21 nursing jobs in Spartanburg, SC
Spartanburg sits in South Carolina's Upstate, blending small-city charm with easy access to the Blue Ridge foothills. Known as the 'Hub City' for its historic rail crossroads, it offers nurses a relaxed pace, growing healthcare networks, and proximity to Greenville and Charlotte for bigger-city amenities.

Find a nursing job in Spartanburg
Hiring here: Spartanburg Regional Healthcare System (7) · White Oak Management, Inc. (2) · ACG Hospice (1) · American Traveler (1) · BioLife Plasma Services (1) · Charles Lea Center (1)
- LPN
- 12-hour weekends only
- +$8/hr differential
- LPN
- Per diem
- New grads welcomed · reported
- RN
- Day shift
Paramedic or LPN - Part Time Plasma Center Medical Support Specialist
$27/hr
Spartanburg, SC
- LPN
- Tuition reimbursement
Licensed Practical Nurse
$28/hr
Spartanburg, SC
- RN
- Day shift
Hospital Dialysis Registered Nurse - Upstate Float
Spartanburg, SC · Posted 6 days ago
- RN
- Rotating shift
- ADN accepted
Nurse-Employee Health
Spartanburg, SC · Seen active yesterday
- RN
- ADN accepted
Registered Nurse (RN) (Spartanburg)
Spartanburg, SC
- RN
- Ratio 1:5
- 8-hour days
Spartanburg Regional Healthcare System
7 open roles
Spartanburg Regional Healthcare System
7 open roles
Registered Nurse (RN)- SMC 5 Main
Spartanburg, SC
- Sign-on bonus
- RN
- Day shift
- Compact license OK
Registered Nurse-Ortho Trauma
Spartanburg, SC · Seen active last week
- New grads welcomed
- RN
- Orthopedic Trauma unit
Nurse-Clinic
Spartanburg, SC
- RN
Registered Nurse PRN Tier (RN) 1- SMC Emergency Center
Spartanburg, SC
- New grads welcomed · reported
- RN
- Per diem
- Compact license OK
PRN Registered Nurse (RN)- Behavioral Health
Spartanburg, SC
- RN
- Per diem
- Compact license OK
Registered Nurse (RN) - Nursery Intensive (NICU)
Spartanburg, SC
- RN
- RN
- Ratio 1:5
- Night shift
Working and living in Spartanburg
· 21 open roles in this snapshot
Living costs
- Median gross rent
- $1,099/mo
- Rent and tenant-paid utilities
- Median household income
- $51,964/yr
- All local households, not nurse pay
New to our board this week
4 current postings first appeared here in the past seven days.
Credentials accepted
- NP2
- RN15
- LPN4
One posting may accept more than one credential.
Shifts listed
- Days5
- per-diem4
- Rotating2
- Nights1
- weekend1
Postings may list several shifts or leave the shift unspecified.