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169 nursing jobs in Harrisburg, PA

Anchored along the Susquehanna River with UPMC overlooking the water, Harrisburg pairs capital-city healthcare careers with a cost of living about 1% below the national average. Trade brutal commutes for Midtown brick rowhomes, post-shift runs through Riverfront Park, and Saturday morning snacks at the historic Broad Street Market.

Harrisburg, PA on the map· Open the live map
Helen M. Simpson Rehabilitation Hospital workplace
Helen M. Simpson Rehabilitation Hospital — a workplace named in a current Harrisburg postingView Helen M. Simpson Rehabilitation Hospital →

Find a nursing job in Harrisburg

Hiring here: UPMC (116) · Helen M. Simpson Rehabilitation Hospital (12) · Select Specialty Hospital - Harrisburg (4) · CO-17 Patient First Pennsylvania Medical Group, P.L.L.C. (2) · CVS Health (2) · Compassus (2)

Helen M. Simpson Rehabilitation Hospital logo

Helen M. Simpson Rehabilitation Hospital

Harrisburg, PA

Registered Nurse (RN) - Per Diem

Posted 6 days ago

$50/hr

  • Sign-on bonus
  • RN
  • Per diem
1 / 2

Charge Registered Nurse (RN)

Panacea Health Corp logoPanacea Health Corp

Harrisburg, PA

  • RN
  • 8-⁠hour 8 hour
Helen M. Simpson Rehabilitation Hospital workplace

Helen M. Simpson Rehabilitation Hospital

11 open roles · Hospital

Registered Nurse (RN) - Per Diem - Tier 2

Harrisburg, PA · Posted last week

$60/hr

  • RN
  • 12-⁠hour shifts
  • Per diem

Per-Diem Clinical Liaison (RN, PT, OT, SLP)

Harrisburg, PA · Posted last week

$45/hr

  • RN
  • Per diem

Registered Nurse (RN) - Full-time -Day

Harrisburg, PA · Posted last week

$40–$54/hr

  • Sign-on bonus
  • RN

Student Nurse Tech (SNT) - PRN

Harrisburg, PA · Posted last week

$20/hr

  • RN
  • Per diem

Registered Nurse (RN) - Per Diem

Harrisburg, PA · Posted last week

$50/hr

  • Sign-on bonus
  • RN
  • Per diem

Registered Nurse (RN) - Per Diem - Tier 2

Harrisburg, PA · Posted last week

$60/hr

  • RN
  • 12-⁠hour shifts
  • Per diem

Registered Nurse (RN) - Full-time Nights

Harrisburg, PA · Posted last week

$40–$54/hr

  • Sign-on bonus
  • RN
  • Night shift

Registered Nurse (RN) - Full-time -Day

Harrisburg, PA · Posted last week

$40–$54/hr

  • Sign-on bonus
  • RN
  • Night shift

Registered Nurse (RN) - Full-time - Day

Harrisburg, PA

$40–$54/hr

  • Sign-on bonus
  • RN
  • Day shift

Nurse Manager

Harrisburg, PA · Posted last week

  • RN

RN Quality Coordinator -Full Time

Harrisburg, PA · Posted last week

  • RN
  • Day shift
Capital Blue Cross logo

Capital Blue Cross

Harrisburg, PA

  • LPN
  • Tuition reimbursement
RN Infusion logo

RN Infusion

Harrisburg, PA

  • RN

Spring Creek Rehabilitation and Nursing Center

Harrisburg, PA

  • Sign-on bonus
  • LPN
  • Shifts Available: 7a-7p, 7p-7a
  • Transitional Care Rehab Unit
Hospice of Central PA logo

Hospice of Central PA

Harrisburg, PA

  • RN
  • Per diem
  • 5–6 week orientation

Capital Surgery and Laser Center

Harrisburg, PA

LPN (Licensed Practical Nurse)

Posted 6 days ago

From $28/hr

  • LPN

Select Specialty Hospital - Harrisburg

Harrisburg, PA

Senior Clinical Liaison

Posted today

$90,000–$105,000/year

  • Sign-on bonus
  • RN
  • Day shift

Shadai Home Health Services

Harrisburg, PA

LPN (Licensed Practical Nurse)

Posted 4 days ago

$28–$35/hr

  • LPN
  • Per diem
Aspire Family Medicine logo

Aspire Family Medicine

Harrisburg, PA

  • NP
  • 10-⁠hour shifts

CO-17 Patient First Pennsylvania Medical Group, P.L.L.C.

