164 nursing jobs in Wilmington, DE
Anchored along the Brandywine River, Wilmington pairs powerhouse healthcare systems like ChristianaCare and Nemours with leafy Trolley Square brick rowhomes and riverfront dining. With Delaware’s tax-free shopping and a cost of living about 3% above the national average, nurses gain seamless Northeast Corridor transit access without the crushing overhead of nearby Philadelphia or Baltimore.
Also hiring: Wilmington, NC (90)
Find a nursing job in Wilmington
Hiring here: Nemours Children's Health (57) · Veterans Health Administration (27) · DE_SFHH St. Francis Hospital, Inc. (12) · Select Specialty Hospital - Wilmington (9) · Acts Retirement-Life Communities (6) · ChristianaCare (5)
- Sign-on bonus
- RN
- Night shift
- Tuition reimbursement
Emergency Department Registered Nurse
Wilmington, DE
$68,000–$124,000/year
- RN
- Rotating
- Main ED
Neonatal Nurse Practitioner or Physician Assistant, Part-time
Wilmington, DE · Posted 3 days ago
- NP
- Rotating shift
- RN
- Monday through Fridays: 8am to 4:30pm or 8:30am to 5pm
- ADN accepted
- NP

Nemours Children's Health
4 open roles · night & per diem shifts · Permanent
Nemours Children's Health
4 open roles · night & per diem shifts · Permanent
Pediatric Acute Care Nurse Practitioner or Physician Assistant Trainee - Cardiac Center
Wilmington, DE · Posted last week
- NP
- RN
- Night shift
Pediatric Nurse Practitioner or Physician Assistant, Research
Wilmington, DE · Posted last week
- NP
Neonatal Nurse Practitioner or Physician Assistant
Wilmington, DE · Posted last week
- New grads welcomed
- NP
- Night shift
Registered Nurse (RN) / Days
Up to $56/hr
- Sign-on bonus
- RN
- 12-hour days
- Tuition reimbursement
Registered Nurse - ICU
Posted last week
- RN
- 12-hour days
- New grads welcomed
- RN
- 8-hour days
Registered Nurse, Home Health
$75,000–$100,000/year
- RN
- Day shift
- Tuition reimbursement
Assistant to the doctor
From $18/hr
- RN
- 12-hour nights
- Compact license OK
- RN
- Night shift
- Compact license OK
- RN
- Monday through Fridays: 8am to 4:30pm or 8:30am to 5pm
- ADN accepted
Registered Nurse
$40–$45/hr
- RN
- Day shift
- Per diem
- Sign-on bonus
- RN
- 12-hour days
- Per diem
- RN
- Day shift
- RN
- Day shift
- Sign-on bonus
- RN
- 12-hour days
Registered Nurse - Maternity - Per Diem
Posted last week
- RN
- Night shift
- Per diem
- Sign-on bonus
- RN
- 12-hour days
- Per diem
Registered Nurse - Emergency Department
Posted last week
- RN
- 12-hour rotating
- Sign-on bonus
- RN
- 12-hour nights
- Per diem
Registered Nurse - CVU - Nights
Posted last week
- RN
- 12-hour nights
- RN
- 12-hour days
- Per diem
Registered Nurse - CVU - Per Diem
Posted last week
- RN
- Rotating shift
- Per diem
Working and living in Wilmington
· 164 open roles
Living costs
- Median gross rent
- $1,224/mo
- Rent and tenant-paid utilities
- Median household income
- $58,671/yr
- All local households, not nurse pay
New to our board this week
9 current postings first appeared here in the past seven days.
Credentials accepted
- CRNA1
- NP22
- APRN1
- RN120
- LPN8
- CNA3
One posting may accept more than one credential.
Shifts listed
- Days43
- Nights38
- per-diem21
- Rotating17
- Evenings6
- weekend4
Postings may list several shifts or leave the shift unspecified.
