30 nursing jobs in Anderson, SC
Anderson pairs an easy commute to AnMed Health with a cost of living about 7% below the national average. Settle into quiet neighborhoods like Concord or Highway 81 apartments, spend post-shift afternoons boating Lake Hartwell from Darwin Wright Park, and unwind downtown with dinner on Earle Street or craft pours at Carolina Bauernhaus.
Also hiring: Anderson, IN (36)
Find a nursing job in Anderson
Hiring here: Regency Hospital - Upstate (6) · DAVITA (4) · ACG Hospice (3) · 110 Prisma Health-Upstate (2) · Gentiva Hospice (2) · Regency Hospital Company (2)

Regency Hospital - Upstate
3 open roles
Regency Hospital - Upstate
3 open roles
- RN
- Per diem
- Sign-on bonus
- RN
- 12-hour nights
- Sign-on bonus
- RN
- 12-hour days
1Registered Nurse (RN) Weekend Shift - Home Health
$70,000–$90,000/year
- RN
- Weekend shift
- Compact license OK
Nurse Practitioner/ Physician Assistant, 7 on / 7 off
Up to $150,000/year
- NP
- 12-hour 12 hour
- NP
- Day shift
Registered Nurse (RN) / Days
$40–$53/hr
- Sign-on bonus
- RN
- Full-Time Days, 12-hour shifts
- Tuition reimbursement
Registered Nurse (RN) / Days
$40–$53/hr
- Sign-on bonus
- RN
- Full-Time Days, 12-hour shifts
- Tuition reimbursement
- RN
- Night shift
- Travel contract
Travel RN - Med/Surg Float Pool
$1,746/week
- RN
- Ratio 1:5–1:6
- 18:45-7:15
- New grads welcomed
- LPN
- Day shift
- Compact license OK
Registered Nurse (RN) / Nights
$40–$53/hr
- Sign-on bonus
- RN
- 12-hour nights
- Tuition reimbursement
- Sign-on bonus
- RN
- 12-hour shifts
- Travel contract
Working and living in Anderson
· 30 open roles
Living costs
- Median gross rent
- $975/mo
- Rent and tenant-paid utilities
- Median household income
- $46,933/yr
- All local households, not nurse pay
New to our board this week
2 current postings first appeared here in the past seven days.
Credentials accepted
- NP3
- RN25
- LPN1
- CNA1
One posting may accept more than one credential.
Shifts listed
- Days6
- Nights5
- per-diem5
- Rotating4
- weekend1
Postings may list several shifts or leave the shift unspecified.
Living in Anderson
Known as the 'Electric City,' Anderson is an unpretentious Upstate South Carolina regional hub that offers healthcare professionals an attractive, lower-stress alternative to Greenville.
More about life hereShow less
Working at AnMed Health means easy daily commutes, typically under 20 minutes from established residential neighborhoods like Concord, Cobb's Glen, or apartment communities off Highway 81. Off-duty life balances quiet small-town hospitality with easy access to major recreation: Lake Hartwell sits just minutes west for boating, swimming, and fishing at Darwin Wright Park, while downtown Anderson offers walkable dining at Earle Street and artisanal sips at Carolina Bauernhaus. On weekends, the sprawling Anderson Farmers Market and Carolina Wren Park host community gatherings, with Interstate 85 putting downtown Greenville and Clemson within easy striking distance.
The main tradeoffs are commercial traffic congestion along Clemson Boulevard and a nightlife scene that quiet down early, which may feel slow for younger singles. For nurses seeking affordable space, manageable shifts, and a grounded Southern community, Anderson delivers a practical, well-balanced landing spot.
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Neighborhoods
Healthcare workers and young professionals relocating to Anderson typically focus on a few distinct corridors. For rental apartments, complexes along Highway 81 and Clemson Boulevard north of downtown are widely favored for their quick hospital access and proximity to retail.
Buyers seeking established suburban character gravitate to Concord, Ashley Downs, or the golf-oriented Cobb's Glen, which feature mature trees and manicured yards. Newer master-planned communities include Brookstone Meadows and Plantation Pointe, while lake enthusiasts favor Northlake and the Regatta community along Lake Hartwell.
More modest starter homes can be found in established pockets like Westview Heights and Lakeside.
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Housing
Housing in Anderson provides a range of options that skew noticeably more accessible than neighboring Greenville. Rental apartments are primarily clustered along Highway 81 and Clemson Boulevard north of the core, offering modern layouts with standard amenities.
