56 nursing jobs in Carlisle, PA
Anchored in the Cumberland Valley, Carlisle pairs brick-lined downtown streets and Dickinson College charm with shifts at UPMC Carlisle. Between rounds, hike the nearby Appalachian Trail or browse spots along High Street. Best of all, living costs sit about 1% below the national average, letting your nursing paycheck stretch further in central Pennsylvania.
Find a nursing job in Carlisle
Hiring here: UPMC (34) · Claremont Nursing & Rehabilitation Center (6) · Adoration Health (2) · PrimeCare Medical, Inc. (2) · Chapel Pointe at Carlisle (1) · Claremont Nursing & Rehabilitation Center (1)
- Sign-on bonus
- RN
- 8-hour nights
- Tuition reimbursement

Claremont Nursing & Rehabilitation Center
3 open roles · weekend & evening shifts · Permanent
Claremont Nursing & Rehabilitation Center
3 open roles · weekend & evening shifts · Permanent
- LPN
- Weekend shift
Registered Nurse Weekdays Supervisor 3 to 11
Carlisle, PA
- RN
- Evening shift
RN Charge Nurse
Carlisle, PA
- RN
- 8-hour evenings
- ADN accepted
Weekend Registered Nurse (RN)
$55–$60/hr
- New grads welcomed · reported
- RN
- Weekend shift
Home Health LPN
$25–$30/hr
- LPN
- Tuition reimbursement
- Sign-on bonus
- LPN
- Monday - Friday 8:30a-8:00p Saturday - Sunday 7:30a-6:00p
- Carlisle Urgent Care
Licensed Practical Nurse
$30–$36/hr
- LPN
- 12-hour nights
- Tuition reimbursement
CRNA, UPMC Carlisle
$280k–$405
t us provide you with a life-changing career, including student loan forgiveness, a salary range of $280k - $405+k, an employer-funded retirement plan and up to $125k sign-.
- New grads welcomed
- CRNA
- Tuition reimbursement
- RN
- Schedule: M-F 8a to 5p
- Tuition reimbursement
- RN
- Travel contract
Claremont Nursing & Rehabilitation Center
Carlisle, PA
Registered Nurse Supervisor 11 to 7
$50–$55/hr
- RN
- 11am to 7pm
- RN
- M-F 8a to 5p
- Tuition reimbursement
UPMC
24 open roles
UPMC
24 open roles
- New grads welcomed
- RN
- Our RNs work a variety of shifts to ensure 24/7 coverage on the floor.
Sr. Professional Staff Nurse, Casual - L&D (Carlisle)
Carlisle, PA · Posted today
Professional Staff Nurse - NICU (Carlisle)
Carlisle, PA · Posted today
- Rotating shift
Professional Staff Nurse, Casual - L&D (Carlisle)
Carlisle, PA · Posted today
Professional Staff Nurse - L&D (Carlisle)
Carlisle, PA · Posted today
- Rotating shift
Nursing Assistant - Inpatient Rehab - Carlisle
Carlisle, PA · Posted last week
- New grads welcomed
- Rotating shift
- Compact license OK
- Sign-on bonus
- Compact license OK
- New grads welcomed
- Sign-on bonus
- RN
- Rotating shift
- Compact license OK
- New grads welcomed
- RN
- Rotating shift
- Compact license OK
Graduate Nurse Dec 2026 Grads - UPMC Carlisle
Carlisle, PA
- New grads welcomed
- RN
- Our RNs work a variety of shifts to ensure 24/7 coverage on the floor.
- Compact license OK
- RN
- Rotating shift
- Per diem
- RN
- Night shift
- Compact license OK
- Sign-on bonus
- RN
- 12-hour nights
- Acute Cardiac & Neuro Unit
- RN
- Rotating shift
- Per diem
- Sign-on bonus
- RN
- 12-hour nights
- Compact license OK
- Compact license OK
- Sign-on bonus
- Rotating shift
- Compact license OK
- Sign-on bonus
- RN
- 12-hour nights
- Compact license OK
- Rotating shift
- Compact license OK
- Sign-on bonus
- RN
- 12-hour nights
- Compact license OK
- New grads welcomed
- RN
- Rotating shift
- Compact license OK
Professional Staff Nurse - ICU (Carlisle)
Carlisle, PA
- New grads welcomed
- Rotating shift
- Compact license OK
Working and living in Carlisle
· 56 open roles
Living costs
- Median gross rent
- $1,094/mo
- Rent and tenant-paid utilities
- Median household income
- $61,720/yr
- All local households, not nurse pay
New to our board this week
7 current postings first appeared here in the past seven days.
Credentials accepted
- CRNA1
- RN28
- LPN9
One posting may accept more than one credential.
Shifts listed
- Rotating17
- Days9
- Nights8
- Evenings4
- per-diem4
- weekend3
Postings may list several shifts or leave the shift unspecified.
