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38 nursing jobs in Tupelo, MS

Tupelo, Mississippi, blends small-town warmth with unexpected cultural depth as the birthplace of Elvis Presley. Nurses relocating here will find affordable living, friendly communities, and a relaxed pace ideal for raising a family or starting fresh in the Magnolia State.

Tupelo, MS on the map· Open the live map
North Mississippi Medical Center workplace
North Mississippi Medical Center — a workplace named in a current Tupelo postingView North Mississippi Medical Center →

Find a nursing job in Tupelo

Hiring here: Diversicare of Tupelo, LLC (12) · North Mississippi Medical Center (12) · North Mississippi Health Services (4) · North Mississippi Medical Center (3) · University of Mississippi Medical Center (3) · Fresenius Medical Care (2)

North Mississippi Medical Center logo

North Mississippi Medical Center

Tupelo, MS

  • RN
  • PRN - Variable
  • Per diem
1 / 3

Neonatal NP - Tupelo - Department of Pediatrics

University of Mississippi Medical Center

Tupelo, MS · Posted last week

  • NP
  • Rotating shift
North Mississippi Medical Center logo

North Mississippi Medical Center

Tupelo, MS

  • RN
  • Day shift
  • Compact license OK

University of Mississippi Medical Center

Tupelo, MS

  • NP
  • Rotating shift
North Mississippi Medical Center logo

North Mississippi Medical Center

Tupelo, MS

  • RN
  • Per diem
  • Compact license OK

University of Mississippi Medical Center

Tupelo, MS

  • NP
  • Day shift
North Mississippi Medical Center logo

North Mississippi Medical Center

Tupelo, MS

  • RN
  • Day shift
  • Compact license OK

Diversicare of Tupelo, LLC

Tupelo, MS

Unit Manager RN

Posted last week

  • RN

North Mississippi Health Services

Tupelo, MS

  • LPN
  • Night shift
  • Agency contract

North Mississippi Medical Center

Tupelo, MS

  • RN
  • Day shift
  • Per diem
Vitality Living logo

Vitality Living

Tupelo, MS

  • LPN/LVN
  • Day shift
Oceans Healthcare logo

Oceans Healthcare

Tupelo, MS · Health system employer

  • RN
  • 12-⁠hour nights
  • Per diem
Fresenius Medical Care logo

Fresenius Medical Care

Tupelo, MS

  • New grads welcomed
  • RN

Diversicare of Tupelo, LLC

Tupelo, MS

LVN LPN - New WAGE SCALE

Posted yesterday

  • Sign-on bonus
  • LPN/LVN

North Mississippi Health Services

Tupelo, MS

  • LPN
  • Day shift
  • Tuition reimbursement

North Mississippi Medical Center

Tupelo, MS

  • RN
  • Day shift
  • Compact license OK
Fresenius Medical Care logo

Fresenius Medical Care

Tupelo, MS

  • RN

Diversicare of Tupelo, LLC

Tupelo, MS

Unit Manager RN

Posted 4 days ago

  • RN

North Mississippi Health Services

Tupelo, MS

  • LPN
  • Day shift
  • Tuition reimbursement

North Mississippi Medical Center

Tupelo, MS

  • RN
  • Day shift
  • Agency contract

Diversicare of Tupelo, LLC

Tupelo, MS

Treatment Nurse - RN

Posted 5 days ago

  • RN
  • Day shift

North Mississippi Health Services

Tupelo, MS

  • Sign-on bonus
  • RN
  • Day shift
  • Agency contract
North Mississippi Medical Center logo

