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95 nursing jobs in San Luis Obispo, CA

Framed by volcanic morros like Bishop Peak and the Pacific coast, San Luis Obispo offers nurses a restorative Central Coast pace. Decompress hiking Cerro San Luis or grabbing tri-tip at the Thursday night farmers' market. With living costs about 9% above the national average, SLO pairs clinical career growth with unhurried coastal living.

San Luis Obispo, CA on the map· Open the live map
French Hospital Medical Center workplace
French Hospital Medical Center — a workplace named in a current San Luis Obispo postingView French Hospital Medical Center →

Find a nursing job in San Luis Obispo

Hiring here: Adventist Health (47) · Wellpath (8) · CommonSpirit Health (4) · French Hospital Medical Center (4) · HealthForce Healthcare (3) · Dignity Health (2)

French Hospital Medical Center

SAN LUIS OBISPO, CA

Staff Nurse II

Posted last week

$52–$77/hr

  • RN
1 / 2

Oncology Hematology Nurse Practitioner

Pacific Central Coast Health Center

San Luis Obispo, CA · Posted 4 days ago

$144–$214/hr

  • NP
1 / 2

Certified Medical Assistant

Primary Care - Private Practice SLO logoPrimary Care - Private Practice SLO

San Luis Obispo, CA

$25/hr

  • Day shift

French Hospital Medical Center

SAN LUIS OBISPO, CA

ED Tech - Clinical Secretary

Posted last week

$25–$31/hr

  • CNA

Pacific Central Coast Health Center

San Luis Obispo, CA

RN

$57–$87/hr

  • RN
  • Day shift

French Hospital Medical Center

San Luis Obispo, CA

  • New grads welcomed
  • RN

French Hospital Medical Center

SAN LUIS OBISPO, CA

Assistant Nurse Manager

Posted last week

$59–$89/hr

  • RN

A T Still University of Health Sciences

San Luis Obispo, CA

  • DNP/RN
  • Day shift
Option Care Health logo

Option Care Health

San Luis Obispo, CA

  • RN

Central Coast Home Health & Hospice

San Luis Obispo, CA

  • Sign-on bonus
  • RN
  • Day shift
Compassionate Care Home Health Agency logo

Compassionate Care Home Health Agency

San Luis Obispo, CA

  • RN
Adventist Health Sierra Vista logo

Adventist Health Sierra Vista

San Luis Obispo, CA

  • RN
  • Day shift
  • Travel contract

Serene Aftercare, Concierge Nursing

San Luis Obispo, CA

Concierge RN

Posted 2 days ago

$400 - $600 a day

  • RN
  • Per diem
Omega Home Health Care Services, Inc. logo

Omega Home Health Care Services, Inc.

San Luis Obispo, CA

  • RN
  • Per diem
Adventist Health logo

Adventist Health

San Luis Obispo, CA · Health system employer

  • NP
  • Day shift
  • Per diem
IQVIA logo

IQVIA

San Luis Obispo, CA

Flex Nurse Educator - Fresno, CA

$80,000–$85,000/year

  • RN
  • Compact license OK
Dignity Health logo

Dignity Health

San Luis Obispo, CA

RN

Posted last week

$52–$77/hr

  • New grads welcomed
  • RN
Wellpath logo

Wellpath

San Luis Obispo, CA

Nurse Practitioner

Posted last week

  • NP
  • Rotating shift
  • Per diem
DaVita Kidney Care logo

DaVita Kidney Care

San Luis Obispo, CA

Registered Nurse

$40–$56/hr

  • New grads welcomed · reported
  • RN
  • Flexible shifts including mornings, evenings, weekends, and holidays
  • Outpatient Dialysis
CommonSpirit Health logo

CommonSpirit Health

San Luis Obispo, CA

PCU RN

$52–$77/hr

  • RN
Healthforce logo

Healthforce

San Luis Obispo, CA · Staffing partner

Travel Registered Nurse Med Surg Job

Posted last week

$1,929–$2,008/week

  • RN
  • Travel contract
White Glove Placement, Inc. logo

White Glove Placement, Inc.

