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23 nursing jobs in Greenwood, SC

Greenwood rests in South Carolina's Lakelands region along the shores of Lake Greenwood. This small city blends Southern small-town ease with lakefront recreation, offering nurses a quieter pace and community feel without big-city demands.

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Wesley Commons workplace
Wesley Commons — a workplace named in a current Greenwood postingView Wesley Commons →

Find a nursing job in Greenwood

Hiring here: Self Regional Healthcare (10) · ACG Hospice (2) · Voyage Health (2) · ATC Healthcare Services of Georgia (1) · American Traveler (1) · Ernest Health (1)

Wesley Commons logo

Wesley Commons

Greenwood, SC

  • RN
  • 12-⁠hour nights
1 / 2

Staff Nurse, ICU, Full Time, Day Shift

Self Regional Healthcare logoSelf Regional Healthcare

Greenwood, SC · Posted 4 days ago

  • RN
1 / 3
  • NP
Self Regional Healthcare logo

Self Regional Healthcare

Greenwood, SC

  • RN
  • Day Shift (7am-7:30pm)
Self Regional Healthcare logo

Self Regional Healthcare

Greenwood, SC

  • RN
  • 1st Shift, 7am-3:30pm, Monday-Friday with call and holiday rotation

Healthcare employer

Greenwood, SC

  • LPN

The Family Hospice

Greenwood, SC

  • RN
WhiteCap Search logo

WhiteCap Search

Greenwood, SC

RN - PCU

Posted 3 days ago

  • RN
Self Regional Healthcare logo

Self Regional Healthcare

Greenwood, SC

  • New grads welcomed
  • RN
Ernest Health logo

Ernest Health

Greenwood, SC · Health system employer

  • LPN
  • 2:00pm to 10:30pm
ACG Hospice logo

ACG Hospice

Greenwood, SC

  • RN
  • Compact license OK
  • Tuition reimbursement
Southern Health Partners logo

Southern Health Partners

Greenwood, SC

  • RN
  • Per diem
  • Tuition reimbursement
ATC Healthcare Services of Georgia logo

ATC Healthcare Services of Georgia

Greenwood, SC · Staffing partner

  • RN
  • 8-⁠hour days
  • Travel contract
Voyage Health logo

Voyage Health

Greenwood, SC · Staffing partner

Travel RN Cath Lab

$2,398–$2,525/week

  • RN
  • 8-⁠hour days
  • Travel contract
American Traveler logo

American Traveler

Greenwood, SC · Staffing partner

Travel RN - ICU

$2,023/week

  • RN
  • 12-⁠hour nights
  • Travel contract
Self Regional Healthcare logo

Self Regional Healthcare

Greenwood, SC

  • RN
  • 12-⁠hour days
  • ADN accepted
ACG Hospice logo

ACG Hospice

Greenwood, SC

  • RN
  • Tuition reimbursement
Voyage Health logo

Voyage Health

Greenwood, SC · Staffing partner

Travel RN Emergency Room

$1,822–$1,918/week

  • RN
  • 12-⁠hour nights
  • Travel contract

Self Regional Healthcare

5 open roles · day & night shifts · Hospital

  • RN
  • 12-⁠hour days
  • ADN accepted
  • RN
  • Day shift
  • ADN accepted

Registered Nurse

Greenwood, SC

$51/hr

  • RN
  • 12-⁠hour nights
  • Travel contract
  • RN
  • 12-⁠hour days
  • ADN accepted

Working and living in Greenwood

· 23 open roles

Open to new grads

1 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

3 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • NP1
  • RN20
  • LPN2

One posting may accept more than one credential.

Shifts listed

  • Days9
  • Nights4
  • Evenings1
  • per-diem1

Postings may list several shifts or leave the shift unspecified.

Living in Greenwood

Greenwood serves as the healthcare and institutional core of South Carolina's Lakelands region, anchored by major employers like Self Regional Healthcare and the Greenwood Genetic Center.

More about life here

For relocating nurses, the town offers a manageable daily commute and a tight-knit community feel without urban traffic. Life outside work often revolves around Lake Greenwood's 11,400 acres of open water, where communities like Puckett's Ferry and Ashton Park offer lakefront living, while inland subdivisions like Gatewood provide traditional suburban comfort.

