Skip to content

112 nursing jobs in Buffalo, NY

Anchored by the bustling Buffalo Niagara Medical Campus, Buffalo pairs top-tier healthcare systems with authentic Rust Belt charm. Unwind along Elmwood Village's tree-lined avenues, explore historic Allentown, or catch Lake Erie sunsets. With living costs about 4% below the national average, the City of Good Neighbors lets nurses build a thriving career without sacrificing financial breathing room.

Buffalo, NY on the map· Open the live map
Erie County Medical Center Corporation workplace
Erie County Medical Center Corporation — a workplace named in a current Buffalo postingView Erie County Medical Center Corporation →

Find a nursing job in Buffalo

Hiring here: Veterans Health Administration (43) · Catholic Health System (13) · Veterans Health Administration (6) · Kaleida Health (5) · Roswell Park Cancer Institute (5) · White Glove Placement New York (5)

Erie County Medical Center Corporation

Buffalo, NY

  • LPN
  • FT - Evening Shift
1 / 2

Registered Nurse (RN) Supervisor Weekends

Ellicott Center logoEllicott Center

Buffalo, NY

$50/hr

  • Sign-on bonus
  • RN
  • Weekend shift
1 / 2

Licensed Practical Nurse

Roswell Park Comprehensive Cancer Center

Buffalo, NY · Posted 3 days ago

$27–$28/hr

  • LPN
1 / 2

Full Time, Part-Time or Per Diem RN (Salaried)

Midwifery at the Coit House

Buffalo, NY

$45–$50/hr

  • RN
  • Per diem
  • CEU allowance
1 / 2

Nurse II - Therapeutic Apheresis (Full Time/Temporary-Benefited)

Roswell Park Cancer Institute logoRoswell Park Cancer Institute

Buffalo, NY

$47/hr

  • RN
  • Day shift
1 / 2

Charge Nurse

Sisters of Mercy of the Americas logoSisters of Mercy of the Americas

Buffalo, NY

$27–$35/hr

  • LPN
  • Per diem

Erie County Medical Center Corporation

Buffalo, NY

  • LPN
  • Night shift

Roswell Park Comprehensive Cancer Center

Buffalo, NY

  • LPN
  • Evening shift
  • 6 East
Roswell Park Cancer Institute logo

Roswell Park Cancer Institute

Buffalo, NY

  • NP/RN
  • Day shift

Erie County Medical Center Corporation

Buffalo, NY

  • New grads welcomed
  • LPN
  • Evening shift
  • Long-Term Care Facility
Roswell Park Cancer Institute logo

Roswell Park Cancer Institute

Buffalo, NY

  • RN
  • Day shift

Erie County Medical Center Corporation

Buffalo, NY

Licensed Practical Nurse LTC - RPT- Day Shift

Posted 2 weeks ago

$29–$39/hr

  • LPN
  • Day shift
Roswell Park Cancer Institute logo

Roswell Park Cancer Institute

Buffalo, NY

  • RN
  • Night shift
  • ADN accepted
Roswell Park Cancer Institute logo

Roswell Park Cancer Institute

Buffalo, NY

Case Manager

$40–$48/hr

  • RN
  • Day shift
  • +$8.48/hr differential
Catholic Health System logo

Catholic Health System

Buffalo, NY · Health system employer

  • RN
  • Per diem

OWM Integrative Wellness

Buffalo, NY

Part-Time Infusion Nurse

Posted last week

$40–$44/hr

  • RN
  • 10-⁠hour rotating
  • ADN accepted

Hospice & Palliative Care Buffalo

Buffalo, NY

  • RN
  • 10-⁠hour days
  • Tuition reimbursement
Buffalo Center logo

Buffalo Center

Buffalo, NY

MDS Coordinator

$100,000–$110,000/year

  • Sign-on bonus
  • RN
Kaleida Health logo

Kaleida Health

Buffalo, NY

Licensed Practical Nurse - Broadway

Posted last week

$31–$39/hr

  • LPN
  • Day shift
Visiting Nursing Association of Western New York logo

Visiting Nursing Association of Western New York

Buffalo, NY

  • RN
  • Day shift
  • Tuition reimbursement
NurseAmerica, Inc. logo

NurseAmerica, Inc.

Buffalo, NY

  • RN
  • 12-⁠hour nights
  • Travel contract

Child and Family Services

Buffalo, NY

  • LPN
  • 9AM-5PM Monday through Friday
  • outpatient mental health clinic

New York State Department of Civil Service

Buffalo, NY

  • RN
  • Monday through Friday

Avante Care Management

Buffalo, NY

RN

$50–$55/hr

  • Sign-on bonus
  • RN
  • Per diem

UB Neurosurgery, Inc

Buffalo, NY

Registered Nurse (RN)