North Mississippi Medical Center

Tupelo, MS

  • RN
  • Day shift
  • SURGERY CENTER JOINT VENTURE

Diversicare of Tupelo, LLC

Tupelo, MS

LVN LPN

Posted 5 days ago

  • LPN/LVN
North Mississippi Medical Center logo

North Mississippi Medical Center

Tupelo, MS

  • RN
  • Day shift
  • Compact license OK

Diversicare of Tupelo, LLC

Tupelo, MS

RN Nursing Supervisor

Posted 5 days ago

  • RN
North Mississippi Medical Center logo

North Mississippi Medical Center

Tupelo, MS

  • RN
  • Night shift
  • Compact license OK

Diversicare of Tupelo, LLC

Tupelo, MS

Nurse RN

Posted 5 days ago

  • Sign-on bonus
  • RN
North Mississippi Medical Center logo

North Mississippi Medical Center

Tupelo, MS

  • New grads welcomed · reported
  • RN
  • Night shift
  • Compact license OK

Diversicare of Tupelo, LLC

Tupelo, MS

Treatment Nurse - RN

Posted last week

  • RN
  • Day shift
North Mississippi Medical Center logo

North Mississippi Medical Center

Tupelo, MS

  • RN
  • Day shift
  • Compact license OK

Diversicare of Tupelo, LLC

Tupelo, MS

LVN LPN

Posted last week

  • LPN/LVN
North Mississippi Medical Center logo

North Mississippi Medical Center

Tupelo, MS

  • RN
  • ADN accepted

Diversicare of Tupelo, LLC

Tupelo, MS

Nurse RN

Posted last week

  • Sign-on bonus
  • RN
North Mississippi Medical Center logo

North Mississippi Medical Center

Tupelo, MS

  • RN
  • Per diem

Diversicare of Tupelo, LLC

Tupelo, MS

Treatment Nurse - RN

Posted last week

  • RN
  • Day shift
North Mississippi Medical Center logo

North Mississippi Medical Center

Tupelo, MS

  • RN
  • Compact license OK
  • ADN accepted

Diversicare of Tupelo, LLC

Tupelo, MS

RN Nursing Supervisor

Posted last week

  • RN

Working and living in Tupelo

· 38 open roles

Living costs

Median gross rent
$976/mo
Rent and tenant-paid utilities
Median household income
$66,257/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

2 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

6 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • NP3
  • RN28
  • LPN7
  • LVN4

One posting may accept more than one credential.

Shifts listed

  • Days16
  • Nights4
  • per-diem3
  • Rotating2

Postings may list several shifts or leave the shift unspecified.

Living in Tupelo

Anchored by the massive North Mississippi Medical Center, Tupelo stands as an energetic regional hub that punches well above its weight while maintaining the welcoming demeanor of a small Southern city.

More about life here

Healthcare professionals relocating here encounter an easy, automobile-friendly daily routine where typical commutes rarely exceed twenty minutes. Housing options span from walkable Craftsman cottages in the beloved Joyner district and urban lofts in Fairpark to quiet, leafy enclaves in Highland Circle and gated lakeside residences in Spring Lake.

Off duty, nurses enjoy a vibrant independent food scene featuring refined regional dining at Forklift, rooftop gatherings at Park Heights, and historic bites like doughburgers at Johnnie’s Drive-In. Leisure hours are spent pedaling along the scenic Natchez Trace Parkway, wandering art exhibits downtown, or attending concerts at Huntington Bank Arena.

While newcomers must adapt to sweltering summer humidity and a quieter nightlife scene compared to major metros, Tupelo offers clinical depth paired with effortless daily living and genuine community warmth.

Sources
As of Sep 16, 2026
Neighborhoods

Healthcare professionals in Tupelo gravitate toward established central pockets and growing western developments. Joyner is a perennial favorite for its walkable, sidewalk-lined streets filled with historic cottages and bungalows, placing residents within walking distance of neighborhood favorites like Forklift and CharCutie.

Downtown and the master-planned Fairpark District cater to those seeking upper-floor lofts, modern condos, and townhomes steps from dining and civic spaces. Highland Circle offers established 1920s and 1930s homes arranged around a private communal park, while Bel Air features spacious Colonial Revivals and ranch styles.

For a higher tier of suburban living, Spring Lake provides a gated enclave on the city's west side, whereas Windsor Place and Presley Heights in East Tupelo offer classic, modest homes close to Highway 78 and the Elvis Presley Birthplace. Those seeking newer apartment complexes often look toward North Tupelo along the corridor leading to Saltillo.

Sources
Housing

Tupelo's housing stock ranges from historic Craftsman bungalows to new suburban master-planned subdivisions. Rental options primarily consist of garden-style apartment communities in North Tupelo and near the mall district, alongside converted upper-floor historic lofts and new townhomes in Fairpark.

