59 nursing jobs in Easley, SC
Just 12 miles down US-123 from Greenville’s hospital networks, Easley pairs Blue Ridge foothills living with established neighborhoods like Albertson Estates and historic Arial Mill bungalows. Decompress post-shift along the 8.5-mile Doodle Trail, grab bites in The Silos communal courtyard, and enjoy generous lot sizes within an easy drive of regional trauma centers.
Find a nursing job in Easley
Hiring here: 110 Prisma Health-Upstate (36) · Prisma Health (14) · 121 Prisma Health-University Medical Group (5) · Presbyterian Communities of South Carolina (2) · ATC Healthcare Services of Georgia (1) · Interim HealthCare of The Upstate (1)

Prisma Health
14 open roles
Prisma Health
14 open roles
- NP
- RN
- Rotating shift
- Per diem
- RN
- Night shift
- Per diem
- RN
- Day shift
- RN
- Night shift
- Per diem
- RN
- Day shift
- Per diem
- RN
- Night shift
- RN
- Night shift
- RN
- Day shift
- Per diem
- RN
- Day shift
- RN
- Rotating shift
- Per diem
- RN
- Day shift
- Agency contract
- RN
- Per diem
- Compact license OK
- RN
- Night shift
- Compact license OK
Interim HealthCare of The Upstate
Easley, SC
Registered Nurse (RN) - Home Health
$70,000–$90,000/year
- RN
- Compact license OK
- Tuition reimbursement
- LPN
- 12-hour days
- Tuition reimbursement
- NP
- Variable (United States of America)
Certified Nursing Assistant Progressive ICU/ICU full time nights
Posted last week
- New grads welcomed
- CNA
- Night shift
- RN
- 12-hour nights
- Travel contract
- LPN
- 12-hour nights
- Tuition reimbursement
Anesthetist - Easley
Posted 5 days ago
- CRNA
- Rotating shift
Certified Nursing Assistant Progressive ICU/ICU Full Time Days
Posted last week
- New grads welcomed
- CNA
- Day shift
Anesthetist - Easley
Posted 5 days ago
- CRNA
- Rotating shift
Nursing Specialty Tech-ER Full Time Variable
Posted last week
- New grads welcomed
- RN
- Rotating shift
Registered Nurse (RN)- Ambulatory, Heritage Pediatrics and Internal Medicine, FT, Day
Posted last week
- New grads welcomed
- RN
- Day shift
- New grads welcomed
- RN
- Day (United States of America)
- Compact license OK
110 Prisma Health-Upstate
21 open roles · Hospital
110 Prisma Health-Upstate
21 open roles · Hospital
Patient Observer
Easley, SC · Posted last week
- New grads welcomed
- CNA
- Day (United States of America)
- RN
- Variable
- Per diem
Nursing Assistant Cert
Easley, SC
- New grads welcomed
- CNA
- Day (United States of America)
- New grads welcomed
- RN
- Variable (United States of America)
- Compact license OK
- RN
- Night (United States of America)
- ICU Medical
Nursing Assistant Cert
Easley, SC
- New grads welcomed
- Day (United States of America)
- RN
- Night shift
- Compact license OK
- New grads welcomed
- RN
- Night (United States of America)
- Compact license OK
- New grads welcomed
- RN
- Night shift
- Short Stay Surgical
- RN
- Night (United States of America)
- Compact license OK
- RN
- Day (United States of America)
- Gastrointestinal Diagnostic Lab
- New grads welcomed
- CNA
- Night
- ICU Progressive Care
- RN
- Day
- Compact license OK
- RN
- Night (United States of America)
- Per diem
- RN
- Day
- Compact license OK
- RN
- Day (United States of America)
- Compact license OK
- RN
- Night
- Per diem
- RN
- Variable (United States of America)
- Recovery Room
- RN
- Day (United States of America)
- Compact license OK
- RN
- Night (United States of America)
- ICU Medical
- New grads welcomed
- RN
- Variable
- Compact license OK
Working and living in Easley
· 59 open roles
New to our board this week
2 current postings first appeared here in the past seven days.
Credentials accepted
- CRNA2
- NP2
- RN43
- LPN2
- CNA8
One posting may accept more than one credential.
Shifts listed
- Nights23
- Days21
- Rotating12
- per-diem1
Postings may list several shifts or leave the shift unspecified.
Living in Easley
Easley offers healthcare professionals a grounded Upstate South Carolina base, bridging the energetic medical corridor of Greenville with the peaceful foothills of Pickens County.
More about life hereShow less
Positioned roughly 12 miles down US-123 from Greenville's major hospital networks, Easley functions as a self-sufficient community rather than a sleepy bedroom suburb. Shift workers can unwind along the 8.5-mile Doodle Trail or grab post-shift coffee at Old Post Coffee Shop and evening bites at The Silos, where Silos Brewing and local food stalls gather in a walkable communal courtyard.