$70,000–$80,000/year

  • RN
  • Day shift
Atlas Surgery Center logo

Atlas Surgery Center

Buffalo, NY

  • RN
  • Day shift
Kedrion Biopharma logo

Kedrion Biopharma

Buffalo, NY

  • RN
Kedplasma logo

Kedplasma

Buffalo, NY

  • RN
Tang and Company logo

Tang and Company

Buffalo, NY

  • RN
  • Day shift
  • Per diem

Immigration and Customs Enforcement

Buffalo, NY

Clinical Nurse Manager (O-6 Billet) Supervisory

Posted last week

Up to $150,000/year

  • RN

Veterans Health Administration

Buffalo, NY · Health system employer

  • RN
WorkFit Medical Staffing, PLLC logo

WorkFit Medical Staffing, PLLC

Buffalo, NY · Staffing partner

  • RN
  • Travel contract

White Glove Placement New York

Buffalo, NY · Staffing partner

  • RN
  • Travel contract

WorkFit Medical Staffing

Buffalo, NY · Staffing partner

RN - ICU

From $62/hr

  • RN
  • Night shift
  • Per diem

Catholic Health System

Buffalo, NY · Health system employer

  • RN
  • Day shift
  • Agency contract
Buffalo Center logo

Buffalo Center

Buffalo, NY

  • Sign-on bonus
  • RN
  • Rotating shift
Kaleida Health logo

Kaleida Health

Buffalo, NY

  • RN
  • 7p-7:30a
  • BGMC Nursing 9S

Catholic Health System

Buffalo, NY · Health system employer

  • RN
  • 12-⁠hour days
  • ADN accepted
Kaleida Health logo

Kaleida Health

Buffalo, NY

  • LPN
  • Scheduled Work Hours: Variable
  • Per diem

Catholic Health System

Buffalo, NY · Health system employer

  • New grads welcomed
  • RN
  • 12-⁠hour nights
Kaleida Health logo

Kaleida Health

Buffalo, NY

  • RN
  • Rotating shift

Catholic Health System

7 open roles

Registered Nurse 3 South SCH

Buffalo, NY · Posted last week

$42–$58/hr

  • RN
  • 12-⁠hour nights
  • LPN
  • 8-⁠hour evenings
  • SNF Post Acute
  • LPN
  • 3pm-11pm

Registered Nurse Lactation SCH

Buffalo, NY

$42–$58/hr

  • RN
  • 12-⁠hour nights
  • Per diem

Registered Nurse Lactation SCH

Buffalo, NY

$42–$58/hr

  • RN
  • Rotating shift
  • Per diem

Registered Nurse Lactation SCH

Buffalo, NY

$42–$58/hr

  • RN
  • 12-⁠hour days
  • RN
  • 8-⁠hour days
  • Per diem

Working and living in Buffalo

· 112 open roles

Posted hourly pay

RN
$42/hr median
$41–$47/hr middle half · 29 postings
LPN
$27/hr median
$27–$30/hr middle half · 12 postings

See roles with listed pay

Living costs

Metro price level
95.8 (100 = national)
BEA 2024
Median gross rent
$1,046/mo
Rent and tenant-paid utilities
Median household income
$50,041/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

12 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

8 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • NP1
  • APRN2
  • RN88
  • LPN17
  • LVN3

One posting may accept more than one credential.

Shifts listed

  • Days31
  • Nights23
  • Rotating13
  • per-diem8
  • Evenings5
  • weekend1

Postings may list several shifts or leave the shift unspecified.

Living in Buffalo

Buffalo is a mid-size Lake Erie city where an $80k–$150k nurse can still buy a colorful Victorian, walk to wings and a brewery, and cross town in twenty minutes.

More about life here

Healthcare sits on the Buffalo Niagara Medical Campus and Roswell Park. Elmwood Village and Allentown are the young-professional cores—Elmwood Avenue shops, Allen Street murals—while Parkside hugs Olmsted’s Delaware Park and Williamsville and Clarence offer the safest schools.

Food runs from Gabriels Gate and Bar-Bill wings and Charlie the Butcher’s beef on weck to Southern Junction’s James Beard-nominated barbecue, Remedy House coffee, 35-plus breweries, and 4 a.m. last call. Canalside, the Outer Harbor, and Erie Basin Marina mean kayaks, concerts, and winter skating; Niagara Falls and Toronto are day trips.

Tradeoffs are real: lake-effect winters, high New York taxes, weak transit and city parking, city schools that lag the Northtowns, and a redlining map still visible by neighborhood.

Sources
As of Sep 11, 2026
Neighborhoods

Nurses and young professionals most often land in Elmwood Village or Allentown in the city, or the Northtowns if they want yards and schools. Elmwood Village is the walkable spine of restaurants, cafes, bars, and independent shops along Elmwood Avenue, with summer festivals and parades; 2026 figures put median homes around $325,714 and rent near $920. Allentown, just north of downtown, is the LGBTQ-friendly arts neighborhood of brightly painted Victorian, Italianate, and Queen Anne houses, murals, and late-night Allen Street (median home $257,525, rent $716).

Parkside/Park Meadow is calmer and family-oriented beside Olmsted’s Delaware Park and Wright’s Darwin Martin House (~$268,100 / $1,037 rent). Reddit and Facebook repeatedly name Williamsville and Clarence as the safe, high-school-quality suburbs; Tonawanda ($119,100 / $697) and West Seneca ($157,400 / $875) are the cheaper suburban plays.

