54 nursing jobs in Appleton, WI
Anchored along the Fox River, Appleton connects top Fox Valley healthcare hubs like ThedaCare Regional and Ascension St. Elizabeth with a walkable, historic downtown on College Avenue. Commutes are seamless and living costs run about 8% below the national average, letting nurses build a high-impact clinical career backed by genuine Wisconsin ease and community warmth.
Find a nursing job in Appleton
Hiring here: Ascension (28) · ThedaCare (13) · Appleton Comprehensive Treatment Center (2) · Anovia Health (1) · Eden Senior Care (1) · Foremost Farms (1)
- RN
- Monday-Friday (0530-1800 depending on cases)
- NP

ThedaCare
10 open roles · day & rotating shifts
ThedaCare
10 open roles · day & rotating shifts
RN Clinical Nurse (Ambulatory) - Family Practice
Appleton, WI
- RN
- Day shift
- ADN accepted
Operating Room RN - Days & No Weekends
Appleton, WI
- RN
- Start times could vary between 6-8:30a
- ADN accepted
CMA - LPN - Trauma Foot and Ankle
Appleton, WI
- LPN
- Day shift
CMA - LPN - Family Practice
Appleton, WI
- LPN
- Day shift
Licensed Practical Nurse - Cardiac Specials
Appleton, WI
- LPN
- Day shift
Emergency Department RN - Day Shift
Appleton, WI
- RN
- 12-hour days
Registered Nurse (SANE)
Appleton, WI
- RN
- Rotating shift
- Per diem
Sexual Assault RN Examiner - Call Only
Appleton, WI
- RN
- Per diem
- ADN accepted
RN Clinical Nurse (Ambulatory) - Remote - Days
Appleton, WI
- RN
- 8-hour days
- ADN accepted
RN Clinical Nurse (Urgent Care)
Appleton, WI · Posted 5 days ago
- RN
IRIS Self-Directed Personal Care (RN) (Winnebago County, WI, Calumet County, WI, & Outagamie County, WI)
Posted last week
$26–$51/hr
- RN
- RN
- Day shift
- Tuition reimbursement
Appleton Comprehensive Treatment Center
Appleton, WI
RN or LPN (Part Time)
Posted 5 days ago
- RN/LPN
- Day shift
Registered Nurse (RN)
$35–$42/hr
- Sign-on bonus
- RN
- Day shift
- Tuition reimbursement
- New grads welcomed
- RN
- MWF: 0400-2000 TTS: 0400-1700
Travel Med-Surg Registered Nurse (RN) - Appleton, WI
$2,178–$2,304/week
- RN
- Travel contract
Appleton Comprehensive Treatment Center
Appleton, WI
- LPN
- 5:00 AM - 1:00 PM
- Tuition reimbursement
Ascension
21 open roles · night & day shifts
Ascension
21 open roles · night & day shifts
- RN
- RN
- 12-hour nights
- Regional Float Pool ICU
- RN
- 12-hour nights
- Med/Surg
- RN
- Full-time nights
- Compact license OK
- RN
- 12-hour nights
- Med/Surg
- RN
- 12-hour nights
- Stepdown
- RN
- 12-hour nights
- Stepdown
- RN
- 12-hour nights
- Mother Baby
- LPN
- Part-time days
- Adult Psychiatry
- New grads welcomed
- LPN
- Part-time days
- Adult Psychiatry
- RN
- Day shift
- Compact license OK
- RN
- Days | PRN
- Per diem
- RN
- Day shift
- Per diem
- RN
- 12-hour days
- Compact license OK
- RN
- Full-time days
- Compact license OK
- RN
- 12-hour days
- Adolescent Psychiatry
- RN
- Full-time days | Monday-Friday
- Behavioral Health Unit
- RN
- Day shift
- Compact license OK
Registered Nurse Anticoagulation Clinic
Appleton, WI · Posted 5 days ago
- RN
- Day shift
Registered Nurse Behavioral Health
Appleton, WI · Posted last week
- RN
- 12-hour nights
Registered Nurse Behavioral Health
Appleton, WI · Posted last week
- RN
- 12-hour nights
Working and living in Appleton
· 54 open roles
Living costs
- Median gross rent
- $1,030/mo
- Rent and tenant-paid utilities
- Median household income
- $80,483/yr
- All local households, not nurse pay
New to our board this week
6 current postings first appeared here in the past seven days.
Credentials accepted
- NP1
- RN46
- LPN8
One posting may accept more than one credential.
Shifts listed
- Days28
- Nights15
- Rotating2
Postings may list several shifts or leave the shift unspecified.
