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29 nursing jobs in Mount Pleasant, SC

Just across the Arthur Ravenel Jr. Bridge from Charleston’s peninsula hospitals, Mount Pleasant offers shift workers a 10-to-15-minute off-peak commute. Between shifts, decompress paddleboarding Shem Creek or watching sunsets on Pitt Street Bridge, before heading home to historic Old Village cottages, walkable I'On, or suburban Carolina Park.

Also hiring: Mount Pleasant, TX (70) · Mount Pleasant, MI (6)

Mount Pleasant, SC on the map· Open the live map
MUSC Children's Health workplace
MUSC Children's Health — a workplace named in a current Mount Pleasant postingView MUSC Children's Health →

Find a nursing job in Mount Pleasant

Hiring here: Novant Health (8) · CHARLESTON ‑ AMG SPECIALTY HOSPITAL (2) · Fresenius Medical Care (2) · MUSC Health (2) · Roper St. Francis Healthcare (2) · Sea Grove Recovery (2)

MUSC Children's Health

Mount Pleasant, SC

  • RN
  • Compact license OK
  • ADN accepted
1 / 2

WOUND CARE NURSE (RN or LPN) FULL TIME

Charleston ‑ AMG Specialty Hospital logoCharleston ‑ AMG Specialty Hospital

Mount Pleasant, SC

  • RN/LPN
  • Day shift
  • Floating required
1 / 4
  • RN
  • Weekend shift
  • Compact license OK
Charleston ‑ AMG Specialty Hospital logo

Charleston ‑ AMG Specialty Hospital

Mount Pleasant, SC

  • Sign-on bonus
  • RN
  • Weekends shift
Roper St. Francis Healthcare logo

Roper St. Francis Healthcare

Mount Pleasant, SC

  • RN
  • Night shift
  • ADN accepted

Cooper River Assisted Living

Mount Pleasant, SC

  • RN
  • Rotating shift

Sea Grove Recovery

Mount Pleasant, SC

  • RN
  • Night shift
  • Tuition reimbursement
Pinnacle Fertility logo

Pinnacle Fertility

Mount Pleasant, SC

  • RN
  • Monday - Friday from 7:30 AM - 4:00 PM

AMG, Integrated Healthcare Management

Mount Pleasant, SC · Health system employer

  • RN/LPN
  • Day shift
  • Floating required
Novant Health logo

Novant Health

Mount Pleasant, SC · Health system employer

Lactation Consultant

Posted last week

  • RN
Restore Hyper Wellness logo

Restore Hyper Wellness

Mount Pleasant, SC

  • RN
Aura Health logo

Aura Health

Mount Pleasant, SC

  • RN
  • Floating required
Option Care Health logo

Option Care Health

Mount Pleasant, SC

  • RN
  • Ambulatory Infusion Clinic (AIC)
  • ADN accepted
MUSC Health logo

MUSC Health

Mount Pleasant, SC · Health system employer

  • RN
  • Compact license OK
  • ADN accepted

Fairview Hospital / Cleveland Clinic

Mount Pleasant, SC

  • RN
Option Care Enterprises, Inc. logo

Option Care Enterprises, Inc.

Mount Pleasant, SC

Nursing Supervisor - Charleston

Posted last week

$80,589–$134,300

  • RN
  • Tuition reimbursement
Fresenius Medical Care logo

Fresenius Medical Care

Mount Pleasant, SC

  • New grads welcomed
  • RN
  • Floating required
Davita logo

Davita

Mount Pleasant, SC

  • Sign-on bonus
  • RN
  • Rotating shift
  • ADN accepted

Sea Grove Recovery

Mount Pleasant, SC

  • RN
  • Day shift
  • Tuition reimbursement

Novant Health

Mount Pleasant, SC

  • RN
  • 12-⁠hour nights
  • Per diem
MUSC Health logo

MUSC Health

Mount Pleasant, SC · Health system employer

  • RN
  • Compact license OK
  • ADN accepted
Fresenius Medical Care logo

Fresenius Medical Care

Mount Pleasant, SC

  • RN
  • ADN accepted
  • Floating required

Novant Health

7 open roles · night & per diem shifts

Registered Nurse - Inpatient Rehab

Mount Pleasant, SC · Posted last week

  • RN

Licensed Practical Nurse

Mount Pleasant, SC

  • LPN
  • Sign-on bonus
  • RN
  • Night shift
  • Floating required

Clinical Supervisor I

Mount Pleasant, SC

  • RN

Registered Nurse

Mount Pleasant, SC

  • RN
  • Per diem
  • ADN accepted

RN Ambulatory Specialty

Mount Pleasant, SC

  • RN

Working and living in Mount Pleasant

· 29 open roles

Living costs

Median gross rent
$2,159/mo
Rent and tenant-paid utilities
Median household income
$124,755/yr
All local households, not nurse pay

Census ACS 2024

Open to new grads

1 postings explicitly welcome new grads.

Browse new grad roles

New to our board this week

0 current postings first appeared here in the past seven days.

Browse current openings

Credentials accepted

  • RN28
  • LPN3

One posting may accept more than one credential.

Shifts listed

  • Days4
  • Nights4
  • per-diem3
  • Rotating2
  • weekend1

Postings may list several shifts or leave the shift unspecified.

Living in Mount Pleasant

Mount Pleasant offers relocating healthcare professionals a polished coastal lifestyle defined by salt marshes, mature live oaks, and quick access to downtown Charleston.

