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68 nursing jobs in Greer, SC

Positioned between Greenville and Spartanburg along I-85 and Wade Hampton Boulevard, Greer puts Upstate medical centers within easy reach. Off shift, stroll brick-paved Trade Street in Historic Greer Station or paddle 800-acre Lake Robinson. With living costs about 7% below the national average, it is an accessible, strategically connected home base.

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Prisma Health workplace
Prisma Health — a workplace named in a current Greer postingView Prisma Health →

Find a nursing job in Greer

Hiring here: 110 Prisma Health-Upstate (30) · Prisma Health (19) · 121 Prisma Health-University Medical Group (10) · The Carolina Center For Behavioral Health (4) · BrightStar Care of Greenville/Spartanburg (1) · Chandler Creek Post Acute (1)

Prisma Health logo

Prisma Health

Greer, SC

  • New grads welcomed
  • RN
1 / 2

Registered Nurse - Full Time 7:00pm-7:30am

The Carolina Center For Behavioral Health

Greer, SC · Posted last week

  • Sign-on bonus
  • RN
  • New grads welcomed
Prisma Health workplace

Prisma Health

12 open roles

BrightStar Care of Greenville/Spartanburg

Greer, SC

  • RN
  • Day shift
  • Per diem

Chandler Creek Post Acute

Greer, SC

  • RN
  • Night shift
  • Per diem

Wren Hospice

Greer, SC

  • RN
  • Rotating shift

The Carolina Center For Behavioral Health

Greer, SC

  • New grads welcomed
  • LPN
  • Compact license OK

121 Prisma Health-University Medical Group

Greer, SC

  • New grads welcomed
  • RN
Prisma Health logo

Prisma Health

Greer, SC

  • RN
  • Variable
  • Compact license OK

110 Prisma Health-Upstate

Greer, SC

  • RN
  • Per diem
Spartanburg Regional Healthcare System logo

Spartanburg Regional Healthcare System

Greer, SC · Health system employer

  • RN
Novant Health logo

Novant Health

Greer, SC · Health system employer

  • RN

The Carolina Center For Behavioral Health

Greer, SC

  • Sign-on bonus
  • RN
  • 12-⁠hour nights
  • Compact license OK

121 Prisma Health-University Medical Group

Greer, SC

  • New grads welcomed
  • LPN

110 Prisma Health-Upstate

Greer, SC

  • RN

The Carolina Center For Behavioral Health

Greer, SC

  • New grads welcomed
  • RN
  • 12-⁠hour days
  • Compact license OK

121 Prisma Health-University Medical Group

Greer, SC

  • RN

110 Prisma Health-Upstate

Greer, SC

  • RN

121 Prisma Health-University Medical Group

Greer, SC

  • NP

110 Prisma Health-Upstate

Greer, SC

  • RN
  • Residency program

121 Prisma Health-University Medical Group

Greer, SC

  • NP

110 Prisma Health-Upstate

Greer, SC

  • RN
  • Per diem

121 Prisma Health-University Medical Group

Greer, SC

  • New grads welcomed
  • RN

110 Prisma Health-Upstate

Greer, SC

  • RN
  • Residency program

121 Prisma Health-University Medical Group

Greer, SC

  • NP

110 Prisma Health-Upstate

Greer, SC

  • RN

121 Prisma Health-University Medical Group

Greer, SC

  • RN

110 Prisma Health-Upstate

Greer, SC

  • New grads welcomed
  • RN
  • Per diem

121 Prisma Health-University Medical Group

Greer, SC

  • NP

110 Prisma Health-Upstate

Greer, SC

  • RN

121 Prisma Health-University Medical Group

Greer, SC

  • NP

110 Prisma Health-Upstate

5 open roles · Permanent

Working and living in Greer

· 68 open roles

Living costs

Metro price level
93.3 (100 = national)
BEA 2024
Median gross rent
$1,198/mo
Rent and tenant-paid utilities
Median household income
$82,626/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

13 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

42 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • NP5
  • RN56
  • LPN7

One posting may accept more than one credential.

Shifts listed

  • Nights10
  • Days8
  • Rotating3

Postings may list several shifts or leave the shift unspecified.

Living in Greer

Greer offers healthcare professionals a strategic foothold in Upstate South Carolina, situated directly between Greenville and Spartanburg along Interstate 85 and Highway 29 (Wade Hampton Boulevard).

More about life here

For nurses commuting to regional medical facilities or Greenville-Spartanburg International Airport, the location balances suburban ease with direct highway access. The city's cultural and social centerpiece is Historic Greer Station, where brick-paved Trade Street hosts boutique shops, independent cafes, and historic architecture, bordered by the 12-acre Greer City Park and its amphitheater.

