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33 nursing jobs in Lancaster, CA

Lancaster sits in the high desert of the Antelope Valley, about an hour north of Los Angeles. Wide-open skies, Joshua trees, and a rugged Mojave backdrop define the landscape. The revitalized Lancaster Boulevard corridor offers dining and events, while nearby Edwards Air Force Base anchors a strong aerospace community.

Also hiring: Lancaster, PA (88) · Lancaster, SC (15) · Lancaster, TX (8)

Lancaster, CA on the map· Open the live map
Antelope Valley Medical Center workplace
Antelope Valley Medical Center — a workplace named in a current Lancaster postingView Antelope Valley Medical Center →

Find a nursing job in Lancaster

Hiring here: Kaiser Permanente (9) · Star View Behavioral Health, Inc. (5) · Antelope Valley Medical Center (4) · Antelope Valley Medical Center (4) · Antelope Valley Care Center (1) · Anthem Hospice (1)

Antelope Valley Medical Center logo

Antelope Valley Medical Center

Lancaster, CA

  • New grads welcomed
  • RN
  • Day shift
1 / 2

LVN (Part-Time) - Antelope Valley Care Center

Antelope Valley Care Center

Lancaster, CA

  • LPN/LVN
  • Day shift
  • CEU allowance
Antelope Valley Medical Center workplace

Antelope Valley Medical Center

3 open roles · day & rotating shifts · Hospital

Bristol Hospice logo

Bristol Hospice

Lancaster, CA

RN Case Manager

$50–$52/hr

  • RN
  • Tuition reimbursement
Anthem Hospice logo

Anthem Hospice

Lancaster, CA

  • RN
  • Day shift

Antelope Valley Medical Center

Lancaster, CA

  • New grads welcomed
  • RN
  • Night shift
  • Neonatal Intensive Care Unit
PLOV Solutions logo

PLOV Solutions

Lancaster, CA

  • LVN
  • Agency contract
Star View Behavioral Health, Inc. logo

Star View Behavioral Health, Inc.

Lancaster, CA

  • RN
  • 7:00 PM - 7:30 AM
  • CEU allowance
Stars Behavioral Health Group logo

Stars Behavioral Health Group

Lancaster, CA

LVN

$28–$30/hr

  • LVN
  • 12-⁠hour nights
  • CEU allowance
Kaiser Permanente logo

Kaiser Permanente

Lancaster, CA · Health system employer

  • LVN
  • 8-⁠hour evenings
  • Urgent Care
DaVita Kidney Care logo

DaVita Kidney Care

Lancaster, CA

Registered Nurse

$41–$56/hr

  • New grads welcomed · reported
  • RN
  • Flexible shifts including mornings, evenings, weekends, and holidays
  • outpatient dialysis

VITAS Healthcare

Lancaster, CA

Registered Nurse RN

Posted last week

$50–$55/hr

  • RN
  • Day shift

Veterans Health Administration

Lancaster, CA · Health system employer

  • New grads welcomed
  • LPN/LVN
  • Monday - Friday, 7:30am - 4:00pm or 8:00am - 4:30pm

Halcyon Nurse Staffing

Lancaster, CA · Staffing partner

  • RN
  • 12-⁠hour days
  • Travel contract

Focus Staff

Lancaster, CA · Staffing partner

  • RN
  • 10-⁠hour days
  • Travel contract

Antelope Valley Medical Center

Lancaster, CA

  • New grads welcomed
  • RN
  • Day shift
Star View Behavioral Health, Inc. logo

Star View Behavioral Health, Inc.

Lancaster, CA

Registered Nurse

$38–$40/hr

  • RN
  • Evening shift
  • CEU allowance
Kaiser Permanente logo

Kaiser Permanente

Lancaster, CA · Health system employer

  • LPN/LVN
  • Day shift
  • Tuition reimbursement

Focus Staff

Lancaster, CA · Staffing partner

  • RN
  • Travel contract

Antelope Valley Medical Center

Lancaster, CA

  • RN
  • Night shift
  • Per diem
Star View Behavioral Health, Inc. logo

Star View Behavioral Health, Inc.