Harrisburg, PA

Nurse-RN

Posted 5 days ago

  • RN
Viva Senior Living logo

Viva Senior Living

Harrisburg, PA

  • RN/LPN
Helping Hand Nurse, LLC logo

Helping Hand Nurse, LLC

Harrisburg, PA

RN Home Health Care Nurse

Posted yesterday

$40–$50/hr

  • RN

Serenity Hospice Care Pennsylvania

Harrisburg, PA

  • LPN
  • Day shift

Emerald Nursing and Rehabilitation

Harrisburg, PA

  • LPN
  • Evening shift
  • Per diem

Beacon Specialized Living

Harrisburg, PA

  • LPN

UPMC

Harrisburg, PA

  • RN
  • 12-⁠hour rotating

Epic Healthcare

Harrisburg, PA

  • RN
  • Day shift
CVS Health logo

CVS Health

Harrisburg, PA

Sr. Manager - Business Compliance

$68,000–$199,000/year

  • RN
  • ADN accepted
Penn Staffing Services LLC logo

Penn Staffing Services LLC

Harrisburg, PA · Staffing partner

  • New grads welcomed · reported
  • LPN
  • Weekend shift
  • Agency contract
Penn Staffing Solutions logo

Penn Staffing Solutions

Harrisburg, PA · Staffing partner

  • New grads welcomed · reported
  • RN
  • Agency contract
  • +$2/hr differential

Spring Creek Rehabilitation and Nursing Center

Harrisburg, PA

  • New grads welcomed · reported
  • RN
  • Weekend shift
  • +$4/hr differential
Hospice of Central PA logo

Hospice of Central PA

Harrisburg, PA

  • RN
  • 12-⁠hour days
  • Tuition reimbursement

Select Specialty Hospital - Harrisburg

Harrisburg, PA

Registered Nurse (RN) - Per Diem

Posted last week

$50/hr

  • Sign-on bonus
  • RN
  • Per diem

CO-17 Patient First Pennsylvania Medical Group, P.L.L.C.

Harrisburg, PA

Nurse-RN

Posted last week

  • RN
Helping Hand Nurse, LLC logo

Helping Hand Nurse, LLC

Harrisburg, PA

RN Home Health Care Nurse (Harrisburg)

Posted last week

$40–$50/hr

  • RN
  • Night shift
UPMC logo

UPMC

Harrisburg, PA · Health system employer

  • New grads welcomed
  • CRNA

Spring Creek Rehabilitation and Nursing Center

Harrisburg, PA

  • RN
  • Day shift

Select Specialty Hospital - Harrisburg

Harrisburg, PA

Acute Care Registered Nurse (RN)

Posted last week

$40–$54/hr

  • Sign-on bonus
  • RN
  • 12-⁠hour rotating
UPMC logo

UPMC

Harrisburg, PA · Health system employer

CRNA, UPMC Harrisburg

Posted last week

$230k–$346k

t us provide you with a life-changing career, including student loan forgiveness, a salary range of $230k - $346k, an employer-funded retirement plan and up to $125k sign-on.

  • New grads welcomed
  • CRNA

Select Specialty Hospital - Harrisburg

Harrisburg, PA

  • Sign-on bonus
  • RN
  • Day shift

UPMC

5 open roles · rotating & per diem shifts · Permanent

Chief CRNA, UPMC Harrisburg

Harrisburg, PA · Posted last week

  • CRNA

CRNA, UPMC Harrisburg

Harrisburg, PA · Posted last week

$230k–$346k

t us provide you with a life-changing career, including student loan forgiveness, a salary range of $230k - $346k, an employer-funded retirement plan and up to $100k sign-on.

  • Sign-on bonus
  • CRNA
  • New grads welcomed

Certified Nurse Midwife - UPMC Women's First

Harrisburg, PA · Posted last week

  • CNM
  • Rotating shift

CRNA Casual, UPMC Harrisburg

Harrisburg, PA · Posted last week

  • CRNA

CRNA Part-Time, UPMC Harrisburg

Harrisburg, PA · Posted last week

  • New grads welcomed
  • CRNA

Working and living in Harrisburg

· 169 open roles

Posted hourly pay

RN
$42/hr median
$40–$55/hr middle half · 5 postings

See roles with listed pay

Living costs

Metro price level
98.7 (100 = national)
BEA 2024
Median gross rent
$1,062/mo
Rent and tenant-paid utilities
Median household income
$48,099/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

13 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

20 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • DNP1
  • CRNA8
  • CNM1
  • NP3
  • RN75
  • LPN15
  • LVN1

One posting may accept more than one credential.

Shifts listed

  • Nights45
  • per-diem32
  • Days29
  • Rotating17
  • weekend11
  • Evenings4

Postings may list several shifts or leave the shift unspecified.

Living in Harrisburg

Harrisburg offers healthcare professionals the distinct pace of a riverfront state capital paired with small-city accessibility and central mid-Atlantic connectivity.

More about life here

Life here revolves around the Susquehanna River, which shapes both recreation and the daily commute. Clinicians heading to major employers like Penn State Health Milton S. Hershey Medical Center must weigh the East Shore versus West Shore divide: living in vibrant urban pockets like Midtown provides walkable access to Broad Street Market, Sprocket murals, and Riverfront Park, while suburban West Shore havens like Camp Hill and Mechanicsburg offer newer construction and sought-after school districts.

Commuters must account for bridge congestion during peak shift changes along Interstate 81, Interstate 83, and Route 322. When off duty, nurses can bike the 20-mile Capital Area Greenbelt, catch a Harrisburg Senators game on City Island, or take advantage of quick weekend escapes to Baltimore, Philadelphia, or Washington, D.C. While grocery options often require a car and urban blocks require street-level discernment, Harrisburg delivers a grounded, community-focused lifestyle with abundant green space.

