33 nursing jobs in Lancaster, CA
Lancaster sits in the high desert of the Antelope Valley, about an hour north of Los Angeles. Wide-open skies, Joshua trees, and a rugged Mojave backdrop define the landscape. The revitalized Lancaster Boulevard corridor offers dining and events, while nearby Edwards Air Force Base anchors a strong aerospace community.
Also hiring: Lancaster, PA (88) · Lancaster, SC (15) · Lancaster, TX (8)
Find a nursing job in Lancaster
Hiring here: Kaiser Permanente (9) · Star View Behavioral Health, Inc. (5) · Antelope Valley Medical Center (4) · Antelope Valley Medical Center (4) · Antelope Valley Care Center (1) · Anthem Hospice (1)
- New grads welcomed
- RN
- Day shift
LVN (Part-Time) - Antelope Valley Care Center
Lancaster, CA
- LPN/LVN
- Day shift
- CEU allowance

Antelope Valley Medical Center
3 open roles · day & rotating shifts · Hospital
Antelope Valley Medical Center
3 open roles · day & rotating shifts · Hospital
- RN
- Day shift
- Per diem
- New grads welcomed
- RN
- Day shift
- Rotating shift
- New grads welcomed
- RN
- Night shift
- Neonatal Intensive Care Unit
- LVN
- Agency contract
Registered Nurse
$38/hr
- RN
- 7:00 PM - 7:30 AM
- CEU allowance
Licensed Vocational Nurse III
$39–$43/hr
- LVN
- 8-hour evenings
- Urgent Care
Registered Nurse
$41–$56/hr
- New grads welcomed · reported
- RN
- Flexible shifts including mornings, evenings, weekends, and holidays
- outpatient dialysis
Licensed Vocational Nurse - Ambulatory Care - PACT (CBOC Antelope Valley)
$59,000–$93,000/year
- New grads welcomed
- LPN/LVN
- Monday - Friday, 7:30am - 4:00pm or 8:00am - 4:30pm
Registered Nurse - Emergency Department
$2,716–$3,304/week
- RN
- 12-hour days
- Travel contract
Travel OR RN - Operating Room Registered Nurse
$3,228–$3,294/week
- RN
- 10-hour days
- Travel contract
- New grads welcomed
- RN
- Day shift
Registered Nurse
$38–$40/hr
- RN
- Evening shift
- CEU allowance
Research Nurse IV, LPN / LVN, Clinical Trials
$83,000–$107,000/year
- LPN/LVN
- Day shift
- Tuition reimbursement
- RN
- Travel contract
Lactation Consultant/Educator - Family Resource Center/RN - Part Time/Nights - Req#2117967877
$49–$80/hr
- RN
- Night shift
- Per diem
- LVN
- Day shift
- Per diem
- New grads welcomed
- RN
- Night shift
- LVN
- Day shift
- Per diem
Kaiser Permanente
5 open roles · day & per diem shifts · Per Diem
Kaiser Permanente
5 open roles · day & per diem shifts · Per Diem
- LVN
- Day shift
- Per diem
- LVN
- Day shift
- RN
- Day shift
- Per diem
- New grads welcomed
- LVN
- 8-hour days
- Family Medicine-Regular Clinic
Level III Staff RN - Clinic - Part Time - Chemo Infusion - Lancaster
Lancaster, CA · Posted last week
- RN
- Per diem
Working and living in Lancaster
· 33 open roles
Posted hourly pay
- RN
- $48/hr median
- $39–$48/hr middle half · 14 postings
- LVN
- $39/hr median
- $37–$39/hr middle half · 8 postings
Living costs
- Median gross rent
- $1,764/mo
- Rent and tenant-paid utilities
- Median household income
- $81,511/yr
- All local households, not nurse pay
New to our board this week
1 current postings first appeared here in the past seven days.
Credentials accepted
- RN19
- LPN3
- LVN13
One posting may accept more than one credential.
Shifts listed
- Days19
- Nights6
- Evenings2
- Rotating2
- per-diem1
Postings may list several shifts or leave the shift unspecified.
Living in Lancaster
Lancaster offers relocating nurses a distinct High Desert lifestyle framed by the Tehachapi and San Gabriel mountains.
More about life hereShow less
As a key healthcare and aerospace hub anchored by Antelope Valley Hospital, Lockheed Martin, and Edwards Air Force Base, the city provides an accessible gateway into Los Angeles County living where spacious yards and standalone single-family homes remain standard. Daily life centers around straightforward commutes along Avenue K and State Route 14, while community leisure thrives around the murals and cafes of The BLVD downtown, trail walks through the Prime Desert Woodland Preserve, and springtime superblooms at the Antelope Valley California Poppy Reserve.
Relocating healthcare professionals generally settle in Quartz Hill or southwest neighborhoods near Erwin Ranch for quieter streets and modern tracts. Moving here involves clear practical tradeoffs: summer temperatures frequently climb into the triple digits, winter brings freezing nights, and late-night social scenes are modest compared to the greater Los Angeles basin.