Homebuyers find established, premium inventory in Highland Circle and the gated Spring Lake community, while classic brick ranches in Bel Air and Belledeer Hills offer generous lot sizes. More accessible single-family properties are concentrated in East Tupelo and Haven Acres, where neighborhood association revitalization projects have preserved community character.

Sources
Getting around

Commutes across Tupelo are remarkably straightforward, with average drive times inside the city proper clocking in at under twenty minutes. North Mississippi Medical Center anchors the central medical district, making it easily accessible via major arteries like Highway 78, Gloster Street, and Main Street.

The city is fundamentally automobile-dependent, with minimal public transit options, but light traffic conditions and uncomplicated hospital parking make shift arrivals stress-free compared to larger metropolitan centers.

Sources
Food and dining

Tupelo features a distinct culinary footprint centered around Downtown, West Tupelo, and historic neighborhood corridors. In West Tupelo and Jackson West, Chef Cooper Miller serves elevated Southern fare at Forklift, while nearby Queen's Reward Meadery operates Mississippi's first meadery tasting room.

Downtown features scenic rooftop dining at Park Heights Restaurant, casual staples at Fairpark Grill and Café 212, and traditional barbecue at Bar-B-Que by Jim, complemented by the walkable Tupelo Cocktail Trail. Historic comfort-food landmarks include Romie's Grocery for meat-and-three lunches, Ethel Mae's for neo-soul recipes, and Johnnie's Drive-In, the city's oldest eatery where patrons still order doughburgers in the vintage Elvis booth.

Sources
Outdoors

Outdoor recreation centers around the scenic Natchez Trace Parkway, which cuts through northwest Tupelo and offers immediate access to hiking, cycling paths, and tree-lined driving routes. Within the city, the 210-acre Tupelo Buffalo Park and Zoo hosts large herds and outdoor trail walks, while neighborhood recreation thrives in Lee Acres and local park greenspaces.

For water sports and weekend camping, residents frequently head north to Pickwick Lake along the Tennessee River basin in neighboring Tishomingo County for boating, fishing, and kayaking.

Sources
Arts and culture

Tupelo's cultural identity is deeply tied to its heritage as the birthplace of Elvis Presley, drawing global visitors to the King's childhood home, museum grounds, and the annual Elvis Festival. Downtown cultural landmarks include Tupelo Hardware Company, famous for selling Elvis his first guitar, as well as the Caron Gallery celebrating regional visual artists.

Performing arts flourish through the North Mississippi Symphony Orchestra and large touring events hosted at the 10,000-seat Huntington Bank Arena. Local nightlife features intimate live music sets at venues like Ethel Mae's alongside neighborhood traditions such as the Presley Heights annual azalea garden tour.

Sources
Seasons and weather

Tupelo experiences a classic humid subtropical climate defined by long, sultry summers where temperatures frequently climb into the nineties with heavy humidity from May through September. Winters are generally short and mild, seeing only an occasional dusting of snow alongside periodic freezing snaps.

Spring arrives early with generous rainfall and lush azalea blooms, while autumn delivers a welcome break from summer heat with crisp, dry weather well suited for outdoor activities along the Natchez Trace.

Sources
For families

Tupelo offers a supportive, family-friendly environment with several residential neighborhoods organized around neighborhood associations and community parks. Districts like Joyner, Bel Air, and Belledeer Hills are noted for quiet streets, low vehicle speeds, and proximity to campuses like Parkway Elementary School.

Neighborhood revitalization efforts in Haven Acres have added modern community centers and improved public infrastructure. Families seeking suburban environments with larger yards often look toward nearby bedroom communities like Saltillo and Guntown, while staying within a brief drive of Tupelo's healthcare facilities and retail amenities.

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What locals say

Residents frequently praise Tupelo for its warm, welcoming community, clean public spaces, and genuine small-town feel combined with unexpected regional conveniences. Community members note that the west side and neighborhoods like Joyner provide quiet, friendly environments for professionals and families.

On the flip side, newcomers moving from larger cities often point out the lack of late-night extracurricular activities, limited public transportation, and a slower-paced social scene that requires personal initiative to build a network.

Sources

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