San Luis Obispo, CA · Staffing partner

  • RN
  • 12-⁠hour rotating
  • Travel contract

Focus Staff

San Luis Obispo, CA · Staffing partner

  • RN
  • 3x12 Nights
  • Travel contract
HealthForce Healthcare logo

HealthForce Healthcare

San Luis Obispo, CA · Staffing partner

  • RN
  • 12-⁠hour nights
  • Travel contract
Hire Evolution Consulting logo

Hire Evolution Consulting

San Luis Obispo, CA · Staffing partner

  • LVN
  • AM 6am - 230pm, PM 2pm - 1030pm or NOC 10pm to 630am
  • Travel contract
AMN Healthcare Nursing logo

AMN Healthcare Nursing

San Luis Obispo, CA · Staffing partner

  • RN
  • 12-⁠hour nights
  • Travel contract

Fusion Medical Staffing

San Luis Obispo, CA · Staffing partner

ICU RN

$1,844–$1,962/week

  • RN
  • Travel contract
  • CEU allowance
TNAA Healthcare logo

TNAA Healthcare

San Luis Obispo, CA · Staffing partner

RN NICU

$1,936/week

  • RN
  • Travel contract
Option Care Health logo

Option Care Health

San Luis Obispo, CA

  • RN
Adventist Health logo

Adventist Health

San Luis Obispo, CA · Health system employer

  • RN/CNA
  • Night shift
Dignity Health logo

Dignity Health

San Luis Obispo, CA

RN

$57–$87/hr

  • RN
Wellpath logo

Wellpath

San Luis Obispo, CA

LVN, Travel

Posted last week

$40–$45/hr

  • LVN
  • 12-⁠hour nights
  • Travel contract
CommonSpirit Health logo

CommonSpirit Health

San Luis Obispo, CA

  • RN
  • Night shift
  • Labor and Delivery Nursing
Healthforce logo

Healthforce

San Luis Obispo, CA · Staffing partner

Travel Registered Nurse ER Job

$2,155–$2,260/week

  • RN
  • 12-⁠hour days
  • Emergency Department
White Glove Placement, Inc. logo

White Glove Placement, Inc.

San Luis Obispo, CA · Staffing partner

  • RN
  • 8-⁠hour rotating
  • Travel contract
HealthForce Healthcare logo

HealthForce Healthcare

San Luis Obispo, CA · Staffing partner

  • RN
  • 10-⁠hour rotating
  • Travel contract
Hire Evolution Consulting logo

Hire Evolution Consulting

San Luis Obispo, CA · Staffing partner

  • LVN
  • 8-⁠hour nights
  • Travel contract
Adventist Health logo

Adventist Health

San Luis Obispo, CA · Health system employer

  • RN/CNA
  • Day shift
CommonSpirit Health logo

CommonSpirit Health

San Luis Obispo, CA

RN

$57–$87/hr

  • RN
HealthForce Healthcare logo

HealthForce Healthcare

San Luis Obispo, CA · Staffing partner

  • RN
  • 8-⁠hour days
  • Travel contract
Adventist Health logo

Adventist Health

San Luis Obispo, CA · Health system employer

  • RN/CNA
  • Day shift
  • Per diem
CommonSpirit Health logo

CommonSpirit Health

San Luis Obispo, CA

  • RN

Adventist Health

6 open roles

RN II - Step Down Unit (CNA), Full Time, Day Shift

San Luis Obispo, CA · Closes Fri

$68/hr

$52–$84/hr

  • RN/CNA
  • Day shift

Certified Nursing Assistant (SEIU), Full Time, Night Shift

San Luis Obispo, CA · Closes Fri

$26/hr

$25–$27/hr

  • CNA
  • Night shift

RN II-ED, Part-Time, Night Shift (CNA)

San Luis Obispo, CA · Posted 4 days ago

$68/hr

$52–$84/hr

  • RN/CNA
  • Night shift

RN II - OR, Full-Time, Rotating Shift (Mandatory call) (CNA)