Living in Appleton
Positioned along the Fox River, Appleton stands out as the cultural and commercial anchor of Wisconsin's Fox Cities, pairing small-town Midwestern warmth with surprising metropolitan amenities.
More about life hereShow less
For relocating healthcare professionals, the city offers seamless access to three major regional hospital systems via Highway 41, keeping typical commutes under twenty minutes with virtually no metropolitan gridlock. Daily life gravitates around a walkable downtown corridor centered on College Avenue, where Lawrence University's leafy campus merges with indie boutiques, riverfront dining at places like Pullman's, and premier venues like the Fox Cities Performing Arts Center.
Families and individuals settle into historic residences near City Park, mid-century homes on the north side, or neighboring communities like Neenah and Grand Chute, benefiting from top-rated public and charter schools. While snowy Midwestern winters demand serious seasonal adaptation and transit requires a personal vehicle, Appleton rewards newcomers with abundant riverfront parks, summer music events like Mile of Music, and a remarkably tight-knit community feel.
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Neighborhoods
Historic neighborhoods surround City Park and Lawrence University, offering classic architectural character within walking distance of downtown cultural venues. The north side features mid-century modern ranches alongside newer residential subdivisions, while nearby communities like Neenah, Grand Chute, Greenville, and Freedom attract residents seeking quiet suburban or semi-rural enclaves across the Fox Valley.
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Housing
Appleton offers a balanced mix of architectural housing types, ranging from historic character properties near City Park and Lawrence University to mid-century modern single-story ranches and newer single-family subdivisions on the north side. Prospective residents can also explore diverse rental and purchase options in adjacent Fox Valley towns, balancing quieter residential layouts with proximity to central city amenities.
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Getting around
Commutes throughout Appleton and the greater Fox Cities are typically swift and straightforward, with average drive times ranging between 17 and 20 minutes and minimal traffic bottlenecks. Highway 41 serves as the primary regional corridor connecting Appleton to neighboring health systems and communities like Neenah, Oshkosh, and Green Bay, though limited bus coverage means daily transit relies heavily on personal vehicles.
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Food and dining
Downtown Appleton along College Avenue serves as the epicenter of dining, featuring elevated options like Rye, popular daytime gathering spot SAP Brunch, and confections from Wilmar Chocolates. Scenic riverfront dining is anchored by establishments like Fratello's, Pullman's, and Fox River Brewing Company, while broader local favorites include traditional supper club fish fries at Wishing Well, authentic Mexican cuisine at El Sabor, and the iconic year-round holiday atmosphere at Cleo's.
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Outdoors
Outdoor recreation centers on the Fox River and nearby Lake Winnebago, providing extensive networks of walking and biking trails alongside riverfront parks. Residents frequently spend time in Appleton Memorial Park for its open gardens, walking paths, and recreational facilities, make day trips east to High Cliff State Park for lake bluffs and hiking, or explore peaceful boardwalk trails at Heckrodt Wetland Reserve in nearby Menasha.
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Arts and culture
As the cultural hub of the Fox Cities, Appleton hosts touring Broadway productions and regional concerts at the Fox Cities Performing Arts Center alongside creative exhibits at the Trout Museum of Art. Local heritage is celebrated through sites like the History Museum at the Castle, the Paper Discovery Center, and the Hearthstone Historic House Museum, while civic energy culminates at downtown gatherings like the Mile of Music festival and summer concerts in Houdini Plaza.
Seasons and weather
Winters bring significant snowfall and sustained freezing temperatures, making warm gear essential while the community stays engaged with snowshoeing trails and indoor arts venues. Warm weather arrives with lush greenery along the Fox River Valley, setting off a vibrant summer calendar filled with open-air markets, outdoor concert series, and lakeside recreation before transitioning into crisp, colorful autumns.
For families
Appleton is well-regarded for families, offering safe residential neighborhoods anchored by the Appleton Area School District, which includes well-rated elementary schools like Houdini and Janet Berry alongside magnet options like Tesla Engineering Charter School and Appleton Public Montessori. Secondary education is served by Appleton North, East, and West High Schools alongside established private networks like Xavier Catholic, supported outside school hours by community destinations like the Building For Kids Children's Museum.
What locals say
Residents consistently praise Appleton for its exceptionally friendly Midwestern community, clean industrial and municipal areas, and vibrant downtown that feels far livelier than typical small cities. Common drawbacks mentioned by locals include long, cold winters, minimal public transit options, and emerging local discussions around neighborhood growth and rising living expenses.

