68 nursing jobs in Greer, SC
Positioned between Greenville and Spartanburg along I-85 and Wade Hampton Boulevard, Greer puts Upstate medical centers within easy reach. Off shift, stroll brick-paved Trade Street in Historic Greer Station or paddle 800-acre Lake Robinson. With living costs about 7% below the national average, it is an accessible, strategically connected home base.
Find a nursing job in Greer
Hiring here: 110 Prisma Health-Upstate (30) · Prisma Health (19) · 121 Prisma Health-University Medical Group (10) · The Carolina Center For Behavioral Health (4) · BrightStar Care of Greenville/Spartanburg (1) · Chandler Creek Post Acute (1)
Registered Nurse (RN) - Ambulatory Care, Psychiatry Greer, FT, Days
Posted 2 days ago
- New grads welcomed
- RN
Registered Nurse - Full Time 7:00pm-7:30am
Greer, SC · Posted last week
- Sign-on bonus
- RN
- New grads welcomed

Prisma Health
12 open roles
Prisma Health
12 open roles
Licensed Practical Nurse (LPN) Acute Care, Greer/Patewood Facility Resource Pool, PT, Nights
Greer, SC
- LPN
- Night shift
- Floating required
- New grads welcomed
- RN
- New grads welcomed
- RN
- RN
- Night shift
- RN
- Night shift
- Per diem
- RN
- Night shift
- RN
- Day shift
- Per diem
- RN
- Night shift
- Compact license OK
- RN
- Day shift
- Per diem
- New grads welcomed · reported
- RN
- Night shift
- Compact license OK
- RN
- Rotating shift
- Per diem
- RN
- Day shift
- Compact license OK
- RN
- Day shift
- Per diem
- New grads welcomed
- LPN
- Compact license OK
Registered Nurse (RN) - Ambulatory Care, Psychiatry Greer, FT, Days
Posted 3 days ago
- New grads welcomed
- RN
- RN
- Variable
- Compact license OK
Registered Nurse (RN) - HeartLife, Cardiac\Pulmonary Rehab, PRN, Day
Posted 2 days ago
- RN
- Per diem
- RN
- Sign-on bonus
- RN
- 12-hour nights
- Compact license OK
- New grads welcomed
- LPN
- RN
- Night shift
- Per diem
Registered Nurse (RN) Outpatient, Pre-Assessment, FT, Days
Posted 2 days ago
- RN
- New grads welcomed
- RN
- 12-hour days
- Compact license OK
- RN
- RN
Nurse Practitioner / Physician Assistant - ENT - Greer
Posted 2 days ago
- NP
- RN
- Residency program
- NP
Registered Nurse (RN) Acute Care, Med/Surg, PRN, Days
Posted 2 days ago
- RN
- Per diem
- New grads welcomed
- RN
- RN
- Residency program
Nurse Practitioner / Physician Assistant - ENT - Greer
Posted 2 days ago
- NP
Registered Nurse (RN) Acute Care, Labor and Delivery, PT, Nights
Posted 2 days ago
- RN
- RN
Student Nurse Tech, Medical/Surgical Nursing, PRN, Variable
Posted 2 days ago
- New grads welcomed
- RN
- Per diem
- NP
- RN
- NP
110 Prisma Health-Upstate
5 open roles · Permanent
110 Prisma Health-Upstate
5 open roles · Permanent
Registered Nurse RN) Acute Care, Medical Intensive Care, PT, Nights
Greer, SC · Posted 2 days ago
- RN
Registered Nurse (RN)- Nurse Resident, Winter 2027, Medical/Surgical Unit
Greer, SC · Posted 2 days ago
- RN
- Residency program
Registered Nurse (RN) - Nurse Resident, Winter 2027, Medical Telemetry
Greer, SC · Posted 2 days ago
- RN
- Residency program
Registered Nurse (RN) Acute Care, Emergency Department, PT, Nights
Greer, SC · Posted 2 days ago
- RN
Licensed Practical Nurse (LPN) Acute Care, Med/Surg, FT, Nights
Greer, SC · Posted 2 days ago
- LPN
Working and living in Greer
· 68 open roles
Living costs
- Median gross rent
- $1,198/mo
- Rent and tenant-paid utilities
- Median household income
- $82,626/yr
- All local households, not nurse pay
New to our board this week
42 current postings first appeared here in the past seven days.
Credentials accepted
- NP5
- RN56
- LPN7
One posting may accept more than one credential.
Shifts listed
- Nights10
- Days8
- Rotating3
Postings may list several shifts or leave the shift unspecified.
Living in Greer
Greer offers healthcare professionals a strategic foothold in Upstate South Carolina, situated directly between Greenville and Spartanburg along Interstate 85 and Highway 29 (Wade Hampton Boulevard).
