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200 nursing jobs in Des Moines, IA

Des Moines pairs low-friction Midwestern living with an enviable paycheck stretch—expenses sit about 8% below the national average. Trade brutal hospital commutes for easy neighborhood drives, decompress post-shift along the Principal Riverwalk, and spend off-days exploring the Historic East Village. It’s an unpretentious, high-yield landing spot for nurses ready to keep what they earn.

Des Moines, IA on the map· Open the live map
Pediatric and Adult Allergy, PC workplace
Pediatric and Adult Allergy, PC — a workplace named in a current Des Moines postingView Pediatric and Adult Allergy, PC →

Find a nursing job in Des Moines

Hiring here: Veterans Health Administration (47) · UnityPoint Health (37) · MercyOne (22) · FirstChoice (13) · Select Specialty Hospital - Des Moines (8) · Broadlawns Medical Center (6)

Pediatric and Adult Allergy, PC

Des Moines, IA

  • RN
  • Day shift
1 / 2

Registered Nurse (RN) - Weekend Package

Accura HealthCare of South Des Moines logoAccura HealthCare of South Des Moines

Des Moines, IA

$36–$44/hr

  • RN
  • Weekend shift

Registered Nurse Night Shift

Azria Health logoAzria Health

Des Moines, IA

  • Sign-on bonus
  • RN
  • Night shift
1 / 2
  • RN
  • 12-⁠hour days
1 / 2

Registered Nurse

Planned Parenthood North Central States logoPlanned Parenthood North Central States

Des Moines, IA

$30–$39/hr

  • RN
1 / 2

Regional Director of Nursing, DON

Legacy Healthcare logoLegacy Healthcare

Des Moines, IA

  • RN
  • Per diem
  • ADN accepted
1 / 4

RN - Cardiac Tele Heart Failure

MercyOne logoMercyOne

Des Moines, IA · Posted last week

  • Sign-on bonus
  • RN
  • 12 Hour Night Shift
  • 7S
Accura HealthCare of South Des Moines logo

Accura HealthCare of South Des Moines

Des Moines, IA

  • RN
  • Night shift
  • Compact license OK
Planned Parenthood North Central States logo

Planned Parenthood North Central States

Des Moines, IA

  • RN
MercyOne logo

MercyOne

Des Moines, IA

  • RN
  • 12-⁠hour nights
  • Progressive Care Unit
MercyOne logo

MercyOne

Des Moines, IA

  • RN
  • Night shift
  • OB Emergency Department – Antepartum Unit

Iowa Jewish Senior Life Center

Des Moines, IA

Registered Nurse

From $39/hr

  • RN
  • 12-⁠hour days
Iowa Total Care logo

Iowa Total Care

Des Moines, IA

Maternity RN Care Manager

$56,000–$101,000/year

  • RN
  • 8-⁠hour days
  • Compact license OK

Select Specialty Hospital - Des Moines

Des Moines, IA

  • RN
  • 12-⁠hour shifts
  • Per diem

Vibra Travels LLC

Des Moines, IA

  • RN
  • Travel contract

Trinity Center

Des Moines, IA

  • RN

FC Compassus, LLC

Des Moines, IA

  • NP
  • Night shift
  • Per diem

Ramsey Village Continuing Care

Des Moines, IA

RN Wound Nurse

Posted 2 weeks ago

  • RN
Accura HealthCare of South Des Moines logo

Accura HealthCare of South Des Moines

Des Moines, IA

  • RN
  • Rotating shift

UnityPoint Health

Des Moines, IA

  • Sign-on bonus
  • RN
  • Evening shift
  • New grads welcomed
Angels Care Home Health logo

Angels Care Home Health

Des Moines, IA

  • RN
  • Rotating shift
  • ADN accepted

Genie Healthcare

Des Moines, IA

Med Surg / Telemetry (RN)

Up to $2,280/week

  • RN
  • Ratio 1:3–1:7
  • Night shift
Accura HealthCare logo

Accura HealthCare

Des Moines, IA

  • LPN
  • 12-⁠hour days

MercyOne

Des Moines, IA

  • RN
  • Evening shift
  • Per diem
FirstChoice logo

FirstChoice

Des Moines, IA

  • RN
  • 12 Hour Day Shift
  • Travel contract
Cassia logo

Cassia

Des Moines, IA

Registered Nurse RN 5000 Bonus

Posted 6 days ago

From $38/hr

  • Sign-on bonus
  • RN
  • New grads welcomed
Select Specialty Hospital logo

Select Specialty Hospital

Des Moines, IA

  • Sign-on bonus
  • RN
  • Full-Time Days (12-⁠Hour Shifts)
  • Tuition reimbursement

Trinity Health

Des Moines, IA

  • Sign-on bonus
  • RN
  • 12-⁠hour nights
  • Compact license OK
Affinity Hospice Management LLC logo

Affinity Hospice Management LLC

Des Moines, IA

  • RN
  • Night shift
  • CEU allowance
NaphCare, Inc. logo

NaphCare, Inc.