Lancaster, CA

Registered Nurse

$38–$40/hr

  • RN
  • 12-⁠hour days
  • ADN accepted
Kaiser Permanente logo

Kaiser Permanente

Lancaster, CA · Health system employer

  • LVN
  • Day shift
  • Per diem

Antelope Valley Medical Center

Lancaster, CA

  • New grads welcomed
  • RN
  • Night shift
Star View Behavioral Health, Inc. logo

Star View Behavioral Health, Inc.

Lancaster, CA

LVN / LPT

Posted 6 days ago

  • LVN
  • Night shift
Kaiser Permanente logo

Kaiser Permanente

Lancaster, CA · Health system employer

  • LVN
  • Day shift
  • Per diem
Star View Behavioral Health, Inc. logo

Star View Behavioral Health, Inc.

Lancaster, CA

  • LVN
  • Day shift

Kaiser Permanente

5 open roles · day & per diem shifts · Per Diem

  • LVN
  • Day shift
  • Per diem
  • RN
  • Day shift
  • Per diem

LVN I

Lancaster, CA

$37–$41/hr

  • New grads welcomed
  • LVN
  • 8-⁠hour days
  • Family Medicine-Regular Clinic

Working and living in Lancaster

· 33 open roles

Posted hourly pay

RN
$48/hr median
$39–$48/hr middle half · 14 postings
LVN
$39/hr median
$37–$39/hr middle half · 8 postings

See roles with listed pay

Living costs

Median gross rent
$1,764/mo
Rent and tenant-paid utilities
Median household income
$81,511/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

8 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

1 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • RN19
  • LPN3
  • LVN13

One posting may accept more than one credential.

Shifts listed

  • Days19
  • Nights6
  • Evenings2
  • Rotating2
  • per-diem1

Postings may list several shifts or leave the shift unspecified.

Living in Lancaster

Lancaster offers relocating nurses a distinct High Desert lifestyle framed by the Tehachapi and San Gabriel mountains.

More about life here

As a key healthcare and aerospace hub anchored by Antelope Valley Hospital, Lockheed Martin, and Edwards Air Force Base, the city provides an accessible gateway into Los Angeles County living where spacious yards and standalone single-family homes remain standard. Daily life centers around straightforward commutes along Avenue K and State Route 14, while community leisure thrives around the murals and cafes of The BLVD downtown, trail walks through the Prime Desert Woodland Preserve, and springtime superblooms at the Antelope Valley California Poppy Reserve.

Relocating healthcare professionals generally settle in Quartz Hill or southwest neighborhoods near Erwin Ranch for quieter streets and modern tracts. Moving here involves clear practical tradeoffs: summer temperatures frequently climb into the triple digits, winter brings freezing nights, and late-night social scenes are modest compared to the greater Los Angeles basin.

For clinicians seeking manageable commutes and desert scenery, Lancaster offers a community-focused High Desert post.

Sources
As of Sep 16, 2026
Neighborhoods

Nurses and medical staff relocating to Lancaster generally favor areas west of the freeway. Quartz Hill is a popular established enclave known for quiet residential streets, single-story and two-story homes on larger lots with room for RV parking, and community-oriented living.

Southwest Lancaster, particularly around the Erwin Ranch and Avenue K corridors, offers newer planned residential subdivisions close to Antelope Valley Hospital and retail amenities. Outer neighborhoods such as Del Sur, Fairmont, and custom tracts along West Avenue host more affluent, sprawling properties, while central and downtown Lancaster near The BLVD feature historic districts and more compact urban rental apartments.

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Housing

Lancaster’s housing market primarily consists of detached single-family residences, including classic ranch-style homes built in the mid-to-late twentieth century and newer master-planned developments with multi-bedroom layouts and attached garages. Most residents own their properties, though multi-family apartments and townhomes are concentrated near the city center and along major east-west transit arteries.