North Buffalo and South Buffalo also come up as historic, buyable city neighborhoods.

Sources
Housing

Buying is still the affordability story: a local realtor cites a median home around $241,500, while Extra Space’s 2026 neighborhood medians run from Tonawanda at $119,100 to Elmwood Village at $325,714. Typical stock is historic—Victorian, Italianate, and Queen Anne houses in Allentown and Elmwood, calmer homes by Delaware Park, suburban options in West Seneca and Tonawanda. Highlighted rents run roughly $697–$1,037 a month.

The market is described as competitive and somewhat rental-favoring; utilities and car insurance run higher than in many states, and New York property and income taxes take a bite that sticker prices do not show.

Sources
Getting around

Residents say you can drive across Buffalo in about twenty minutes without big-city gridlock, and the road system is generally well regarded, but a reliable car is treated as a necessity—especially in snow. Public transit is described as limited and spread out, the metro is not highly rated, and street parking inside the city is a frequent complaint.

Healthcare employment is anchored by the Buffalo Niagara Medical Campus and Roswell Park Comprehensive Cancer Center. Sources do not name specific bus or rail lines to those campuses.

Sources
Food and dining

The city’s food identity still starts with wings and beef on weck—Gabriels Gate in Allentown is widely named for wings, Bar-Bill Tavern for authentic Buffalo wings, and Charlie the Butcher on the classic food trail—then opens into a chef-driven scene. Southern Junction, a James Beard-nominated restaurant, infuses southern barbecue with Indian flavors.

Elmwood Avenue and Allentown’s Allen Street are the densest strips of restaurants, cafes, and bars; Remedy House is a named coffee stop and Hydraulic Hearth a patio landmark. Count on 35-plus breweries and five-plus distilleries, a growing cocktail (and mocktail) bar culture, farmers markets, food trucks, and last call at 4 a.m., which matters after a late shift.

Sources
Outdoors

Delaware Park, designed by Frederick Law Olmsted (the same landscape architect as Central Park), is the city’s backyard and the reason Parkside exists; the Buffalo Zoo and Frank Lloyd Wright’s Darwin Martin House sit nearby. The reimagined Lake Erie waterfront—Canalside, the Outer Harbor, and Erie Basin Marina—supports kayaking, biking, summer concerts, and winter skating plus heated igloos.

Boat tours run the Buffalo River’s industrial-to-waterfront story. Niagara Falls is the easy regional day trip, and residents cite plentiful parks and outdoor time as a core reason they stay.

Sources
Arts and culture

Allentown is the artistic heart: murals, colorful houses, Visioning Workshops, the Allen West Festival, and nightlife that runs late on Allen Street. Elmwood Village hosts summer events, festivals, and parades along Elmwood Avenue.

The Buffalo AKG Art Museum anchors a contemporary arts scene; Music is Art fills Terminal B on the waterfront. Architecture is everyday culture—Wright’s Darwin Martin House, preserved downtown landmarks, and Victorian streetscapes.

Sports and live music are cited as part of daily life; nightlife is tavern- and brewery-heavy rather than a major club scene, with last call at 4 a.m.

Sources
Seasons and weather

Winter is the tradeoff everyone names: lake-effect snow, ice, sub-zero stretches, and a season that can feel long and dark, with real shoveling. One 2026 city guide also cites about 25 inches of seasonal snow alongside lake-effect weather.

Summer is when the city comes alive—Canalside waterfront festivals, outdoor concerts, neighborhood farmers markets, kayaking and biking the Outer Harbor. Fall and spring complete four distinct seasons; snow melts every year, and the waterfront stays programmed in winter with skating and heated igloos.

Newcomers are told the weather risk is snow, not hurricanes or major tornadoes.

Sources
For families

For kids, Reddit points to the Northtowns: Williamsville and Clarence for the best schools, nicest neighborhoods, and a very safe feel. Park Meadow is explicitly family-friendly and next to Delaware Park.

Suburban schools are called amazing while city schools are not nearly as good, though a New York State diploma is the same credential. Buffalo overall is cited as 11% safer than other New York cities, with residents saying crime is real but limited to a few areas.

Allentown is marketed to families as well as students and young professionals, but its crime note—safer than only 9% of New York cities—is a caution versus the Northtowns.

Sources
What locals say

Locals call it the City of Good Neighbors: a smaller big city with friendly people, a low cost of living, strong food-and-beer culture, and proximity to Toronto and Niagara Falls, plus four seasons without hurricanes or tornadoes. The downsides come up just as often—lake-effect winters that feel long, dark, and shovel-heavy; high New York income and property taxes; a bar-centric rather than club nightlife; tough city parking and weak transit; and a visible redlining legacy (West Side Hispanic, East Side African American, North Italian, South Buffalo Irish and Polish, suburbs majority white).

Crime is described as real but concentrated in a few areas; city schools lag the suburbs.

Sources

Other cities