Des Moines, IA

  • New grads welcomed
  • RN
  • Tuition reimbursement
Daisy Medical Staffing Inc logo

Daisy Medical Staffing Inc

Des Moines, IA · Staffing partner

  • RN
  • 12-⁠hour nights
  • Agency contract
Voyage Health logo

Voyage Health

Des Moines, IA · Staffing partner

Travel RN Emergency Room

$2,021–$2,128/week

  • RN
  • 12-⁠hour nights
  • Travel contract

Select Specialty Hospital - Des Moines

Des Moines, IA

Registered Nurse (RN) - Per Diem

Posted last week

$47/hr

  • RN
  • 12-⁠hour shifts
  • Per diem

FC Compassus, LLC

Des Moines, IA

  • RN
  • Per diem

UnityPoint Health

Des Moines, IA

  • Sign-on bonus
  • CNA
  • Rotating shift
  • +$2.65/hr differential
Accura HealthCare logo

Accura HealthCare

Des Moines, IA

  • LPN
  • Day Shift 6:00AM to 6:00PM Friday, Saturday, Sunday
FirstChoice logo

FirstChoice

Des Moines, IA

  • RN
  • 12-⁠hour nights
  • Travel contract
Cassia logo

Cassia

Des Moines, IA

  • Sign-on bonus
  • RN
  • Day shift
  • Compact license OK
Affinity Hospice Management LLC logo

Affinity Hospice Management LLC

Des Moines, IA

  • RN
  • Per diem
  • CEU allowance

Select Specialty Hospital - Des Moines

Des Moines, IA

Clinical Liaison

Posted last week

  • Sign-on bonus
  • RN
  • Day shift
Accura HealthCare logo

Accura HealthCare

Des Moines, IA

  • LPN
  • 12-⁠hour nights
  • Tuition reimbursement
FirstChoice logo

FirstChoice

Des Moines, IA

  • RN
  • 12-⁠hour evenings
  • Travel contract
Cassia logo

Cassia

Des Moines, IA

  • Sign-on bonus
  • CNA
  • Day shift
  • Compact license OK

Select Specialty Hospital - Des Moines

5 open roles · Night · Permanent

Registered Nurse (RN) - Full-Time Night Shift

Des Moines, IA · Posted last week

$37–$50

  • Sign-on bonus
  • RN
  • 12-⁠hour nights
  • New grads welcomed

Registered Nurse (RN) - Full-Time Day Shift

Des Moines, IA · Posted last week

$37–$50

  • Sign-on bonus
  • RN
  • 12-⁠hour nights
  • New grads welcomed

Registered Nurse (RN) - Full-Time New Graduate

Des Moines, IA · Posted last week

  • Sign-on bonus
  • RN
  • Night shift

House Supervisor (RN) - Full-time Night Shift

Des Moines, IA · Posted last week

  • Sign-on bonus
  • RN
  • Night shift

Registered Nurse (RN) - Full-Time New Graduate

Des Moines, IA · Posted last week

  • Sign-on bonus
  • RN

Working and living in Des Moines

· 200 open roles

Posted hourly pay

RN
$38/hr median
$36–$39/hr middle half · 9 postings

See roles with listed pay

Living costs

Metro price level
91.7 (100 = national)
BEA 2024
Median gross rent
$1,090/mo
Rent and tenant-paid utilities
Median household income
$65,932/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

46 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

18 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • NP3
  • APRN3
  • RN178
  • LPN12
  • LVN1
  • CNA2

One posting may accept more than one credential.

Shifts listed

  • Days65
  • Nights61
  • Rotating15
  • per-diem9
  • Evenings4
  • weekend3

Postings may list several shifts or leave the shift unspecified.

Living in Des Moines

Des Moines is a compact Midwest capital where a nurse's paycheck stretches: city median homes sit near $212,000, Beaverdale around $275,000, West Des Moines and Ankeny around $345,000, with downtown typically 15–25 minutes away.

More about life here

What is distinct is insurance-and-finance jobs plus a free sculpture park and Art Center, a nationally ranked Downtown Farmers' Market, and 800-plus miles of trails around Gray's Lake. Young professionals often start in Beaverdale or East Village; families pick Ankeny's Prairie Trail, West Des Moines near Jordan Creek, Waukee, Johnston, or quieter Grimes.

You will need a car—DART's Transit Score is 30—and I-235 west is a daily snarl, while Ankeny via I-35 is the commute locals praise. Eat on Court Avenue, in Historic Valley Junction, and along Ingersoll and Grand (Centro, Harbinger, Smokey D's).

Tradeoffs are real: long icy winters, humidity, tornadoes, potholes, no pro sports, and quieter nightlife—offset by A+ suburban schools, short drives, and room to buy.