San Luis Obispo, CA · Posted last week

$68/hr

$52–$84/hr

  • RN/CNA
  • Rotating shift

RN II-MED-SURG (CNA), Part Time, Night Shift

San Luis Obispo, CA · Posted last week

$68/hr

$52–$84/hr

  • RN/CNA
  • Night shift

RN II-L&D (Mandatory Call), Per Diem, Day Shift (CNA)

San Luis Obispo, CA · Closing date passed

$68/hr

$52–$84/hr

  • RN/CNA
  • Day shift
  • Per diem

Working and living in San Luis Obispo

· 95 open roles

Posted hourly pay

RN
$52/hr median
$50–$57/hr middle half · 19 postings

See roles with listed pay

Living costs

Metro price level
108.6 (100 = national)
BEA 2024
Median gross rent
$1,965/mo
Rent and tenant-paid utilities
Median household income
$73,685/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

6 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

9 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • DNP1
  • NP3
  • RN78
  • LPN1
  • LVN6
  • CNA37

One posting may accept more than one credential.

Shifts listed

  • Nights31
  • Days25
  • Rotating12
  • per-diem8

Postings may list several shifts or leave the shift unspecified.

Living in San Luis Obispo

San Luis Obispo is a compact Central Coast college town between volcanic peaks and wine country, halfway from L.A. to San Francisco on Highway 101. Cal Poly keeps the median age near 30 and downtown—Higuera Street, the 1772 Mission, Bubblegum Alley, Scout Coffee, Firestone Grill—alive, especially at Thursday’s Farmers Market.

More about life here

Bishop Peak, Laguna Lake, Montana de Oro, and the Nine Sisters make after-shift hikes realistic; Avila and Pismo are close, if chilly. Edna Valley vineyards start at the city’s edge.

Housing is the shock: median homes near $900,000–$953,000 and one-bedroom rents from the high $1,800s to about $3,000. Downtown is walkable but noisy with tight parking; Laguna Lake and Foothill trade convenience for trails; the East Side plus Arroyo Grande or Pismo (25–30 minutes) stretch a budget further. In-town commutes average about 13 minutes, yet SLO is somewhat isolated, restaurants close early, and locals flag a thinner job market and healthcare challenges.

Weather consoles: about 285 sunny days, August highs near 80°F, winter nights around 50°F.

Sources
As of Sep 11, 2026
Neighborhoods

Downtown San Luis Obispo is the walkable core—restaurants, shops, nightlife, historic homes, and a short hop to Cal Poly—with higher prices, noise, activity, and limited parking. Laguna Lake is a popular suburban residential pocket known for parks, open space, and trail access; it suits people who want nature nearby but accept more driving and weaker walkability to downtown.

Bishop Peak and the Foothill area are quieter, view-oriented neighborhoods of established homes with direct hiking access, limited inventory, and mixed home ages and conditions. SLO’s East Side is framed as family-friendly with more entry-level stock for first-time buyers; the Cal Poly/West University area is campus-adjacent; Los Ranchos/Edna Valley leans toward vineyard acreage and luxury estates (airport/air traffic is a factor on that south side).

Nearby Pismo Beach and Arroyo Grande are the usual “somewhat more affordable” alternatives, about a 25–30 minute commute into SLO.

Sources
Housing

Housing is the budget-breaker. U.S. News lists a median home value of $898,981 and median rent of $1,836; Apartment Guide (2024) cites a median sale price around $953,000 and average rent of $3,000 for a one-bedroom.

Downtown is the premium, walkable tier; the East Side is the usual entry-level/family stock; Foothill and Laguna Lake are established residential; Los Ranchos/Edna Valley is acreage and luxury among vineyards. Pismo Beach and Arroyo Grande are the nearby “somewhat affordable” overflow.

Limited supply, sellers not under pressure, and sticker shock versus most of the country are the market’s personality; within California it can look less extreme than Los Angeles or the Bay Area. Median household income is $78,523, so an $80k–$150k nurse wage sits at or above typical local households while still stretching hard against those home prices.