Single-family home options range from historic properties near downtown to newer planned subdivisions such as Brookstone Meadows. Golf communities like Cobb's Glen offer settled, country-club environments on larger lots, while direct waterfront properties along Lake Hartwell command the highest price tiers in the county.
First-time buyers often target accessible, established neighborhoods like Westview Heights.
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Getting around
Commutes within Anderson are manageable, with typical drives across the city running around 15 to 20 minutes. AnMed Health serves as the city's primary medical anchor, situated conveniently off the Highway 81 corridor where hospital parking is straightforward surface parking.
Clemson Boulevard and North Main Street act as the central north-south retail and commuter arteries, though Clemson Boulevard frequently bottlenecks with strip-mall traffic during peak hours. For those traveling regionally, Interstate 85 provides direct transit, putting Clemson roughly 20 minutes northwest and downtown Greenville about 30 minutes northeast.
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Food and dining
Anderson's culinary landscape blends traditional Southern meat-and-three dining with independent downtown eateries. Downtown features casual craft destinations like Carolina Bauernhaus Brewery & Winery, Palmetto Distillery for small-batch spirits, and handmade confections from CocoBon Chocolatier.
North Main Street offers local institutions such as Mama Penn's for classic home-cooked Southern breakfasts and lunches, alongside refined dinner spots like Earle Street. Clemson Boulevard hosts standard national chains like Texas Roadhouse as well as local favorites including Nami for sushi, while regional dairy and farm goods from Split Creek Farm are staple offerings at the downtown farmers market.
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Outdoors
Lake Hartwell defines outdoor life in the Anderson area, spanning tens of thousands of acres with public beaches, boat ramps, lakeside camping, and renowned bass-fishing tournaments. Darwin Wright Park provides lake access and a public fishing pier right on the water.
In the center of town, Carolina Wren Park offers manicured green space, walking paths, and community gathering areas, while Rocky River Nature Park features protected wetlands and quiet nature trails. The city also maintains over 60 public parks and extensive athletic facilities across the Anderson Sports and Entertainment Center grounds.
Arts and culture
Anderson takes pride in its heritage as the 'Electric City,' celebrating its status as an early pioneer in electric power. The Historic Downtown Anderson district anchors the cultural scene around the Anderson County Courthouse, hosting community festivals, seasonal outdoor ice skating, and the sprawling Anderson Farmers Market.
The Anderson County Museum explores regional history, while the Anderson Sports and Entertainment Center hosts touring concerts and outdoor events. For bargain-hunting and local color, the 65-acre Anderson Jockey Lot serves as an iconic regional open-air market, and painted barn murals form the local Upstate Heritage Quilt Trail.
Seasons and weather
Anderson experiences four distinct seasons shaped by its Upstate Piedmont climate. Summers are long, intensely hot, and humid, with temperatures frequently reaching the upper 80s and 90s, driving locals toward water activities on Lake Hartwell.
Winters are brief and relatively mild, with temperatures rarely dipping below freezing for extended stretches and snow occurring infrequently. Spring and autumn offer the most pleasant weather, marked by vibrant dogwood and azalea blooms in April and rich fall foliage changes across the nearby Blue Ridge foothills by late October.
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For families
Anderson offers an appealing environment for families looking for quiet residential communities and manageable routines. Neighborhoods such as Summerfield Plantation, Sadlers Forest, and Ashley Downs are popular with parents due to their sidewalk-lined streets, mature tree cover, and neighborhood feel.
Indoor activities include family-oriented spots like Big Air trampoline park and Let's Play Pretend, alongside open play at the Civic Center and Carolina Wren Park. Anderson University contributes cultural and sporting events to the area.
While public schools have strong local involvement, residents recommend researching specific attendance zones and focusing home searches north of the downtown core for settled family pockets.
What locals say
Residents describe Anderson as a welcoming, community-driven city that lives up to its 'City of Hospitality' reputation, offering a noticeably calmer pace of life than nearby Greenville. Locals praise the convenience of AnMed Health, easy water recreation on Lake Hartwell, and a growing downtown restaurant scene.
However, community reviews also point out real drawbacks: Clemson Boulevard experiences frustrating suburban sprawl, entertainment and nightlife options for young singles remain sparse, and some long-term social circles can feel insular. Drivers are frequently critiqued, and residents note that certain neighborhoods experience higher property crime rates.