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Nursing Mastery

78 nursing jobs in Sioux Falls, SD

Sioux Falls blends Midwestern friendliness with urban energy. South Dakota's largest city offers a growing healthcare sector, clean parks along the Big Sioux River, and a vibrant downtown. Nurses enjoy no state income tax, short commutes, and genuine community in this steadily expanding metro.

Pay and living in Sioux Falls

Map showing the location of Sioux Falls, SD
Sioux Falls, SD on the map · © Mapbox © OpenStreetMap· Open the live map
Avera Health workplace
Avera Health — a workplace named in a current Sioux Falls postingView Avera Health

Find a nursing job in Sioux Falls

Hiring here: Sanford Health (25) · Veterans Health Administration (19) · Good Samaritan (4) · Avera (3) · Avera Health (3) · Sioux Center Health (2)

  • RN
  • 8-hour days
Apply
Avera workplace
  • RN
  • Day shift
Apply
A photo of My Marijuana Cards

Sioux Falls APRN Medical Cannabis Industry

$50/hr

My Marijuana Cards logoMy Marijuana Cards

Sioux Falls, SD

  • APRN
Apply
  • RN
  • 12-hour rotating
Apply
  • RN
  • Day shift
  • Per diem
Apply

Registered Nurse (RN) | Comprehensive Pain Clinic

$28/hr

Avera Health logoAvera Health

Sioux Falls, SD

  • RN
  • 10-hour days
  • Tuition reimbursement
Apply
  • RN
Apply

Registered Nurse - Patient Safety Informatics

$43/hr

Veterans Health Administration · Health system employer

Sioux Falls, SD · Posted yesterday

  • New grads welcomed
  • RN
  • Monday - Friday 7:30am - 4:00pm and 8:00am - 4:30pm
  • Compact license OK
Apply

Registered Nurse (NIGHT SHIFT ONLY)(SDSP)

$33/hr

South Dakota State Government

Sioux Falls, SD

  • Sign-on bonus
  • RN
  • Night shift
  • Compact license OK
Apply

LPN - Full Time PMs - SF Village

$31/hr

Good Samaritan

Sioux Falls, SD · Posted last week

  • Sign-on bonus
  • LPN
  • 8-hour evenings
  • Compact license OK
Apply

RN Traveler - Sioux Falls Surge Renal

$2,760/week

Solutions by Sanford logoSolutions by Sanford

Sioux Falls, SD · Posted last week

  • RN
  • 12-hour nights
  • Travel contract
Apply

Registered Nurse - Nights

$41.00–$45.00

Correctional Medical Management, LLC

Sioux Falls, SD

  • RN
  • 12-hour nights
Apply

RN / LPN

$29/hr

PorchLight Services

Sioux Falls, SD

  • RN
  • 8-hour 8 hour
Apply

Registered Nurse (DAY SHIFT ONLY) (SDSP)

$33/hr

State of South Dakota

Sioux Falls, SD · Posted 2 weeks ago

  • Sign-on bonus
  • NP
  • Day shift
  • Compact license OK
Apply

School Nurse - 1.0 FTE

$28/hr

Sioux Falls School District logoSioux Falls School District

Sioux Falls, SD

  • RN
  • 8-hour days
Apply

Registered Nurse I

Turnwell Mental Health Network INC logoTurnwell Mental Health Network INC · Health system employer

Sioux Falls, SD

  • RN
  • Weekend shift
  • Per diem
Apply
  • RN
Apply

Registered Nurse

Davita logoDavita

Sioux Falls, SD

  • RN
  • Rotating shift
Apply

RN Telephone Triage (Work from Home)

TeamHealth logoTeamHealth

Sioux Falls, SD

  • RN
  • Evening shift
  • Per diem
Apply

Registered Nurse (RN) | Navigator

$36/hr

Sioux Center Health logoSioux Center Health · Health system employer

Sioux Falls, SD · Posted last week

  • RN
  • Day shift
Apply

Registered Nurse

$35/hr

City of Sioux Falls

Sioux Falls, SD · Posted last week

  • Sign-on bonus
  • RN
Apply

RN, ICU

$63/hr

Genie Healthcare

Sioux Falls, SD

  • RN
  • 12-hour nights
  • Travel contract
Apply

Registered Nurse - Intensive Care Unit

$45/hr

US Veterans Health Administration

Sioux Falls, SD

  • RN
  • Rotating shift
  • Travel contract
  • Union represented
Apply
  • RN
  • Day shift
  • Travel contract
Apply

