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Registered Nurse (RN)- Ambulatory Care, Upstate

Prisma Health

Greenville, South Carolina

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RNSign-on bonus

Posted Aug 8, 2026 · Last seen active Aug 9, 2026

What this might mean for you

Prisma Health is an academic medical center — teaching floors, residents in the halls, and more sub-specialties to grow into. The schedule rotates — ask early how far out they post it; that answer tells you a lot.

What the posting states

Shift
Rotating

About this role

Show full description
Inspire health. Serve with compassion. Be the difference. Job Summary Provides routine, standardized nursing care for patients under the supervision of the physician. Are you an Experienced RN interested in the Ambulatory Service Line? APPLY HERE to learn about open positions in our Prisma Health Ambulatory Practices throughout the Upstate, SC area. Prisma Health offers a $7500 sign-on bonus for eligible full-time direct care positions. We also offer $5,250 student tax-free loan repayment (per year). Moving to South Carolina? Ask about our relocation assistance program. READ MORE about our benefits. Once you apply, our Talent Acquisition Team will reach out and schedule a time to discuss the many exciting opportunities Prisma Health has to offer. Not ready to apply or want to learn more about Prisma Health? Engage with our team through unparalleled access to a live person at our monthly Experienced RN/LPN Q&A Events. Click here to find a convenient date and time. Essential Functions All team members are expected to be knowledgeable and compliant with Prisma Health's values: Inspire health. Serve with compassion. Be the difference. Provides direct nursing care within established policies, procedures, and protocols and in accordance with regulatory scope of practice and Board of Nursing in the state in which work is performed. Provides patient care based upon individualized plan of care including patient's physical, emotional, cultural, spiritual, psychosocial, and educational needs. Utilizes the unique knowledge, skills, and competencies required in ambulatory care nursing practice to promote wellness, restore health, and address health-related situational problems. Assesses patients’ needs and applies current ambulatory care nursing knowledge and evidence-based nursing practice when developing an individualized plan of care for each patient. Administers prescribed medications and treatments in accordance with approved nursing protocol. Coordinates, and documents patient care in a knowledgeable, skillful, and consistent manner. This includes patient assessment, education, medication administration, treatments, and patient safety. Delegates tasks and duties to healthcare team members in accordance with the patient’s needs and the team member’s capabilities and qualifications. Adhere to infection control and safety protocols. Communicates appropriate information regarding patient condition or concerns to other health care team members. Educates patients and families to appropriately perform any recommended post-visit self-care tasks. Integrates patient and family education throughout the delivery of care so they may make informed health related decisions. Provides a compassionate and therapeutic environment for patients and their families. Serves as a role model and participates in educating and mentoring other members of the care team. Attends department and organization meetings. Completes annual and as needed compliance training. Practices safe, efficient use of supplies and resources. Maintains a clean, safe, and caring environment for patients, family and other staff. Assumes responsibility for one’s own professional development and continuing education. May serve as a preceptor, unit champion, or participate in shared governance. Adheres to all compliance, policies and procedures of the organization. Performs other duties as assigned. Supervisory/Management Responsibility This is a non-management job that will report to a supervisor, manager, director or executive. Minimum Requirements Education - Associate degree in Nursing (ADN). BSN preferred. Experience - No experience is required. In Lieu Of In lieu of an associate’s degree in nursing (ADN), will accept an RN diploma or certificate with a current RN compact/multistate license recognized by the NCSBN Compact State or a license to practice as an RN in the state the team member is working. Required Certifications, Registrations, Licenses Holds a current RN compact/multistate license recognized by the NCSBN Compact State or is licensed to practice as an RN in the state the team member is working. Knowledge, Skills And Abilities NA Work Shift Variable (United States of America) Location Prisma Health Corporate Office Facility 7001 Corporate Department 70019061 Talent Acquisition Share your talent with us! Our vision is simple: to transform healthcare for the benefits of the communities we serve. The transformation of healthcare requires talented individuals in every role here at Prisma Health.

Skills for this role

Patient CareMedication AdministrationPatient Assessment

Requirements

  • Education - Associate degree in Nursing (ADN). BSN preferred. Experience - No experience is required.

Benefits

  • $7500 sign-on bonus for eligible full-time direct care positions
  • $5,250 student tax-free loan repayment per year
  • Relocation assistance program

About the employer

Prisma Health logo
Prisma Health
Academic Medical Center

Prisma Health is a large South Carolina-based healthcare system with nearly 32,000 team members, serving communities across the state including its Columbia market. The organization describes itself as being on a journey to transform the healthcare experience for patients and…

2.4 Google rating

What reviewers appreciate

  • Large health system with approximately 32,000 team members, offering diverse nursing career paths and settings
  • Remote nursing positions available for South Carolina residents, including post-discharge outreach roles
  • Strong stated commitment to diversity, inclusion, and valuing different backgrounds and lived experiences

What reviewers flag

  • Extensive compliance and policy requirements may create administrative burden for nursing staff
  • Large organizational size of nearly 32,000 employees may lead to bureaucratic challenges or feeling disconnected from leadership
  • Detailed employee review data and specific nurse satisfaction metrics were not available in the provided research sources
compassionateteam-orienteddiverseinclusivemission-driventransformative

Living in Greenville, SC

Greenville blends Southern charm with a revitalized downtown anchored by Falls Park on the Reedy River. The Main Street corridor offers walkable dining, breweries, and weekly farmers markets. Nestled in the foothills of the Blue Ridge Mountains, Greenville delivers mild four-season weather and an increasingly active healthcare corridor.

Map showing the location of Greenville, SC
Greenville, SC on the map · © Mapbox © OpenStreetMap· Open the live map
Metro price level · Greenville area
93.3
7% below the national average
Median gross rent
$1,312/mo
rent and tenant-paid utilities

U.S. Bureau of Economic Analysis · 2024 metro Regional Price Parities · Census ACS 2024

Browse open roles in Greenville

Worth asking

The posting doesn’t answer these. Good ones to ask a recruiter or in the interview.

  • Can you walk me through the base pay range, differentials, and sign-on bonus repayment terms?
  • What should I expect for weekly hours, weekend, holiday, call, and rotation?
  • What orientation, preceptor time, and ongoing unit support are included?
  • How are patient load, floating, and staffing support handled day to day?
Open the full posting report

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