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24 nursing jobs in Portsmouth, NH

Portsmouth pairs historic waterfront walks through Prescott Park with bustling Market Square dining. Decompress kayaking Odiorne Point’s salt marshes or paddling Great Bay. Because downtown housing carries a steep premium and Piscataqua bridge lifts slow traffic, many nurses choose nearby Dover or Exeter for practical residential neighborhoods and straightforward highway commutes.

Also hiring: Portsmouth, VA (26)

Portsmouth, NH on the map· Open the live map
Edgewood Center for Rehab and Healthcare workplace
Edgewood Center for Rehab and Healthcare — a workplace named in a current Portsmouth postingView Edgewood Center for Rehab and Healthcare →

Find a nursing job in Portsmouth

Hiring here: Portsmouth Regional Hospital (7) · American Traveler (4) · Cedar Healthcare Center (2) · Edgewood Center for Rehab and Healthcare (2) · Amedisys (1) · HealthTrust Workforce Solutions (1)

Edgewood Center for Rehab and Healthcare logo

Edgewood Center for Rehab and Healthcare

Portsmouth, NH

  • Sign-on bonus
  • RN
  • 8-⁠hour nights
  • Per diem
1 / 2

RN IR Special Procedures Part Time

Portsmouth Regional Hospital logoPortsmouth Regional Hospital

Portsmouth, NH · Posted last week

  • RN
1 / 2

RN, Women’s Health

Wentworth-Douglass Hospital

Portsmouth, NH

$37–$51/hr

  • RN
  • Day shift
  • ADN accepted
1 / 2

3p-11p Registered Nurse (RN)

Edgewood Center for Rehab and Healthcare logoEdgewood Center for Rehab and Healthcare

Portsmouth, NH

$50/hr

  • Sign-on bonus
  • RN
Portsmouth Regional Hospital logo

Portsmouth Regional Hospital

Portsmouth, NH

  • RN
  • ADN accepted
  • Tuition reimbursement
Portsmouth Regional Hospital logo

Portsmouth Regional Hospital

Portsmouth, NH

  • RN
  • 12-⁠hour days
  • ADN accepted

New England Cancer Specialists

Portsmouth, NH

Oncology Infusion Room RN- Part Time

Posted last week

$67,000–$112,000/year

  • RN
  • ADN accepted
  • Tuition reimbursement

Cedar Healthcare Center

Portsmouth, NH

  • RN
  • 8-⁠hour days
  • +$5/hr differential

Portsmouth Regional Hospital

Portsmouth, NH

  • RN
  • Day shift
  • Per diem

Voyage Health

Portsmouth, NH

Travel RN PCU

$2,023–$2,129/week

  • RN
  • 12-⁠hour nights
  • Travel contract
Amedisys logo

Amedisys

Portsmouth, NH

RN Hospice Oncall Nurse

$75,000–$85,000/year

  • RN
  • Weekend shift
  • Per diem
HealthTrust Workforce Solutions logo

HealthTrust Workforce Solutions

Portsmouth, NH

  • RN
  • Day shift

Veterans Health Administration

Portsmouth, NH · Health system employer

Registered Nurse PACT CBOC (Portsmouth)

Closes Mon

$79,000–$141,000/year

  • RN
KindSpire Education logo

KindSpire Education

Portsmouth, NH · Staffing partner

  • RN
  • Day shift
  • Local contract
American Traveler logo

American Traveler

Portsmouth, NH · Staffing partner

Travel RN - PACU

$1,880/week

  • RN
  • 12-⁠hour rotating
  • 10-⁠bay PACU recovery room
TNAA Healthcare logo

TNAA Healthcare

Portsmouth, NH · Staffing partner

Med Surg RN

$1,952/week

  • RN
  • Travel contract

Cedar Healthcare Center

Portsmouth, NH

  • New grads welcomed
  • RN
  • 8-⁠hour shifts
  • Per diem
Portsmouth Regional Hospital logo

Portsmouth Regional Hospital

Portsmouth, NH

  • RN
  • Per diem
  • ADN accepted
American Traveler logo

American Traveler

Portsmouth, NH · Staffing partner

  • RN
  • Ratio 1:4
  • 12-⁠hour days
Portsmouth Regional Hospital logo

Portsmouth Regional Hospital

Portsmouth, NH

RN

$55/hr

  • RN
  • 12-⁠hour days
  • Travel contract
American Traveler logo

American Traveler

Portsmouth, NH · Staffing partner

  • RN
  • 12-⁠hour nights
  • Travel contract
Portsmouth Regional Hospital logo

Portsmouth Regional Hospital

Portsmouth, NH

  • RN
  • 12-⁠hour rotating
  • Per diem
American Traveler logo

American Traveler

Portsmouth, NH · Staffing partner

  • RN
  • 12-⁠hour days
  • Travel contract
Portsmouth Regional Hospital logo

Portsmouth Regional Hospital

Portsmouth, NH

  • RN
  • ADN accepted
  • Tuition reimbursement

Working and living in Portsmouth

· 24 open roles

Posted hourly pay

RN
$40/hr median
$39–$51/hr middle half · 8 postings

See roles with listed pay

Living costs

Median gross rent
$1,869/mo
Rent and tenant-paid utilities
Median household income
$106,219/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

2 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

0 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • RN24

One posting may accept more than one credential.