Registered Nurse - RN - Pulmonary Clinic

$37/hr

Sanford Health logoSanford Health

Sioux Falls, SD · Posted last week

  • RN
  • 8-hour days
  • Compact license OK
Apply

LPN LTC

$1,340/week

Talented Medical Solutions logoTalented Medical Solutions · Staffing partner

Sioux Falls, SD · Seen active 2 days ago

  • LPN
  • 12-hour days
  • Travel contract
Apply

Registered Nurse / RN OR

$3,050/week

Prime Time Healthcare logoPrime Time Healthcare · Staffing partner

Sioux Falls, SD

  • RN
  • 8-hour days
  • Travel contract
Apply

RN - Outpatient Clinic

$2,940/week

Vibra Travels LLC logoVibra Travels LLC · Staffing partner

Sioux Falls, SD

  • RN
  • Travel contract
Apply

RN Clinic

$2,300/week

TNAA Healthcare logoTNAA Healthcare · Staffing partner

Sioux Falls, SD

  • RN
  • Travel contract
Apply

Registered Nurse - Associate Director, Patient Care Services/Nurse Executive

$91/hr

Veterans Health Administration

Sioux Falls, SD

  • RN
Apply

Registered Nurse (STRAIGHT WEEKEND NIGHT SHIFT) (SDSP)

$36/hr

South Dakota State Government

Sioux Falls, SD

  • Sign-on bonus
  • RN
  • Night shift
  • Compact license OK
Apply

RN - Full Time Days Weekends - SF Center

$34/hr

Good Samaritan

Sioux Falls, SD

  • Sign-on bonus
  • RN
  • 12-hour days
  • Compact license OK
Apply

RN Traveler - Solutions by Sanford - Sioux Falls Cardiology

$2,760/week

Solutions by Sanford logoSolutions by Sanford

Sioux Falls, SD

  • RN
  • Rotating shift
  • Compact license OK
Apply

RN - Outpatient Services | Avera Heart Hospital

Sioux Center Health logoSioux Center Health · Health system employer

Sioux Falls, SD · Posted 2 weeks ago

  • RN
  • 12-hour days
  • Compact license OK
Apply

Licensed Practical Nurse - LPN - Dermatology Clinic

$26/hr

Sanford Health logoSanford Health

Sioux Falls, SD · Posted last week

  • LPN
  • Day shift
  • Compact license OK
Apply

Registered Nurse - Informaticist

$43/hr

Veterans Health Administration · Health system employer

Sioux Falls, SD · Posted yesterday

  • New grads welcomed
  • RN
  • Monday - Friday 7:30am - 4:00pm and 8:00am - 4:30pm
Apply

RN - Full Time Nights - SF Village

$34/hr

Good Samaritan

Sioux Falls, SD

  • Sign-on bonus
  • RN
  • Night shift
Apply

LPN or MA - Hospice - PRN

$29/hr

Sanford Health logoSanford Health

Sioux Falls, SD · Posted last week

  • LPN
  • Ratio 1:4
  • 12-hour shifts
Apply

Nursing Assistant- Inpatient Specialty Care

$24/hr

Veterans Health Administration · Health system employer

Sioux Falls, SD · Posted last week

  • Floating required
Apply

Rehab RN - Full Time Weekend Nights - SF Village

$34/hr

Good Samaritan

Sioux Falls, SD

  • Sign-on bonus
  • RN
  • Night shift
Apply

Medical Assistant - LPN - Orthopedics & Sports Medicine

$24/hr

Sanford Health logoSanford Health

Sioux Falls, SD · Posted last week

  • LPN
  • 8-hour varied
  • Compact license OK
Apply

Nursing Assistant- Specialty Care

$24/hr

Veterans Health Administration · Health system employer

Sioux Falls, SD · Seen active last week

  • New grads welcomed
  • Rotating shift
Apply

Registered Nurse - Surgical Trauma - Rotating

$40/hr

Sanford Health logoSanford Health

Sioux Falls, SD · Posted last week

  • New grads welcomed
  • RN
  • 12-hour rotating
  • Compact license OK
Apply

Registered Nurse - Nurse Manager

$50/hr

Veterans Health Administration · Health system employer

Sioux Falls, SD

  • RN
Apply

Sanford Health

4 open roles · Permanent

Registered Nurse - Surgical Trauma - Nights

$32.00–$48.00

Sioux Falls, SD · Posted last week

  • New grads welcomed
  • RN
  • 12-hour nights
  • Compact license OK
Apply
  • New grads welcomed
  • RN
  • 12-hour rotating
  • Compact license OK
Apply

LPN - Licensed Practice Nurse - Surgical Associates

$21.75–$29.50

Sioux Falls, SD · Posted 2 weeks ago

  • LPN
  • 8-hour days
  • Compact license OK
Apply
  • LPN
  • Day shift
  • Compact license OK
Apply

Working and living in Sioux Falls

· 78 open roles in this snapshot

Posted hourly pay

RN
$32/hr median
$32$33/hr middle half · 21 postings
LPN
$22/hr median
$19$22/hr middle half · 9 postings

See roles with listed pay

Living costs

Metro price level
90.6 (100 = national)
BEA 2024
Median gross rent
$1,035/mo
Rent and tenant-paid utilities
Median household income
$75,970/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

13 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

7 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • NP1
  • APRN1
  • RN62
  • LPN12
  • LVN1

One posting may accept more than one credential.

Shifts listed

  • Days34
  • Nights11
  • Rotating9
  • Evenings2
  • weekend1
  • per-diem1

Postings may list several shifts or leave the shift unspecified.

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