More about life here

Situated just across the Cooper River via the Arthur Ravenel Jr. Bridge, the town allows nurses commuting to peninsula hospitals to reach their units in ten to fifteen minutes off-peak, though rush-hour congestion on US-17 and bridge approaches requires planning. Living here provides immediate access to Sullivan's Island and Isle of Palms beaches, along with paddleboarding on Shem Creek, strolls along the Pitt Street Bridge, and seafood dinners at Tavern & Table.

Lower Mount Pleasant neighborhoods like Old Village and I'On deliver historic character and the shortest commutes at premium price tiers, while Upper Mount Pleasant communities like Carolina Park and Hamlin Plantation offer spacious suburban housing and top-rated schools like Lucy Beckham and Wando High. Tradeoffs include competitive housing markets, omnipresent HOA regulations, heavy summer tourist traffic, and hurricane season weather risks.

For nurses seeking an active coastal base with pristine amenities, Mount Pleasant stands out as an exceptionally balanced coastal suburb.

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As of Sep 16, 2026
Neighborhoods

Mount Pleasant is geographically split between Lower and Upper (North) Mount Pleasant by the Isle of Palms Connector. Lower Mount Pleasant holds established, premium enclaves such as Old Village—a historic waterfront district offering a blend of restored historic homes, mid-century ranches, and Lowcountry cottages—and I'On, an architecturally detailed New Urbanist neighborhood with walkable streets.

Further north, master-planned developments such as Carolina Park, Hamlin Plantation, Brickyard, Seaside Farms, and Snee Farm provide newer, larger suburban builds and community amenities that generally sit at a more accessible tier than waterfront Lower Mount Pleasant.

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Housing

Housing stock ranges from historic properties and mid-century single-family cottages in Old Village to expansive, traditional Lowcountry homes in master-planned subdivisions like I'On and Carolina Park. Lower Mount Pleasant commands premium valuations due to its proximity to the Ravenel Bridge and Charleston Harbor, while Upper Mount Pleasant offers more modern tract housing and condominium options.

Prospective residents should expect strict homeowners association governance across most master-planned developments.

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Getting around

Commutes to major healthcare facilities on the downtown Charleston peninsula depend heavily on the Arthur Ravenel Jr. Bridge, supported by main arteries including US-17 (Johnnie Dodds Boulevard), Coleman Boulevard, and Interstate 526 for access toward North Charleston and Daniel Island. Off-peak drives from South Mount Pleasant into downtown medical centers take roughly ten to fifteen minutes, but morning and evening peak traffic regularly tacks on ten to twenty or more additional minutes, making proximity to the bridge a major consideration for shift workers.

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Food and dining

Mount Pleasant features an active culinary scene centered around fresh coastal seafood and Southern classics. Shem Creek serves as a prime waterfront dining hub with establishments like Tavern & Table and Vickery's offering marsh views and dockside seafood.

Casual daytime staples include Page's Okra Grill and Vicious Biscuit, while evening options range from wood-fired pizza at Coastal Crust to fine dining at Langdon's and Opal, upscale Greek fare at Philosophia, and craft brews at Hobcaw Brewing Company.

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Outdoors

Outdoor recreation revolves around extensive waterways, marshlands, and preserved parks. The 943-acre Palmetto Islands County Park provides nature trails, marsh boardwalks, and canoe rentals, while the Mount Pleasant Memorial Waterfront Park and fishing pier offer open harbor views at the base of the Ravenel Bridge.

Water sports thrive on Shem Creek and along the Wando River for kayaking and paddleboarding, and the historic Pitt Street Bridge serves as a favorite pedestrian causeway for fishing, birdwatching, and sunset walks.

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Arts and culture

Local culture blends Lowcountry maritime heritage with living history and community arts. Major cultural landmarks include the Patriots Point Naval & Maritime Museum—home to the USS Yorktown—and Boone Hall Plantation & Gardens, which highlights Gullah culture and historic brick cabins along its moss-draped Avenue of Oaks.

Community gatherings include the seasonal 'Shaggin' on the Cooper' pier dances, public art displays like the town's painted traffic boxes, and traditional sweetgrass basket weaving stands along highway corridors.

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Seasons and weather

Mount Pleasant experiences a warm coastal subtropical climate marked by long, hot, and humid summers where outdoor life shifts toward barrier island beaches or shaded waterways. Late summer and autumn bring the peak of the Atlantic hurricane season, requiring vigilance regarding tropical systems and coastal flooding.

Winters remain mild and temperate, allowing year-round trail walking and outdoor dining with only occasional brief cold snaps.

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For families

Mount Pleasant is widely regarded as one of South Carolina's most family-focused communities, supported by strong municipal services and visible local policing. The town is served by top-performing Charleston County School District campuses, including Lucy Beckham High School, Wando High School, and Cario Middle School.

Subdivisions such as Carolina Park, Snee Farm, and Hobcaw Creek are especially favored by families for their community pools, athletic fields, and proximity to youth sports facilities.

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What locals say

Residents praise Mount Pleasant for its safe, manicured neighborhoods, pristine county parks, top-rated public schools, and effortless access to Sullivan's Island and Isle of Palms beaches. However, locals frequently voice frustration over high living expenses, heavy summer traffic bottlenecks toward the beaches and bridges, rigid HOA environments in master-planned subdivisions, and persistent risks related to hurricane season and coastal storm surge.

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