Residential settings range from established enclaves like Sugar Creek and master-planned subdivisions to rural properties north toward Lake Robinson, an 800-acre retreat popular for paddleboarding and kayaking. However, Greer's rapid growth presents tangible tradeoffs: Wade Hampton Boulevard and I-85 corridors endure notable peak-hour traffic, and life outside downtown is decidedly car-dependent.

Furthermore, the municipal boundary straddles Greenville and Spartanburg counties, requiring newcomers to navigate differences in school zoning and administrative services. For clinicians seeking a welcoming, community-oriented base with easy reach to major Upstate employment centers, Greer delivers practical convenience alongside genuine small-town charm.

Sources
As of Sep 16, 2026
Neighborhoods

Greer offers varied neighborhood settings shaped by its geography across Greenville and Spartanburg counties. Near the core, Historic Greer Station features walkable residential pockets with historic homes and brick-lined streets, while the southern section along Pelham Road (ZIP code 29650) provides convenient proximity to Greenville amenities, commercial corridors, and executive-style communities.

Established subdivisions such as Sugar Creek are popular with families for their community amenities, including multiple neighborhood pools, while the northern reaches (ZIP code 29651) feature larger residential lots, new-construction subdivisions, and a more rural backdrop approaching the Blue Ridge foothills.

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Housing

Housing choices in Greer range from historic single-family residences near downtown to mid-century ranches and sprawling newer subdivisions with homeowners associations. Walkable properties close to Historic Greer Station carry a location premium, while renters frequently look to managed rental communities and apartment complexes clustered near Pelham Road, Highway 29, and major employment zones.

Buyers seeking parcels larger than a quarter-acre generally search northern rural sections, though newcomers must note whether a parcel sits in Greenville or Spartanburg County due to differences in property tax rates and administration.

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Getting around

Greer sits strategically between Greenville and Spartanburg along Interstate 85 and Highway 29 (Wade Hampton Boulevard). Commuters reach downtown Greenville in roughly twenty-five minutes over a twelve-mile drive via Wade Hampton Boulevard, while Spartanburg is approximately seventeen miles east, taking about thirty minutes along I-85. Greenville-Spartanburg International Airport (GSP) is located right on the municipal border, typically reachable in under fifteen minutes.

Daily transit relies almost entirely on personal vehicles, and peak-hour congestion along Wade Hampton Boulevard and the I-85 corridor is a frequent challenge for shift workers.

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Food and dining

Historic Greer Station along Trade Street anchors the local dining scene with independent cafes, award-winning restaurants, bakeries, and coffee shops set in restored commercial buildings. Community food events, such as regular food truck gatherings at Greer City Park and the seasonal Greer Farmers Market, offer casual outdoor dining options, while broader regional culinary destinations in downtown Greenville remain accessible within a short highway drive.

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Outdoors

Greer provides convenient access to manicured public parks and regional lakes. Downtown's twelve-acre Greer City Park features paved walking paths, an amphitheater, and a central water fountain, while Century Park houses an 18-hole disc golf course and exercise stations.

For water recreation, the 800-acre Lake Robinson offers scenic views toward the Blue Ridge foothills and operates under a ten-horsepower boat motor limit, preserving calm conditions for paddleboarding, kayaking, and fishing.

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Arts and culture

Local culture blends historic preservation with industrial heritage. Greer Station includes more than forty buildings listed on the National Register of Historic Places, brick-paved walkways, local boutiques, and an escape room, alongside local history exhibits at the Greer Heritage Museum housed in a 1935 post office.

The city hosts signature community gatherings such as Freedom Blast, Greer Goes Global, and live concerts at the Greer City Park amphitheater, while the nearby BMW Performance Center adds a distinctive automotive connection.

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For families

Greer maintains a family-friendly reputation anchored by highly rated public schools, dedicated parks, and active neighborhood associations. Century Park's sprawling Kids Planet playground is a regional gathering spot for children, and established neighborhoods like Sugar Creek organize community events around shared swimming facilities.

Because Greer spans the border of Greenville County and Spartanburg County, families relocating to the area must carefully verify school zoning and district boundaries when selecting a home.

Sources
What locals say

Residents praise Greer for its welcoming small-town atmosphere, vibrant and revitalized downtown district, and convenient central position between Greenville and Spartanburg employment hubs. However, community discussions regularly cite growing pains fueled by rapid Upstate development, noting rising housing demand, increasing suburban sprawl that mandates driving for almost every errand outside downtown, and aggravating rush-hour traffic along major corridors like Wade Hampton Boulevard.

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