Living in Carlisle
Carlisle presents healthcare professionals with an appealing balance of collegiate energy, historical weight, and accessible Cumberland Valley nature.
More about life hereShow less
Home to Dickinson College and the U.S. Army Heritage and Education Center, the borough combines a walkable historic center with leafy, quiet residential areas like the Carlisle West Side and Schlusser Village. When stepping off a shift, clinicians can explore independent local spots on Pomfret Street, grab dinner at Momma Spriggs or Miseno's Ristopub II, or unwind with outdoor activities along the Cumberland Valley Rail Trail, Yellow Breeches Creek, and the nearby Appalachian Trail.
Transportation is practical via Interstates 81 and 76, though nurses commuting across county lines must navigate heavy freight traffic generated by regional distribution centers and ongoing roadway construction. For practitioners seeking an authentic small-town community with robust local dining, historic character, and immediate outdoor recreation, Carlisle remains a compelling central Pennsylvania hub.
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Neighborhoods
Carlisle offers a mix of historic urban streets and quiet suburban pockets. The Historic District and Downtown core surround Dickinson College, attracting those who favor historic brick architecture, local shops, and high walkability.
Just west, the Carlisle West Side (encompassing West Ridge and West Pennsboro) is favored for its quiet residential streets, green space, and quick downtown access. Outlying neighborhoods like Schlusser Village, Kendor Summit, Johnathen Park, and Meeting House Spring Road offer tree-lined suburban layouts, neighborhood parks, and creek access.
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Housing
Housing options range from historic single-family brick homes, townhouses, and divided student-adjacent rentals near downtown and Dickinson College to mid-century ranches and newer suburban subdivisions in West Ridge and peripheral townships. Manufactured home communities such as Western Village and Carlwynne Manor provide entry-level alternatives, while established residential enclaves feature mature trees and larger lot footprints.
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Getting around
Commuting in and out of Carlisle centers heavily on Interstate 81 and Interstate 76 (the Pennsylvania Turnpike), which connect local healthcare workers to regional hospitals and clinics across Cumberland County and Harrisburg. Within the borough, surface streets are walkable and straightforward, but drivers frequently encounter delays caused by high freight volume, regional warehouse trucking, and recurring road construction along primary corridors.
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Food and dining
Carlisle features a vibrant, independent dining scene concentrated around downtown and quirky Pomfret Street. Local staples include Momma Spriggs, The Chop, 113 Social, and Miseno's Ristopub II for relaxed Italian fare, alongside casual bites at The Grazery and Issei.
Beverage and specialty highlights include ciders at Grand Illusion, nostalgia sweets at Georgie Lou's, and regional provisions gathered at the Wednesday Farmers on the Square.
Outdoors
Outdoor enthusiasts benefit from extensive regional trail and water networks throughout the Cumberland Valley. The Appalachian Trail passes nearby, marking its midpoint at Pine Grove Furnace State Park, while the 13-mile Cumberland Valley Rail Trail and trails at Kings Gap Environmental Education Center offer extensive hiking and panoramic vistas.
Water activities include world-class fly fishing and paddling on Yellow Breeches Creek, strolls along Letort Spring Run and LeTort Park, and paddle boating at Children's Lake in Boiling Springs.
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Arts and culture
Carlisle boasts deep heritage dating to the Revolutionary War, highlighted by the historic Carlisle Barracks, the U.S. Army Heritage and Education Center with its Army Heritage Trail, and the Cumberland County Historical Society Museum. The town draws large visitor crowds for the nationally recognized Carlisle Events Car Shows at the fairgrounds, community gatherings like Carlisle Summerfair and Ice Fest, and browsing through multi-story vintage collections at the Carlisle Antique Mall.
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Seasons and weather
Carlisle experiences all four seasons, bringing warm, lively summers ideal for car shows and rail-trail cycling, alongside vibrant foliage across South Mountain in the fall. Winters bring cold temperatures, occasional snowfall, and stretches of cloudy, overcast weather that can make driving conditions unpredictable on local mountain passes and turnpikes.
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For families
Family life in Carlisle is supported by peaceful neighborhoods such as Schlusser Village, Johnathen Park, and the West Side, which offer low-traffic residential streets and proximity to local playgrounds. Families benefit from a strong educational footprint anchored by Carlisle Area public schools, Dickinson College, and nearby Shippensburg University, though parents note that broader commercial entertainment often requires day trips to nearby metro areas.
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What locals say
Locals praise Carlisle for its historic character, small-town friendliness, thriving local restaurant scene, and direct proximity to trails and state parks. The primary frustrations voiced by community members center on heavy semi-truck congestion from the booming regional logistics and warehousing industry, worn roadways under constant repair, periods of overcast weather, and limited large-scale commercial entertainment within town limits.