For clinicians seeking manageable commutes and desert scenery, Lancaster offers a community-focused High Desert post.
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Neighborhoods
Nurses and medical staff relocating to Lancaster generally favor areas west of the freeway. Quartz Hill is a popular established enclave known for quiet residential streets, single-story and two-story homes on larger lots with room for RV parking, and community-oriented living.
Southwest Lancaster, particularly around the Erwin Ranch and Avenue K corridors, offers newer planned residential subdivisions close to Antelope Valley Hospital and retail amenities. Outer neighborhoods such as Del Sur, Fairmont, and custom tracts along West Avenue host more affluent, sprawling properties, while central and downtown Lancaster near The BLVD feature historic districts and more compact urban rental apartments.
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Housing
Lancaster’s housing market primarily consists of detached single-family residences, including classic ranch-style homes built in the mid-to-late twentieth century and newer master-planned developments with multi-bedroom layouts and attached garages. Most residents own their properties, though multi-family apartments and townhomes are concentrated near the city center and along major east-west transit arteries.
Neighborhoods on the west side of the freeway and communities like Quartz Hill command a market premium for their quieter tracts and larger lots, whereas east Lancaster features older, more budget-accessible subdivisions.
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Getting around
Driving is the primary method of transportation throughout the Antelope Valley. Commutes within Lancaster proper are straightforward, averaging approximately twenty minutes to key local employers like Antelope Valley Hospital.
Major local surface thoroughfares like Avenue K, Avenue J, and 10th Street West carry local hospital traffic, while California State Route 14 (the Antelope Valley Freeway) links Lancaster directly south to Palmdale, Santa Clarita, and the broader Greater Los Angeles basin. Parking at medical facilities and shopping centers is generally plentiful and surface-lot based.
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Food and dining
The local dining scene centers around downtown along Lancaster Boulevard (The BLVD), where pedestrians find indie cafes, neighborhood pubs, and weekly gatherings like The BLVD Farmers Market. Local dining spans mom-and-pop bakeries like The Habitual Cook, long-standing Mexican fixtures such as La Paloma, roadside taco trucks, and regional comfort spots like BBQ Bills.
Craft beverage lovers can visit local tasting rooms and microbreweries in Lancaster and neighboring Palmdale, or explore weekend tastings at the Antelope Valley Winery.
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Outdoors
Outdoor life in Lancaster revolves around expansive High Desert landscapes and regional nature preserves. The Antelope Valley California Poppy Reserve draws massive springtime crowds when wild poppies blanket the rolling foothills in bright orange.
Year-round hiking and wildlife spotting take place at the Prime Desert Woodland Preserve, which encompasses over one hundred acres of native oak and chaparral trails. Families and anglers gather at Apollo Community Regional Park for paved walking loops, fishing, and seasonal paddleboat rentals, while Saddleback Butte State Park offers dramatic desert wash trails and views of Joshua trees against the Tehachapi and San Gabriel mountain ranges.
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Arts and culture
Lancaster blends its pioneering aerospace history with an active downtown arts corridor. The city’s aeronautical legacy is preserved through its proximity to Edwards Air Force Base and NASA's Neil A. Armstrong Flight Research Center.
On The BLVD, the Lancaster Museum of Art and History (MOAH) showcases contemporary desert and regional artists alongside public murals, while the Lancaster Performing Arts Center hosts touring theatrical productions, concerts, and community dance performances. Annual valley-wide traditions include the Antelope Valley Fair and community events at the Lancaster National Soccer Center.
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Seasons and weather
Sitting in the western Mojave Desert, Lancaster experiences a semi-arid High Desert climate with extreme seasonal variation unlike coastal Southern California. Summers are scorching, with temperatures regularly surpassing triple digits under clear skies.
Winters turn sharply cold, with freezing overnight temperatures that require residential heating and occasionally bring light snow flurries. Spring and autumn are transitional and pleasant, marked by wildflower blooms and breezy conditions, though shifting desert winds require newcomers to adapt their home cooling and heating routines.
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For families
Families are largely drawn to the western portions of the city and neighboring Quartz Hill, where active neighborhood parks, youth sports at the Lancaster National Soccer Center, and well-regarded elementary options are concentrated. Public education is overseen by the Lancaster School District, Westside Union School District, and Eastside Union School District for primary grades, while the Antelope Valley Union High School District manages upper-grade campuses.
Private schooling options include Lancaster Baptist School and Desert Montessori Academy, alongside higher education at Antelope Valley College. However, families often evaluate neighborhoods carefully due to wide differences in public school performance and localized crime rates between west-side tracts and older eastern sectors.
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What locals say
Residents praise Lancaster for offering spacious single-family homes with sizable yards at price points unattainable in coastal Southern California, alongside close community ties anchored by aerospace and healthcare employers. However, community discussions routinely point out significant tradeoffs: intense seasonal weather swings with blazing summer heat and freezing desert winters, elevated crime rates in certain central and eastern pockets, noticeable economic disparity, and a sleepy nightlife that can leave younger professionals seeking entertainment in larger cities down the freeway.