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31 nursing jobs in Holyoke, MA

Post-shift life in Holyoke blends historic canal-district roots with rich cultural energy. Grab morning pastries at local Puerto Rican bakeries, catch breakfast at Rusty’s, or unwind at Delaney House. Between the legendary St. Patrick’s Parade Weekend and seasonal Night Markets at Armour Yard, Holyoke offers nurses a distinctive, tight-knit community to call home.

Holyoke, MA on the map· Open the live map
Tapestry workplace
Tapestry — a workplace named in a current Holyoke postingView Tapestry →

Find a nursing job in Holyoke

Hiring here: Valley Springs Behavioral Health Hospital (12) · American Traveler (2) · Holyoke Medical Center (2) · Lifepoint Health (2) · Activate Care (1) · Center for Human Development (1)

Tapestry logo

Tapestry

Holyoke, MA

  • NP
  • Tuition reimbursement
Valley Springs Behavioral Health Hospital workplace

Valley Springs Behavioral Health Hospital

10 open roles · Behavioral Health

Registered Nurse (RN) Behavioral Health

Holyoke, MA · Posted 3 days ago

  • RN
  • Per diem

Registered Nurse (RN) Forensic Unit

Holyoke, MA · Posted 6 days ago

  • RN
  • 8-⁠hour days

Licensed Practical Nurse (LPN) Forensic Unit

Holyoke, MA · Posted last week

$30–$45

  • LPN
  • 8-⁠hour nights

Registered Nurse (RN) Forensic Unit

Holyoke, MA · Posted last week

  • RN
  • 8-⁠hour evenings

Registered Nurse (RN) Forensic Unit

Holyoke, MA · Posted last week

  • RN
  • 8-⁠hour days

Registered Nurse, (RN) Forensic Unit

Holyoke, MA · Posted last week

  • RN
  • 8-⁠hour shifts
  • Per diem
  • RN
  • 8-⁠hour nights
  • Forensic Unit

Registered Nurse (RN) Behavioral Health

Holyoke, MA · Posted last week

  • RN
  • 12-⁠hour nights

Licensed Practical Nurse (LPN) Forensic Unit

Holyoke, MA · Posted last week

$30–$45

  • LPN
  • 8-⁠hour shifts
  • Per diem

Registered Nurse (RN) Behavioral Health

Holyoke, MA · Posted last week

  • RN
  • 8-⁠hour nights
Holyoke Medical Center logo

Holyoke Medical Center

Holyoke, MA

  • RN
  • Day shift
  • Tuition reimbursement
RegalCare logo

RegalCare

Holyoke, MA

MDS Coordinator

$46–$52/hr

  • Sign-on bonus
  • RN

Center for Human Development

Holyoke, MA

  • RN
RegalCare at Holyoke logo

RegalCare at Holyoke

Holyoke, MA

RN/LPN

$37–$55/hr

  • New grads welcomed
  • RN
  • Rotating shift

Center for Human Development (CHD)

Holyoke, MA

Registered Nurse

From $85,000/year

  • RN

Healthcare employer

Holyoke, MA

  • New grads welcomed
  • RN/LPN
  • Rotating shift

JobsInMass.com

Holyoke, MA

  • RN
  • 8-⁠hour 8 hour
Valley Springs Behavioral Health Hospital logo

Valley Springs Behavioral Health Hospital

Holyoke, MA

  • RN
  • 12-⁠hour nights
  • Per diem

Activate Care

Holyoke, MA

  • NP
  • Evening shift
Dolphin Solutions Inc logo

Dolphin Solutions Inc

Holyoke, MA

  • RN
  • Evening (3p-11:30p) (every other weekend/every other holiday)
  • Agency contract
Lifepoint Health logo

Lifepoint Health

Holyoke, MA

  • RN
  • 8-⁠hour nights
  • Forensic Unit
Elara Caring logo

Elara Caring

Holyoke, MA

  • Sign-on bonus
  • LPN/LVN
  • Day shift
  • Tuition reimbursement

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Holyoke, MA

RN/LPN

$37–$55/hr

  • New grads welcomed
  • RN
  • Rotating shift
American Traveler logo

American Traveler

Holyoke, MA · Staffing partner

Travel RN - Psychiatric

Posted 3 days ago

$2,315/week

  • RN
  • Travel contract
Vibra Travels LLC logo

Vibra Travels LLC

Holyoke, MA · Staffing partner

RN - Psych

$2,634/week

  • RN
  • Travel contract

Holyoke Medical Center

Holyoke, MA

  • RN
  • 12-⁠hour evenings
  • Tuition reimbursement
Valley Springs Behavioral Health Hospital logo

Valley Springs Behavioral Health Hospital

Holyoke, MA

  • Sign-on bonus
  • LPN
  • Ratio 1:6–1:8
  • 12-⁠hour days
Lifepoint Health logo

Lifepoint Health

Holyoke, MA

  • RN
  • Schedule: 8-⁠Hour Shifts
  • Per diem
American Traveler logo

American Traveler

Holyoke, MA · Staffing partner

  • RN
  • Ratio 1:8
  • 12-⁠hour nights

Holyoke Medical Center

Holyoke, MA

Registered Nurse

$37–$62/hr

  • RN
  • 12-⁠hour days
  • Tuition reimbursement

Working and living in Holyoke

· 31 open roles

Posted hourly pay

RN
$43/hr median
$37–$43/hr middle half · 11 postings

See roles with listed pay

Living costs

Median gross rent
$1,021/mo
Rent and tenant-paid utilities
Median household income
$53,605/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

3 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

4 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • NP2
  • RN25
  • LPN5
  • LVN1

One posting may accept more than one credential.