Sources
As of Sep 16, 2026
Neighborhoods

Harrisburg is geographically split by the Susquehanna River into distinct East Shore and West Shore communities. On the East Shore, young professionals gravitate toward Midtown, renowned for its arts scene, historic brick rowhouses, and converted warehouses, as well as Downtown for walkable riverfront living.

Further east, suburban enclaves like Lower Paxton, Paxtonia, and Hummelstown offer quieter residential neighborhoods close to the Route 322 medical corridor leading to Hershey. Across the river on the West Shore in Cumberland County, boroughs like Camp Hill, Lemoyne, Mechanicsburg, and New Cumberland attract residents looking for established tree-lined streets, newer residential subdivisions, and shopping along the Carlisle Pike corridor.

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Housing

Housing styles vary sharply by shoreline and township. Urban neighborhoods like Midtown and Uptown offer historic brick rowhomes, Victorian architecture, and loft conversions in renovated warehouses, though upkeep varies widely.

West Shore boroughs like Camp Hill command a premium for established, well-preserved single-family character homes, while Hampden Township and Mechanicsburg feature expanding master-planned subdivisions with contemporary construction. Eastern Dauphin County suburbs like Lower Paxton, Swatara, and Penbrook offer practical mid-century ranch homes and split-levels convenient to regional medical facilities.

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Getting around

Commutes in the Harrisburg metro generally run twenty to thirty minutes, but daily driving depends heavily on river crossings. Nurses traveling between Cumberland County on the West Shore and East Shore employment hubs face rush-hour bottlenecks on the Susquehanna River bridges.

Major regional arteries include Interstate 81 running through Cumberland County, Interstate 83 linking south toward York and Baltimore, Route 322 feeding directly toward Penn State Health Milton S. Hershey Medical Center, and the Pennsylvania Turnpike (Interstate 76). For regional travel beyond driving, the area is served by Amtrak rail service from downtown Harrisburg and Harrisburg International Airport.

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Food and dining

The local dining landscape centers on Downtown and Midtown, where independent eateries, neighborhood pubs, and Mexican spots like El Sol anchor evening dining. The historic Broad Street Market in Midtown serves as a focal point for fresh produce, prepared regional specialties, and artisan food stalls.

Across the region, craft beer enthusiasts have access to more than twenty regional breweries, while dining options extend west along the Carlisle Pike commercial corridor and east toward resort restaurants around Hershey.

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Outdoors

Outdoor recreation is anchored by the Susquehanna River and its scenic Riverfront Park, which hosts walking and biking paths right alongside downtown. The Capital Area Greenbelt offers a 20-mile continuous multi-use trail looping around the entire city, connecting stops like Italian Lake and Wildwood Park, where visitors encounter wetland wildlife and the seasonal Art in the Wild outdoor installations.

Just north, Fort Hunter Park and Mansion, Detweiler Park, and Boyd Big Tree Preserve Conservation Area provide extensive hiking trails, with Pinchot Park and the Appalachian Trail within short weekend driving range.

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Arts and culture

Harrisburg balances capital-city civic institutions with active grassroots arts. Midtown comes alive during 3rd in the Burg, a monthly community arts celebration featuring open art galleries, music, and local theater productions.

The Sprocket Mural Works project has produced over forty large-scale murals across the city, creating walkable outdoor art trails. City Island hosts minor league baseball with the Harrisburg Senators along with mini-golf overlooking the water.

Additional regional destinations include The State Museum of Pennsylvania, the National Civil War Museum, Hollywood Casino at Penn National Race Course, and nearby Hersheypark entertainment complexes.

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Seasons and weather

Harrisburg experiences a traditional four-season climate characterized by cold winters, humid summers, and crisp transitional months. Spring brings blooming flower displays to Italian Lake and opens up the Capital Area Greenbelt and outdoor events at City Island.

Summers are warm and active along the Susquehanna River with community festivals, though humidity and sudden storm shifts can occur. Autumn provides picturesque foliage across Dauphin and Cumberland counties' rolling hills, while winter brings cold temperatures and periodic snowfall requiring winter driving preparation.

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For families

Families relocating to the area often prioritize school-rich West Shore communities such as Camp Hill and Mechanicsburg, or East Shore suburbs like Paxtonia, Progress, Conewago Township, and Susquehanna Township. The region features numerous family-oriented destinations, including minor league Senators baseball games on City Island, underground cavern tours at Indian Echo Caverns, drive-through safaris at Lake Tobias Wildlife Park, and Hersheypark rides just down Route 322. Neighborhood safety and municipal services vary, prompting many family buyers to seek out established township school districts outside the urban core.

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What locals say

Residents appreciate Harrisburg's accessible scale, manageable traffic outside peak bridge hours, and proximity to major metro hubs like Philadelphia, Baltimore, and Washington, D.C. Locals praise the walkability and charm of Midtown and riverfront recreation. Common frustrations include unpredictable seasonal weather, street-by-street safety variations in older city sectors, and the frequent need to drive across the river or out to suburban retail strips for basic grocery runs and errands.

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