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68 nursing jobs in Biloxi, MS

In Biloxi, your nursing career pairs with breezy Gulf Coast living along Highway 90. Trade hectic commutes for white-sand beaches, fresh-caught Gulf shrimp, and coastal porch life. With a cost of living 10% below the national average, your paycheck stretches further while you care for Mississippi’s warm, close-knit seaside communities.

Biloxi, MS on the map· Open the live map
The Pillars workplace
The Pillars — a workplace named in a current Biloxi postingView The Pillars →

Find a nursing job in Biloxi

Hiring here: Memorial Hospital at Gulfport (33) · Veterans Health Administration (22) · Centerwell (2) · Enhabit Home Health & Hospice (2) · The Pillars (2) · University of Mississippi Medical Center (2)

The Pillars logo

The Pillars

Biloxi, MS

  • RN
  • 8-⁠hour days
1 / 2

Assistant Director of Wellness FT

The Blake at Biloxi logoThe Blake at Biloxi

Biloxi, MS

$56,000–$58,000/year

  • LPN
  • Rotating shift
1 / 2

Unit Coordinator/Educator - Med Surg - Day - FT - Biloxi Location

Memorial Hospital at Gulfport

Biloxi, MS · Posted today

  • RN
  • Day shift
1 / 3

RN I-PRN-Ambulatory

University of Mississippi Medical Center

Biloxi, MS · Posted 3 days ago

  • RN
  • Day shift
  • Per diem

Memorial Hospital at Gulfport

Biloxi, MS

  • LPN
  • Day shift

University of Mississippi Medical Center

Biloxi, MS

  • LPN
Memorial Hospital at Gulfport workplace

Memorial Hospital at Gulfport

32 open roles

  • RN
  • Night shift
  • Per diem
  • RN
  • Night shift
  • Per diem
  • Day shift
  • RN
  • Night shift
  • RN
  • Day shift
  • Per diem
  • RN
  • Night shift
  • Per diem
  • RN
  • Night shift
  • RN
  • Rotating shift
  • Per diem
  • RN
  • Night shift
  • RN
  • Day shift
  • RN
  • Night shift
  • RN
  • Night shift
  • Per diem
  • RN
  • Day shift
  • RN
  • Night shift
  • RN
  • Night shift
  • Per diem
  • RN
  • Day shift
  • LPN
  • Day shift
  • Per diem
  • RN
  • Rotating shift
  • Per diem
  • RN
  • Day shift
  • RN
  • Rotating shift
  • Per diem
Arden Home Health and Hospice logo

Arden Home Health and Hospice

Biloxi, MS

  • LPN/LVN
  • Per diem
Oceans Healthcare logo

Oceans Healthcare

Biloxi, MS · Health system employer

Registered Nurse RN Days

Posted 5 days ago

  • RN
Centerwell logo

Centerwell

Biloxi, MS

Clinical Care Nurse (RN)

$64,000–$88,000/year

  • RN
  • 8-⁠hour days
  • ADN accepted

Veterans Health Administration

Biloxi, MS · Health system employer

Advanced Practice Nurse-Deputy Chief

$152,000–$203,000/year

  • NP
Brookdale Senior Living Inc. logo

Brookdale Senior Living Inc.

Biloxi, MS

LPN or LVN

Posted last week

  • LPN/LVN
Enhabit Home Health & Hospice logo

Enhabit Home Health & Hospice

Biloxi, MS

RN - Hospice

Posted last week

  • RN
Centerwell logo

Centerwell

Biloxi, MS

LPN/LVN

$44,000–$60,000/year

  • LPN/LVN

Veterans Health Administration

Biloxi, MS · Health system employer

  • New grads welcomed
  • APRN
  • 8-⁠hour days

Veterans Health Administration

Biloxi, MS · Health system employer

Registered Nurse - Assistant Nurse Manager

Closes Mon

$67,000–$161,000/year

  • RN

Working and living in Biloxi

· 68 open roles

Living costs

Metro price level
90.0 (100 = national)
BEA 2024
Median gross rent
$1,089/mo
Rent and tenant-paid utilities
Median household income
$57,204/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

10 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

9 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • NP1
  • APRN1
  • RN54
  • LPN10
  • LVN5

One posting may accept more than one credential.

Shifts listed

  • Days26
  • Nights17
  • Rotating6
  • per-diem4

Postings may list several shifts or leave the shift unspecified.

Living in Biloxi

Biloxi offers healthcare professionals a distinctive Gulf Coast setting shaped by its peninsular geography, nestled between the Mississippi Sound and the Back Bay.