Shifts listed

  • Days9
  • Nights3
  • per-diem3
  • Rotating2
  • weekend1

Postings may list several shifts or leave the shift unspecified.

Living in Portsmouth

Portsmouth pairs historic maritime character with a lively, urbane energy that distinguishes it from typical small New England seaports.

More about life here

For relocating healthcare professionals, the city offers an exceptional quality of life defined by waterfront walks through Prescott Park, living history at Strawbery Banke, and an extraordinary culinary scene anchored by Market Square restaurants such as Row 34 and River House. Natural escapes abound nearby, from coastal kayaking at Odiorne Point State Park in Rye to paddleboarding along Great Bay in Greenland.

However, living directly in Portsmouth involves real tradeoffs: housing inventory is notoriously tight and competitive, downtown parking becomes challenging during peak summer tourist waves, and river bridge lifts can unpredictably slow commutes across the Piscataqua. Consequently, many nurses choose to live in vibrant neighboring hubs like Dover or Exeter, enjoying straightforward highway access to Portsmouth while taking full advantage of the Seacoast's cultural depth and coastal charm.

Sources
As of Sep 16, 2026
Neighborhoods

Downtown Portsmouth offers walkable, historic streets near the waterfront with compact apartments and condos, appealing to professionals seeking immediate access to dining and retail. Nearby suburban and coastal enclaves include Greenland, known for quiet residential living near Great Bay, upscale Rye with its coastal conservation focus, and the historic island enclave of New Castle.

Because housing within Portsmouth proper carries a notable premium, many commuters and healthcare workers look inland to Dover, Exeter, Somersworth, Stratham, or Epping, where established residential neighborhoods and easier highway connections offer practical alternatives.

Sources
Housing

Housing in Portsmouth ranges from historic colonial properties and attached townhomes to modern downtown condominiums and traditional single-family suburban homes. Demand is persistently high, creating a competitive market where finding rental vacancies in town requires quick decision-making.

As a result, healthcare workers and young professionals frequently choose to rent or buy in neighboring Dover, Somersworth, or Exeter, where single-family homes and garden-style apartment communities offer greater availability.

Sources
Getting around

Commuting into Portsmouth typically relies on regional road arteries connecting nearby towns like Dover, Exeter, and Stratham, with highway access playing a central role for daily drivers. A key logistical quirk of local travel involves the drawbridges connecting Portsmouth across the Piscataqua River, which raise and lower on schedules driven by marine vessel traffic and can trigger sudden vehicle bottlenecks during shift changes.

In addition, summer tourist influxes bring heavier congestion and tighter parking availability downtown.

Sources
Food and dining

Portsmouth boasts a renowned food culture celebrated for having more restaurant seats than residents, driven by sea-to-table cuisine, independent cafes, and craft breweries. Key culinary draws include waterfront favorites like River House, seafood dining at Row 34, and upscale eateries such as Botanica.

The focal point of dining life surrounds Market Square, where independent bakeries and pubs line the brick sidewalks, though off-shift options taper outside core commercial districts.

Sources
Outdoors

The Seacoast region provides direct outdoor recreation spanning ocean shores, tidal bays, and inland trails. In town, waterfront Prescott Park showcases formal flower gardens and fountains along the river, while neighboring Rye features Odiorne Point State Park for coastal hiking, tidal pool exploration, and kayaking through salt marshes.

Greenland provides access to Great Bay for paddling and nature walks, and regional day trips easily reach Lake Winnipesaukee and the White Mountains for skiing and alpine hiking.

Sources
Arts and culture

Portsmouth balances deep maritime heritage with active contemporary arts programming. Historic Strawbery Banke operates as a ten-acre living history museum depicting multi-century architecture, while the Seacoast Repertory Theatre delivers year-round stage productions.

Annual community gatherings center around Market Square Day and the Prescott Park Chowder Festival, complemented by live outdoor summer concerts and a walkable downtown retail district featuring local spots like Gus & Ruby Letterpress, Nahcotta, and Treehouse Toys.

Sources
Seasons and weather

Summers on the Seacoast are vibrant and pleasant, marked by active harbor traffic, outdoor dining, and regional beachgoers, though accompanied by noticeable tourism crowds. Autumn brings crisp coastal air and scenic fall foliage throughout the surrounding river valleys and nearby White Mountain corridors.

Winters bring cold temperatures, occasional coastal storms, and snow that demands winter driving readiness, though proximity to regional ski areas appeals to winter sports enthusiasts.

Sources
For families

Portsmouth and surrounding Seacoast communities are highly regarded for family life, supported by well-rated public school systems, safe residential pockets, and strong civic engagement. Towns like Greenland and Rye offer quiet neighborhoods with expansive yards, local parks, and family events such as Greenland Old Home Days.

Families also benefit from family-friendly downtown attractions, including child-oriented shopping in Market Square and extensive outdoor educational programming at the Seacoast Science Center in Odiorne Point State Park.

Sources
What locals say

Residents consistently praise Portsmouth for its vibrant coastal setting, strong school options, safe neighborhoods, and an outsized cultural and dining scene that feels far larger than the city's modest footprint. The primary drawbacks cited by locals are steep housing expenses and tight real estate availability, which frequently push working professionals to consider surrounding communities like Dover or Somersworth.

Sources

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