Neighborhoods on the west side of the freeway and communities like Quartz Hill command a market premium for their quieter tracts and larger lots, whereas east Lancaster features older, more budget-accessible subdivisions.

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Getting around

Driving is the primary method of transportation throughout the Antelope Valley. Commutes within Lancaster proper are straightforward, averaging approximately twenty minutes to key local employers like Antelope Valley Hospital.

Major local surface thoroughfares like Avenue K, Avenue J, and 10th Street West carry local hospital traffic, while California State Route 14 (the Antelope Valley Freeway) links Lancaster directly south to Palmdale, Santa Clarita, and the broader Greater Los Angeles basin. Parking at medical facilities and shopping centers is generally plentiful and surface-lot based.

Sources
Food and dining

The local dining scene centers around downtown along Lancaster Boulevard (The BLVD), where pedestrians find indie cafes, neighborhood pubs, and weekly gatherings like The BLVD Farmers Market. Local dining spans mom-and-pop bakeries like The Habitual Cook, long-standing Mexican fixtures such as La Paloma, roadside taco trucks, and regional comfort spots like BBQ Bills.

Craft beverage lovers can visit local tasting rooms and microbreweries in Lancaster and neighboring Palmdale, or explore weekend tastings at the Antelope Valley Winery.

Sources
Outdoors

Outdoor life in Lancaster revolves around expansive High Desert landscapes and regional nature preserves. The Antelope Valley California Poppy Reserve draws massive springtime crowds when wild poppies blanket the rolling foothills in bright orange.

Year-round hiking and wildlife spotting take place at the Prime Desert Woodland Preserve, which encompasses over one hundred acres of native oak and chaparral trails. Families and anglers gather at Apollo Community Regional Park for paved walking loops, fishing, and seasonal paddleboat rentals, while Saddleback Butte State Park offers dramatic desert wash trails and views of Joshua trees against the Tehachapi and San Gabriel mountain ranges.

Sources
Arts and culture

Lancaster blends its pioneering aerospace history with an active downtown arts corridor. The city’s aeronautical legacy is preserved through its proximity to Edwards Air Force Base and NASA's Neil A. Armstrong Flight Research Center.

On The BLVD, the Lancaster Museum of Art and History (MOAH) showcases contemporary desert and regional artists alongside public murals, while the Lancaster Performing Arts Center hosts touring theatrical productions, concerts, and community dance performances. Annual valley-wide traditions include the Antelope Valley Fair and community events at the Lancaster National Soccer Center.

Sources
Seasons and weather

Sitting in the western Mojave Desert, Lancaster experiences a semi-arid High Desert climate with extreme seasonal variation unlike coastal Southern California. Summers are scorching, with temperatures regularly surpassing triple digits under clear skies.

Winters turn sharply cold, with freezing overnight temperatures that require residential heating and occasionally bring light snow flurries. Spring and autumn are transitional and pleasant, marked by wildflower blooms and breezy conditions, though shifting desert winds require newcomers to adapt their home cooling and heating routines.

Sources
For families

Families are largely drawn to the western portions of the city and neighboring Quartz Hill, where active neighborhood parks, youth sports at the Lancaster National Soccer Center, and well-regarded elementary options are concentrated. Public education is overseen by the Lancaster School District, Westside Union School District, and Eastside Union School District for primary grades, while the Antelope Valley Union High School District manages upper-grade campuses.

Private schooling options include Lancaster Baptist School and Desert Montessori Academy, alongside higher education at Antelope Valley College. However, families often evaluate neighborhoods carefully due to wide differences in public school performance and localized crime rates between west-side tracts and older eastern sectors.

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What locals say

Residents praise Lancaster for offering spacious single-family homes with sizable yards at price points unattainable in coastal Southern California, alongside close community ties anchored by aerospace and healthcare employers. However, community discussions routinely point out significant tradeoffs: intense seasonal weather swings with blazing summer heat and freezing desert winters, elevated crime rates in certain central and eastern pockets, noticeable economic disparity, and a sleepy nightlife that can leave younger professionals seeking entertainment in larger cities down the freeway.

Sources

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