Uptown Greenwood brings character to off-duty hours with independent eateries, dock-and-dine spots like Break on the Lake, and cultural institutions like the Greenwood Community Theatre and the landmark South Carolina Festival of Flowers. Relocating healthcare professionals must balance these small-town amenities with genuine tradeoffs: public transit is nonexistent, nightlife and upscale retail are limited, and regional travel to cities like Greenville or Columbia requires highway driving due to the absence of a direct interstate.

Nonetheless, those seeking scenic waterside recreation and a quiet pace will find a grounded home base.

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As of Sep 16, 2026
Neighborhoods

Nurses and professionals in Greenwood typically choose between suburban subdivisions close to town and residential communities along the water. Inland, Gatewood offers a quiet suburban setting with family-friendly homes, while Hunters Creek is an established development centered around a golf course featuring larger properties.

Those desiring water recreation gravitate toward Lake Greenwood developments, including Puckett's Ferry, Stonewood, and Ashton Park, which provide direct lake access and scenic waterfront views.

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Housing

The local housing stock includes both rental apartments and detached single-family homes. Apartment complexes in town range from standard rental units to amenity-rich communities suitable for healthcare workers on shift work.

Waterfront enclaves around Lake Greenwood command a premium for scenic vistas and dock access, whereas subdivisions such as Gatewood and Hunters Creek offer traditional single-family neighborhood layouts.

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Getting around

Day-to-day driving within Greenwood is straightforward, with medical staff experiencing short commutes to Self Regional Healthcare and the Greenwood Genetic Center along primary city thoroughfares. Public transportation options are minimal, making a personal vehicle a necessity for commuting and running errands.

Regional connectivity requires navigating two-lane highways and state routes, as the city lacks a direct interstate highway connection, putting Greenville, Columbia, and Augusta roughly an hour or more away by car.

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Food and dining

Local dining clusters around Uptown Greenwood and the Lake Greenwood waterfront. Uptown features independent eateries, casual dining, and local gathering spots, while waterfront venues like Break on the Lake offer outdoor dockside dining where patrons can arrive by boat.

Regional Southern comfort food is a staple throughout local restaurants, highlighted by classic meat-and-vegetable lunch plates and hamburger steak.

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Outdoors

Outdoor life centers largely on Lake Greenwood, an 11,400-acre reservoir offering year-round boating, fishing, and watersports, complemented by public facilities at Lake Greenwood State Park. On land, Greenwood County Park and the nearby Ninety Six National Historic Site provide scenic nature trails and historic walking routes.

For broader regional recreation, the Blue Ridge mountains and Carolina coastline sit within half-day and full-day driving distance.

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Arts and culture

Cultural life is centered in Uptown Greenwood's cultural district, anchored by the Arts Center at the historic Federal Building, the Greenwood Community Theatre, and The Greenwood Museum. The city hosts major regional gatherings that draw tens of thousands of visitors, most notably the South Carolina Festival of Flowers in June and the South Carolina Festival of Discovery in July.

Educational and heritage sites such as the Dr. Benjamin E. Mays Historic Preservation Site round out the local calendar.

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Seasons and weather

Greenwood experiences a warm Piedmont climate highlighted by long, hot summers that drive residents to Lake Greenwood and outdoor festivals in June and July. The surrounding Old 96 District enjoys mild shoulder seasons that accommodate boating, golf, and park visits for much of the calendar year.

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For families

Families relocating to the area often look to residential neighborhoods like Gatewood, Stonewood, and Ashton Park for neighborhood lake access and suburban streets. Public primary and secondary education is administered by Greenwood County School Districts 50, 51, and 52, with higher education offered locally through Lander University and Piedmont Technical College.

Resident perceptions regarding school quality and community safety are mixed, prompting many parents to evaluate specific neighborhood pockets closely.

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What locals say

Residents describe Greenwood as a close-knit, slower-paced Southern community where neighbors know one another and outdoor recreation is right at the doorstep. Supporters highlight the small-town feel, college presence from Lander University, and easy access to lake activities.

Conversely, community critiques frequently focus on elevated crime rates relative to the town's size, a perceived shortage of social and nightlife activities for young professionals, and frustration over the lack of a major interstate running through the county.

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