More about life here

Known for Keesler Air Force Base and a bustling resort economy, the city pairs everyday coastal living with high-energy amenities. Off-shift nurses can explore cultural anchors like the Frank Gehry-designed Ohr-O'Keefe Museum of Art, catch minor league Biloxi Shuckers baseball, or sample fresh Gulf catch at Mary Mahoney's Old French House and Half Shell Oyster House.

Housing spans elevated post-Katrina cottages in historic Point Cadet, beachfront condominiums along Highway 90, and quieter inland subdivisions across the Popps Ferry bridge or in adjacent communities like D'Iberville and Ocean Springs. Commutes are relatively light via Interstate 110, though private vehicles are essential.

Relocating clinicians must weigh genuine coastal tradeoffs: oppressive summer humidity, coastal hurricane exposure, and the mandatory expense of flood and windstorm insurance for low-lying properties. For those drawn to water access, rich seafood traditions, and mild winters, Biloxi delivers a uniquely relaxed coastal lifestyle.

Sources
As of Sep 16, 2026
Neighborhoods

Point Cadet on the eastern peninsula features historic cottages, elevated post-Katrina builds, and waterfront condos with walkability to the harbor and casinos, though flood insurance demands attention. Back Bay offers a more residential, working-community atmosphere favored by locals and boaters seeking water and canal access off the tourist strip.

North Biloxi, reached across the Popps Ferry bridge, along with nearby communities like D'Iberville, St. Martin, and Ocean Springs, provide quieter suburban subdivisions and accessible commutes onto the main peninsula via Interstate 110.

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Housing

Housing stock varies widely by geographic positioning on the peninsula. The Highway 90 beachfront corridor is dominated by high-rise and mid-rise condominiums, where buyers and renters must evaluate steep HOA fees and insurance structures.

Historic cottages and elevated pilings characterize Point Cadet, while Back Bay provides more affordable single-family houses with canal or bay access, and inland subdivisions north of Popps Ferry offer traditional suburban layouts.

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Getting around

Personal vehicles are the primary mode of travel across Biloxi, as regional public transit options are quite limited. Drivers navigate the peninsula via Highway 90 along the Gulf coast and Interstate 110 connecting north toward Interstate 10, with the Popps Ferry bridge serving as a vital link to northern residential pockets.

Commuting traffic is generally moderate outside of tourist weekends and casino corridor congestion along Highway 90.

Sources
Food and dining

Biloxi's food scene blends classic Gulf-to-table seafood with casino-anchored fine dining. Well-known culinary staples include Mary Mahoney's Old French House, Half Shell Oyster House, White Pillars, and BR Prime at the Beau Rivage.

For more casual dining and bites, locals frequent Woody's Roadside, Patio 44, Ole Biloxi Fillin Station, Parrain's Jambalaya Kitchen, and Greenhouse on Porter.

Sources
Outdoors

Outdoor recreation centers heavily on the water, featuring Biloxi Beach along the Mississippi Sound and paddling or boating excursions to uninhabited Deer Island. Anglers take advantage of boat launches in Back Bay Biloxi and the small-craft harbor, while walkers and runners frequently cross the pedestrian path on the Biloxi Bay Bridge.

Scenic beachside parks and charter trips on historic Biloxi Schooners provide year-round coastal access.

Sources
Arts and culture

Cultural life in Biloxi combines coastal heritage with major entertainment venues. Landmarks include the Frank Gehry-designed Ohr-O'Keefe Museum of Art, the Maritime & Seafood Industry Museum, and the historic Biloxi Lighthouse.

Live shows and major concerts headline at the Mississippi Coast Coliseum and resort venues like Sapphire Supper Club or Ground Zero Blues Club, while minor league baseball fans catch Biloxi Shuckers games downtown.

Sources
Seasons and weather

The local climate features mild, temperate winters that allow for outdoor recreation without freezing conditions. Summers, however, bring intense heat paired with oppressive coastal humidity that newcomers must adapt to.

The warmer months through early autumn also coincide with the Atlantic hurricane season, requiring vigilance, storm readiness, and occasional tropical weather disruptions.

Sources
For families

Relocating families often balance peninsula convenience against suburban school zones. Neighborhoods across the Back Bay in D'Iberville, St. Martin, and neighboring Ocean Springs are frequently highlighted by local agents and parents for family-friendly subdivisions and community amenities.

Keesler Air Force Base lends a steady military family presence to the broader community, though public school performance and resources vary noticeably across district boundaries.

Sources
What locals say

Residents praise Biloxi for its laid-back coastal lifestyle, friendly community, rich seafood heritage, and vibrant casino entertainment. On the other hand, locals routinely point out that coastal living carries high wind and flood insurance requirements, seasonal hurricane exposure, sweltering summer humidity, and an economy heavily tied to tourism and hospitality.

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