More about life hereShow less
For nurses commuting to regional medical facilities or Greenville-Spartanburg International Airport, the location balances suburban ease with direct highway access. The city's cultural and social centerpiece is Historic Greer Station, where brick-paved Trade Street hosts boutique shops, independent cafes, and historic architecture, bordered by the 12-acre Greer City Park and its amphitheater.
Residential settings range from established enclaves like Sugar Creek and master-planned subdivisions to rural properties north toward Lake Robinson, an 800-acre retreat popular for paddleboarding and kayaking. However, Greer's rapid growth presents tangible tradeoffs: Wade Hampton Boulevard and I-85 corridors endure notable peak-hour traffic, and life outside downtown is decidedly car-dependent.
Furthermore, the municipal boundary straddles Greenville and Spartanburg counties, requiring newcomers to navigate differences in school zoning and administrative services. For clinicians seeking a welcoming, community-oriented base with easy reach to major Upstate employment centers, Greer delivers practical convenience alongside genuine small-town charm.
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Neighborhoods
Greer offers varied neighborhood settings shaped by its geography across Greenville and Spartanburg counties. Near the core, Historic Greer Station features walkable residential pockets with historic homes and brick-lined streets, while the southern section along Pelham Road (ZIP code 29650) provides convenient proximity to Greenville amenities, commercial corridors, and executive-style communities.
Established subdivisions such as Sugar Creek are popular with families for their community amenities, including multiple neighborhood pools, while the northern reaches (ZIP code 29651) feature larger residential lots, new-construction subdivisions, and a more rural backdrop approaching the Blue Ridge foothills.
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Housing
Housing choices in Greer range from historic single-family residences near downtown to mid-century ranches and sprawling newer subdivisions with homeowners associations. Walkable properties close to Historic Greer Station carry a location premium, while renters frequently look to managed rental communities and apartment complexes clustered near Pelham Road, Highway 29, and major employment zones.
Buyers seeking parcels larger than a quarter-acre generally search northern rural sections, though newcomers must note whether a parcel sits in Greenville or Spartanburg County due to differences in property tax rates and administration.
Getting around
Greer sits strategically between Greenville and Spartanburg along Interstate 85 and Highway 29 (Wade Hampton Boulevard). Commuters reach downtown Greenville in roughly twenty-five minutes over a twelve-mile drive via Wade Hampton Boulevard, while Spartanburg is approximately seventeen miles east, taking about thirty minutes along I-85. Greenville-Spartanburg International Airport (GSP) is located right on the municipal border, typically reachable in under fifteen minutes.
Daily transit relies almost entirely on personal vehicles, and peak-hour congestion along Wade Hampton Boulevard and the I-85 corridor is a frequent challenge for shift workers.
Food and dining
Historic Greer Station along Trade Street anchors the local dining scene with independent cafes, award-winning restaurants, bakeries, and coffee shops set in restored commercial buildings. Community food events, such as regular food truck gatherings at Greer City Park and the seasonal Greer Farmers Market, offer casual outdoor dining options, while broader regional culinary destinations in downtown Greenville remain accessible within a short highway drive.
Outdoors
Greer provides convenient access to manicured public parks and regional lakes. Downtown's twelve-acre Greer City Park features paved walking paths, an amphitheater, and a central water fountain, while Century Park houses an 18-hole disc golf course and exercise stations.
For water recreation, the 800-acre Lake Robinson offers scenic views toward the Blue Ridge foothills and operates under a ten-horsepower boat motor limit, preserving calm conditions for paddleboarding, kayaking, and fishing.
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Arts and culture
Local culture blends historic preservation with industrial heritage. Greer Station includes more than forty buildings listed on the National Register of Historic Places, brick-paved walkways, local boutiques, and an escape room, alongside local history exhibits at the Greer Heritage Museum housed in a 1935 post office.
The city hosts signature community gatherings such as Freedom Blast, Greer Goes Global, and live concerts at the Greer City Park amphitheater, while the nearby BMW Performance Center adds a distinctive automotive connection.
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For families
Greer maintains a family-friendly reputation anchored by highly rated public schools, dedicated parks, and active neighborhood associations. Century Park's sprawling Kids Planet playground is a regional gathering spot for children, and established neighborhoods like Sugar Creek organize community events around shared swimming facilities.
Because Greer spans the border of Greenville County and Spartanburg County, families relocating to the area must carefully verify school zoning and district boundaries when selecting a home.
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What locals say
Residents praise Greer for its welcoming small-town atmosphere, vibrant and revitalized downtown district, and convenient central position between Greenville and Spartanburg employment hubs. However, community discussions regularly cite growing pains fueled by rapid Upstate development, noting rising housing demand, increasing suburban sprawl that mandates driving for almost every errand outside downtown, and aggravating rush-hour traffic along major corridors like Wade Hampton Boulevard.