Sources
Getting around

U.S. News reports an average San Luis Obispo commute of about 13.29 minutes, reflecting a compact city rather than a long suburban grind. Downtown living buys that convenience at the cost of limited parking; Laguna Lake and similar residential areas mean more driving for errands and nightlife.

Relocators commonly live in Pismo Beach or Arroyo Grande and budget 25–30 minutes into SLO. Highway 101 is the county spine; San Luis Obispo’s airport and associated air traffic sit toward Edna Valley.

Sources do not name hospital campuses, transit lines, or shift-parking rules, so expect a car-first pattern outside the downtown core.

Sources
Food and dining

Downtown—especially Higuera Street—is the everyday food district: pedestrian shopping, restaurants, and coffee with college-town energy. Named local stops include Firestone Grill and Giovanni’s for casual meals, Wayward Bakery and Yokoso Coffee, plus student/local cafes Scout Coffee and Kreuzberg California.

Thursday evenings the Downtown SLO Farmers Market takes over with food vendors, produce, live music, and a civic crowd that doubles as a weekly dinner plan. Edna Valley, Arroyo Grande, and Paso Robles add tasting rooms just outside town.

A practical con for hospital shifts: locals say restaurants close early, so true late-night options are thin compared with a larger city.

Sources
Outdoors

Outdoor life is the city’s main amenity: more than 50 parks, volcanic Nine Sisters peaks running toward Morro Bay, and trailheads inside town. Bishop Peak is the signature hike with city views; Laguna Lake offers parks and open space; Montana de Oro State Park and Pismo Preserve are the big coastal hiking days.

Avila Beach and Pismo Beach sit a short drive away (a creek runs from SLO toward Avila); the county markets about 80 miles of beaches. Edna Valley vineyards start at the south edge; elephant seals are a San Simeon outing.

Hiking and mountain biking are year-round in the mild climate.

Sources
Arts and culture

Mission San Luis Obispo de Tolosa, founded in 1772, still holds daily mass; volunteers ring the bells at noon and 6 p.m. Downtown mixes Spanish Colonial and Victorian buildings with Bubblegum Alley, the San Luis Obispo Museum of Art (SLOMA), the Children’s Museum, and the historic Fremont Theater for film and live performance.

Thursday’s Farmers Market is the weekly civic ritual; an emerging arts scene, galleries, and college-town energy fill the rest of the calendar. SLO is the gateway to more than 250 wineries across Edna Valley, Arroyo Grande, and Paso Robles.

Nightlife exists but is not a late-night metropolis. The city has committed to carbon neutrality by 2035 and installed nearly 200 EV charging stations.

Sources
Seasons and weather

The climate is Mediterranean and a primary reason people move here. A local realtor filming in August cited highs around 81°F and December/January lows around 48–50°F; Apartment Guide lists an average summer high of 79°F and about 285 days of sunshine.

It is sunny nearly every day without inland-California heat. Coastal beaches can still feel chilly even when town is pleasant, which is the main seasonal surprise for newcomers used to warm water.

Sources
For families

About 47,000–48,900 people live in the city (metro over 280,000), with a median age of 29.7 pulled down by Cal Poly, so the texture is college-town plus families rather than a retiree enclave. The East Side is explicitly described as family-friendly with more entry-level homes; Laguna Lake is the suburban, parks-and-trails balance.

Downtown has the San Luis Obispo Children’s Museum, the Mission, and Thursday Farmers Market; the city claims more than 50 parks. Sources do not name school districts, ratings, or childcare waitlists, so those need a separate local check.

Sources
What locals say

People describe SLO as charming, temperate, and unusually balanced—a college town that still feels family-friendly and “just right”—and Visit California notes National Geographic and Oprah branded it the happiest city in the country. Reddit and relocators are blunter: it is expensive, somewhat isolated, semi-rural around the edges, with easy nature access and a beautiful but chilly nearby beach.

A Central Coast realtor who grew up in the county flags restaurants that close early, high property prices, thinner job opportunities, and some healthcare-system challenges. Sticker shock versus the rest of the country is common; compared with the LA–Bay Area corridor the same market can feel a bit less extreme, but limited supply and unhurried sellers still make buying slow and selective.

Sources

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