Housing spans established suburban enclaves like Albertson Estates and Bellestone, historic mill residences in Arial Mill, and newer builds near southern Pickens County schools. The trade-offs center on car dependency, commercial congestion along Calhoun Memorial Highway, and having to drive into Greenville for specialized shopping like Trader Joe's.
However, for nurses seeking approachable neighborhood living, spacious lots, and swift access to Blue Ridge trails and regional trauma centers alike, Easley offers a balanced, community-centered alternative.
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Neighborhoods
Easley features a distinct mix of established subdivisions, historic mill areas, and rural peripheral acreage. Albertson Estates, Bellestone, and Botany Park are well-regarded established neighborhoods developed in the 1990s and 2000s that feature mature trees, traditional family layouts, and mid-tier single-family homes.
Arial Mill offers historic mill-village character with older bungalows that require more structural upkeep, while the Crestview Road area hosts interconnected communities like Kingsberry, MiddleCreek, and Smithfields surrounding the country club. Southeast toward Anderson County, the unincorporated Powdersville corridor and developments like Avondale Heights, Huntington North, and Yorkwood feature newer single-story brick ranches and larger executive homes.
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Housing
Housing stock in Easley spans multiple architectural eras, ranging from compact historic mill houses near Arial Mill to 1990s and 2000s brick ranches and two-story homes on generous parcels in Albertson Estates and Bellestone. Active production builders have added modern tract subdivisions with tighter lot lines near southern school corridors, while the outlying fringes feature semi-rural properties on one- to five-acre lots operating on private well and septic systems.
Powdersville to the southeast commands premium pricing for larger custom properties.
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Getting around
Commuting from Easley is strictly vehicle-dependent, as the area lacks regional public transit connections to major medical centers. The town sits roughly 12 miles west of downtown Greenville, translating to an approximate 20- to 25-minute drive via US-123 (Calhoun Memorial Highway), where Greenville's primary hospital systems are concentrated.
Commuters traveling south toward Anderson County or I-85 rely on Route 153, which experiences heavy morning and evening traffic around commercial retail clusters.
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Food and dining
Easley's food culture centers around a revitalized downtown core and The Silos, a communal gathering hub housing Silos Brewing, Inky’s Philadelphia Cheesesteaks, Indigo Kitchen, and Loaded Gourmet Tater Bar, alongside Southern Fuel Coffee & Eats and You Drive Me Glazy Donuts. Downtown morning spots include Old Post Coffee Shop in a restored 1940s postal building and Iron Horse Steamers for house-made bagels.
Evening choices range from Colombian-style burgers at Tropical Burger and craft pours at The Pint Station to Italian dishes at Amici's, seasonal fine dining at Element in a converted home, and lively crowds at Mr. Cactus Mexican Restaurant on Calhoun Memorial Highway.
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Outdoors
The centerpiece of Easley's outdoor recreation is the Doodle Trail, an 8.5-mile rails-to-trails paved greenway running between downtown Easley and Pickens that attracts runners, cyclists, and dog walkers. Within town, Nalley Brown Nature Park offers forested hiking trails, while Molly Cooper Park sits along the banks of the Saluda River with access for fishing and camping.
For broader excursions, the Blue Ridge foothills, Table Rock State Park, and Lake Keowee are located within a short drive to the north and west.
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Arts and culture
Community gatherings frequently revolve around downtown Easley's outdoor amphitheater, water-feature park, and regular seasonal events. Community theater thrives at the Foothills Playhouse, while the Greenville-Pickens Speedway hosts the annual Upper South Carolina State Fair every September.
Easley also has a deep youth sports legacy, hosting the Senior League World Series and regional tournaments at the JB Owens Sports Complex, while local nightlife includes trivia and live music at The Pint Station, Amici's, and Hideout Bar and Grill.
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Seasons and weather
Located in the Upstate foothills, Easley experiences a temperate four-season climate characterized by generally mild winters with occasional light freezes and long, warm summers with notable humidity. The shoulder seasons in spring and autumn bring extended stretches of moderate weather, allowing year-round use of the Doodle Trail and outdoor dining at The Silos.
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For families
Families are drawn to Easley largely by neighborhood stability, active youth athletics, and neighborhood-centric schooling. The southern sector of the city clusters multiple campuses including Forest Acres, East End, Hunt Meadows, Crosswell, and West End elementary schools, which feed into Richard H. Gettys Middle School and Easley High School, while Powdersville schools serve the Anderson County boundary.
Family recreation centers on the eight-field JB Owens Sports Complex along Brushy Creek, baseball games at Woodside Park, and open-air play along the Doodle Trail.
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What locals say
Residents describe Easley as a friendly, relaxed community that functions as its own independent town rather than a generic bedroom suburb. Locals appreciate that everyday essentials like grocery stores, clinics, and family dining are readily available without having to drive into Greenville.
The primary criticisms involve commercial strip congestion along Calhoun Memorial Highway, car dependency, and the need to commute into Greenville for specialty retailers such as Costco or Trader Joe's.