Living in Wilmington
Wilmington sits where the Christina meets the Brandywine: a compact banking city on the Amtrak Northeast Corridor, about 30 minutes from Philadelphia, with no sales tax and median home values around $260,000. That is the real draw—East Coast access without East Coast housing.
More about life hereShow less
Walkable nights mean Trolley Square’s Victorian rowhouses and bars, or a downtown conversion near the Joseph R. Biden Jr. Railroad Station, the Grand Opera House, and tables at Bardea, Deco, or Le Cavalier in the Hotel du Pont; after 5 p.m. the office sidewalks empty. Buying usually means The Highlands’ stone houses, Rockford Park, 9th Ward Craftsman streets, or suburban Claymont, Bellefonte, and Pike Creek.
Days off run to Brandywine Park’s 178 acres and zoo, the two-mile Christina riverwalk, Alapocas Run’s granite cliffs, and free Clifford Brown Jazz Festival nights at Rodney Square; beaches sit about an hour 20 minutes down Route 1. Tradeoffs: DART and SEPTA thin off-peak so most people drive I-95, medical appointments can take weeks, and downtown is more workplace than neighborhood after dark.
Sources
Neighborhoods
Nurses and young professionals who want city life typically land in Trolley Square (Victorian rowhouses, walkable bars and dining), Little Italy, Cool Spring, and Hilltop, or in Downtown mid- and high-rise apartments and office conversions along Market Street and Delaware Avenue. The Highlands is the premium old-house district—grand stone homes, park views, and museum culture up by Rockford Park—while Trinity Vicinity has historic brick rowhouses and riverside parks, and the 9th Ward Area is the Craftsman-house, tree-lined-boulevard buy.
North of the city, Bellefonte and Claymont are the usual recommendations, with Pike Creek and North Wilmington the suburban family band around a $350k budget; Governors House is a budget-friendly condo community with U.S. 13 and I-495 access. Columbia Place is a newer active-adult community with clubhouse, fitness center, and walking paths, Westhampton appears on local best-of lists, and Newark and historic New Castle are the nearby-town alternatives.
Sources
Housing
U.S. News lists a median home value of $263,535 and median rent of $1,123; Apartment Guide puts average one-bedroom rent at $1,875 and median sale price at $260,000, so rent quotes disagree by source while purchase prices cluster near $260k, below the national median home value of $359,870. Downtown is almost all apartments, studios to two-bedrooms, many converted from offices; as of June 2026 about 35% of downtown rentals on Trulia list a gym versus roughly 8% citywide, and there are no true single-family houses at the center. Buying a house generally means going north of the parks: Highlands stone houses, Trolley Square Victorians, Trinity Vicinity brick rowhouses, 9th Ward Craftsman homes.
Governors House is the budget condo option; Claymont, North Wilmington, and Pike Creek are the roughly $350k family suburban tier, and boosters emphasize lower housing costs than nearby East Coast cities.
Getting around
Wilmington sits on the Amtrak Northeast Corridor; Downtown residents can walk to the Joseph R. Biden Jr. Railroad Station for Amtrak and SEPTA Regional Rail to Philadelphia in about 30 minutes, and DART First State buses converge on Rodney Square, so a car-free downtown life is possible. I-95 cuts through the middle of the city, U.S. 13 and I-495 serve the eastern condo side, and the average commute is about 19.9 minutes, but DART and SEPTA coverage and frequency drop outside peak hours, so most people still keep a car.
Downtown street parking is metered and tight; a garage is the practical default. Philadelphia is about 30 minutes by train or car, Baltimore about an hour by car (about 1.5 hours by train), Washington, D.C. about two hours, New York about 1.5 hours by train, and the Delaware beaches about an hour 20 minutes south on Route 1.
