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35 nursing jobs in Sioux City, IA

Anchoring the tri-state Siouxland, Sioux City stretches your nursing paycheck with living costs about 13.5% below the national average. Settle into restored commercial lofts in the Historic Fourth Street District, tree-lined streets near Morningside University, or master-planned Whispering Creek, with easy Missouri River crossings into Nebraska and South Dakota.

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Sunrise Retirement Community — a workplace named in a current Sioux City postingView Sunrise Retirement Community →

Find a nursing job in Sioux City

Hiring here: UnityPoint Health (21) · TNAA Healthcare (2) · Accura HealthCare (1) · Advanced Correctional Healthcare (1) · American Traveler (1) · Daisy Medical Staffing Inc (1)

  • Sign-on bonus
  • RN/LPN
  • 8-⁠hour days

Perdue Farms

Sioux City, IA

  • RN
  • Per diem

Genie Healthcare

Sioux City, IA

Med Surg Registered Nurse

Up to $2,272/week

  • RN
  • 12-⁠hour days
  • Travel contract
UnityPoint Health logo

UnityPoint Health

Sioux City, IA · Health system employer

Anesthesia - CRNA

Closing date passed

  • CRNA
  • Tuition reimbursement
Iowa Total Care logo

Iowa Total Care

Sioux City, IA

Maternity RN Care Manager

$56,000–$101,000/year

  • RN
  • 8-⁠hour days
  • Compact license OK
  • RN
  • Ful Time- Weekend On Call Friday 5PM-Monday 8AM
  • Tuition reimbursement
Accura HealthCare logo

Accura HealthCare

Sioux City, IA

  • LPN
  • 8-⁠hour nights
St. Croix Hospice logo

St. Croix Hospice

Sioux City, IA

  • RN
  • Rotating shift
  • Compact license OK
  • RN
  • Full-Time Nights
Daisy Medical Staffing Inc logo

Daisy Medical Staffing Inc

Sioux City, IA · Staffing partner

  • RN
  • 12-⁠hour rotating
  • Agency contract
TNAA Healthcare logo

TNAA Healthcare

Sioux City, IA · Staffing partner

Telemetry RN

$2,019/week

  • RN
  • Day shift
  • Travel contract
American Traveler logo

American Traveler

Sioux City, IA · Staffing partner

  • RN
  • 7:00 PM to 7:00 AM
  • Travel contract
UnityPoint Health logo

UnityPoint Health

Sioux City, IA · Health system employer

  • CRNA
  • Operating Room / Surgery
  • Tuition reimbursement
TNAA Healthcare logo

TNAA Healthcare

Sioux City, IA · Staffing partner

ICU RN

$2,750/week

  • RN
  • Travel contract

UnityPoint Health

19 open roles

RN Occupational Health

Sioux City, IA · Posted last week

  • RN

RN 5A Medical/Telemetry

Sioux City, IA · Posted last week

  • RN

Registered Nurse 3A Med/Surg Flex

Sioux City, IA · Posted last week

  • RN
  • 7pm-7am (12 hr/shifts and every third weekend) Full-Time
  • Tuition reimbursement
  • RN
  • 12-⁠hour days
  • Tuition reimbursement

RN Emergency

Sioux City, IA

  • New grads welcomed
  • RN
  • 12-⁠hour rotating
  • RN
  • 8-⁠hour days
  • Compact license OK

RN Stepdown

Sioux City, IA

  • New grads welcomed
  • RN
  • 12-⁠hour days

ICU RN

Sioux City, IA

  • RN
  • 12-⁠hour nights
  • Tuition reimbursement

RN Poison Center

Sioux City, IA

  • RN
  • Rotating shift
  • Poison Control Center
  • New grads welcomed · reported
  • RN
  • Monday-Friday 8AM-4:30PM
  • Cardiology - Sunnybrook
  • New grads welcomed · reported
  • RN
  • 8-⁠hour days
  • Compact license OK
  • New grads welcomed · reported
  • RN
  • 7pm-7am (12/hr shifts and every third weekend)
  • RN
  • 8-⁠hour days
  • Tuition reimbursement

RN Medical-Nephrology

Sioux City, IA

  • New grads welcomed
  • RN
  • 12-⁠hour rotating
  • LPN
  • 8-⁠hour days
  • Tuition reimbursement

RN Neuro-Ortho

Sioux City, IA

  • New grads welcomed
  • RN
  • 12-⁠hour rotating
  • RN
  • Per diem
  • Tuition reimbursement

Working and living in Sioux City

· 35 open roles

Living costs

Metro price level
86.5 (100 = national)
BEA 2024
Median gross rent
$976/mo
Rent and tenant-paid utilities
Median household income
$68,906/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

7 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

3 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • CRNA2
  • RN31
  • LPN3

One posting may accept more than one credential.

Shifts listed

  • Days13
  • Nights6
  • Rotating6
  • per-diem2

Postings may list several shifts or leave the shift unspecified.

Living in Sioux City

Perched at the tri-state crossroads of Iowa, Nebraska, and South Dakota, Sioux City offers healthcare workers an easygoing, community-centered base framed by the scenic Loess Hills and the Missouri River.

