

State of South Dakota

Mitchell, SD

  • RN
  • Night shift
  • Per diem
Avera logo

Avera

Mitchell, SD

  • Sign-on bonus
  • RN
  • Rotating shift
  • New grads welcomed
Aura Health logo

Aura Health

Mitchell, SD

  • RN
  • Day shift

Azza HealthCare Agency

Mitchell, SD · Staffing partner

  • RN
Vetted Solutions logo

Vetted Solutions

Mitchell, SD · Staffing partner

  • RN
American Traveler logo

American Traveler

Mitchell, SD · Staffing partner

  • RN
  • 12-⁠hour nights
  • Travel contract
Vetted Solutions logo

Vetted Solutions

Mitchell, SD · Staffing partner

  • RN
American Traveler logo

American Traveler

Mitchell, SD · Staffing partner

  • RN
  • 12-⁠hour nights
  • Travel contract

Working and living in Mitchell

· 22 open roles

Posted hourly pay

RN
$33/hr median
$32–$33/hr middle half · 8 postings

See roles with listed pay

Living costs

Median gross rent
$851/mo
Rent and tenant-paid utilities
Median household income
$58,620/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

2 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

0 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • CRNA1
  • RN18
  • LPN1
  • CNA4

One posting may accept more than one credential.

Shifts listed

  • Nights7
  • Rotating5
  • Days4
  • Evenings1
  • per-diem1

Postings may list several shifts or leave the shift unspecified.

Living in Mitchell

Mitchell offers relocating nurses an authentic, unhurried South Dakota lifestyle defined by tight-knit community ties, roadside Americana, and lakeside living.

More about life here

Anchored by the world-famous Corn Palace downtown, the city pairs distinctive heritage attractions like the Dakota Discovery Museum and the Mitchell Prehistoric Indigenous Archaeological Site with a walkable Main Street featuring local favorites such as Bread & Vine Bistro and Palace City Brewing. Everyday routines are uncomplicated: local commutes across town take under ten minutes, keeping transit stress minimal for hospital shift workers.

In fair weather, off-duty hours center on Lake Mitchell for boating, trail running, and kayaking, alongside community picnics in Hitchcock Park. The trade-offs lie in geographic isolation and climate: Mitchell sits roughly an hour west of Sioux Falls on Interstate 90, meaning specialized shopping or urban nightlife requires a highway drive.

Furthermore, winter on the plains brings severe windchills, blizzards, and freezing conditions that demand cold-weather resilience. For healthcare professionals seeking a peaceful, grounded town with minimal congestion and safe, welcoming neighborhoods, Mitchell provides a reliable, small-town Midwestern home.

Sources
As of Sep 16, 2026
Neighborhoods

Residential living in Mitchell centers around calm, tree-shaded streets near the historic core, quiet pockets along avenues like East 7th and East 13th, and residential clusters extending toward the north. Those seeking recreational access often settle closer to the Lake Mitchell area on the north side of town, while central neighborhoods provide quick foot or short-drive access to downtown conveniences.

Overall, residential sectors maintain a tranquil, suburban feel with low noise levels and established single-family homes alongside apartment complexes.

Sources
Housing

The housing landscape features a balanced blend of homeowners and renters, with options ranging from detached single-family houses with spacious yards to modest apartment buildings and multi-family units. Properties close to Lake Mitchell cater to those seeking lakeside views and outdoor access, while the core of the city features historic, tree-lined residential neighborhoods with older single-family bungalows and practical rentals suited for individual healthcare workers.

Sources
Getting around

Commutes within Mitchell are brief, with local trips typically taking under ten minutes across town. Driving is the dominant way to get around, as public transit is extremely limited.

The city is positioned directly along Interstate 90 roughly an hour west of Sioux Falls; while the interstate corridor makes regional travel straightforward, local residents note that attempting a daily commute between Sioux Falls and Mitchell is taxing, making living locally in Mitchell far more practical for shift workers.

Sources
Food and dining

Downtown Mitchell along Main Street serves as the community's culinary hub, featuring local gathering spots and casual bistros. Notable dining options include Mexican fare at El Columpio, refined dining at Bread & Vine Bistro, and craft beers at Palace City Brewing.

Outside of downtown and interstate corridors, dining options lean toward classic comfort food, cafes, and local bars, with late-night options tapering off early compared to regional metropolitan centers.

Sources
Outdoors

Outdoor recreation centers around Lake Mitchell on the city's north edge, where locals spend warmer months boating, kayaking, fishing, camping, and utilizing shoreline trails. Within town, residents have access to 14 municipal parks, including Hitchcock Park, which features open green spaces and interconnected walking and biking paths suitable for running or leisure cycling.

Sources
Arts and culture

Mitchell's cultural landscape is anchored by the world-famous Corn Palace, an active arena and civic venue redecorated annually with murals crafted from corn and grains, which also hosts events like the Corn Palace Stampede rodeo. History and regional art thrive at the Mitchell Prehistoric Indigenous Archaeological Site & Museum, where visitors can view an active archeodome dig, alongside the Dakota Discovery Museum, the McGovern Legacy Museum, and the Carnegie Resource Center.

Downtown also features independent specialty shops such as Atomik Komics and Q Jewelry.

Sources
Seasons and weather

Mitchell experiences dramatic seasonal shifts typical of the Northern Plains. Winters are long and harsh, bringing sub-zero temperatures, intense windchills, and drifting snow that can lead to whiteout driving conditions.

Spring brings a thawing transition into warm, sunny summers ideal for lake recreation, followed by crisp, clear autumn months before cold weather returns in late fall.

Sources
For families

Families in Mitchell have access to public education through the Mitchell School District, including Gertie Belle Rogers Elementary, Longfellow Elementary, L.B. Williams Elementary, and Mitchell Middle School. The town offers a safe, low-noise environment with numerous neighborhood playgrounds, community sporting events, and cultural programming at local museums that cater well to raising children in a close-knit setting.

Sources
What locals say

Residents appreciate Mitchell for its friendly Midwestern neighborliness, slow-paced environment, and exceptionally calm surroundings. However, locals and newcomers caution that life on the plains can feel isolated, with limited big-box retail and nightlife compared to larger hubs.

Community discussions also highlight that brutal winter storms, biting winds, and the quiet rhythm require an adjustment for those accustomed to larger metropolitan areas.

Sources

Other cities