Food and dining
Downtown is the chef scene: Bardea, a modern Italian bistro that opened in 2018 and was named a James Beard Award semifinalist; Torbert Street Social, a speakeasy cocktail bar in a historic brick building; Deco, a contemporary food hall used as a launchpad for local chefs; and Le Cavalier, a French brasserie with Provence and North African influences in the Hotel du Pont’s Green Room. Trolley Square is the walkable dining-and-bar strip, Little Italy the named neighborhood for Italian character, and the Christina Riverfront mixes restaurants with the two-mile riverwalk.
Reddit locals flag Scout Cafe, Karma, and Sleeping Bird for food and coffee. Shopping is tax-free statewide.
Outdoors
Brandywine Park is Delaware’s largest urban park at 178 acres, on the National Historic Register since 1976, with wooded trails, formal gardens, sculptures, a sports stadium, and Brandywine Zoo in the heart of the city. Rockford Park has a 100-year-old stone tower, tennis, and wooded paths; Alapocas Run State Park has mature woodlands, blue granite cliffs, and Blue Ball Barn; Bellevue State Park has a DuPont mansion, fishing pond, and trails; Brandywine Creek State Park has miles of hiking and fishing.
The Riverfront’s two-mile riverwalk along the Christina River leads to the DuPont Environmental Education Center’s freshwater tidal marsh; the city lists more than 70 parks, plus the accessible Can-Do Playground. Delaware beaches are about an hour 20 minutes to an hour and a half south.
Arts and culture
Market Street is the theater spine: the Grand Opera House (1871, cast-iron facade, a full season), the Hotel du Pont at 11th and Market since 1913 and its Playhouse, plus Delaware Theatre Company. Museums and estates include the Delaware Art Museum, Delaware Contemporary (free admission), Delaware History Museum, Winterthur Museum Garden and Library, Hagley Museum and Library, Nemours Estate, Rockwood Park and Museum, the Kalmar Nyckel, and Gloria Dei (Old Swedes’) Episcopal Church.
Rodney Square hosts the Clifford Brown Jazz Festival, described as the largest multi-day free outdoor music festival on the East Coast; the Riverfront Blues Festival draws the region; Trolley Square is the busiest bar scene with weekend live music. Frawley Stadium, Brandywine Zoo, and the Delaware Children’s Museum cover sports and family culture.
Sources
Seasons and weather
Apartment Guide reports an average summer high of 86°F and about 202 days of sunshine a year, which matches the visitor-bureau pitch of mid-Atlantic warm weather and easy beach weekends. From Wilmington the Delaware beaches are about an hour 20 minutes south on Route 1, so summer is the season people actually use.
A relocation video treats Northern Delaware weather as its own topic, but the available transcript does not give winter snowfall or shoulder-season numbers. Plan on hot summers, a long stretch of usable park and riverwalk days, and a four-season Mid-Atlantic year without source-stated snow totals.
Sources
For families
Facebook commenters point families with about a $350k budget to Claymont, North Wilmington, and Pike Creek for suburban settings and good schools. Named kid amenities include Brandywine Zoo, the Delaware Children’s Museum, the accessible Can-Do Playground, Frawley Stadium, Fred Rust Ice Arena, and Winterthur; Brandywine Park’s 178 acres and more than 70 city parks are the everyday outdoor fabric.
These sources do not name school districts or publish ratings. Safety is raised as a relocation-video chapter without a verdict in the provided transcript, and some Delaware-move threads mention overcrowding in certain areas.
What locals say
People who like Wilmington cite no sales tax, relatively low property taxes, a small-world network once you know people, housing cheaper than nearby East Coast cities, and a 30-minute shot to Philadelphia. Recurring complaints are that you need a car because transit is thin, traffic and overcrowding in some areas, downtown emptying after the workday, and medical appointments that can take weeks or months.
U.S. News scores the city 4.4/10 overall (#806 Best Places to Live, #2 in Delaware) with a 3.6/10 value index versus similarly sized cities, median household income of $59,693, and unemployment of 7.63%. The local lifestyle fork is almost always in-city walkability (Trolley Square, Little Italy) versus suburban Claymont, North Wilmington, or Pike Creek.