More about life here

Shift commutes are virtually stress-free, generally clocking in around fifteen minutes whether you live near the leafy campus streets of Morningside, the historic lofts of Fourth Street, or suburban pockets in Whispering Creek and across the border in South Sioux City. Outside hospital shifts, the pace is comfortable and restorative: hike bluffs in Stone State Park, tube or run the loop trail at Cone Park, or catch a USHL Musketeers hockey game downtown.

Dining ranges from legendary loose-meat sandwiches at Tastee Inn and Out to craft drafts and cocktails at The Diving Elk. The primary tradeoff is the biting winter climate, requiring serious cold-weather gear and car preparation, coupled with minimal public transit that makes driving essential.

For clinicians wanting approachable regional living without traffic headaches, Sioux City delivers steady comfort and tri-state versatility.

Sources
As of Sep 16, 2026
Neighborhoods

Residential options in the tri-state Siouxland area span historic city enclaves and newer suburban developments across state lines. The Morningside neighborhood offers established, tree-lined residential streets surrounding Morningside University, while the Historic Fourth Street District provides urban loft living within restored commercial architecture.

Newer single-family housing and planned suburban developments are clustered in areas like Whispering Creek, portions of the north side, and neighboring bedroom communities such as Sergeant Bluff, Iowa, and Dakota Dunes across the South Dakota border. Just across the Missouri River, South Sioux City, Nebraska, serves as another practical, low-stress residential base with older rental buildings alongside newer units.

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Housing

Housing options range from historic conversions to traditional single-family suburban subdivisions. Renters looking for urban character lean toward loft conversions in the Historic Fourth Street District, while more traditional apartment communities are scattered near college campuses like Morningside University and Briar Cliff University, as well as across the river in South Sioux City.

For buyers, established mid-century homes define neighborhoods like Morningside, whereas newer, higher-tier single-family builds are concentrated in master-planned pockets like Whispering Creek and northern suburban corridors.

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Getting around

Sioux City is an exceptionally car-dependent metro where daily travel is quick and uncongested, averaging around fifteen to sixteen minutes across the region. Public transit coverage is minimal, meaning healthcare workers almost universally rely on personal vehicles to reach medical centers and clinics.

Interstate 29 and local river crossings like the Veteran's Memorial Bridge connect communities across Iowa, Nebraska, and South Dakota with minimal friction, making cross-river drives from South Sioux City or Dakota Dunes just a short trip.

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Food and dining

The local dining scene mixes historic regional classics with contemporary gathering spots. Local institutions include Tastee Inn and Out, serving iconic loose-meat sandwiches and onion chips since the 1950s, and El Fredo's for long-standing local pizza tradition.

Morning coffee runs and casual lunches draw people to SweetWater Café, while Palmer's Olde Tyme Candy Shoppe celebrates local confectionery history as the home of the Twin Bing. In the downtown district, gastropubs like The Diving Elk offer craft cocktails and dinner menus, complemented by local breweries and nightlife venues.

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Outdoors

Outdoor recreation is anchored by the unique topography of the Loess Hills and the Missouri River. Stone State Park features extensive hiking trails through native woodlands and bluffs, complemented by interactive exhibits and trailheads at the Dorothy Pecaut Nature Center.

The riverfront offers recreational green space near the Anderson Dance Pavilion, alongside regional networks encompassing roughly seventy miles of trails. In town, Cone Park hosts summer tubing, a splash pad, and a loop trail, while South Sioux City features walking paths and ice fishing at Crystal Cove Lake Park, soccer fields at Jeffrey C. Dible Soccer Complex, and river panoramas at Siouxland Freedom Park.

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Arts and culture

Sioux City's cultural anchor is downtown, where the restored Orpheum Theatre hosts performing arts and concerts, and the Sioux City Art Center presents regional and national exhibits. Heritage is preserved at the Sioux City Public Museum and the Lewis and Clark Interpretive Center along the river.

Sporting culture centers heavily on hockey, with locals gathering to support the USHL Sioux City Musketeers. Religious and architectural sightseeing includes the sixteen-acre Trinity Heights Queen of Peace shrine with its massive outdoor sculptures.

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Seasons and weather

Life in Sioux City brings four pronounced Midwestern seasons. Summers are warm and humid, creating ideal conditions for Missouri River boating, hiking, and park activities.

Winters are bitterly cold, characterized by sub-freezing stretches and heavy snow that make warm winter coats, all-wheel drive, and vehicle remote starters practical necessities. Spring and autumn serve as colorful, pleasant transitional seasons with vivid foliage across the river bluffs.

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For families

The area is well-suited for family living, supported by quiet neighborhoods, community sports hubs, and youth-oriented attractions. Families frequently visit the LaunchPAD Children's Museum downtown and spend weekends at the Jeffrey C. Dible Soccer Complex or the Cone Park splash pad and tubing hill.

The local educational landscape features neighborhood schools such as Sunnyside Elementary, alongside higher education presences like Briar Cliff University and Western Iowa Tech Community College that anchor community programming.

Sources
What locals say

Residents appreciate Sioux City's unpretentious Midwestern warmth, close-knit community feel, and absence of big-city traffic snarls. The ease of getting around and the abundance of open space make daily routines low-stress.

On the flip side, newcomers and locals note that the area lacks the extensive cultural and entertainment breadth of major metropolitan hubs, and the severe, freezing winter conditions demand winter-ready vehicles and remote starters.

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