Sources
As of Sep 11, 2026
Neighborhoods

Young professionals often land in Beaverdale for bungalow charm and walkability (about $275,000 median) or in East Village for downtown energy. West Des Moines near Jordan Creek Town Center is the established family-and-amenities suburb at about $345,000 with a 15–20 minute downtown drive; Ankeny’s Prairie Trail mixed-use district and new subdivisions match that price with a 15–25 minute I-35 commute.

Waukee skews newer and larger near $390,000; Clive sits between West Des Moines and Urbandale with I-35/I-80 access at a higher median. Grimes, Bondurant, and Nevada come up for more house for the money; locals warn western suburbs clog I-235 every weekday while Ankeny is the easier downtown run.

Sources
Housing

Inside Des Moines, U.S. News lists a median home value of $211,651 and median rent of $938; other 2024 snapshots put median sale near $210,000 and one-bedroom rent around $1,120, with apartment rents roughly $949–$1,123. Central Iowa MLS medians through July 2026: Beaverdale $275,000, West Des Moines and Ankeny $345,000, Waukee $390,000, Clive $500,000—versus a national average home value of $359,870. New construction in Ankeny and Waukee often starts in the $300,000s; Grimes is frequently cheaper than neighboring Waukee or Johnston. Housing costs sit well below similarly sized metros.

Sources
Getting around

U.S. News puts the typical Des Moines commute at about 17 minutes. Suburb-to-downtown drives are generally 12–18 minutes from Clive, 15–20 from West Des Moines, 15–25 from Ankeny, and 20–30 from Waukee.

Ankeny along I-35 is the commute locals call great; western suburbs make I-235 westbound a daily mess. DART buses exist but the Transit Score is 30, so suburban workers plan on a car rather than transit.

Sources
Food and dining

Named restaurant districts include East Village, Historic Valley Junction, the Avenues of Ingersoll and Grand, downtown Court Avenue, Uptown Ankeny, and The District at Prairie Trail. Community picks include Court Avenue Brewery, Smokey D's, Jethro's, and Buzzard Billy's.

Chef-driven names are George Formaro's Centro and Zombie Burger and Joe Tripp's Harbinger and Alba; Crème Cupcake + Dessert and Oak Park add destination dining. Jordan Creek Town Center covers suburban shopping-and-dinner runs in West Des Moines.

Sources
Outdoors

Gray's Lake Park is the in-town loop; the metro claims more than 75 parks and over 800 miles of trails, including the High Trestle Trail, Raccoon River Valley Trail, Clive's Greenbelt Trail, and paths through Ankeny's Prairie Trail. North of town, Johnston uses Beaver Creek Natural Resource Area and Saylorville Lake; Waukee's Triumph Park is a family sports-and-green-space draw.

Blank Park Zoo and the Greater Des Moines Botanical Garden on the riverfront fill weekend hours.

Sources
Arts and culture

Pappajohn Sculpture Park is the free downtown landmark against the skyline; the Des Moines Art Center is typically free and strong on modern and contemporary work. Add the nationally ranked Downtown Farmers' Market, the Des Moines Arts Festival, Science Center of Iowa, the gold-domed Iowa State Capitol, and a free State Historical Museum.

Performing arts include ballet, opera, symphony, theater, and the Des Moines Community Playhouse; East Village is the boutique-and-evening neighborhood. There are no pro sports franchises, and some locals say the weekend concert calendar is thin.

Sources
Seasons and weather

Winter is the season newcomers underestimate: heavy snow, freezing temperatures lasting several months, icy roads, and constant snow removal. Humidity, strong allergy seasons, and tornado risk are the warm-weather counterparts; Canadian wildfire smoke has also affected Iowa air quality.

The landscape is very flat, so there is little topographic relief from wind or weather. Trail and lake life at Gray's Lake and Saylorville is how residents use the non-winter months.

Sources
For families

West Des Moines, Ankeny, and Waukee community school districts are all described as A+; Johnston regularly appears on Iowa top-10 lists, and Dallas Center-Grimes is well regarded. Ankeny CSD serves more than 13,000 students; family infrastructure includes Prairie Ridge Sports Complex, Triumph Park, trail systems, and active neighborhood associations.

Nevada, Ankeny, and Bondurant are the names that come up for combining still-good schools with more affordable housing. Most of these suburbs sit 15–30 minutes from downtown, the family-commute range sources treat as normal.

Sources
What locals say

Residents praise affordability, short commutes, plentiful low- or no-cost parks and events, and a friendliness some jokingly call too nice. West Des Moines commenters add good amenities and little political extremism.

Recurring cons are harsh multi-month winters, potholes and constant road construction, car dependence, humidity, tornadoes, allergies, a slower nightlife and thin weekend concert calendar, and no pro sports teams. Versus bigger cities, people say it is cleaner, very flat, and slower-paced—either the point or the drawback.

Sources

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