Shifts listed

  • Nights7
  • Days6
  • Evenings4
  • per-diem4
  • Rotating3

Postings may list several shifts or leave the shift unspecified.

Living in Holyoke

Holyoke offers relocating healthcare professionals a distinct blend of historic industrial character and direct access to Pioneer Valley landscapes.

More about life here

Anchored along the Connecticut River, the city was once the world’s paper capital, leaving behind a striking grid of brick mills, canals, and grand Victorian architecture. Today, clinicians at Holyoke Medical Center benefit from uncomplicated commutes via Interstate 91, which easily connects south to Springfield and north to college communities like Northampton.

Off-shift hours can be spent walking the trails around Ashley Reservoir, hiking Mount Tom State Reservation, or exploring the canalwalk at Holyoke Heritage State Park. The city's cultural richness is felt through vibrant Puerto Rican dining, community gatherings at Beyond Armour Yard, and the celebrated St. Patrick’s Parade.

However, relocation requires clear eyes regarding urban tradeoffs: Holyoke grapples with higher-than-average crime rates in central areas like South Holyoke, an underperforming public school system, and harsh winter snowstorms. Nurses seeking calm typically focus their home search on the Highlands and Mount Tom foothills, or settle in adjacent towns while enjoying Holyoke's authentic grit and natural setting.

Sources
As of Sep 16, 2026
Neighborhoods

Prospective residents in Holyoke generally look across distinct pockets ranging from walkable urban blocks along High Street downtown to quieter, leafy residential enclaves nestled near the Mount Tom foothills and the Highlands. Closer to the core, historic Victorians and converted spaces offer convenient access to city amenities, while outer neighborhoods lean toward traditional single-family layouts with lower density.

Relocating healthcare professionals who desire suburban or college-town settings also frequently cross-shop neighboring communities like Easthampton, Northampton, and West Springfield for easy commutes back into Holyoke.

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Housing

Housing options in Holyoke range from historic multi-family apartments and converted brick industrial properties in the urban core to older Victorian homes and traditional single-family residences along winding streets further out. Neighborhoods near the Mount Tom foothills and the Highlands are regarded as more established residential areas, whereas downtown rentals cater to residents wanting walkability.

Prospective buyers and renters should note that properties immediately adjacent to the Connecticut River carry seasonal flood considerations.

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Getting around

Holyoke is well-positioned along Interstate 91, which serves as the primary north-south artery connecting directly to Interstate 391 and the Massachusetts Turnpike (I-90), placing Springfield roughly ten miles south. For clinical staff based at Holyoke Medical Center or traveling between Pioneer Valley health systems, highway connections are direct and regional traffic is manageable compared to eastern Massachusetts.

Downtown and regional destinations generally feature straightforward vehicle parking, though daily errands and hospital shift commuting remain predominantly car-dependent despite regional transit coverage.

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Food and dining

Holyoke’s culinary landscape showcases strong cultural variety, marked especially by authentic Puerto Rican bakeries and eateries reflecting the city’s heritage. Longtime local favorites anchor morning and casual dining, such as Rusty's for classic breakfast plates and Capri for casual bites.

For upscale dinners and evenings out, residents gravitate toward spots like Delaney House and Tavern on the Hill, while downtown community gatherings like the seasonal Night Market at Armour Yard and the opening of Cornucopia Natural Wellness Market supply fresh food, artisan vendors, and social energy.

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Outdoors

Outdoor recreation is a major draw for Holyoke residents, anchored by Mount Tom State Reservation, where multi-use trails deliver panoramic views across the Connecticut River Valley. Nearby Mount Holyoke Range State Park and Skinner State Park, featuring the historic Mount Holyoke Summit House, offer scenic hiking and mountain biking.

Within the city, Ashley Reservoir provides tranquil gravel paths favored for jogging and walking, while Holyoke Heritage State Park allows visitors to stroll along the historic canal network and riverfront.

Sources
Arts and culture

Holyoke celebrates its storied manufacturing past through sites like the Wistariahurst Museum, an ornate Victorian mansion showcasing the city’s paper-mill era, and the Children's Museum at Holyoke along the canal district. The city comes alive with major cultural celebrations, including the renowned St. Patrick’s Parade Weekend and the Fiestas Patronales de Holyoke honoring its Puerto Rican community.

Community life also revolves around events like Holyoke Pride and open-air gatherings at Beyond Armour Yard.

Sources
Seasons and weather

Winters in Holyoke are demanding, typically bringing freezing temperatures and more than four feet of snow that require diligent seasonal maintenance and cautious driving on icy hills. Spring transitions into lush, green conditions that lead to warm, active summers filled with canal-side festivals and outdoor recreation.

Autumn is arguably the region's showcase season, delivering crisp, clear days and vibrant foliage displays visible across Mount Tom and the wider Pioneer Valley.

Sources
For families

For families, Holyoke offers engaging civic amenities such as the Children’s Museum at Holyoke, neighborhood pocket parks, and easy access to nature trails at Ashley Reservoir. However, the Holyoke Public School District faces documented academic challenges and lower performance ratings, prompting some local families to utilize regional charter schools or consider surrounding towns.

Safety conditions vary significantly by neighborhood, with quieter residential areas like the Highlands offering a much more tranquil environment than central urban corridors.

Sources
What locals say

Residents describe Holyoke as an authentic, resilient city defined by a proud industrial heritage, tight-knit community bonds, and deep cultural diversity. Locals praise the outstanding access to Pioneer Valley nature, the emerging downtown energy, and more manageable living expenses than Boston or coastal New England.

However, community discussions candidly highlight ongoing challenges, including elevated property and violent crime rates, visible poverty, drug recovery issues in urban pockets like South Holyoke, underfunded public schools, and difficult winter road conditions.

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